The circulatory system is responsible for transporting materials such as oxygen, carbon dioxide, nutrients, hormones, and waste throughout the body using a double circulation mechanism. The heart consists of four chambers: the left side handles oxygenated blood from the lungs to the body, while the right side manages deoxygenated blood returning from the body to the lungs. Valves within the heart prevent backflow and ensure proper blood flow through the atria and ventricles.