The document describes a design that uses both physical and virtual F5 BIG-IP Local Traffic Manager devices in a Cisco Virtualized Multiservice Data Center (VMDC) solution to provide high availability, security, and optimization of application services and traffic. The design incorporates BIG-IP devices at the edge of the network and within each tenant virtual private zone. The BIG-IP devices provide load balancing, SSL offloading, health monitoring, and session persistence for applications servers. The design is aligned with Cisco VMDC reference architectures and consumption models to provide isolation and services to multiple tenants on a shared infrastructure.