The document discusses cocaine, including that it is made from the coca plant native to South America. It can be taken as powder, liquid, or crack crystal form by snorting, injecting, or smoking. Cocaine provides a short-term high by inhibiting dopamine reuptake but also has negative side effects. A new vaccine in development works by binding to cocaine to prevent its effects. The vaccine may help treat addiction but is unlikely to eliminate it completely due to social and behavioral factors also influencing drug use.

1. By: Jennifer Schmuck

2.  Bump
 Blow
 Candy
 Charlie
 C
 Crack
 Rock
 Cocaine
hydrochloride
topical solution
 Used in certain
medical procedures

3.  Cocaine is made from the plant coca which is
a native plant from South Africa
 Can be produced in three forms Powder,
Liquid and powder mixture, and Crystal Rock
(Crack)

4.  Most common way
of using Cocaine:
◦ Snorted
◦ Injected with water
solution into Blood
Stream
◦ Smoked: When in
Crack form

5.  Cocaine is a nuerological stimulant that
effects the nervous system
◦ Therefore short term high involves:
 Euphoria
 Energy
 Talkativeness
 High Blood Pressure
 Racing Heart Rate

6.  Cocaine only gives a temporary high lasting
at most 30 minutes if snorted, with injection
and inhalation highs only last for 5 to 10
mins
 This makes addicts seek binge like behaviors
to create a lasting high

7.  Cocaine effects the brain and inhibits dopamine
within the brain
 Dopamine is the chemical released when
someone smells good food and feels a sense of
pleasure
 With excess dopamine people will experience the
characteristic high but also
◦ dilated pupils
◦ Constricted blood vessels
◦ Headaches
◦ Increased body temperature
◦ Can lead to stroke and other physical health problems

8.  Recent studies have found success in a
cocaine vaccine
 This vaccine binds the cocaine and does not
allow the chemical reaction of dopamine to
occur
 Without excess dopamine the body does not
have the same effect to cocaine
 http://www.nature.com/npp/journal/v38/n1
1/full/npp2013114a.html

9.  Do you feel that the new vaccine being tested
will eliminate cocaine and crack addicts? Why
or Why Not?

10. 1. (n.d.). Retrieved March 4, 2015, from
http://www.drugabuse.gov/drugs-
abuse/commonly-abused-drugs/commonly-
abused-drugs-chart.
2. DrugFacts: Cocaine. (n.d.). Retrieved March 2,
2015, from
http://www.drugabuse.gov/publications/drugfa
cts/cocaine
3. Maoz, A., Hicks, M., Vallabhjosula, S., Synan, M.,
Kothrai, P., Dyke, J., ... Kaminsky, S. (2013).
Adenovirus Capsid-Based Anti-Cocaine Vaccine
Prevents Cocaine from Binding to the Nonhuman
Primate CNS Dopamine Transporter.
Neuropsychopharmacology, 38, 2170-2178.