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CEO Board Update
Seth Berkley, MD
29 November 2017, Vientiane, Lao PDR
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Remembering Olga Popova
Board meeting
29-30 November 2017
Valued friend to Gavi 2009-2014 as
a PPC Member, alternate
Board Member & Governance
Committee Member
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Lao PDR’s road to transition
Board meeting
29-30 November 2017
Support for immunisation
and health systems
strengthening since 2001
2017: First year of
accelerated transition
52% 53 49
45
49
57
50
61
67
74
78
79
87 88 89
82%
Coverage with DTP
containing vaccines %
HepatitisB
Pentavalent
Inactivatedpolio
Pneumococcal
HPVdemo
Seconddoseof
Measles&Rubella
Japanese
Encephalitis
1
Board meeting
29-30 November 2017
KEY DEVELOPMENTS
IN OUR GLOBAL
LANDSCAPE
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
New WHO leadership team
Key developments
New Gavi Board representation
Dr Soumya Swaminathan
Deputy Director-General for Programmes
Dr Princess Nothemba (Nono) Simelela
Assistant Director-General for Family,
Women, Children and Adolescents
Bold work plan for 2019-2023; new ways of working, more accountability,
outcomes focus & partnership with two important areas for Gavi:
• the role immunisation plays in Universal Health Care
• the importance of immunisation and how measured in the Sustainable Development Goal indicators
Board meeting
29-30 November 2017
Dr Tedros, Director General
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
The wider benefit of immunisation
Board meeting
29-30 November 2017
TERTIARY
SECONDARY
PRIMARY
HEALTH CARE
Towards
universal health
coverage
Build out system
to reach the
remainder
14%86%Children reached through routine
immunisation worldwide
ROUTINE IMMUNISATION
Key developments
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Leadership changes for partners
Key developments
Tony Lake
Search processbegun
for UNICEF leadership
Board meeting
29-30 November 2017
Peter Sands
New Global Fund Executive
Director
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Gavi’s work has a direct relationship with 14 of the 17
Sustainable Development Goals
Board meeting, 29-30 November 2017
Goal 5: Gender equality
In most countries and at the
global aggregate level,
immunisation reaches girls
and boys equally
Goal 8: Decent work and
economic growth
Parents of immunised and
healthy children are able to work
and engage in economic activity.
Healthy children grow into a
productive future workforce that
builds household incomes and
stronger economies
Goal 1: No poverty
Health is Wealth: For every US$ 1
invested in immunisation in low-
and middle-income countries,
there is an estimated US$ 48 net
benefit of longer, healthier lives
Key developments
Goal 17: Partnership
for the Goals
Immunisation progress over
the last few decades was
transformed by a public-private
approach that combined the
best of both sectors to develop,
test, finance and deliver
affordable vaccines to more
children in need
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Non-health SDGs setting bold aspirations
Key developments
Board meeting
29-30 November 2017
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Immunisation indicator for Sustainable Development Goals
Board meeting
29-30 November 2017
Likely indicator:
• DTP3
• PCV last dose
• MCV2
• HPV last dose
Long-term goal:
• Child-centric view: full immunisation with
all 12 vaccines universally recommended
by WHO for children & adolescents
MCV2
DTP3
PCV last
HPV last
How to measure?
Key developments
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Vaccine hesitancy, impact in Gavi countries
Board meeting
29-30 November 2017
Key developments
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaKey developments
Outbreak map, managed by Gavi,
housed on Vaccines Work
Board meeting
29-30 November 2017
Through Social Media watching, we see hesitancy hotspots
positive neutral negative
Increasing use of digital platforms to support the alliance’s work
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Changes to our donor landscape
Board meeting
29-30 November 2017
Elections
New contributions
Norway
Netherlands
Germany
Japan
Key developments
Donor Country
Governments
Sweden
Denmark
India
United Arab
Emirates
Republic
of Korea
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
97,913,000
doses
6 vaccines
Vaccine
manufacturers
18 vaccines (if
Board approves
typhoid)
Manufacturer landscape
Board meeting
29-30 November 2017
Key developments
• Leadership changes since last replenishment
• Increasingly diverse & complex
supplier landscape
2001 2005 2010 2015 2017
NumberofGavi
fundeddoses
49,901,000
doses
6 vaccines
567,062,000 doses
17 vaccines
155,690,500
doses
10 vaccines
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
159 m
average of number ofdoses
shipped across 2017-2019
Evolution of the penta market
how Gavi has been a catalyst for market shaping through growing demand
Board meeting
29-30 November 2017
Source: Gavi Base Demand
Forecast, based on UNICEF
Shipment Data
Scope: Gavi countriesprocuring
through UNICEF (excluding
Indonesia)
Key developments
Number ofGavi/UNICEF suppliers Number ofshipped doses
2.8 m
doses requested
in 2001
193.7 m
doses shipped
in 2016
Increasing volumes, reducing pricechanging number of suppliers,
Predicted to
move towards
US$ ~0.80
per dose by 2019
US$ 1.55
US$ 3.49
All data points for
2017-2019 are estimates
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
New groups to accelerate vaccine R&D
3 targets
• Middle East Respiratory Syndrome
• Lassa fever
• Nipah
Based on the potential to become global public
health emergencies and have a feasible
development approach for a vaccine
Next– call for proposals for platform technologies
Board meeting
29-30 November 2017
Key developments
2
Board meeting
29-30 November 2017
REPORTING BACK
ON PREVIOUS BOARD
DECISIONS
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Nigeria in transition case study
Board meeting
29-30 November 2017
Previous Board decisions
ResultsUK
‘The impactof UK
aid’November2017
‘Nigeria illustrates
that focusing on
economic
indicators alone to
determine access
to donor financing
is a high-risk
strategy’
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Board meeting
29-30 November 2017
Save The Children,
October 2017
Johns Hopkins IVAC,
November 2017
Pneumonia & diarrhoea remain leading killers of children
Previous Board decisions
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Scale-up of immunisation ahead of other pneumonia and
diarrhoea interventions
Board meeting
29-30 November 2017
• Vaccine coverage performance outweighs non vaccine performance
• Of the 15 countries in this report, none met the non-vaccine intervention targets for
Pneumonia or Diarrhoea
Vaccine Interventions Non-vaccine Interventions
Previous Board decisions
Source: Johns Hopkins IVAC, November 2017
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Rapid scale-up in pneumococcal conjugate vaccine
Previous Board decisions
LIC coverage
close to HIC
coverage
MICs still
lagging
Board meeting
29-30 November 2017
170
103
83
57
47
30
0
50
100
150
200
0
20
40
60
80
100
Number of countries
with PCV introduced
140
155
2011 2012 2013 2014 2015 2016
PCV3 coverage,%
124
2008 2009 2010
MICs (Gavi 68)
HIC
LICs
Number of countries
MICs (non-Gavi68)
Source: WUENIC data, July 2017 release
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Rotavirus vaccine coverage in low income
countries now above high-income
Previous Board decisions
LIC coverage
now above HIC
coverage
MICs still
lagging
Board meeting
29-30 November 2017
42
30282316
0
50
100
150
200
0
10
20
30
40
50
Rota coverage,%
201020092008
Number of countries
with Rota introduced
2016
86
2015
82
2014
73
2013
53
20122011
Number of countries
HIC
MICs (non-Gavi68)
MICs (Gavi 68)
LICs
Source: WUENIC data, July 2017 release
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions
Scaling up pneumococcal and rotavirus vaccine in India
‘In India, by introducing and scaling up
coverage of vaccination programs targeting
pneumonia and diarrhoea, India could save
over US$ 1 billion each year in economic
benefits and avert more than 90,000
needless child deaths each year’.
Johns Hopkins, IVAC2017
Board meeting
29-30 November 2017
Political commitment from PM Modi: Intensified Mission Indradhanush:
Aim to reach 90% full immunisation coverage by 2018
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions
Continued acceleration in India
November 2017June 2017
• Phase 1 campaign in 5 states
reaching >33 million
• Initial launch in May in 3 of
highest burden states
• Expanded to 4 new states in addition
to 4 from 2016 (domestically financed)
• Phase 2 campaign in 8 states
reaching >28 million to date
• >0.5 million immunised to date
• Expanded to another 1 state
• >11 million immunised to date
Pneumococcal
vaccine
Rotavirus
vaccine
Penta3 coverage
Measles-rubella
vaccine
• 2015 WUENIC: 87%, 3.2M under-
immunised
• 2016 WUENIC: 88%, 2.9 million
under-immunised
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Measles mortality at record low
Previous Board decisions
Board meeting
29-30 November 2017
550,021
89,663
402,013
466,148
149,314
200,799
145,794
Gavi progress in 2017
• 10 measles / MR campaigns in 2017 and
1 routine introduction (Lao PDR)
• India: largest ever MR campaign >400m
• Indonesia: <15yo MR campaign >67m
Challenges
• Long term planning and budgeting
• MCV1 coverage in Gavi73 countries flat at 78%
• Campaigns still business as usual vs. focus on
unreached & move to RI
• IRC: Epidemiological analysis not sufficiently robust
to inform planned activities; use of modelling
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions
49%
72%
Low polio3 coverage – risk to achieving & sustaining
eradication
Endemic country
cVDPV type 2
WPV type 1
Board meeting
29-30 November 2017
60%
Cases to date in 2017
Data source:GPEI; WUENIC 2016
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions
Niger: 67%
Chad: 46%
CAR: 47%
Yemen: 71%
Ethiopia: 77%
Somalia: 47%
South Sudan: 31%
DR Congo: 79%
Madagascar: 77%
Syria: 42%
49%
60%
72%
Endemic country
cVDPV type 2
WPV type 1
Cases to date in 2017
Data source:GPEI; WUENIC 2016
Low polio3 coverage – risk to achieving & sustaining
eradication
Board meeting
29-30 November 2017
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Polio Transition – no country yet to finalise their plan
Previous Board decisions
Board meeting, 29-30 November 2017
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
August 2017 – first Gavi grant disbursement
2017 UNICEF progress report
• Increased coverage
• 31 Health Facilities reopened
Board meeting
29-30 November 2017
Previous Board decisions
Syria
Unfortunately continued challenges
• Outbreaks: cVDPV2 70 cases, Measles 7,000 cases
• Cold chain & vaccine attack in al-Mayadin, near Deir al-Zor,
Eastern Syria (October) – centre of polio outbreak
• Loss of 100,000 measles, 35,000 polio doses & equipment
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Yemen – Acute Humanitarian Crisis
Board meeting
29-30 November 2017
Growing humanitarian crisis
• >60% of people food insecure,>30% depend onfood aid
• >50% need help to access drinkingwater and sanitation
• ~50% of health facilities non-functional, >10M people lack
accessto basic healthcare
Ongoingoutbreaks
• Cholera: ~950,000 cases. Waning but continued risk
• Diphtheria:120 cases diagnosed,14 deaths. >1m children
at risk
Response
• Partners working to deliver food,fuel & vaccines – 1.9M
routine vaccine doses (mainly penta / PCV) arrived this week
• WHO and UNICEF conducting outreach campaigns with Gavi
support– constrained by access challenges and blockade
Previous Board decisions
Source: WHO Weekly Epidemiological
Bulletin (21 November 2017),UN OCHA
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions
Cholera: affected countries, October 2017
Countries reporting
cholera, 2010-2016
Countries reporting
cholera, 2017
Somalia
77,783 cases
Haiti
12,167 cases
Yemen
945,362 cases
South Sudan
21,530 cases
DR Congo
42,334 cases
Sudan
35,354 cases
Nigeria
5,336 cases
Ethiopia
47,711cases
Board meeting
29-30 November 2017
Approved for Gavi
vaccine support
in 2017
Cameroon Malawi
Mozambique
Sierra Leone
Source: WHO Cholera Update 17 Nov 2017
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions
Oral cholera vaccine: impact of our investment
0
2
4
6
8
10
12
14
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017
Numberofdosesusedglobally(millions)
Board meeting
29-30 November 2017
(to end
October)
Euvichol
Shanchol
Dukoral
Shanchol
prequalified
Creation of
stockpile/Gavi
investment
Euvichol
prequalified
Gavi support for
operational costs
13,322,316
approved doses
in 2017 to date, 17m
by year end
Next version of Euvichol
• Less expensive
• Ease of storage and
transportation
• Ease of administration
and waste management
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Ending Cholera Strategy
Board meeting
29-30 November 2017
Previous Board decisions
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
International Coordinating Group
Board meeting
29-30 November 2017
Previous Board decisions
• Board-approved support based on key principles
• Stockpiles part of comprehensive disease strategy
• Transparency & accountability in decision-making
• Coherent,Alliance-wide forecastsand procurement
• Decision criteria more transparent, information
shared in real time & Gavi Secretariat observing
ICG discussions
• Independent evaluation recommendations
• Formal governance structure with new oversight body
• Clearer definition of roles and responsibilities
• More standardised reporting
• Continue to strengthen linkages with disease control
strategies;create global strategy for meningitis control
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Slow progress in implementing Eliminating Yellow Fever
Epidemics strategy
Mass preventive
campaigns
Ghana
Nigeria
Sudan
DR Congo (application
January 2018)

New applications for
routine YF vaccination
Ethiopia
Sudan
South Sudan
Uganda
Strengthened governance
and accountability
Global level
governance structure
has been formed
Key working groups
not yet operational








Board meeting
29-30 November 2017
Previous Board decisions

Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Yellow Fever coverage stagnant, tracking below MCV1
given same time
Board meeting
29-30 November 2017
0%
20%
40%
60%
80%
2008 2010 2012 2014 2016
YF coverage across
22 at-risk countries Chad – MCV1 and YF
0%
20%
40%
60%
80%
2008 2010 2012 2014 2016
Yellow Fever MCV1
Previous Board decisions
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Nigeria yellow fever outbreak
Board meeting
29-30 November 2017
States with confirmed cases
States with suspected cases
Main cities
Coverage:
12.6%
67.5%
55.7%
12.2%
66.3%
50.8%
65.5%
Source: NICS survey, Nigeria CDC
Previous Board decisions
• 179 suspected cases, 15
confirmed. 2 confirmed deaths
• ICG approved a 960,000 doses in
October and 1.4M doses in
November for outbreak response
• 61M doses approved for preventive
campaign in 2012, only 12M
shipped due to supply constraints
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Campaigns & Routine Immunisation of Meningitis A vaccine
have led to virtual elimination of disease
38
450 million people
live in Africa’s “meningitis belt”
across 26 countries
>287m people
vaccinated
in 2010-2016
January -
2 July 2017
Niger
Burkina Faso
Mali
842
156
16
IMPACT:
Number of meningitis A cases:
in 2008
0
0
0
21out of 26
countries
partially or totally
vaccinatedby
MenAfriVac
Board meeting
29-30 November 2017
Sources:
www.who.int/csr/disease/meningococcal/Bulletin_Meningite_S26_2017.pdf
2010–2016: >235mn (until Feb 2016) people vaccinated:
http://immunizationinafrica2016.org/releases/2016/2/23/as-meningitis-nears;
4,069,239: target group for MenA - WHO administrative coverage JRF file -
Ghana, Niger, Senegal, Sudan (2016)
Previous Board decisions
Nigeria
• IRC approved 36m+ doses for
catch-up campaign, 6m for routine
• Majority of doses produced: risk of
expiry if not used
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions
Ebola
Advanced Purchase Commitment with Merck VSV-EBOV for
stockpile
• Acceleratedreview timelines:
- Priority Medicine scheme (EMA)
- Breakthrough Therapy designation(FDA)
• Submissionto be completed in 2018
• 300kinvestigative doses still available in the event of an outbreak
SAGE working group to reconvene H1 2018
Board meeting
29-30 November 2017
Chinese approval for local Ad-5-EBOV vaccine
• Chinese Academyof Military Medical Sciences’Bioengineering
Institute & CanSino Biologics
3
Board meeting
29-30 November 2017
STRATEGIC ISSUES
FOR DISCUSSION
The importance of data
to accelerate progress on
coverage and equity
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Above trend to immunise 300M children this period but
challenges in reaching the fifth child
Children immunisedwith
DTP3/PENTA3 (Gavi68) DTP3/PENTA3 (Gavi68)
80%80%80%78%
68%
60%
2016
2001
2005
2015
2010
2014
MCV1 (Gavi68)
78%78%78%78%
68%
60%
2016
2015
2001
2005
2014
2010
2012
60.4M
2011
60.3M
2014
62.4M
2013
60.6M
2010
59.5M
2016
63.9M
2015
63.1M
Board meeting
29-30 November 2017
Strategic questions for discussion
WHO-UNICEF Estimatesof 2016 Immunisation Coverage (release
July2017), UN Population Division (2017)
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Challenges with WUENIC data – Pakistan example
Board meeting
29-30 November 2017
WUENIC estimate
unchanged since 2012 (72%)
Coverage:Punjab
2012
DHS
2014
Punjab
MICS
2016 Punjab
Health
Survey
DTP3 62.5% 71.7% 85.2%
MCV1 49.7% 71.6% 84.6%
• Tremendous progress
since 2012
• Population of Punjab
represents nearly half
of Pakistan
Strategic questions for discussion
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
What does this mean in reality?
Challenges with WUENIC data
Strategic questions for discussion
Board meeting
29-30 November 2017
Congo Republic
73%
80%
73%
66%
WUENIC Country
Official Estimate
MICS survey
(preliminary)
Adminis-
trative
72%
61%
57%
WUENIC Country
Official Estimate
Adminis-
trative
PNG
WHO-UNICEF Estimatesof 2016 Immunisation Coverage (release
July2017), UN Population Division (2017)
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Data issue is broader than immunisation
Board meeting
29-30 November 2017
Proportionof Gavi73 wherecoverage estimates are
challengeddue to inconsistentpopulationdata
Strategic questions for discussion
+50%
WUENIC Grade of Confidence
defined:
• Administrative
coverage
• Official coverage
• Survey coverage
• Population data
All declining
as drivers of
uncertainty
Largest (and
growing)
driver of
uncertainty
WHO-UNICEF Estimatesof 2016 Immunisation Coverage (release
July2017), UN Population Division (2017)
Our data journey
Past
How do we accelerate progress?
Board meeting, 29-30 November 2017
Today Future vision
• HSS not targeted and a
“data-free zone”
• Data investments limited and
fragmented
• Limited visibility on technical
support
• Light-touch Secretariat
engagementwith countries
• GPFs for every grant with
intermediate HSS indicators
• Data SFA: Joined up approach to
data strengthening
• PEF: Full transparency on TCA
• New tools: Surveys every 5 years,
data triangulation etc.
• Enhanced dialogue: more SCMs,
JointAppraisals using data etc.
• Transformationin country data
systems based on 21st century,
digital technologies
• Data available to all those who
need it
• Data used to track children &
allow follow-up with parents
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Triangulation critical to address data challenges –
comparing shipment and consumption data in Ethiopia
• Consumption algorithm
aligns with WUENIC data
• Admin data higher than
doses available,
highlighting issues
in data system
• Can support engagement
on data quality
6M
4M
2M
0M
10M
8M
2018
est.
2017
est.
2016201520142013201220112010200920082007
Country: reporting
number of doses used
& requesting doses
Dose need
calculated from
WUENIC
Predicted
consumption: Gavi
algorithm
(shipments, stock
changes)
Strategic questions for discussion
Board meeting
29-30 November 2017
Pentavalentvaccine consumption,doses
WHO-UNICEF Estimates of 2016 Immunisation Coverage
(release July 2017)
Country request and shipping data
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Civil Society Organisations helping to strengthen data:
Coverage survey in 3 Urban Slums, Punjab province
Board meeting
29-30 November 2017
Many of the under-immunised are in slums
vs rural areas
Strategic questions for discussion
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaStrategic questions for discussion
~27,000 facilities
(95% sub-district)
~27M newborns
~30M pregnancies
~100M <5 years of age
>650M doses
>9M immunisation sessions
Complex environment
+
Barriers to Digitalisation:
• Access to
• Electricity
• Computers
• Internet
• Data entry operators
How digital data is supporting the world’s largest
immunisation programme
HOW IT WORKS
Geographic informationTemperature &
Inventory information
Temperature over timeState-based informationStock information
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
6002
1645
Pre-eVIN Post eVIN
stockouts
72%
Reduction
497
1405
880
241 241
518
68 106
464
1150
432
233 186 142
84 84
194
18 61
152
298
193
Pre-eVIN Post eVIN
Stock Out Reduction – Post eVIN
Board meeting, 29-30 November 2017
Strategic questions for discussion
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
We are expanding our partnerships with innovative
projects beyond data too
Board meeting, 29-30 November 2017
Strategic questions for discussion
Private Sector
Partners
Demand Generation
Supply Chain
Data Management
CREATE “CLUSTERS” OF FIRMS THAT PROVIDE PROVEN SOLUTIONS &
INNOVATIONS FROM WHICH COUNTRIES CAN SEEK SUPPORT
3
Board meeting
29-30 November 2017
STRATEGIC ISSUES
FOR DISCUSSION
Balancing sustainability
and new vaccine
introductions
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Balancing sustainability & new vaccine introductions
Board meeting
29-30 November 2017
Vietnam Angola
Coverage (DTP3) 96% 64%
Number of vaccines introduced 8 11
General government health expenditures as a
proportion of general government expenditures
(in 2014, the year with the most recent available data)
14.2% 5%
Vaccines as % general health expenditure
(projection at time of transition)
0.1% 1.2%
Co-financing history
Never defaulted
Multiple defaults
(2011, 2012, 2013, 2014 & 2015)
Other Strong health system;
want to introduce PCV & Rotavirus
2021-2025.
High burden of disease including HPV.
Applied once for HPV but turned down
by IRC.
Strategic questions for discussion
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Board meeting
29-30 November 2017
• Introduction of new vaccines did not affect coverage
of DTP3 vaccine in the countries studied
• Of many scenarios tested, only one proved to be
associated with changes in DTP3 and the direction
was positive
• Introductions of other new vaccines & multiple
vaccine introductions should be monitored for
immunisation and health systems impacts
Effects of Vaccine introductions on RI
Centre for Health Economics and Policy Analysis,The Bill and Melinda Gates
Foundation,International Vaccine AccessCenter,published October 2012
Strategic questions for discussion
4
Board meeting
29-30 November 2017
ALLIANCE UPDATE
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Alliance Health Survey
Board meeting
29-30 November 2017
Activities underway:
• Alliance directory for in-country and HQ colleagues
• On boarding pack for new colleagues joining the alliance
• IT solutions to share information
• Across alliance get-togethers
• Joint communication from leadership
Follow-up survey Q1 2018
• UNICEF & WHO expanding to CDC & World Bank
Alliance update
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Civil Society Organisation – stronger engagement
Board meeting
29-30 November 2017
Multiple initiatives to
support communication
and activities for increased
CSO contribution to
immunisation
Alliance update
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Board meeting
29-30 November 2017
Gavi People Survey
Alliance update
JUNE JULY SEPTEMBERAUGUST OCTOBER NOVEMBER DECEMBER
19 June 1-day Gavi Leadership
Team offsite dedicated to GPS
23 June High-level results
presentation to all staff
GPS results roll-
out to teams
Discussions within each team
to identify their priorities
13/14 Sept. Directors' 2-day
meeting to discuss GPS
results & define path forward
22 Sept. Special all staff in
DC & Geneva, deep dive
into results, identify key
drivers of challenges &
potential solutions 17 Nov. Senior Management
Team all-day meeting
Development of team and
organisational action plans
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Board meeting
29-30 November 2017
Alliance update
Update on secretariat facilities, Washington
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Board meeting
29-30 November 2017
Update on secretariat facilities, Geneva Global Health Campus
October 2015
Start of construction
February 2018 July 2018
Building handover
March 2018
The Global Fund move Gavi move
Alliance update
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Operational efficiencies at Global Health Campus
Board meeting
29-30 November 2017
Immediate efficiciencies
- Rental savings
- Facilities
management
- Security
- Printing
- IT network and
communications
To be worked on post-move
- Travel management
and security
- IT service desk
- Cyber security
- IT engineering
- Occupational health
Opportunities for
further exploration
- Procurement services
- IT software licenses
and devices
- Sharing certain IT
systems
- Aligning finance
platforms
Opportunity
to improve
services at
reduced cost
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Programmatic collaboration with the Global Fund
Alliance update
Joint advocacy
at global and
country level
Coordinating
programmatic
investments
Aligning and
contributing to
each other’s
policies
Board meeting, 29-30 November 2017
Knowledge
sharing
Joint advocacy
at global and
country level
Coordinating
programmatic
investments
Aligning and
contributing to
each other’s
policies
Board meeting, 29-30 November 2017
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Programmatic collaboration with the Global Fund
Alliance update
Knowledge
sharing
Joint advocacy
at global and
country level
Coordinating
programmatic
investments
Aligning and
contributing to
each other’s
policies
Board meeting, 29-30 November 2017
• Gavi SCMs and GF counterparts
regularly exchange country
knowledge and intelligence
• Governance teams regularly share
best practice and lessons learned
• Gavi shares fiduciary risk intelligence
and unit cost information with GF
• Aligning HSS investments where this
can address common challenges
(e.g. Burkina Faso, DRC, Ethiopia,
Liberia, Nigeria, PNG Tanzania etc.)
• Co-investing in strengthening data
(e.g., data quality assessments in
Cameroon, Chad, Malawi, Mali, etc.)
• Shared fiduciary oversight and
assurance mechanisms (e.g. DRC,
Ghana, Kenya, Madagascar)
• Joint missions to countries (e.g.,
Afghanistan, CAR, DRC, Eritrea,
Guinea-Buissau, Niger, Nigeria)
• Coordinating contribution to other
global health initiatives (e.g., GFF
Investors Group, PMNCH Board,
UHC2030 Steering Committee).
• GF was a member of the Steering
Committees for the HSIS policy and
Supply & Procurement Strategy
• Gavi and GF collaborated closely on
fragility policy review
• Collaborated closely on developing
operational guidelines (e.g., fragility,
HR capacity and incentives, country
team approaches)
Knowledge
sharing
Joint advocacy
at global and
country level
Coordinating
programmatic
investments
Aligning and
contributing to
each other’s
policies
Board meeting, 29-30 November 2017
5
Board meeting
29-30 November 2017
BOARD AGENDA
Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda
Ambitious agenda, important decisions
Board meeting
29-30 November 2017
Board agenda
• Financial forecast
• Risk & Assurance Report
• Partners’ Engagement Framework & budget
• Typhoid containing vaccine support
• Country programmes & strategic issues
• Vaccine Investment Strategy
• Country engagement post-transition
• Nigeria & PNG strategies
25% reduction in
length of Board pack
Investment trade-off
framework
www.gavi.org
Thank you

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CEO Board update 29 Nov 2017

  • 1. www.gavi.org CEO Board Update Seth Berkley, MD 29 November 2017, Vientiane, Lao PDR
  • 2. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Remembering Olga Popova Board meeting 29-30 November 2017 Valued friend to Gavi 2009-2014 as a PPC Member, alternate Board Member & Governance Committee Member
  • 3. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Lao PDR’s road to transition Board meeting 29-30 November 2017 Support for immunisation and health systems strengthening since 2001 2017: First year of accelerated transition 52% 53 49 45 49 57 50 61 67 74 78 79 87 88 89 82% Coverage with DTP containing vaccines % HepatitisB Pentavalent Inactivatedpolio Pneumococcal HPVdemo Seconddoseof Measles&Rubella Japanese Encephalitis
  • 4. 1 Board meeting 29-30 November 2017 KEY DEVELOPMENTS IN OUR GLOBAL LANDSCAPE
  • 5. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda New WHO leadership team Key developments New Gavi Board representation Dr Soumya Swaminathan Deputy Director-General for Programmes Dr Princess Nothemba (Nono) Simelela Assistant Director-General for Family, Women, Children and Adolescents Bold work plan for 2019-2023; new ways of working, more accountability, outcomes focus & partnership with two important areas for Gavi: • the role immunisation plays in Universal Health Care • the importance of immunisation and how measured in the Sustainable Development Goal indicators Board meeting 29-30 November 2017 Dr Tedros, Director General
  • 6. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda The wider benefit of immunisation Board meeting 29-30 November 2017 TERTIARY SECONDARY PRIMARY HEALTH CARE Towards universal health coverage Build out system to reach the remainder 14%86%Children reached through routine immunisation worldwide ROUTINE IMMUNISATION Key developments
  • 7. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Leadership changes for partners Key developments Tony Lake Search processbegun for UNICEF leadership Board meeting 29-30 November 2017 Peter Sands New Global Fund Executive Director
  • 8. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Gavi’s work has a direct relationship with 14 of the 17 Sustainable Development Goals Board meeting, 29-30 November 2017 Goal 5: Gender equality In most countries and at the global aggregate level, immunisation reaches girls and boys equally Goal 8: Decent work and economic growth Parents of immunised and healthy children are able to work and engage in economic activity. Healthy children grow into a productive future workforce that builds household incomes and stronger economies Goal 1: No poverty Health is Wealth: For every US$ 1 invested in immunisation in low- and middle-income countries, there is an estimated US$ 48 net benefit of longer, healthier lives Key developments Goal 17: Partnership for the Goals Immunisation progress over the last few decades was transformed by a public-private approach that combined the best of both sectors to develop, test, finance and deliver affordable vaccines to more children in need
  • 9. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Non-health SDGs setting bold aspirations Key developments Board meeting 29-30 November 2017
  • 10. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Immunisation indicator for Sustainable Development Goals Board meeting 29-30 November 2017 Likely indicator: • DTP3 • PCV last dose • MCV2 • HPV last dose Long-term goal: • Child-centric view: full immunisation with all 12 vaccines universally recommended by WHO for children & adolescents MCV2 DTP3 PCV last HPV last How to measure? Key developments
  • 11. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Vaccine hesitancy, impact in Gavi countries Board meeting 29-30 November 2017 Key developments
  • 12. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaKey developments Outbreak map, managed by Gavi, housed on Vaccines Work Board meeting 29-30 November 2017 Through Social Media watching, we see hesitancy hotspots positive neutral negative Increasing use of digital platforms to support the alliance’s work
  • 13. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Changes to our donor landscape Board meeting 29-30 November 2017 Elections New contributions Norway Netherlands Germany Japan Key developments Donor Country Governments Sweden Denmark India United Arab Emirates Republic of Korea
  • 14. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda 97,913,000 doses 6 vaccines Vaccine manufacturers 18 vaccines (if Board approves typhoid) Manufacturer landscape Board meeting 29-30 November 2017 Key developments • Leadership changes since last replenishment • Increasingly diverse & complex supplier landscape 2001 2005 2010 2015 2017 NumberofGavi fundeddoses 49,901,000 doses 6 vaccines 567,062,000 doses 17 vaccines 155,690,500 doses 10 vaccines
  • 15. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda 159 m average of number ofdoses shipped across 2017-2019 Evolution of the penta market how Gavi has been a catalyst for market shaping through growing demand Board meeting 29-30 November 2017 Source: Gavi Base Demand Forecast, based on UNICEF Shipment Data Scope: Gavi countriesprocuring through UNICEF (excluding Indonesia) Key developments Number ofGavi/UNICEF suppliers Number ofshipped doses 2.8 m doses requested in 2001 193.7 m doses shipped in 2016 Increasing volumes, reducing pricechanging number of suppliers, Predicted to move towards US$ ~0.80 per dose by 2019 US$ 1.55 US$ 3.49 All data points for 2017-2019 are estimates
  • 16. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda New groups to accelerate vaccine R&D 3 targets • Middle East Respiratory Syndrome • Lassa fever • Nipah Based on the potential to become global public health emergencies and have a feasible development approach for a vaccine Next– call for proposals for platform technologies Board meeting 29-30 November 2017 Key developments
  • 17. 2 Board meeting 29-30 November 2017 REPORTING BACK ON PREVIOUS BOARD DECISIONS
  • 18. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Nigeria in transition case study Board meeting 29-30 November 2017 Previous Board decisions ResultsUK ‘The impactof UK aid’November2017 ‘Nigeria illustrates that focusing on economic indicators alone to determine access to donor financing is a high-risk strategy’
  • 19. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Board meeting 29-30 November 2017 Save The Children, October 2017 Johns Hopkins IVAC, November 2017 Pneumonia & diarrhoea remain leading killers of children Previous Board decisions
  • 20. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Scale-up of immunisation ahead of other pneumonia and diarrhoea interventions Board meeting 29-30 November 2017 • Vaccine coverage performance outweighs non vaccine performance • Of the 15 countries in this report, none met the non-vaccine intervention targets for Pneumonia or Diarrhoea Vaccine Interventions Non-vaccine Interventions Previous Board decisions Source: Johns Hopkins IVAC, November 2017
  • 21. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Rapid scale-up in pneumococcal conjugate vaccine Previous Board decisions LIC coverage close to HIC coverage MICs still lagging Board meeting 29-30 November 2017 170 103 83 57 47 30 0 50 100 150 200 0 20 40 60 80 100 Number of countries with PCV introduced 140 155 2011 2012 2013 2014 2015 2016 PCV3 coverage,% 124 2008 2009 2010 MICs (Gavi 68) HIC LICs Number of countries MICs (non-Gavi68) Source: WUENIC data, July 2017 release
  • 22. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Rotavirus vaccine coverage in low income countries now above high-income Previous Board decisions LIC coverage now above HIC coverage MICs still lagging Board meeting 29-30 November 2017 42 30282316 0 50 100 150 200 0 10 20 30 40 50 Rota coverage,% 201020092008 Number of countries with Rota introduced 2016 86 2015 82 2014 73 2013 53 20122011 Number of countries HIC MICs (non-Gavi68) MICs (Gavi 68) LICs Source: WUENIC data, July 2017 release
  • 23. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions Scaling up pneumococcal and rotavirus vaccine in India ‘In India, by introducing and scaling up coverage of vaccination programs targeting pneumonia and diarrhoea, India could save over US$ 1 billion each year in economic benefits and avert more than 90,000 needless child deaths each year’. Johns Hopkins, IVAC2017 Board meeting 29-30 November 2017 Political commitment from PM Modi: Intensified Mission Indradhanush: Aim to reach 90% full immunisation coverage by 2018
  • 24. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions Continued acceleration in India November 2017June 2017 • Phase 1 campaign in 5 states reaching >33 million • Initial launch in May in 3 of highest burden states • Expanded to 4 new states in addition to 4 from 2016 (domestically financed) • Phase 2 campaign in 8 states reaching >28 million to date • >0.5 million immunised to date • Expanded to another 1 state • >11 million immunised to date Pneumococcal vaccine Rotavirus vaccine Penta3 coverage Measles-rubella vaccine • 2015 WUENIC: 87%, 3.2M under- immunised • 2016 WUENIC: 88%, 2.9 million under-immunised
  • 25. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Measles mortality at record low Previous Board decisions Board meeting 29-30 November 2017 550,021 89,663 402,013 466,148 149,314 200,799 145,794 Gavi progress in 2017 • 10 measles / MR campaigns in 2017 and 1 routine introduction (Lao PDR) • India: largest ever MR campaign >400m • Indonesia: <15yo MR campaign >67m Challenges • Long term planning and budgeting • MCV1 coverage in Gavi73 countries flat at 78% • Campaigns still business as usual vs. focus on unreached & move to RI • IRC: Epidemiological analysis not sufficiently robust to inform planned activities; use of modelling
  • 26. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions 49% 72% Low polio3 coverage – risk to achieving & sustaining eradication Endemic country cVDPV type 2 WPV type 1 Board meeting 29-30 November 2017 60% Cases to date in 2017 Data source:GPEI; WUENIC 2016
  • 27. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions Niger: 67% Chad: 46% CAR: 47% Yemen: 71% Ethiopia: 77% Somalia: 47% South Sudan: 31% DR Congo: 79% Madagascar: 77% Syria: 42% 49% 60% 72% Endemic country cVDPV type 2 WPV type 1 Cases to date in 2017 Data source:GPEI; WUENIC 2016 Low polio3 coverage – risk to achieving & sustaining eradication Board meeting 29-30 November 2017
  • 28. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Polio Transition – no country yet to finalise their plan Previous Board decisions Board meeting, 29-30 November 2017
  • 29. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda August 2017 – first Gavi grant disbursement 2017 UNICEF progress report • Increased coverage • 31 Health Facilities reopened Board meeting 29-30 November 2017 Previous Board decisions Syria Unfortunately continued challenges • Outbreaks: cVDPV2 70 cases, Measles 7,000 cases • Cold chain & vaccine attack in al-Mayadin, near Deir al-Zor, Eastern Syria (October) – centre of polio outbreak • Loss of 100,000 measles, 35,000 polio doses & equipment
  • 30. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Yemen – Acute Humanitarian Crisis Board meeting 29-30 November 2017 Growing humanitarian crisis • >60% of people food insecure,>30% depend onfood aid • >50% need help to access drinkingwater and sanitation • ~50% of health facilities non-functional, >10M people lack accessto basic healthcare Ongoingoutbreaks • Cholera: ~950,000 cases. Waning but continued risk • Diphtheria:120 cases diagnosed,14 deaths. >1m children at risk Response • Partners working to deliver food,fuel & vaccines – 1.9M routine vaccine doses (mainly penta / PCV) arrived this week • WHO and UNICEF conducting outreach campaigns with Gavi support– constrained by access challenges and blockade Previous Board decisions Source: WHO Weekly Epidemiological Bulletin (21 November 2017),UN OCHA
  • 31. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions Cholera: affected countries, October 2017 Countries reporting cholera, 2010-2016 Countries reporting cholera, 2017 Somalia 77,783 cases Haiti 12,167 cases Yemen 945,362 cases South Sudan 21,530 cases DR Congo 42,334 cases Sudan 35,354 cases Nigeria 5,336 cases Ethiopia 47,711cases Board meeting 29-30 November 2017 Approved for Gavi vaccine support in 2017 Cameroon Malawi Mozambique Sierra Leone Source: WHO Cholera Update 17 Nov 2017
  • 32. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions Oral cholera vaccine: impact of our investment 0 2 4 6 8 10 12 14 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 Numberofdosesusedglobally(millions) Board meeting 29-30 November 2017 (to end October) Euvichol Shanchol Dukoral Shanchol prequalified Creation of stockpile/Gavi investment Euvichol prequalified Gavi support for operational costs 13,322,316 approved doses in 2017 to date, 17m by year end Next version of Euvichol • Less expensive • Ease of storage and transportation • Ease of administration and waste management
  • 33. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Ending Cholera Strategy Board meeting 29-30 November 2017 Previous Board decisions
  • 34. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda International Coordinating Group Board meeting 29-30 November 2017 Previous Board decisions • Board-approved support based on key principles • Stockpiles part of comprehensive disease strategy • Transparency & accountability in decision-making • Coherent,Alliance-wide forecastsand procurement • Decision criteria more transparent, information shared in real time & Gavi Secretariat observing ICG discussions • Independent evaluation recommendations • Formal governance structure with new oversight body • Clearer definition of roles and responsibilities • More standardised reporting • Continue to strengthen linkages with disease control strategies;create global strategy for meningitis control
  • 35. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Slow progress in implementing Eliminating Yellow Fever Epidemics strategy Mass preventive campaigns Ghana Nigeria Sudan DR Congo (application January 2018)  New applications for routine YF vaccination Ethiopia Sudan South Sudan Uganda Strengthened governance and accountability Global level governance structure has been formed Key working groups not yet operational         Board meeting 29-30 November 2017 Previous Board decisions 
  • 36. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Yellow Fever coverage stagnant, tracking below MCV1 given same time Board meeting 29-30 November 2017 0% 20% 40% 60% 80% 2008 2010 2012 2014 2016 YF coverage across 22 at-risk countries Chad – MCV1 and YF 0% 20% 40% 60% 80% 2008 2010 2012 2014 2016 Yellow Fever MCV1 Previous Board decisions
  • 37. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Nigeria yellow fever outbreak Board meeting 29-30 November 2017 States with confirmed cases States with suspected cases Main cities Coverage: 12.6% 67.5% 55.7% 12.2% 66.3% 50.8% 65.5% Source: NICS survey, Nigeria CDC Previous Board decisions • 179 suspected cases, 15 confirmed. 2 confirmed deaths • ICG approved a 960,000 doses in October and 1.4M doses in November for outbreak response • 61M doses approved for preventive campaign in 2012, only 12M shipped due to supply constraints
  • 38. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Campaigns & Routine Immunisation of Meningitis A vaccine have led to virtual elimination of disease 38 450 million people live in Africa’s “meningitis belt” across 26 countries >287m people vaccinated in 2010-2016 January - 2 July 2017 Niger Burkina Faso Mali 842 156 16 IMPACT: Number of meningitis A cases: in 2008 0 0 0 21out of 26 countries partially or totally vaccinatedby MenAfriVac Board meeting 29-30 November 2017 Sources: www.who.int/csr/disease/meningococcal/Bulletin_Meningite_S26_2017.pdf 2010–2016: >235mn (until Feb 2016) people vaccinated: http://immunizationinafrica2016.org/releases/2016/2/23/as-meningitis-nears; 4,069,239: target group for MenA - WHO administrative coverage JRF file - Ghana, Niger, Senegal, Sudan (2016) Previous Board decisions Nigeria • IRC approved 36m+ doses for catch-up campaign, 6m for routine • Majority of doses produced: risk of expiry if not used
  • 39. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaPrevious Board decisions Ebola Advanced Purchase Commitment with Merck VSV-EBOV for stockpile • Acceleratedreview timelines: - Priority Medicine scheme (EMA) - Breakthrough Therapy designation(FDA) • Submissionto be completed in 2018 • 300kinvestigative doses still available in the event of an outbreak SAGE working group to reconvene H1 2018 Board meeting 29-30 November 2017 Chinese approval for local Ad-5-EBOV vaccine • Chinese Academyof Military Medical Sciences’Bioengineering Institute & CanSino Biologics
  • 40. 3 Board meeting 29-30 November 2017 STRATEGIC ISSUES FOR DISCUSSION The importance of data to accelerate progress on coverage and equity
  • 41. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Above trend to immunise 300M children this period but challenges in reaching the fifth child Children immunisedwith DTP3/PENTA3 (Gavi68) DTP3/PENTA3 (Gavi68) 80%80%80%78% 68% 60% 2016 2001 2005 2015 2010 2014 MCV1 (Gavi68) 78%78%78%78% 68% 60% 2016 2015 2001 2005 2014 2010 2012 60.4M 2011 60.3M 2014 62.4M 2013 60.6M 2010 59.5M 2016 63.9M 2015 63.1M Board meeting 29-30 November 2017 Strategic questions for discussion WHO-UNICEF Estimatesof 2016 Immunisation Coverage (release July2017), UN Population Division (2017)
  • 42. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Challenges with WUENIC data – Pakistan example Board meeting 29-30 November 2017 WUENIC estimate unchanged since 2012 (72%) Coverage:Punjab 2012 DHS 2014 Punjab MICS 2016 Punjab Health Survey DTP3 62.5% 71.7% 85.2% MCV1 49.7% 71.6% 84.6% • Tremendous progress since 2012 • Population of Punjab represents nearly half of Pakistan Strategic questions for discussion
  • 43. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda What does this mean in reality? Challenges with WUENIC data Strategic questions for discussion Board meeting 29-30 November 2017 Congo Republic 73% 80% 73% 66% WUENIC Country Official Estimate MICS survey (preliminary) Adminis- trative 72% 61% 57% WUENIC Country Official Estimate Adminis- trative PNG WHO-UNICEF Estimatesof 2016 Immunisation Coverage (release July2017), UN Population Division (2017)
  • 44. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Data issue is broader than immunisation Board meeting 29-30 November 2017 Proportionof Gavi73 wherecoverage estimates are challengeddue to inconsistentpopulationdata Strategic questions for discussion +50% WUENIC Grade of Confidence defined: • Administrative coverage • Official coverage • Survey coverage • Population data All declining as drivers of uncertainty Largest (and growing) driver of uncertainty WHO-UNICEF Estimatesof 2016 Immunisation Coverage (release July2017), UN Population Division (2017)
  • 45. Our data journey Past How do we accelerate progress? Board meeting, 29-30 November 2017 Today Future vision • HSS not targeted and a “data-free zone” • Data investments limited and fragmented • Limited visibility on technical support • Light-touch Secretariat engagementwith countries • GPFs for every grant with intermediate HSS indicators • Data SFA: Joined up approach to data strengthening • PEF: Full transparency on TCA • New tools: Surveys every 5 years, data triangulation etc. • Enhanced dialogue: more SCMs, JointAppraisals using data etc. • Transformationin country data systems based on 21st century, digital technologies • Data available to all those who need it • Data used to track children & allow follow-up with parents
  • 46. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Triangulation critical to address data challenges – comparing shipment and consumption data in Ethiopia • Consumption algorithm aligns with WUENIC data • Admin data higher than doses available, highlighting issues in data system • Can support engagement on data quality 6M 4M 2M 0M 10M 8M 2018 est. 2017 est. 2016201520142013201220112010200920082007 Country: reporting number of doses used & requesting doses Dose need calculated from WUENIC Predicted consumption: Gavi algorithm (shipments, stock changes) Strategic questions for discussion Board meeting 29-30 November 2017 Pentavalentvaccine consumption,doses WHO-UNICEF Estimates of 2016 Immunisation Coverage (release July 2017) Country request and shipping data
  • 47. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Civil Society Organisations helping to strengthen data: Coverage survey in 3 Urban Slums, Punjab province Board meeting 29-30 November 2017 Many of the under-immunised are in slums vs rural areas Strategic questions for discussion
  • 48. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agendaStrategic questions for discussion ~27,000 facilities (95% sub-district) ~27M newborns ~30M pregnancies ~100M <5 years of age >650M doses >9M immunisation sessions Complex environment + Barriers to Digitalisation: • Access to • Electricity • Computers • Internet • Data entry operators How digital data is supporting the world’s largest immunisation programme
  • 49. HOW IT WORKS Geographic informationTemperature & Inventory information Temperature over timeState-based informationStock information
  • 50. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda 6002 1645 Pre-eVIN Post eVIN stockouts 72% Reduction 497 1405 880 241 241 518 68 106 464 1150 432 233 186 142 84 84 194 18 61 152 298 193 Pre-eVIN Post eVIN Stock Out Reduction – Post eVIN Board meeting, 29-30 November 2017 Strategic questions for discussion
  • 51. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda We are expanding our partnerships with innovative projects beyond data too Board meeting, 29-30 November 2017 Strategic questions for discussion Private Sector Partners Demand Generation Supply Chain Data Management CREATE “CLUSTERS” OF FIRMS THAT PROVIDE PROVEN SOLUTIONS & INNOVATIONS FROM WHICH COUNTRIES CAN SEEK SUPPORT
  • 52. 3 Board meeting 29-30 November 2017 STRATEGIC ISSUES FOR DISCUSSION Balancing sustainability and new vaccine introductions
  • 53. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Balancing sustainability & new vaccine introductions Board meeting 29-30 November 2017 Vietnam Angola Coverage (DTP3) 96% 64% Number of vaccines introduced 8 11 General government health expenditures as a proportion of general government expenditures (in 2014, the year with the most recent available data) 14.2% 5% Vaccines as % general health expenditure (projection at time of transition) 0.1% 1.2% Co-financing history Never defaulted Multiple defaults (2011, 2012, 2013, 2014 & 2015) Other Strong health system; want to introduce PCV & Rotavirus 2021-2025. High burden of disease including HPV. Applied once for HPV but turned down by IRC. Strategic questions for discussion
  • 54. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Board meeting 29-30 November 2017 • Introduction of new vaccines did not affect coverage of DTP3 vaccine in the countries studied • Of many scenarios tested, only one proved to be associated with changes in DTP3 and the direction was positive • Introductions of other new vaccines & multiple vaccine introductions should be monitored for immunisation and health systems impacts Effects of Vaccine introductions on RI Centre for Health Economics and Policy Analysis,The Bill and Melinda Gates Foundation,International Vaccine AccessCenter,published October 2012 Strategic questions for discussion
  • 55. 4 Board meeting 29-30 November 2017 ALLIANCE UPDATE
  • 56. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Alliance Health Survey Board meeting 29-30 November 2017 Activities underway: • Alliance directory for in-country and HQ colleagues • On boarding pack for new colleagues joining the alliance • IT solutions to share information • Across alliance get-togethers • Joint communication from leadership Follow-up survey Q1 2018 • UNICEF & WHO expanding to CDC & World Bank Alliance update
  • 57. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Civil Society Organisation – stronger engagement Board meeting 29-30 November 2017 Multiple initiatives to support communication and activities for increased CSO contribution to immunisation Alliance update
  • 58. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Board meeting 29-30 November 2017 Gavi People Survey Alliance update JUNE JULY SEPTEMBERAUGUST OCTOBER NOVEMBER DECEMBER 19 June 1-day Gavi Leadership Team offsite dedicated to GPS 23 June High-level results presentation to all staff GPS results roll- out to teams Discussions within each team to identify their priorities 13/14 Sept. Directors' 2-day meeting to discuss GPS results & define path forward 22 Sept. Special all staff in DC & Geneva, deep dive into results, identify key drivers of challenges & potential solutions 17 Nov. Senior Management Team all-day meeting Development of team and organisational action plans
  • 59. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Board meeting 29-30 November 2017 Alliance update Update on secretariat facilities, Washington
  • 60. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Board meeting 29-30 November 2017 Update on secretariat facilities, Geneva Global Health Campus October 2015 Start of construction February 2018 July 2018 Building handover March 2018 The Global Fund move Gavi move Alliance update
  • 61. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Operational efficiencies at Global Health Campus Board meeting 29-30 November 2017 Immediate efficiciencies - Rental savings - Facilities management - Security - Printing - IT network and communications To be worked on post-move - Travel management and security - IT service desk - Cyber security - IT engineering - Occupational health Opportunities for further exploration - Procurement services - IT software licenses and devices - Sharing certain IT systems - Aligning finance platforms Opportunity to improve services at reduced cost
  • 62. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Programmatic collaboration with the Global Fund Alliance update Joint advocacy at global and country level Coordinating programmatic investments Aligning and contributing to each other’s policies Board meeting, 29-30 November 2017 Knowledge sharing Joint advocacy at global and country level Coordinating programmatic investments Aligning and contributing to each other’s policies Board meeting, 29-30 November 2017
  • 63. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Programmatic collaboration with the Global Fund Alliance update Knowledge sharing Joint advocacy at global and country level Coordinating programmatic investments Aligning and contributing to each other’s policies Board meeting, 29-30 November 2017 • Gavi SCMs and GF counterparts regularly exchange country knowledge and intelligence • Governance teams regularly share best practice and lessons learned • Gavi shares fiduciary risk intelligence and unit cost information with GF • Aligning HSS investments where this can address common challenges (e.g. Burkina Faso, DRC, Ethiopia, Liberia, Nigeria, PNG Tanzania etc.) • Co-investing in strengthening data (e.g., data quality assessments in Cameroon, Chad, Malawi, Mali, etc.) • Shared fiduciary oversight and assurance mechanisms (e.g. DRC, Ghana, Kenya, Madagascar) • Joint missions to countries (e.g., Afghanistan, CAR, DRC, Eritrea, Guinea-Buissau, Niger, Nigeria) • Coordinating contribution to other global health initiatives (e.g., GFF Investors Group, PMNCH Board, UHC2030 Steering Committee). • GF was a member of the Steering Committees for the HSIS policy and Supply & Procurement Strategy • Gavi and GF collaborated closely on fragility policy review • Collaborated closely on developing operational guidelines (e.g., fragility, HR capacity and incentives, country team approaches) Knowledge sharing Joint advocacy at global and country level Coordinating programmatic investments Aligning and contributing to each other’s policies Board meeting, 29-30 November 2017
  • 64. 5 Board meeting 29-30 November 2017 BOARD AGENDA
  • 65. Key developments Previous Board decisions Strategic questions for discussion Alliance update Board agenda Ambitious agenda, important decisions Board meeting 29-30 November 2017 Board agenda • Financial forecast • Risk & Assurance Report • Partners’ Engagement Framework & budget • Typhoid containing vaccine support • Country programmes & strategic issues • Vaccine Investment Strategy • Country engagement post-transition • Nigeria & PNG strategies 25% reduction in length of Board pack Investment trade-off framework