These tools are very useful for either a better comprehension of cancer physiopathology or even cell lines qualification. They can also be The tool to define the therapeutical protocol.
2. Réf.
Generalpresentation-Confidential
2 - 06/02/2017
Rational for proteomic quantification (MS2plex®) in
cancer management
Tumor heterogeneity is now well demonstrated and a
critical issue (between/within patients)
This impairs the rational selection a therapeutic
strategy
Identification of subtypes is achieved by Molecular
Biology (not directly linked to protein
expression/function) and through antibodies (with
specificity and throughput issues)
MS2plex®, new alternative to allow the measurement
of up to 21 different markers in a single run
4. Réf.
Generalpresentation-Confidential
4 - 06/02/2017
Membrane proteins in plasma membrane fraction expression levels of
tumor tissues useful for an appropriate drug selection for the individual
treatment of brain tumor
Patient having an anaplastic meningioma with metastatic lesion
remaining after surgery & radiotherapy
* Platelet derived growth factor receptor
*
Biomarker applications: identifying accurate target
receptor (clinical study case)
NeuropathologyandAppliedNeurobiology(2012),38,105–110
5. Réf.
Generalpresentation-Confidential
5 - 06/02/2017
Biomarker applications: identifying accurate target
receptor (clinical study case)
Sunitinib (marketed as Sutent), an oral SMI of multi-
targeted receptor tyrosine kinase approved for the
treatment of renal cell carcinoma used as adjuvant
chemotherapy
NeuropathologyandAppliedNeurobiology(2012),38,105–110
7. Thank you for your attention!
For additional details, we remain at your entire service
Take a chance to visit our website:
bertinpharma.com
Thank you for your attention!
For additional details, we remain at your entire service
Take a chance to visit our website: