Chronic Tension-type headache is the most common type of headache encountered in clinical setup. This study aims to examine the clinical profile of patients suffering from chronic Tension-type headache.
Pain in the elderly. How to better understand and rate it.Ross Finesmith M.D.
It is often difficult to determine the amount of pain an elderly person is experiencing.This is complicated by dementia and verbal impairment. This presentation describes helpful methods to assess pain in the elderly.
Experience of a comprehensive pain care (cpc) clinic from a provincial gener...Rohitha Jayamaha
1) The document describes the experience of establishing a Comprehensive Pain Care (CPC) Clinic at a Provincial General Hospital in Sri Lanka. A survey found that chronic pain was a major complaint for many outpatients.
2) In response, the hospital set up a CPC Clinic using a multidisciplinary approach to assess, treat, and manage chronic pain through both invasive and non-invasive methods.
3) Over 25 months, the CPC Clinic treated over 2,000 patients, with around 22% receiving interventional pain procedures. The holistic CPC model focused on patient-centered care and lifestyle changes rather than individual treatment approaches.
Acupuncture has become more widely used in sports medicine to treat pain and hasten recovery from injuries. Modern acupuncture uses sterile, disposable needles inserted at specific points along "meridians" to balance the flow of life energy in the body. Treatment sessions typically involve 6-12 needles placed for 10-30 minutes. While generally safe, serious risks include infection and organ puncture. Research shows acupuncture effective for osteoarthritis knee pain and some studies find it can improve immune function after exercise. The largest trial to date found acupuncture helped reduce knee pain more than education or sham acupuncture.
New Results from National Institutes of Health R01 GrantAllina Health
This document summarizes the results of a National Institutes of Health grant studying integrative medicine (IM) at a large hospital. Key findings include:
- Median time to first IM referral varied by clinical service line, from under 5 hours for oncology to over 2 days for mental health.
- Analysis of IM therapies for joint replacement, oncology, and cardiovascular patients found significant reductions in pain and anxiety scores post-treatment.
- A pilot study of acupuncture in the emergency department found it reduced pain scores significantly, with many patients able to avoid opioid pain medications.
- Future studies are planned to analyze the data and publish results in 2016-2017, including understanding factors influencing IM therapy selection and examining
This study examined the effects of craniosacral therapy (CST) on heart rate variability (HRV) in 31 patients with subjective discomforts. HRV was measured before and after a 30-minute control rest period and a 30-minute CST session on consecutive days using a mobile device. Standard deviation of heart rate intervals (SDNN) and total power (TP), indicators of autonomic nervous system activity, increased significantly after CST but not the control rest. Heart rate also decreased significantly after CST compared to rest. However, interactions between treatment and HRV changes were not fully statistically significant. The study provides preliminary evidence that CST may positively influence autonomic nervous system regulation.
This randomized controlled trial investigated whether acupuncture or sham acupuncture was more effective than no acupuncture in reducing migraine headaches in 302 patients. The trial found that both acupuncture and sham acupuncture led to greater reductions in moderate or severe headache days compared to the waiting list control group. However, acupuncture was not found to be more effective than sham acupuncture for reducing headache days. The proportion of "responders", defined as at least a 50% reduction in headache days, was similar between the acupuncture (51%) and sham acupuncture (53%) groups, and higher than the waiting list group (15%). The trial concluded that acupuncture was no more effective than sham acupuncture for reducing migraine headaches, although both were more
Case Study Nursing Management in Pathophysiologyemilyparker01
Thank you for the feedback. You're right that including more in-text citations would have strengthened the responses. In the future, I will aim to better support my answers with references as appropriate. The comments provide helpful guidance on how I can continue improving my summarization and analysis skills.
Efficacy of classification-based_cft_in_nsclbpMeziat
Artigo (6) importante para a preparação para o curso de dor lombar crônica. "Eficácia da Terapia Cognitiva Funcional em pacientes com dor lombar crônica inespecífica: ensaio clínico randomizado controlado."
Pain in the elderly. How to better understand and rate it.Ross Finesmith M.D.
It is often difficult to determine the amount of pain an elderly person is experiencing.This is complicated by dementia and verbal impairment. This presentation describes helpful methods to assess pain in the elderly.
Experience of a comprehensive pain care (cpc) clinic from a provincial gener...Rohitha Jayamaha
1) The document describes the experience of establishing a Comprehensive Pain Care (CPC) Clinic at a Provincial General Hospital in Sri Lanka. A survey found that chronic pain was a major complaint for many outpatients.
2) In response, the hospital set up a CPC Clinic using a multidisciplinary approach to assess, treat, and manage chronic pain through both invasive and non-invasive methods.
3) Over 25 months, the CPC Clinic treated over 2,000 patients, with around 22% receiving interventional pain procedures. The holistic CPC model focused on patient-centered care and lifestyle changes rather than individual treatment approaches.
Acupuncture has become more widely used in sports medicine to treat pain and hasten recovery from injuries. Modern acupuncture uses sterile, disposable needles inserted at specific points along "meridians" to balance the flow of life energy in the body. Treatment sessions typically involve 6-12 needles placed for 10-30 minutes. While generally safe, serious risks include infection and organ puncture. Research shows acupuncture effective for osteoarthritis knee pain and some studies find it can improve immune function after exercise. The largest trial to date found acupuncture helped reduce knee pain more than education or sham acupuncture.
New Results from National Institutes of Health R01 GrantAllina Health
This document summarizes the results of a National Institutes of Health grant studying integrative medicine (IM) at a large hospital. Key findings include:
- Median time to first IM referral varied by clinical service line, from under 5 hours for oncology to over 2 days for mental health.
- Analysis of IM therapies for joint replacement, oncology, and cardiovascular patients found significant reductions in pain and anxiety scores post-treatment.
- A pilot study of acupuncture in the emergency department found it reduced pain scores significantly, with many patients able to avoid opioid pain medications.
- Future studies are planned to analyze the data and publish results in 2016-2017, including understanding factors influencing IM therapy selection and examining
This study examined the effects of craniosacral therapy (CST) on heart rate variability (HRV) in 31 patients with subjective discomforts. HRV was measured before and after a 30-minute control rest period and a 30-minute CST session on consecutive days using a mobile device. Standard deviation of heart rate intervals (SDNN) and total power (TP), indicators of autonomic nervous system activity, increased significantly after CST but not the control rest. Heart rate also decreased significantly after CST compared to rest. However, interactions between treatment and HRV changes were not fully statistically significant. The study provides preliminary evidence that CST may positively influence autonomic nervous system regulation.
This randomized controlled trial investigated whether acupuncture or sham acupuncture was more effective than no acupuncture in reducing migraine headaches in 302 patients. The trial found that both acupuncture and sham acupuncture led to greater reductions in moderate or severe headache days compared to the waiting list control group. However, acupuncture was not found to be more effective than sham acupuncture for reducing headache days. The proportion of "responders", defined as at least a 50% reduction in headache days, was similar between the acupuncture (51%) and sham acupuncture (53%) groups, and higher than the waiting list group (15%). The trial concluded that acupuncture was no more effective than sham acupuncture for reducing migraine headaches, although both were more
Case Study Nursing Management in Pathophysiologyemilyparker01
Thank you for the feedback. You're right that including more in-text citations would have strengthened the responses. In the future, I will aim to better support my answers with references as appropriate. The comments provide helpful guidance on how I can continue improving my summarization and analysis skills.
Efficacy of classification-based_cft_in_nsclbpMeziat
Artigo (6) importante para a preparação para o curso de dor lombar crônica. "Eficácia da Terapia Cognitiva Funcional em pacientes com dor lombar crônica inespecífica: ensaio clínico randomizado controlado."
Tapering Long Term Opioid Therapy in Chronic Noncancer PainAde Wijaya
1) Tapering long-term opioid therapy in patients with chronic non-cancer pain can cause withdrawal symptoms and increased pain in the short term or relapse and reduced function in the long term.
2) A slow taper of 10% reduction every 5-7 days is recommended to minimize withdrawal symptoms and improve adherence. Adjunct therapies and psychological support may help during the taper.
3) Optimized nonopioid treatment, interventional procedures, and addressing factors like depression can improve taper outcomes for patients on long-term opioid therapy for chronic non-cancer pain.
MAP0004, an orally inhaled formulation of dihydroergotamine (DHE), was evaluated in a randomized, double-blind, placebo-controlled study for the acute treatment of migraine. 903 patients experiencing a migraine attack were randomized to receive either MAP0004 (0.63 mg emitted dose) or placebo via inhalation. The primary endpoints were pain relief and absence of photophobia, phonophobia, and nausea at 2 hours. MAP0004 was superior to placebo for all primary endpoints. A greater percentage of patients treated with MAP0004 experienced pain relief, absence of photophobia, absence of phonophobia, and absence of nausea compared to those receiving placebo. MAP0004 was well tolerated with no serious
The role of emotional factors in glaucoma has received wide recognition by investigators and clinicians from the very beginning. Prevalence of depression in glaucoma has been estimated to be 10 to 12 percent in previous studies. Insomnia is another psychiatric co-morbidity reported with glaucoma. Both depression and insomnia in glaucoma patients may significantly affect overall quality of life in these patients adversely. The present study explores the predictive factors of insomnia and depression in patients with Glaucoma. A case-series type of observational study was carried out on 100 glaucoma cases attended at ESIC Model Hospital, Jaipur (Rajasthan) India. The PHQ -9 and ISI were used to assess depression and insomnia respectively. Data in details were collected as per pre-designed Performa. Data collected were analyzed and inferred with chi-square test. Insomnia and depression was found in 37% and 36% respectively in glaucoma cases. Insomnia and depression both were found associated with Age, Visual acuity in both the eyes and severity of glaucoma. No other studied socio-demographic and disease variables had significant association with either insomnia or depression. It was concluded that insomnia and depression are commonly found with glaucoma. Both insomnia and depression were found significantly more in older agr group, less visual acuity and sever glaucoma than their counterparts.
Neurotocism and maladaptive coping in patients with functional somatic syndro...Paul Coelho, MD
1) The study investigated neuroticism and maladaptive coping in patients with functional somatic syndromes (FSS) using data from a previous randomized controlled trial.
2) It found that patients with FSS showed higher levels of neuroticism than healthy groups. Neuroticism was linked to poorer physical health indirectly through symptom catastrophizing.
3) Treatment with cognitive-behavioral therapy (CBT) reduced symptom catastrophizing, and this partially mediated the long-term improvement in outcomes from CBT. The results support a cognitive-behavioral model of FSS.
Persistent pain is common in older adults and can cause functional impairment, falls, depression, decreased appetite, impaired sleep, and social isolation. The goal of pain treatment in the elderly is to reduce pain-related disability rather than just pain intensity and involves a multidisciplinary approach including patient education. Successful pain management requires an individualized approach considering physiological changes, comorbidities, and risks of drug interactions when selecting and dosing analgesics like acetaminophen, topical NSAIDs, opioids, and antineuropathic medications. Close monitoring is needed due to increased risk of side effects.
Artigo (acupuntura) - Acupuntura e seus riscosRenato Almeida
This review analyzed 57 systematic reviews and 95 case reports regarding acupuncture for pain. The systematic reviews showed inconsistent and contradictory results, with only neck pain having unanimously positive conclusions from high quality reviews. Numerous caveats and contradictions emerged from the reviews. Case reports identified 95 cases of severe adverse effects from acupuncture, including 5 deaths, with pneumothorax and infections being most common. The review concluded that the evidence does not convincingly demonstrate acupuncture is effective for pain relief and that serious adverse effects continue to be reported.
Anxiety and depression affect nearly every other condition and complaint in the body. Overwhelming stress can render conventional treatments useless. Acupuncture can restore balance, reduce the stress response, disrupt the pathways of stress and reduce the effects of overwhelming burdens so that doctors are able to effectively treat even their most difficult cases.
The conundrum of opioid tapering in long term opioid therapy for chronic pain...Paul Coelho, MD
The document discusses the challenges clinicians face when tapering patients off long-term opioid therapy for chronic pain. It explains that opioid dependence can cause worsening pain, psychiatric symptoms, and functioning during tapering due to neuroplastic changes. While tapering seems logical to address risks of high-dose opioids, it may paradoxically make a patient's issues worse due to protracted abstinence syndrome. The document provides guidance for managing these complex patients focused on both pain and opioid dependence.
This randomized controlled trial compared the effectiveness of virtual reality graded exposure therapy (VR-GET) to treatment as usual (TAU) for active duty service members with combat-related post-traumatic stress disorder (PTSD). 19 participants were randomly assigned to either VR-GET (10 participants) or TAU (9 participants). VR-GET consisted of VR exposure combined with skills training, while TAU included various PTSD treatments like prolonged exposure therapy. Results found that 7 of 10 in the VR-GET group improved by at least 30% on the Clinician Administered PTSD Scale, compared to only 1 of 9 in the TAU group, indicating VR-GET was more effective for treating combat-related PTSD.
Effect of homeopathy on chronic tension-type headache: a pragmatic, randomise...home
Homeopathy is increasingly used by headache patients in
general practice but scientific evidence is lacking. We
therefore designed a clinical trial in a way that would not
change the practice pattern of homeopathic physicians.
The document provides a critical analysis of claims made in a 2012 study by Lozano et al regarding the rationale for selecting the subcallosal cingulate gyrus as a target for deep brain stimulation to treat treatment-resistant depression. The analysis finds that the evidence cited by Lozano et al. to support the involvement of the subcallosal cingulate gyrus in processing acute sadness is insufficient. Several of the cited studies do not specifically implicate this brain region or have limitations such as small sample sizes that weaken their conclusions. The analysis concludes the evidence presented is not adequate to definitively support targeting the subcallosal cingulate gyrus with deep brain stimulation.
This randomized clinical trial tested the effectiveness of stellate ganglion block (SGB) treatment compared to a sham procedure for reducing posttraumatic stress disorder (PTSD) symptoms over 8 weeks. 113 active-duty service members with PTSD symptoms were randomly assigned to receive either 2 SGB treatments 2 weeks apart or a sham procedure. The primary outcome was change in PTSD symptom severity scores measured by the CAPS-5 scale from baseline to 8 weeks. Participants receiving SGB had a greater reduction in symptoms scores compared to the sham group, with adjusted mean decreases of 12.6 vs 6.1 points respectively, indicating SGB treatment may help reduce PTSD symptoms.
Primary Headache Associated with Sexual Activity Ade Wijaya
This document defines and discusses primary headache associated with sexual activity (PHASA). It presents that PHASA involves headache brought on by sexual activity, most commonly a dull bilateral pain that increases with excitement and peaks around orgasm. It can last 1 minute to 72 hours. The document outlines that PHASA is diagnosed through exclusion of other causes and can be treated acutely with indomethacin or triptans or prevented with indomethacin, triptans, or beta blockers like propranolol for 2-6 months.
This study surveyed behavioral health clinicians with experience using stellate ganglion block (SGB) as an adjunct treatment for trauma-related disorders like PTSD. Of the 23 respondents, 95% would recommend SGB to colleagues. Respondents rated SGB as at least as useful as the highest rated standard PTSD interventions. SGB was seen as most helpful for reducing arousal/reactivity symptoms. The majority would refer patients for SGB at any stage of therapy, including before starting other treatments.
This document summarizes various interventional treatments for headaches including occipital nerve blocks, pulsed radiofrequency of the occipital nerve, and occipital nerve stimulation. It provides epidemiological data on migraine and cluster headaches. It also discusses indications for occipital nerve blocks including various headache types. Peripheral nerve blocks are described as commonly used but with variable methodology. Effectiveness of occipital nerve stimulation is supported for various intractable headache conditions but lead migration is a technical challenge.
No poison can kill a positive thinker and no medicine can cure a negative thinker. Pain is a complex perceptual experience. Pain is a major public health problem. Beat back pain without surgery and conquer pain without painkillers. Delays have dangerous ends. Knee braces invite injury. Chronic pain affects one in three people in the United States. There are more Americans suffering from chronic pain than with diabetes, heart disease, and cancer combined. Chronic pain is caused by degeneration, illnesses, injuries, surgeries, and treatment side effects. Pain is a major public health problem and is the most common reason why Americans use complementary and integrative health practices. Recent imaging evidence suggests a possible hypothalamic origin for a headache attack, but further research is needed. A migraine is associated with a modest increase in the risk of ischemic stroke.
This document discusses strategies to prevent and manage delirium in critically ill patients. It outlines the ABCDEF bundle which includes assessing, preventing, and managing pain, both spontaneous awakening and breathing trials, minimizing sedation, assessing and preventing delirium, early mobility and exercise, and engaging family members. Screening for delirium using the CAM-ICU tool and implementing non-pharmacological interventions can reduce length of hospital stay, duration of mechanical ventilation, and mortality. Widespread use of protocols and bundles that incorporate these strategies may help address the high cost and poor outcomes associated with delirium.
A single blind RCT to evaluate the effect of intraoperative bupivacaine infilteration fro post operative pain relief was conducted. Observations based on the VAS and mean duration for requirement of 1st analgesic dose post operatively. Results compared with other similar studies and found that the there is significant reduction in the VAS of post operative pain and increase in the duration for requirement for the 1st dose of the analgesic postoperatively
The volume of Big data is increasing in gigabytes day by day which are hard to make sense and difficult to analyze. The challenges of big data are capturing, storing, searching, sharing, analysis and visualization of these datasets. Big data leads to clutter in their visualization. Clutter is a crowded or disordered collection of graphical entities in information visualization. It can blur the structure of data. In this paper, we present the concept of clutter based dimension reduction. Our purpose is to reduce clutter without reducing information content or disturb data in any way. Dimension reduction is a technique that can significantly reduce the dimensions of the datasets. Dimensionality reduction is useful in visualizing data, discovering a compact representation, decreasing computational processing time and addressing the curse of dimensionality of high-dimensional spaces.
In this paper, we provide a detailed description of methodology for deriving and applying Electronic Commerce (EC) security countermeasures design models from the existing IT standards. Our goal is to describe a model-based approach of how to extend such a model or “specialize” it in order to apply it to e-commerce systems.
Tapering Long Term Opioid Therapy in Chronic Noncancer PainAde Wijaya
1) Tapering long-term opioid therapy in patients with chronic non-cancer pain can cause withdrawal symptoms and increased pain in the short term or relapse and reduced function in the long term.
2) A slow taper of 10% reduction every 5-7 days is recommended to minimize withdrawal symptoms and improve adherence. Adjunct therapies and psychological support may help during the taper.
3) Optimized nonopioid treatment, interventional procedures, and addressing factors like depression can improve taper outcomes for patients on long-term opioid therapy for chronic non-cancer pain.
MAP0004, an orally inhaled formulation of dihydroergotamine (DHE), was evaluated in a randomized, double-blind, placebo-controlled study for the acute treatment of migraine. 903 patients experiencing a migraine attack were randomized to receive either MAP0004 (0.63 mg emitted dose) or placebo via inhalation. The primary endpoints were pain relief and absence of photophobia, phonophobia, and nausea at 2 hours. MAP0004 was superior to placebo for all primary endpoints. A greater percentage of patients treated with MAP0004 experienced pain relief, absence of photophobia, absence of phonophobia, and absence of nausea compared to those receiving placebo. MAP0004 was well tolerated with no serious
The role of emotional factors in glaucoma has received wide recognition by investigators and clinicians from the very beginning. Prevalence of depression in glaucoma has been estimated to be 10 to 12 percent in previous studies. Insomnia is another psychiatric co-morbidity reported with glaucoma. Both depression and insomnia in glaucoma patients may significantly affect overall quality of life in these patients adversely. The present study explores the predictive factors of insomnia and depression in patients with Glaucoma. A case-series type of observational study was carried out on 100 glaucoma cases attended at ESIC Model Hospital, Jaipur (Rajasthan) India. The PHQ -9 and ISI were used to assess depression and insomnia respectively. Data in details were collected as per pre-designed Performa. Data collected were analyzed and inferred with chi-square test. Insomnia and depression was found in 37% and 36% respectively in glaucoma cases. Insomnia and depression both were found associated with Age, Visual acuity in both the eyes and severity of glaucoma. No other studied socio-demographic and disease variables had significant association with either insomnia or depression. It was concluded that insomnia and depression are commonly found with glaucoma. Both insomnia and depression were found significantly more in older agr group, less visual acuity and sever glaucoma than their counterparts.
Neurotocism and maladaptive coping in patients with functional somatic syndro...Paul Coelho, MD
1) The study investigated neuroticism and maladaptive coping in patients with functional somatic syndromes (FSS) using data from a previous randomized controlled trial.
2) It found that patients with FSS showed higher levels of neuroticism than healthy groups. Neuroticism was linked to poorer physical health indirectly through symptom catastrophizing.
3) Treatment with cognitive-behavioral therapy (CBT) reduced symptom catastrophizing, and this partially mediated the long-term improvement in outcomes from CBT. The results support a cognitive-behavioral model of FSS.
Persistent pain is common in older adults and can cause functional impairment, falls, depression, decreased appetite, impaired sleep, and social isolation. The goal of pain treatment in the elderly is to reduce pain-related disability rather than just pain intensity and involves a multidisciplinary approach including patient education. Successful pain management requires an individualized approach considering physiological changes, comorbidities, and risks of drug interactions when selecting and dosing analgesics like acetaminophen, topical NSAIDs, opioids, and antineuropathic medications. Close monitoring is needed due to increased risk of side effects.
Artigo (acupuntura) - Acupuntura e seus riscosRenato Almeida
This review analyzed 57 systematic reviews and 95 case reports regarding acupuncture for pain. The systematic reviews showed inconsistent and contradictory results, with only neck pain having unanimously positive conclusions from high quality reviews. Numerous caveats and contradictions emerged from the reviews. Case reports identified 95 cases of severe adverse effects from acupuncture, including 5 deaths, with pneumothorax and infections being most common. The review concluded that the evidence does not convincingly demonstrate acupuncture is effective for pain relief and that serious adverse effects continue to be reported.
Anxiety and depression affect nearly every other condition and complaint in the body. Overwhelming stress can render conventional treatments useless. Acupuncture can restore balance, reduce the stress response, disrupt the pathways of stress and reduce the effects of overwhelming burdens so that doctors are able to effectively treat even their most difficult cases.
The conundrum of opioid tapering in long term opioid therapy for chronic pain...Paul Coelho, MD
The document discusses the challenges clinicians face when tapering patients off long-term opioid therapy for chronic pain. It explains that opioid dependence can cause worsening pain, psychiatric symptoms, and functioning during tapering due to neuroplastic changes. While tapering seems logical to address risks of high-dose opioids, it may paradoxically make a patient's issues worse due to protracted abstinence syndrome. The document provides guidance for managing these complex patients focused on both pain and opioid dependence.
This randomized controlled trial compared the effectiveness of virtual reality graded exposure therapy (VR-GET) to treatment as usual (TAU) for active duty service members with combat-related post-traumatic stress disorder (PTSD). 19 participants were randomly assigned to either VR-GET (10 participants) or TAU (9 participants). VR-GET consisted of VR exposure combined with skills training, while TAU included various PTSD treatments like prolonged exposure therapy. Results found that 7 of 10 in the VR-GET group improved by at least 30% on the Clinician Administered PTSD Scale, compared to only 1 of 9 in the TAU group, indicating VR-GET was more effective for treating combat-related PTSD.
Effect of homeopathy on chronic tension-type headache: a pragmatic, randomise...home
Homeopathy is increasingly used by headache patients in
general practice but scientific evidence is lacking. We
therefore designed a clinical trial in a way that would not
change the practice pattern of homeopathic physicians.
The document provides a critical analysis of claims made in a 2012 study by Lozano et al regarding the rationale for selecting the subcallosal cingulate gyrus as a target for deep brain stimulation to treat treatment-resistant depression. The analysis finds that the evidence cited by Lozano et al. to support the involvement of the subcallosal cingulate gyrus in processing acute sadness is insufficient. Several of the cited studies do not specifically implicate this brain region or have limitations such as small sample sizes that weaken their conclusions. The analysis concludes the evidence presented is not adequate to definitively support targeting the subcallosal cingulate gyrus with deep brain stimulation.
This randomized clinical trial tested the effectiveness of stellate ganglion block (SGB) treatment compared to a sham procedure for reducing posttraumatic stress disorder (PTSD) symptoms over 8 weeks. 113 active-duty service members with PTSD symptoms were randomly assigned to receive either 2 SGB treatments 2 weeks apart or a sham procedure. The primary outcome was change in PTSD symptom severity scores measured by the CAPS-5 scale from baseline to 8 weeks. Participants receiving SGB had a greater reduction in symptoms scores compared to the sham group, with adjusted mean decreases of 12.6 vs 6.1 points respectively, indicating SGB treatment may help reduce PTSD symptoms.
Primary Headache Associated with Sexual Activity Ade Wijaya
This document defines and discusses primary headache associated with sexual activity (PHASA). It presents that PHASA involves headache brought on by sexual activity, most commonly a dull bilateral pain that increases with excitement and peaks around orgasm. It can last 1 minute to 72 hours. The document outlines that PHASA is diagnosed through exclusion of other causes and can be treated acutely with indomethacin or triptans or prevented with indomethacin, triptans, or beta blockers like propranolol for 2-6 months.
This study surveyed behavioral health clinicians with experience using stellate ganglion block (SGB) as an adjunct treatment for trauma-related disorders like PTSD. Of the 23 respondents, 95% would recommend SGB to colleagues. Respondents rated SGB as at least as useful as the highest rated standard PTSD interventions. SGB was seen as most helpful for reducing arousal/reactivity symptoms. The majority would refer patients for SGB at any stage of therapy, including before starting other treatments.
This document summarizes various interventional treatments for headaches including occipital nerve blocks, pulsed radiofrequency of the occipital nerve, and occipital nerve stimulation. It provides epidemiological data on migraine and cluster headaches. It also discusses indications for occipital nerve blocks including various headache types. Peripheral nerve blocks are described as commonly used but with variable methodology. Effectiveness of occipital nerve stimulation is supported for various intractable headache conditions but lead migration is a technical challenge.
No poison can kill a positive thinker and no medicine can cure a negative thinker. Pain is a complex perceptual experience. Pain is a major public health problem. Beat back pain without surgery and conquer pain without painkillers. Delays have dangerous ends. Knee braces invite injury. Chronic pain affects one in three people in the United States. There are more Americans suffering from chronic pain than with diabetes, heart disease, and cancer combined. Chronic pain is caused by degeneration, illnesses, injuries, surgeries, and treatment side effects. Pain is a major public health problem and is the most common reason why Americans use complementary and integrative health practices. Recent imaging evidence suggests a possible hypothalamic origin for a headache attack, but further research is needed. A migraine is associated with a modest increase in the risk of ischemic stroke.
This document discusses strategies to prevent and manage delirium in critically ill patients. It outlines the ABCDEF bundle which includes assessing, preventing, and managing pain, both spontaneous awakening and breathing trials, minimizing sedation, assessing and preventing delirium, early mobility and exercise, and engaging family members. Screening for delirium using the CAM-ICU tool and implementing non-pharmacological interventions can reduce length of hospital stay, duration of mechanical ventilation, and mortality. Widespread use of protocols and bundles that incorporate these strategies may help address the high cost and poor outcomes associated with delirium.
A single blind RCT to evaluate the effect of intraoperative bupivacaine infilteration fro post operative pain relief was conducted. Observations based on the VAS and mean duration for requirement of 1st analgesic dose post operatively. Results compared with other similar studies and found that the there is significant reduction in the VAS of post operative pain and increase in the duration for requirement for the 1st dose of the analgesic postoperatively
The volume of Big data is increasing in gigabytes day by day which are hard to make sense and difficult to analyze. The challenges of big data are capturing, storing, searching, sharing, analysis and visualization of these datasets. Big data leads to clutter in their visualization. Clutter is a crowded or disordered collection of graphical entities in information visualization. It can blur the structure of data. In this paper, we present the concept of clutter based dimension reduction. Our purpose is to reduce clutter without reducing information content or disturb data in any way. Dimension reduction is a technique that can significantly reduce the dimensions of the datasets. Dimensionality reduction is useful in visualizing data, discovering a compact representation, decreasing computational processing time and addressing the curse of dimensionality of high-dimensional spaces.
In this paper, we provide a detailed description of methodology for deriving and applying Electronic Commerce (EC) security countermeasures design models from the existing IT standards. Our goal is to describe a model-based approach of how to extend such a model or “specialize” it in order to apply it to e-commerce systems.
An important task for a digital communications receiver is to remove any frequency/phase offsets that might exist between the transmitter and receiver oscillators. The use of a Phase Locked Loop enables the receiver to adaptively track and remove frequency/phase offsets. The pll consists of loop filter, VCO and amplifier. The paper describes the designing of this loop filter using CMOS. The use of this element reduces cost drastically and has a good response. An experiment was conducted through this component which provided better result. The main advantage of designing low pass filter by CMOS is that it offers improvements in design simplicity and programmability when compared to op-amp based structures as well as reduced component count. It has high noise immunity and low static power consumption. Hence the overall efficiency increases as well producing the desired effect.
This study compares malt quality parameters of finger millet and sorghum. The quality of malt consequently affects the quality of opaque beer produced. Certain parameters are analyzed before the malt is accepted for beer brewing. Grain samples of finger millet and sorghum were tested for germination energy before malting. The resultant malts were analyzed for moisture, diastatic power and free amino nitrogen. Finger millet achieved 100% germination while sorghum attained 99% germination in 3 days. After 5 days malting finger millet had higher moisture content (44%) than sorghum (48%). In terms of free amino nitrogen, finger millet had an average of 114.3 mg/L whilst sorghum had an average of 138.6 mg/L. Diastatic power for finger millet malt was lower (13.6 SDU/g) than that of sorghum malt (30.3 SDU/g). Finger millet has demonstrated a great potential to be used in the brewing of commercial opaque beer.
Biceps brachii is stated as one of the muscles that shows most frequent anatomical variations. Its most commonly reported anomaly is the presence of a third head arising from the humerus which is termed as Caput Accessorium ,therefore, detailed knowledge of this variation in different populations is important for surgical interventions of the arm, nerve compression syndromes and in unexplained pain syndromes in the arm or shoulder region. The goal of this study was to elucidate the incidence of this muscle in an adult U.P west population. Upper extremities of the total of 50 cadavers were dissected and studied for the presence of accessory heads of the biceps brachii muscle. The incidence of humeral head of biceps brachii was found to be 6%. In all cases, it was found unilaterally and only in male subjects. Knowledge of the occurrence of humeral head of biceps brachii may facilitate preoperative diagnosis as well as the surgical procedures of the upper limb thus avoiding iatrogenic injuries.
This document discusses various techniques for hiding secret information in digital video files for secure communication, known as video steganography. It begins by explaining steganography and comparing it to cryptography. It then discusses different video steganography methods, including least significant bit and spread spectrum approaches. It also covers combining steganography with encryption algorithms like AES. Previous research on video steganography is summarized, focusing on techniques that embed data in wavelet coefficients or motion vectors. The document concludes that further research could explore hiding moving images within video files using steganography and cryptography methods.
Chronic daily headache is a debilitating condition affecting millions in the US. It involves headaches occurring more than 15 days per month for over 3 months. The document discusses the diagnosis and management of chronic daily headache. Key points include distinguishing between primary headache disorders like migraine from secondary disorders caused by other conditions. Treatment involves identifying medication overuse, treating any comorbid conditions, using preventive medications, and limiting the use of rescue medications to no more than 2 times per week to prevent rebound headaches.
To adjust oneself in modern scientific world, and to understand an environment in which industrial technology and science play an ever more important role, man needs a solid grounding in science. The initial scientific knowledge he has given in the course of regular schooling is no longer enough. From the point of view both of knowledge and of methods, the education must continue throughout his working life. Education is a lifelong process. The growing need for scientific knowledge and training, due to the evaluation of the modern world and the rapid spread of education, has been analysed and is now widely recognized. In face of that need, it would seem logical to give emphasis on the most modern educational technologies, and in particular, to make a wide spread mass use of television techniques, internet, multimedia etc. This study investigated the impact of information and communication technology (ICT) on Achievement of Students in Chemistry at Secondary Level. For the purpose, a list of secondary school of CBSE and U.P. Board are prepared and four institutions were selected with the help of lottery method. The selected samples of four schools were randomly divided into two groups Experimental groups and Controlled groups. The required data was collected at two stages as pre-test and post test scores from the achievement test in chemistry. Data was analysed quantitatively employing statistical techniques of mean, S.D. and t-test.
This document provides information on various primary and secondary headache types including their characteristics, differential diagnoses, and treatment approaches. It discusses tension-type headache, trigeminal autonomic cephalalgias including cluster headache, paroxysmal hemicrania and SUNCT/SUNA. It also summarizes chronic daily headache, other primary headaches such as chronic post-traumatic headache, hypnic headache and medication overuse headache.
A small H-shaped microstrip patch antenna (MPA) with enhanced bandwidth is presented. The H-shaped antenna is first studied and then fully simulated by HFSS. A dual U slot H patch configuration is proposed to increase the narrow bandwidth, radiation efficiency and directivity. A novel H-shaped patch antenna suitable for wireless and satellite communications is presented. This paper presents the dual U slot H-shaped microstrip patch antenna feed by transmission line. The decrease in the prices of handheld devices and services has made available on the move internet and web services facility to the customers, small antennas requirement are increasing. In this paper H-shaped patch antenna is designed using FR4 substrate. The proposed modified H shaped antenna is designed and simulated using HFSS and caters to various wireless applications such as WiMAX, Wi-Fi, UMTS and Digital Multimedia Broadcasting (DMB) e.g. T V, etc.
The document outlines the classification of headaches according to the International Headache Society. It discusses the primary and secondary headaches, listing the specific types under each category. For the primary headaches, it describes the characteristics of migraine, tension-type headache, and cluster headaches. It also discusses the symptoms, locations, intensities, modes of onset and durations of different headache types to help with diagnosis. The document provides details on pain-sensitive and insensitive cranial structures and the pathways involved in headache pain. It explains the concept of referred pain from structures innervated by the trigeminal, cervical and other cranial nerves.
Headache diagnostc paradigm from former Johns Hopkins Hospital staffNelson Hendler
The medical literature reports that 35%-70% of patients diagnosed with migraine headache do not have this order. The Internet based "expert system" developed by former Johns Hopkins Hospital staff, including the past president of the American Headache Society and American Academy of Pain Management provides an Internet based "expert system" which gives diagnoses with a 94% correlation with diagnosed of these doctors.
1) The study investigated using non-painful electrical stimulation of the skin on the arm to reduce migraine attacks. It found that nearly 2/3 of patients experienced at least a 50% reduction in pain, especially when used early in an attack.
2) 86 patients with a history of migraines participated in the study. They were divided into groups that received real or sham stimulation to the arm.
3) While the study supports using non-invasive arm stimulation to reduce migraine pain, its effectiveness for more frequent or severe migraines, or those taking preventative medications, remains unknown.
This document provides information on common primary headaches including migraine, tension-type headache, and cluster headache. It discusses prevalence, diagnostic criteria, pathophysiology, comorbidities, and treatment approaches for each headache type. For migraine specifically, it notes higher prevalence in women ages 25-55 and common comorbidities like depression and anxiety. Treatment involves both acute and preventive options.
The document provides information about headaches including:
1) Headaches are classified as primary, secondary, or other types based on their cause.
2) Tension headaches are the most common primary headache, often caused by muscle tension.
3) Secondary headaches have an underlying medical cause like injury or illness.
Diagnosis and Management of Chronic pain associated with depression.pptxssuser40df77
Chronic pain and depression are often comorbid conditions that can mutually exacerbate one another through shared neural pathways and neuroplasticity changes in the brain. Approximately half of patients with depression report chronic pain, while 30-60% of individuals with chronic pain meet criteria for depression. Regions implicated in both chronic pain processing and mood regulation include the insular cortex, prefrontal cortex, anterior cingulate, thalamus, hippocampus and amygdala. Greater functional connectivity between the nucleus accumbens and prefrontal cortex in patients with sub-acute back pain has been found to predict transition to chronic pain. Effective treatment of depression may help alleviate chronic pain.
This document summarizes key information about nummular headache from published case studies and literature. It begins with a case study of a 55-year-old man experiencing focal, severe head pain in his left occipital region within a perfectly circular area. It then reviews diagnostic criteria requiring mild to moderate head pain within a rounded or elliptical area, and discusses epidemiology, clinical features and treatment based on 60 identified case reports, noting it is more common in women aged 40-50 and usually presents as unilateral pain within the parietal region.
This document provides guidelines from the British Association for the Study of Headache for the diagnosis and management of common headache disorders. It covers migraine, tension-type headache, cluster headache, and medication-overuse headache. The guidelines are intended for all healthcare professionals and recommend a flexible, individualized approach to diagnosis and treatment. Key aspects addressed include headache classification, taking a patient history, diagnosing specific headache types, differential diagnosis, physical examination, and potential investigations.
The document provides an overview of headaches and headache disorders. It begins by classifying headaches into primary and secondary types according to the International Classification of Headache Disorders. Tension-type headache is discussed in more detail, including its clinical features, diagnostic criteria, prevalence, pathophysiology, treatment options including pharmacological and non-pharmacological approaches, and its high rates of comorbidity with mental health conditions like depression and anxiety. The document emphasizes screening headache patients for psychiatric symptoms.
This document provides a summary of headache types including definitions, epidemiology, causes, evaluation, diagnosis, and management. It discusses common primary headache disorders like migraine and tension-type headache as well as secondary headaches that can be caused by conditions like sinusitis, pseudotumor cerebri, trigeminal neuralgia, and temporal arteritis. Key details are provided on symptoms, risk factors, diagnostic criteria and tests, and treatment approaches for each headache type. The document aims to educate medical students on conducting thorough evaluations and making accurate diagnoses to appropriately manage patients presenting with headaches.
The document provides information about headaches and treatment options available at Shands Neuroscience Institute in Jacksonville, Florida. It states that headaches are the most common reason patients see a doctor, with 6% of men and 18% of women in the US suffering from headaches. Physicians at Shands specialize in treatments to reduce headache frequency, severity, and disability, and improve quality of life. The document describes different types of headaches including migraines, cluster headaches, tension headaches, and sinus headaches. It provides information on headache prevention strategies like identifying triggers, keeping a journal, diet, limiting caffeine and alcohol, and relaxing. Treatment options discussed include medication management, pain management therapies, Botox therapy, and dietary consultations.
This study evaluated 70 patients with chronic migraine to assess the severity and clinical features of depression. The Beck Depression Inventory (BDI) scores ranged from 4 to 55, with a mean of 21, indicating moderate to severe depression in 58.7% of patients and some degree of depression in 85.8% of patients. Patients with fibromyalgia or fatigue were more likely to have severe depression. The BDI proved an effective tool for assessing depression in chronic migraine patients. Recognition of depression and suicide risk is important in managing chronic migraine.
This document discusses chronic daily headache (CDH), defined as a headache occurring on 15 or more days per month for more than 3 months. It describes the classification of primary and secondary CDH according to the International Headache Society. Primary CDH includes chronic migraine, chronic tension-type headache, new daily persistent headache, and hemicrania continua. Secondary CDH is caused by underlying head/neck issues, vascular disorders, infections, or psychiatric disorders. Risk factors, pathophysiology, treatment approaches including medication overuse management, and lifestyle modifications are summarized.
- Approximately half of adults worldwide suffer from headache disorders. The International Headache Society classification helps doctors differentiate primary headaches from secondary headaches caused by underlying conditions.
- A thorough history and physical exam, focusing on features of primary headaches, can often determine the headache type and reduce unnecessary tests.
- The document provides diagnostic criteria and recommendations for evaluating and testing various headache types like migraines, tension headaches, and cluster headaches. Danger signs require further investigation through tests like neuroimaging, lumbar puncture, or blood tests to rule out secondary causes.
—Pain following Spinal Cord Injury (SCI) is very common. So this study was conducted to find out prevalence, associated factors and pattern of Neuropathic Pain (NP) among SCI patients, for which 494 consecutive eligible patients of Spinal Cord Injury (SCI) admitted in the Department were evaluated for NP. It was observed that 13.76% of SCI patients complained of neuropathic pain. In 21 to 30 years age group 23.13% and 61.76% cases of neuropathic pain had dorso-lumbar injury. 48.30% cases of neuropathic pain had onset in 2 nd and 3 rd week. Discomfort was more at night (36.76%), in below the knee area and dorsum of the foot. Hot burning type of sensation was the commonest descriptor of NP and range of movement (ROM) exercises and tepid cold water sponging were relieving factors.
Pain as the 5 th vital sign guidelines for doctorsterezacl
This document provides guidelines for doctors on the management of adult patients' pain. It includes 5 guidelines and 2 appendices. Guideline 1 discusses pain assessment. Guideline 2 differentiates between acute and chronic pain. Guideline 3 provides a general guide for managing chronic non-cancer pain. Guideline 4 presents an analgesic ladder for acute pain management. Guideline 5 describes a morphine pain protocol for rapid pain relief through opioid titration. The appendices provide notes on analgesic medications and management of side effects. The guidelines aim to help doctors properly assess, diagnose, and treat patients' acute and chronic pain.
Headache is classified mainly into two categories: Primary and secondary.
Primary headache is usually benign and longstanding. Common primary headaches are migraine and tension type headache. They have typical features – Migraine, tends to be pulsating in character, affecting one side of the head, associated with nausea, disabling in severity and it usually lasts between 3 hours and 3 days.
Similar to Clinical profiles in Patients Suffering from Chronic Tension-type Headache (20)
"Heart failure is a typical clinical accompanied by symptoms syndrome (e.g. shortness of breath, ankle swelling and fatigue) that lead to structural or functional abnormalities of the heart (e.g. high venous pressure, pulmonary edema and peripheral edema).
In recent years, the significant role of B-type natriuretic peptide has been revealed in the pathogenesis of heart disease and the use of the drug sacubitril/valsartan has started. It has a positive effect on the regulation of the level of B-type natriuretic peptide in the body. It is obviously seen from the the world literature that natriuretic peptides play an important role in the pathophysiology of heart failure. For this reason, many studies suggest that the importance of natriuretic peptides in the diagnosis and treatment of heart failure is recommended.
Due to this, we tried to investigate the effects of a comprehensive medication therapy with a combination of sacubitril/valsartan in the patients with chronic heart failure."
This document describes the design and implementation of a carrier-based sinusoidal pulse width modulation (SPWM) bipolar inverter. It begins with an introduction to inverters that convert DC power to AC power. It then discusses SPWM techniques in detail, including bipolar and unipolar switching methods. The document presents simulation results for a single-phase inverter using SPWM strategies. It aims to simulate and analyze the output waveforms of a SPWM inverter model in MATLAB, and examine how the modulation index affects the simulated and implemented designs.
This document analyzes the polarization and transmission effects of antireflection coatings for silicon-on-insulator (SOI) material systems using simulation software. Without a coating, transmission of transverse magnetic (TM) polarized light is slightly higher than transverse electric (TE) polarized light. A single-layer antireflection coating is designed and optimized to increase average transmission by 19%, reducing the polarization effect. However, multilayer coatings did not further increase transmission over the optimized single layer. In conclusion, antireflection coatings can effectively reduce polarization dependence for SOI materials while improving overall light transmission.
This document proposes a new method called multi-surface fitting for enhancing the resolution of digital images. The method fits multiple surfaces, with one surface fitted for each low-resolution pixel, and then fuses the multi-sampling values from these surfaces using maximum a posteriori estimation. This allows more low-resolution pixel information to be utilized to reconstruct the high-resolution image compared to other interpolation-based methods. The method is shown to effectively preserve image details without requiring assumptions about the image prior, as iterative techniques do. It provides error-free high resolution for test images.
The document discusses technical issues related to radio links, security, and quality of service (QoS) in mobile ad hoc networks (MANETs). MANETs are self-organized, decentralized networks formed by wireless mobile nodes without a fixed infrastructure. Key challenges in MANETs include limited wireless transmission range, dynamic changes in network topology, interference, and energy constraints of battery-powered devices. The document outlines various characteristics of MANETs, including that they are self-configuring, infrastructureless networks that enable communication in situations where fixed networks are unavailable or inadequate.
This document summarizes a study that investigated applying a stainless steel spray coating called SS-II to an LM13 aluminum alloy used in engine applications. The study aimed to reduce surface roughness and friction of reciprocating engine parts. Key findings include:
1) Surface roughness and hardness tests found that applying the SS-II coating maintained surface roughness while increasing hardness.
2) Pin-on-disk friction tests found that the SS-II coating reduced the coefficient of friction at different speeds compared to uncoated LM13 alloy.
3) Scanning electron microscope images showed the SS-II coating had low porosity and good adhesion to the LM13 substrate, as well as evidence of wear on coated samples tested.
This document provides an overview of aluminum metal matrix composites with hybrid reinforcement. It discusses how aluminum alloys combine desirable properties of metals and ceramics when reinforced particles are added to the metal matrix. The document reviews the advantages of aluminum, such as its light weight, corrosion resistance, and recyclability. It also discusses aluminum alloy types and applications, as well as desirable mechanical properties for metal composites like tensile strength and yield point. The aim is to initiate new research on developing aluminum composites with hybrid reinforcements.
This document describes a study on using silver nanoparticles incorporated onto polyurethane foam to mineralize pesticides in water. Silver nanoparticles were synthesized using trisodium citrate and characterized before being incorporated onto polyurethane foam. The foam was then used to mineralize chlorpyrifos and malathion in water solutions at different concentrations over time. Mineralization time was found to increase with higher initial pesticide concentration, with chlorpyrifos being fully mineralized faster than malathion at the same concentrations. The study evaluated silver nanoparticles on polyurethane foam as a potential method for removing pesticides from contaminated water.
This document provides a comparative study of computers operated by eyes and brain. It discusses the techniques used for eye tracking in computers operated by eyes, including electro-oculography and pupil tracking. Advantages include ability for disabled people to use computers, while disadvantages include need for head stability and training. Computers operated by brain use EEG to detect brain signals via electrodes on the scalp. Signals are interpreted as commands. Advantages are independence from movement and location, while disadvantages include risks of surgery and interference with signals. Key differences between the two methods are also summarized.
This document discusses T.S. Eliot's concept of literary tradition and the importance of allusions. Eliot believed that tradition is not just inheriting the past, but achieving a historical sense that perceives the past as both past and present. An artist must have a strong background in their cultural and literary history. Eliot argued that when a new work is allusive to past works, it positively affects the whole literature of a country. The use of allusions is an important way for authors to maintain literary tradition by referencing ideas from previous works. The document provides details on Eliot's views and analyzes how later critics interpreted and applied his concept of the historical sense.
This document discusses load balancing strategies for grid computing. It proposes a dynamic tree-based model to represent grid architecture in a hierarchical way that supports heterogeneity and scalability. It then develops a hierarchical load balancing strategy and algorithms based on neighborhood properties to decrease communication overhead. Conventional scheduling algorithms like Min-Min, Max-Min, and Sufferage are discussed but determined to ignore dynamic network status, which is important for load balancing. Genetic algorithms are also mentioned as a potential solution.
This document proposes a new zone-based bandwidth allocation protocol for wireless networks. The key points are:
1. It divides the network into zones based on hop count from the initial relay station, and allocates bandwidth to each zone to improve quality of service.
2. Within each zone, the bandwidth allocated is distributed to mobile users based on their visiting probability and required bandwidth. This aims to maximize the average user satisfaction rate.
3. The protocol is evaluated through simulations using the Network Simulator 2 (NS2) tool. Results show the protocol improves bandwidth allocation efficiency and reduces quality of service degradation compared to other approaches.
- The burning of fossil fuels like coal, oil, and gas releases carbon dioxide into the atmosphere, which acts as a greenhouse gas and traps heat. This is the main human activity contributing to global climate change.
- As carbon dioxide levels in the atmosphere increase due to fossil fuel burning, more heat gets trapped leading to a rise in average global temperatures, a phenomenon known as global warming.
- Climate change has both natural and human-caused factors. Natural causes include changes in the Earth's orbit and solar activity, while the dominant human cause is burning fossil fuels which releases carbon dioxide and other greenhouse gases into the atmosphere.
This document summarizes research assessing the performance of control loops using a minimum variance control algorithm (FCOR) and comparing it to an existing algorithm (PINDEX). The researchers implemented both algorithms in MATLAB to analyze simulated process data from MATLAB/Simulink models with and without valve stiction. They also analyzed process data from an Aspen HYSIS simulation of a distillation column. Across all the simulations and models, the FCOR and PINDEX algorithms produced generally similar results, indicating the control loops were performing poorly in cases where the performance index values were close to 0. The research thus validated that the developed FCOR algorithm worked effectively to evaluate control loop performance based on minimum variance.
This document provides an overview of the capital market in Bangladesh. It discusses how capital markets can contribute significantly to a country's GDP and economic strength. However, Bangladesh's capital market, especially its share market, has not played as large a role as expected compared to other regional countries. The document suggests that the government and regulatory authorities need to take a more active role in strengthening the capital market to boost investor and issuer confidence and participation. It analyzes issues currently hindering the effectiveness and growth of Bangladesh's capital market.
This document discusses techniques for improving the speed of web crawling through parallelization using multi-core processors. It provides background on how web crawlers work as part of search engines to index web pages. Traditional single-core crawlers can be improved by developing parallel crawlers that distribute the work of downloading, parsing, and indexing pages across multiple processor cores. This allows different parts of the crawling process to be performed simultaneously, improving overall speed. The document reviews several existing approaches for distributed and parallel web crawling and proposes using a multi-core approach to enhance crawling speed and CPU utilization.
This document describes an extended fuzzy c-means (EFCM) clustering algorithm for noisy image segmentation. The algorithm first preprocesses noisy pixels in an image by regenerating their values based on neighboring pixel intensities. It then applies the conventional fuzzy c-means clustering algorithm to segment the image. The EFCM approach is presented as being less sensitive to noise than other clustering algorithms and able to efficiently segment noisy images. The document provides background on image segmentation, fuzzy c-means clustering, types of image noise, and density-based clustering challenges. It also outlines the EFCM methodology and its computational advantages over other robust clustering methods for noisy image segmentation.
This document discusses parallel algorithms for generating pseudo-random numbers using classical congruent methods. Algebraic and matrix interpretations are presented for realizing the algorithms in parallel. The key congruent methods - formulas (1) through (4) - are expressed algebraically and transformed into parallel forms involving matrices or sequences of numbers. Examples are given applying the parallel forms to generate sequences of pseudo-random numbers modulo a large prime number. Ensuring reliable parallel generation through error control is the goal.
More from International Journal of Science and Research (IJSR) (20)
Leveraging Generative AI to Drive Nonprofit InnovationTechSoup
In this webinar, participants learned how to utilize Generative AI to streamline operations and elevate member engagement. Amazon Web Service experts provided a customer specific use cases and dived into low/no-code tools that are quick and easy to deploy through Amazon Web Service (AWS.)
Chapter wise All Notes of First year Basic Civil Engineering.pptxDenish Jangid
Chapter wise All Notes of First year Basic Civil Engineering
Syllabus
Chapter-1
Introduction to objective, scope and outcome the subject
Chapter 2
Introduction: Scope and Specialization of Civil Engineering, Role of civil Engineer in Society, Impact of infrastructural development on economy of country.
Chapter 3
Surveying: Object Principles & Types of Surveying; Site Plans, Plans & Maps; Scales & Unit of different Measurements.
Linear Measurements: Instruments used. Linear Measurement by Tape, Ranging out Survey Lines and overcoming Obstructions; Measurements on sloping ground; Tape corrections, conventional symbols. Angular Measurements: Instruments used; Introduction to Compass Surveying, Bearings and Longitude & Latitude of a Line, Introduction to total station.
Levelling: Instrument used Object of levelling, Methods of levelling in brief, and Contour maps.
Chapter 4
Buildings: Selection of site for Buildings, Layout of Building Plan, Types of buildings, Plinth area, carpet area, floor space index, Introduction to building byelaws, concept of sun light & ventilation. Components of Buildings & their functions, Basic concept of R.C.C., Introduction to types of foundation
Chapter 5
Transportation: Introduction to Transportation Engineering; Traffic and Road Safety: Types and Characteristics of Various Modes of Transportation; Various Road Traffic Signs, Causes of Accidents and Road Safety Measures.
Chapter 6
Environmental Engineering: Environmental Pollution, Environmental Acts and Regulations, Functional Concepts of Ecology, Basics of Species, Biodiversity, Ecosystem, Hydrological Cycle; Chemical Cycles: Carbon, Nitrogen & Phosphorus; Energy Flow in Ecosystems.
Water Pollution: Water Quality standards, Introduction to Treatment & Disposal of Waste Water. Reuse and Saving of Water, Rain Water Harvesting. Solid Waste Management: Classification of Solid Waste, Collection, Transportation and Disposal of Solid. Recycling of Solid Waste: Energy Recovery, Sanitary Landfill, On-Site Sanitation. Air & Noise Pollution: Primary and Secondary air pollutants, Harmful effects of Air Pollution, Control of Air Pollution. . Noise Pollution Harmful Effects of noise pollution, control of noise pollution, Global warming & Climate Change, Ozone depletion, Greenhouse effect
Text Books:
1. Palancharmy, Basic Civil Engineering, McGraw Hill publishers.
2. Satheesh Gopi, Basic Civil Engineering, Pearson Publishers.
3. Ketki Rangwala Dalal, Essentials of Civil Engineering, Charotar Publishing House.
4. BCP, Surveying volume 1
हिंदी वर्णमाला पीपीटी, hindi alphabet PPT presentation, hindi varnamala PPT, Hindi Varnamala pdf, हिंदी स्वर, हिंदी व्यंजन, sikhiye hindi varnmala, dr. mulla adam ali, hindi language and literature, hindi alphabet with drawing, hindi alphabet pdf, hindi varnamala for childrens, hindi language, hindi varnamala practice for kids, https://www.drmullaadamali.com
Main Java[All of the Base Concepts}.docxadhitya5119
This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
Gender and Mental Health - Counselling and Family Therapy Applications and In...PsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...PECB
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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Philippine Edukasyong Pantahanan at Pangkabuhayan (EPP) CurriculumMJDuyan
(𝐓𝐋𝐄 𝟏𝟎𝟎) (𝐋𝐞𝐬𝐬𝐨𝐧 𝟏)-𝐏𝐫𝐞𝐥𝐢𝐦𝐬
𝐃𝐢𝐬𝐜𝐮𝐬𝐬 𝐭𝐡𝐞 𝐄𝐏𝐏 𝐂𝐮𝐫𝐫𝐢𝐜𝐮𝐥𝐮𝐦 𝐢𝐧 𝐭𝐡𝐞 𝐏𝐡𝐢𝐥𝐢𝐩𝐩𝐢𝐧𝐞𝐬:
- Understand the goals and objectives of the Edukasyong Pantahanan at Pangkabuhayan (EPP) curriculum, recognizing its importance in fostering practical life skills and values among students. Students will also be able to identify the key components and subjects covered, such as agriculture, home economics, industrial arts, and information and communication technology.
𝐄𝐱𝐩𝐥𝐚𝐢𝐧 𝐭𝐡𝐞 𝐍𝐚𝐭𝐮𝐫𝐞 𝐚𝐧𝐝 𝐒𝐜𝐨𝐩𝐞 𝐨𝐟 𝐚𝐧 𝐄𝐧𝐭𝐫𝐞𝐩𝐫𝐞𝐧𝐞𝐮𝐫:
-Define entrepreneurship, distinguishing it from general business activities by emphasizing its focus on innovation, risk-taking, and value creation. Students will describe the characteristics and traits of successful entrepreneurs, including their roles and responsibilities, and discuss the broader economic and social impacts of entrepreneurial activities on both local and global scales.
Temple of Asclepius in Thrace. Excavation resultsKrassimira Luka
The temple and the sanctuary around were dedicated to Asklepios Zmidrenus. This name has been known since 1875 when an inscription dedicated to him was discovered in Rome. The inscription is dated in 227 AD and was left by soldiers originating from the city of Philippopolis (modern Plovdiv).
This document provides an overview of wound healing, its functions, stages, mechanisms, factors affecting it, and complications.
A wound is a break in the integrity of the skin or tissues, which may be associated with disruption of the structure and function.
Healing is the body’s response to injury in an attempt to restore normal structure and functions.
Healing can occur in two ways: Regeneration and Repair
There are 4 phases of wound healing: hemostasis, inflammation, proliferation, and remodeling. This document also describes the mechanism of wound healing. Factors that affect healing include infection, uncontrolled diabetes, poor nutrition, age, anemia, the presence of foreign bodies, etc.
Complications of wound healing like infection, hyperpigmentation of scar, contractures, and keloid formation.
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
আমাদের সবার জন্য খুব খুব গুরুত্বপূর্ণ একটি বই ..বিসিএস, ব্যাংক, ইউনিভার্সিটি ভর্তি ও যে কোন প্রতিযোগিতা মূলক পরীক্ষার জন্য এর খুব ইম্পরট্যান্ট একটি বিষয় ...তাছাড়া বাংলাদেশের সাম্প্রতিক যে কোন ডাটা বা তথ্য এই বইতে পাবেন ...
তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UPRAHUL
This Dissertation explores the particular circumstances of Mirzapur, a region located in the
core of India. Mirzapur, with its varied terrains and abundant biodiversity, offers an optimal
environment for investigating the changes in vegetation cover dynamics. Our study utilizes
advanced technologies such as GIS (Geographic Information Systems) and Remote sensing to
analyze the transformations that have taken place over the course of a decade.
The complex relationship between human activities and the environment has been the focus
of extensive research and worry. As the global community grapples with swift urbanization,
population expansion, and economic progress, the effects on natural ecosystems are becoming
more evident. A crucial element of this impact is the alteration of vegetation cover, which plays a
significant role in maintaining the ecological equilibrium of our planet.Land serves as the foundation for all human activities and provides the necessary materials for
these activities. As the most crucial natural resource, its utilization by humans results in different
'Land uses,' which are determined by both human activities and the physical characteristics of the
land.
The utilization of land is impacted by human needs and environmental factors. In countries
like India, rapid population growth and the emphasis on extensive resource exploitation can lead
to significant land degradation, adversely affecting the region's land cover.
Therefore, human intervention has significantly influenced land use patterns over many
centuries, evolving its structure over time and space. In the present era, these changes have
accelerated due to factors such as agriculture and urbanization. Information regarding land use and
cover is essential for various planning and management tasks related to the Earth's surface,
providing crucial environmental data for scientific, resource management, policy purposes, and
diverse human activities.
Accurate understanding of land use and cover is imperative for the development planning
of any area. Consequently, a wide range of professionals, including earth system scientists, land
and water managers, and urban planners, are interested in obtaining data on land use and cover
changes, conversion trends, and other related patterns. The spatial dimensions of land use and
cover support policymakers and scientists in making well-informed decisions, as alterations in
these patterns indicate shifts in economic and social conditions. Monitoring such changes with the
help of Advanced technologies like Remote Sensing and Geographic Information Systems is
crucial for coordinated efforts across different administrative levels. Advanced technologies like
Remote Sensing and Geographic Information Systems
9
Changes in vegetation cover refer to variations in the distribution, composition, and overall
structure of plant communities across different temporal and spatial scales. These changes can
occur natural.
Clinical profiles in Patients Suffering from Chronic Tension-type Headache
1. International Journal of Science and Research (IJSR), India Online ISSN: 2319-7064
Volume 2 Issue 9, September 2013
www.ijsr.net
Clinical profiles in Patients Suffering from Chronic
Tension-type Headache
Rajamani Santhosh Kumar 1
, K. Rathna Kumar2
1
Assistant Professor of ENT Head and Neck surgery (Principle author)
Sri Lakshmi Narayana Institute of Medical Sciences, Osudu, Kudapakkam, Puducherry State, PIN 605 502, India
2
Associate Professor of Ophthalmology (Second author)
Sri Lakshmi Narayana Institute of Medical Sciences, Osudu, Kudapakkam, Puducherry State, PIN 605 502, India
Abstract: Chronic Tension-type headache is the most common type of headache encountered in clinical setup. This study aims to
examine the clinical profile of patients suffering from chronic Tension-type headache.
Keywords: Tension-type headache, Chronic headache, Episodic headache, Daily headache
1. Introduction
Tension type headache is the most common type of headache
seen in E.N.T headache clinic. This condition is particularly
common in multiparous females, has been dubbed the
“House-wife’s headache”. The persistent day-today nature of
this headache has bestowed, the name “Daily headache” to
this condition [1]. This study aims to study the clinical
profile of patients suffering from the chronic variant of
Tension-type headache, which is arbitrarily defined as
Tension-type headache for more than 180 days in a year
2. Materials and Method
Patients were chosen from the subset of cases who attend our
E.N.T headache clinic. We have a specialized O.P.D for
diagnosis and management of Headache held on Tuesdays
and Thursdays. Due consent was obtained from all cases and
hospital and departmental ethical committee approval was
obtained before the initiation of the study.
3. Diagnostic Inclusion Criteria
A total of 50 patients were chosen from the Headache clinic
for this study. The diagnostic criteria for Chronic Tension
type headache used in this study was as follows.
3.1. At least 10 episodes per year, Headaches lasting more
than 180 days in a year [2] or than 15 days a month(Ref 1
and 6)
.
3.2. Bilateral headache, pain compressive in nature mild to
moderate intensity localized to forehead. Pain intensity
varies from attack to attack, with each attack lasting
from minutes to hours.
3.3. Neck pain and rigidity of neck muscles [1, 6]
3. 4. A “Band” like constricting type of frontal pain was
considered diagnostic [4]. Typically, the pain increases
as the day progresses [5]. Presence of Depressive
symptoms and any history of Psychiatric problems are a
part of Tension type headache, hence were not excluded
(Ref 4)
. Emotional stress was enquired as it is a known
trigger for Tension type headache. Day today work and
exertion does not increase the intensity of Chronic
Tension-type headache [7].
3.5. General, E.N.T and neurologic examination is normal
[2]. Blood pressure was checked to ensure normalcy, as
Hypertension can by itself lead to Headache.
Ophthalmological evaluation of Fundus and Visual
fields was done to rule out Papilloedema and Brain
tumors.
3.6. Pericranial Tenderness [6]
This is one of the clinical diagnostic test for Tension type
headache. Palpation for the Pericranial Tenderness
involves using two fingers to palpate the Frontalis,
Temporalis, Masseter, Pterygoid, Sternomastiod and
Trapezius muscles. This is included in second revision
of International Classification of Headache disorders
[6].
4. Diagnostic Exclusion criteria
4.1. Unilateral headache are suggestive of Migraine and
related disorders were excluded [1]
4.2. Nausea, vomiting, photophobia, Aura are suggestive of
Migraine were excluded [2].
4.3. Medication rebound headache is a distinct entity, with a
picture similar to chronic tension type-headache.
Subjects with a history of self administration of drugs,
and use of over the counter pain killers for more than 3
months were not included in this study [8]
5. Type of Study
This was a type of Cross sectional descriptive
epidemiological clinical study.
5.1 Methodology of study
The subjects who attended our Headache clinic were
enquired about their willingness to participate in our study.
After obtaining their consent they were given a questionnaire
based on International Classification of Headache
Disorders—2nd
edition criteria (Ref 6)
. Their response to
various test items, classified and tabulated and presented in
the results as follows.
Paper ID: 12013140 150
2. International Journal of Science and Research (IJSR), India Online ISSN: 2319-7064
Volume 2 Issue 9, September 2013
www.ijsr.net
6. Observations
6.1 Sex wise distribution
Majority of Chronic Tension-type headache headaches are
females (33/50) and Male to female ratio in our study was
found to be 2:1 (= 33/17). This means that Tension-type
headache is twice as more common in females than in males.
6.2 Average age of onset
Based on the questionnaire, Age of onset of headache was
determined for the 50 patients and is summarized in the
following graph.
Figure 1: Age wise distribution of cases. This shows that
most common age of onset is 20to 30 years. Chronic tension
type headache is rare in extremes of age.
As it can be inferred from above, that the most common age
of onset of Chronic Tension-type headache is early
adulthood (20 -30 years) and Middle ages (30 to 50 years).
Onset of this condition seems to be rare in extremes of ages.
6.3 Number of years of suffering
Chronic tension-type headache is a long standing condition
that last for years and even decades. The following graph
was drawn after feeding the data into the PAST statistical
software package, it depicts the number of years of suffering.
Figure 2: Number of years versus number of subjects.
Chronic Tension type headache patients suffer from
headache lasting an average of 2.2 years in duration.
Overlaid on the background is the Normal curve.
The mean number of years of suffering was found to be 2.2
years (2 years 2 months 12 days). The standard deviation
was found to be 2.7, standard error was found to be 0.38.
6.4 Quantification of Pain
A Visual Analogue scale (VAS) was used to quantify the
intensity of pain from 0 to 10. The patients were asked to
quantify the intensity of pain experienced during most of the
episodes. The score of 0 represented no pain and 10 the
worst pain they could imagine. This 0 to 10 VAS modelled
after the pattern in similar studies on chronic headache. The
patient reporting of pain is depicted below.
Figure 3: The intensity of pain on a visual Analogue scale as
perceived by the patients. Majority of the patient reported
the intensity on scale 6/10 as seen from graph. This classical
picture of any Chronic pain.
6.5 Pericranial tenderness
Almost all the patients who participated in this study gave
positive reponse to pericranial tenderness test (47 positive
/50 cases = 94% of cases). This is a very important
diagnostic clinical sign of Chronic tension type headache.
Figure 4: Pericranial tenderness was found in 94% (47/50)
of the cases.
7. Discussion
The chronic subtype is of a more problematic entity, which
is the cause of severe disability in sufferers and also leads to
social stress. Pericranial tenderness is listed as a diagnostic
finding in The International Classification of Headache
Disorders, 2nd
edition. Central pain perception mechanism
Paper ID: 12013140 151
3. International Journal of Science and Research (IJSR), India Online ISSN: 2319-7064
Volume 2 Issue 9, September 2013
www.ijsr.net
seems to play a pivotal role in chronic tension-type headache
(Ref 6 and 11)
.
A “Band” like constricting type of pain, with a feeling of
heaviness is again a hall mark feature of this condition. The
following figure illustrates this.
Figure 5: The hallmark, “Band” like bilateral pain over the
scalp along with a feeling of heaviness over the head of
Tension type headache. This is accompanied by the
Pericranial muscle tenderness on palpation.
Most of the patients had the onset of the headache in their
20s and 30s, which was persistent; the average duration of
suffering for a patient was 2.2 years. This was elucidated
from our study. Day today work and exertion does not
increase the intensity of Chronic Tension-type headache [7].
Majority of the patient reported the intensity on scale 6/10 as
seen from above graph. In addition, varying intensity of pain
is a classical symptom of tension- type headache, and pain is
never severe in Intensity. This is the intensity represented by
the grades 4,5,6,7 in the VAS scale used in our study and is
illustrated in the cartoon picture that follows.
Figure 6: Varying intensity of pain “band” in Tension type
headache, with mild pain patient can carry out his day today
activities (Shown by smiling face). Days when he has severe
pain can be incapacitating (Shown by sad face). Patients can
go on for months with suffering.
Chronic migraine in which the sufferer has pain for more
than 15 days in month is a differential diagnosis of this
condition. But migrainous headache is more severe,
unilateral and associated with nausea and photophobia.
Medication-overuse headache is also a differential diagnosis
of this condition.
Medication-overuse headache, (also known as Medication
rebound headache) could develop after Regular overuse of
drugs for more than 3 months. Subjects with history of self
administration of drugs, and use of over the counter pain
killers for more than 3 months were thus excluded from the
study [8].
There seems to be altered pain perception in chronic tension-
type headache patients. This change of perception seems to
influence the conversion of frequent to chronic variant of
Tension-type headache [10]. Certain authors like Jones
classify bilateral mid-facial segmental pain (MFP) as a
component of Primary headache specially the Tension-type
headache pain. Tension type headache leads pain in the
frontal, parietal, temporal in distribution [12].
The current model of Tension type headache attributes a
Neurotransmitter probably Nitric oxide excess in second
order neuron at the trigeminal nucleus sub-caudalis, leading
to Hypersensitivity and release [13]. Nitric oxide inhibitors
seem to be efficacious in treatment of Chronic Tension type
headaches. Skin over the forehead and Temporal is
particularly rich in Trigeminal nerve, which also supplies
most of the scalp including the Occipital region. This
explains the pain distribution in Tension type headache [14].
Pericranial tenderness is tenderness of pericranial myofascial
tissues, soft tissue and muscle attachements that surround the
skull: the Frontalis, Temporalis, Masseter, Pterygoid,
Sternomastioid and Trapezius muscles. This can be done by
hand palpation or by an algometer and graded on a 4 point
scale [16]. Pericranial tenderness is a very sensitive sign in
the diagnosis of Chronic tension type headache, present in
94% of the cases in our study. This may be the most
important clinical sign of Chronic tension type headache
[15].
Sinusitis can lead to dull aching pain lasting few hours in a
day, but this is accompanied by Nasal discharge and nose
block, sometimes with fever and fatigue [15, 16]. Pericranial
soft tissue tenderness can be easily confused with Paranasal
sinus tenderness which is elicited on the Sinus walls.
Tenderness of muscles is a differentiating point for Tension
type headache.
8. Conclusions
8.1. We conclude, Chronic tension type headache is a
clinical condition with onset around youth (25 years of
age 20-30), and a chronic variable course lasting many
years. The average duration of suffering being 2.2 years.
(2.2+/- 0.76).
8.2. Majority of patients suffer from a bearable type of
variable moderate intensity pain (6 on VAS) lasting few
hours on most of the days.
8.3. Pericranial tenderness is a important, underutilized
diagnostic sign of Chronic tension type headache. This
must not be confused with Paranasal sinus tenderness
which is a entirely different condition altogether.
Paper ID: 12013140 152
4. International Journal of Science and Research (IJSR), India Online ISSN: 2319-7064
Volume 2 Issue 9, September 2013
www.ijsr.net
References
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Chapter 17 Cummings: Otolaryngology: Head & Neck
Surgery, 4th ed.
[2] Lars Bendtsen and RigmorJensen in “Tension-type
headache” in “Neurologic Clinics of North America”
Neurol Clin 27 (2009) 525–535 Elsevier 2009
http://neurologic.theclinics.com
[3] Christensen M, Bendtsen L, Ashina M, et al.
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with Episodic headache” in Chapter 1 Advance therapy
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Author Profile
Rajamani Santhosh Kumar received M.B.B.S
and M.S. (E.N.T) degrees from TN Dr MGR
Medical University in 2005 and 2010
respectively with gold medals and awards.
During 2010 -2011 he worked as a faculty at the
Tagore Medical College Hospital, Chennai as
Assistant Professor of ENT. In 2012 he worked
in Hinduja Hospital, Mumbai where he obtained world class
training in ENT Surgery. In 2012, he received the Diplomate of
National board certification D.N.B in E.N.T. He is now working in
Sri Lakshmi Narayana Institute of Medical Sciences, Puducherry as
Assistant Professor of ENT. He is very actively involved in the
academic pursuits of teaching, practicing and research in ENT,
Head and Neck Surgery. He is now a Postgraduate faculty of the
institute.
K Rathna Kumar completed his M.B.B.S, D.O and
M.S. (Ophthalmology) from the prestigious Rajah
Muthiah Medical College and Hospital, Annamalai
University. He is currently working as Associate
Professor in the Department of Ophthalmology at Sri Lakshmi
Narayana Institute of Medical Sciences, Puducherry. He has been
involved in Undergraduate teaching programme and has been
performing Phaco and Manual Phaco surgeries. He is practicing
comprehensive eye care.
Paper ID: 12013140 153