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Md. Nazrul Islam
Roll No: 1280
Introduction
• Citric acid is the most important organic acid produced in tonnage
(around 736000 tones/year) and is extensively used in food (60%)
and pharmaceutical industries (10%).
• It is produced mainly by submerged fermentation using Aspergillus
niger or Candida sp.
• from different sources of carbohydrates, such as molasses and
starch based media.
• Major applications include the following industries:
• Beverages
• Candy
• Dairy products
• Pharmaceuticals
• Metal cleaning and so on.
Production Techniques And
Raw Materials
• Mostly produced from starch or sucrose based media but a
variety of raw materials such as molasses, several starchy
materials and hydrocarbons have also been employed.
• The submerged fermentation (SmF) process is the
commonly employed technique (about 80% of world
production). Several advantages such as higher yields and
productivity and lower labour costs are the main reasons
for this.
• Two types of fermenters, conventional
stirred fermenters and tower
fermenters are employed.
Product Recovery &
Fututre Perspectives
• Accomplished by three basic procedures, precipitation,
extraction, and adsorption and absorption
• Extraction is performed when intended to use as food and
drugs whereas precipitation is the classical pathway that
utilizes calcium oxide hydrate, sulphuric acid, active carbon &
vacuum crystallizers to prepare anhydrous citric acid.
Perspectives:
• Use of alternative raw materials to produce citric acid by SmF,
LSC, and SSF seems to be a suitable possibility.
• Another area is the strain improvement with
improved substrate utilization efficiency.
References
• Vandenberghe, L.P., Soccol, C.R., Pandey, A. and Lebeault,
J.M., 1999. Microbial production of citric acid. Brazilian
Archives of Biology and Technology, 42(3), pp.263-276.
• https://en.wikipedia.org/wiki/Aspergillus_niger#/media/File:Aspergillus_n
iger_SEM.jpg
• http://www.kasel.com/citric-acid-plant-in-czech-republic/

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Citric Acid Fermentation

  • 2. Introduction • Citric acid is the most important organic acid produced in tonnage (around 736000 tones/year) and is extensively used in food (60%) and pharmaceutical industries (10%). • It is produced mainly by submerged fermentation using Aspergillus niger or Candida sp. • from different sources of carbohydrates, such as molasses and starch based media. • Major applications include the following industries: • Beverages • Candy • Dairy products • Pharmaceuticals • Metal cleaning and so on.
  • 3. Production Techniques And Raw Materials • Mostly produced from starch or sucrose based media but a variety of raw materials such as molasses, several starchy materials and hydrocarbons have also been employed. • The submerged fermentation (SmF) process is the commonly employed technique (about 80% of world production). Several advantages such as higher yields and productivity and lower labour costs are the main reasons for this. • Two types of fermenters, conventional stirred fermenters and tower fermenters are employed.
  • 4. Product Recovery & Fututre Perspectives • Accomplished by three basic procedures, precipitation, extraction, and adsorption and absorption • Extraction is performed when intended to use as food and drugs whereas precipitation is the classical pathway that utilizes calcium oxide hydrate, sulphuric acid, active carbon & vacuum crystallizers to prepare anhydrous citric acid. Perspectives: • Use of alternative raw materials to produce citric acid by SmF, LSC, and SSF seems to be a suitable possibility. • Another area is the strain improvement with improved substrate utilization efficiency.
  • 5. References • Vandenberghe, L.P., Soccol, C.R., Pandey, A. and Lebeault, J.M., 1999. Microbial production of citric acid. Brazilian Archives of Biology and Technology, 42(3), pp.263-276. • https://en.wikipedia.org/wiki/Aspergillus_niger#/media/File:Aspergillus_n iger_SEM.jpg • http://www.kasel.com/citric-acid-plant-in-czech-republic/