Liver Resection VS Transplantation in Resectable Peri-Hilar Cholangiocarcinom...Eric Vibert, MD, PhD
Five year Intent-to-treat survival is 70% after Radio-Chemotherapy and Liver transplantation in UNRESECTABLE peri-hilar cholangiocarcinoma... Why reserve this treatment to unresectable liver tumor... We designed this prospective French multicentric study to test if radiochemotherapy and liver transplantation give better result than liver resection... All French HPB Center are concern so include patient in TRANSPHIL
Liver Resection VS Transplantation in Resectable Peri-Hilar Cholangiocarcinom...Eric Vibert, MD, PhD
Five year Intent-to-treat survival is 70% after Radio-Chemotherapy and Liver transplantation in UNRESECTABLE peri-hilar cholangiocarcinoma... Why reserve this treatment to unresectable liver tumor... We designed this prospective French multicentric study to test if radiochemotherapy and liver transplantation give better result than liver resection... All French HPB Center are concern so include patient in TRANSPHIL
2. 局限性…
作者 年 人数 90天死亡率 Underlying Parenchyma
Greco et al. 2001-2005 129 4.1% Abnormal Liver
Rosaye et al 2005-2011 2342 3.5% Abnormal Liver
Zhong et al 2000-2007 908 3.1% Abnormal Liver
Vigano et al 2000-2012 192 2.1% Abnormal Liver
Donadon et al 2004-2013 336 2% Abnormal Liver
Kim et al 2005-2010 454 0.7% Healthy Liver
Zhou et al 2006-2009 124 0.5% Healthy Liver
Faber et a; 2000-2010 148 0% Healthy Liver
5%肝硬化病人术后死亡率低于5%为“可接受”
33. 我们的经验
1992 – 2014 : 43 pts
Vp1/Vp2 : 8 pts
Vp3/Vp4 : 35 pts
50%
30%
19%
35%
Atrophy of the side of the tumoral thrombus is the most important prognostic factor
34. 手术 vs TACE (HCC 及门脉栓塞)
Vp1 Vp2
Vp3 Vp4
Peng et al. Cancer 2012