Definition Complications of Shock Overview on Types of Shock Cardiogenic Shock Hypovolemic Shock Sepsis, Septic Shock and SIRS Other conditions of Shock

1. CIRCULATORY SHOCK
&
Its types

2. SYNOPSIS
Definition
Complications of Shock
Overview on Types of Shock
Cardiogenic Shock
Hypovolemic Shock
Sepsis, Septic Shock and SIRS
Other conditions of Shock

3. • Shock is a state in which diminished cardiac output or
reduced effective circulating blood volume impairs
tissue perfusion and leads to cellular hypoxia.
• At the outset, the cellular injury is reversible; however,
prolonged shock eventually leads to irreversible tissue
injury and is often fatal.
CIRCULATORY SHOCK - INTRODUCTION

4. COMPLICATIONS OF SHOCK
• Shock may complicate :
Severe hemorrhage
Extensive trauma or burns
Myocardial infarction
Pulmonary embolism
Microbial sepsis

5. MNEMONIC

7. CARDIOGENIC SHOCK
Cardiogenic shock results from low cardiac output as a
result of myocardial pump failure.
 It may be caused by
myocardial damage (infarction)
ventricular arrhythmias
extrinsic compression (cardiac tamponade)
outflow obstruction (e.g., pulmonary embolism)

8. HYPOVOLEMIC SHOCK
• Hypovolemic shock results from low cardiac output
due to loss of blood or plasma volume.
• E.g., resulting from hemorrhage or fluid loss from
severe burns.

10. SEPSIS, SEPTIC SHOCK AND SIRS
Sepsis, septic shock, and the systemic
inflammatory response syndrome are
interrelated and somewhat overlapping
conditions.
The definitions that follow are based on The Third
International Consensus Definitions for Sepsis
and Septic Shock

11. SEPSIS
Sepsis is defined as life threatening organ
disfunction caused by a dysregulated post
response to infection.

13. SEPTIC SHOCK
Septic shock is defined as a subset of sepsis
in which particularly profound circulatory,
cellular, and meta- bolic abnormalities are
associated with a greater risk of mortality
than with sepsis alone.

14. SYSTEMIC INFLAMMATORY RESPONSE SYNDROME
 Systemic inflammatory response syndrome (SIRS) is asepsis-like
condition associated with systemic inflammation that may be triggered
by a variety of nonmicrobial insults, such as burns, trauma,and/or
pancreatitis.
 Pathogenic featurecommon to SIRS and septic shock is a massive
outpouring of inflammatory mediators from innate and adaptive immune
cells that produce arterial vasodilation, vascular leakage, and venous
blood pooling.

15. The cardiovascular abnormalities associated
with SIRS result in tissue hypoperfusion,
cellular hypoxia, and metabolic derangements
that lead to organ dysfunction and, if severe
and persistent, organ failure and death.

16. OTHER CONDITIONS OF SHOCK
NEUROGENIC SHOCK :- Shock can result from a loss of
vascular tone associated with anesthesia or secondary
to a spinal cord injury.
ANAPHYLACTIC SHOCK :- results from systemic
vasodilation and increased vascular permeability that
is triggered by an immunoglobulin E–mediated
hypersensitivity reaction

17. SUMMARY