This study examined the effects of manual therapy techniques on 5 former professional football players with histories of concussion. The players underwent cognitive, pain, and mobility tests before and after a 5-day intensive manual therapy program. The therapies aimed to address post-concussion imbalances and included craniosacral, visceral, and neuromeningeal techniques. Results showed improvements in quality of life, depression symptoms, sleep, pain levels, and range of motion. However, the small sample size and lack of controls were limitations; further research with more participants is needed to validate the findings.