This document discusses a natural testosterone formula that contains several herbal extracts that support testosterone production and male and female sexual function. It contains Muira puama, horny goat weed, velvet bean extract, gokhru fruit extract, tongkat ali, and panax ginseng root extract. Each of these ingredients has been shown to increase testosterone levels, support the hypothalamus-pituitary-gonadal axis, decrease cortisol levels, and improve sexual function and libido in both men and women. The formula aims to boost the body's natural testosterone production through these various herbal mechanisms.
The document summarizes endocrine functions of the testes. It discusses hormones secreted by the testes including testosterone and its role in male puberty and development. It describes the hypothalamic-pituitary-testicular axis that regulates testosterone production and discusses conditions like hypogonadism that can result from dysfunction of this axis. Specifically, it contrasts primary and secondary hypogonadism and their causes like Klinefelter's syndrome or Kallman's syndrome.
This document discusses the major sex hormones estrogen, progesterone, and testosterone. It describes their roles and importance in the male and female bodies, including mediating sexual development and characteristics. The modes of action, physiological effects, potential pathologies associated with high and low levels, diseases related to hormone imbalance, and normal ranges are outlined for each hormone.
Points:
Male Sex Hormone - Androgens (Mainly Testosterone)
Synthesis, Regulation & metabolism (By both Hypothalamus & Pituitory gland)
Various Action/ Physiological roles over:
1. Sex organs and secondary sex characters (Androgenic)
2. Testes
3. Skeleton and skeletal muscles (Anabolic)
4. Erythropoiesis
Anabolic Steroids & their uses
Antiandrogens (Classification, MOA & Uses)
Drugs for erectile dysfunction (MOA & Uses)
Main Male Sex Hormone is Testosterone which converts into its highly active form i.e. dihydrotestosteron (DHT).
Main Female Sex Hormones are Estrogen & Progesterone.
PH1.37 Describe the mechanism of action, types, doses, side effects, indications and contraindications of the drugs used as sex hormones, their analogues
This document provides an overview of primary and secondary hypogonadism. It defines hypogonadism as insufficient sex hormone production, outlines the two types (primary affecting the gonads, secondary affecting the pituitary gland), and describes their causes, symptoms, investigations and treatments for both males and females. Primary hypogonadism results from gonad dysfunction, while secondary is due to problems with the hypothalamus or pituitary gland impairing gonad stimulation. Treatment aims to restore hormone balance through replacement therapies, address underlying issues, and support overall health.
Anabolic steroids mimic the effects of testosterone in the body. By taking supraphysiological doses, it disrupts the body's natural production of testosterone through a negative feedback loop. This can lead to infertility and other side effects by interfering with the hypothalamic-pituitary-gonadal axis. The high levels of steroids also put stress on organs like the liver and can increase risks of certain cancers. The mood and behavioral changes are also side effects of the unnatural hormone fluctuations.
The document summarizes endocrine functions of the testes. It discusses hormones secreted by the testes including testosterone and its role in male puberty and development. It describes the hypothalamic-pituitary-testicular axis that regulates testosterone production and discusses conditions like hypogonadism that can result from dysfunction of this axis. Specifically, it contrasts primary and secondary hypogonadism and their causes like Klinefelter's syndrome or Kallman's syndrome.
This document discusses the major sex hormones estrogen, progesterone, and testosterone. It describes their roles and importance in the male and female bodies, including mediating sexual development and characteristics. The modes of action, physiological effects, potential pathologies associated with high and low levels, diseases related to hormone imbalance, and normal ranges are outlined for each hormone.
Points:
Male Sex Hormone - Androgens (Mainly Testosterone)
Synthesis, Regulation & metabolism (By both Hypothalamus & Pituitory gland)
Various Action/ Physiological roles over:
1. Sex organs and secondary sex characters (Androgenic)
2. Testes
3. Skeleton and skeletal muscles (Anabolic)
4. Erythropoiesis
Anabolic Steroids & their uses
Antiandrogens (Classification, MOA & Uses)
Drugs for erectile dysfunction (MOA & Uses)
Main Male Sex Hormone is Testosterone which converts into its highly active form i.e. dihydrotestosteron (DHT).
Main Female Sex Hormones are Estrogen & Progesterone.
PH1.37 Describe the mechanism of action, types, doses, side effects, indications and contraindications of the drugs used as sex hormones, their analogues
This document provides an overview of primary and secondary hypogonadism. It defines hypogonadism as insufficient sex hormone production, outlines the two types (primary affecting the gonads, secondary affecting the pituitary gland), and describes their causes, symptoms, investigations and treatments for both males and females. Primary hypogonadism results from gonad dysfunction, while secondary is due to problems with the hypothalamus or pituitary gland impairing gonad stimulation. Treatment aims to restore hormone balance through replacement therapies, address underlying issues, and support overall health.
Anabolic steroids mimic the effects of testosterone in the body. By taking supraphysiological doses, it disrupts the body's natural production of testosterone through a negative feedback loop. This can lead to infertility and other side effects by interfering with the hypothalamic-pituitary-gonadal axis. The high levels of steroids also put stress on organs like the liver and can increase risks of certain cancers. The mood and behavioral changes are also side effects of the unnatural hormone fluctuations.
Androgens such as testosterone are responsible for male sexual development. Testosterone is produced in the testes and regulated by LH and FSH. It has pharmacological actions via the androgen receptor and is metabolized in the liver. Therapeutic uses include androgen replacement therapy. Anabolic steroids have similar effects but higher anabolic to androgenic ratios. Antiandrogens like danazol and flutamide work by blocking androgen receptors. PDE5 inhibitors like sildenafil are used to treat erectile dysfunction by increasing nitric oxide signaling.
Androgens are like sculptors, chiseling out male features during puberty. From the deepening voice to the growth of facial hair, they conduct the symphony of manhood.
But androgens aren't one-trick ponies exclamation They influence bone strength, sex drive, and even red blood cell production in both men and women expand more. Think of them as the invisible architects of our bodies, with a surprising influence beyond masculinity.
1. The document discusses androgens and their role in male physiology and pharmacology. It describes hormones like testosterone and their effects on tissues like the testes, prostate, and muscles.
2. Various androgen therapies are mentioned for conditions like hypogonadism, breast cancer, and osteoporosis. Antiandrogen drugs are also summarized that block androgen receptors for prostate cancer.
3. Biosynthesis and metabolism of testosterone is outlined. Side effects of androgen therapies and indications for antiandrogens are provided. Erectile dysfunction treatments like sildenafil are also briefly described.
Testicular hormones, such as testosterone and inhibin, provide negative feedback regulation of gonadotropin secretion in males. Testosterone secretion by Leydig cells is stimulated by LH and testosterone then inhibits both LH and FSH secretion. Inhibin, produced by Sertoli cells, further suppresses FSH levels through actions at the pituitary. This negative feedback loop regulates the hypothalamic-pituitary-testicular axis in males.
This document discusses hormonal replacement therapy (HRT). It begins by defining HRT as any medical treatment that replaces hormones the body can no longer produce on its own due to age or organ damage/failure. The main types of HRT are then listed, including various sex hormones. Effects of HRT for transgender individuals and testosterone replacement therapy are also outlined. The document concludes by discussing menopause, including its phases, causes, and physiological changes like hormonal and ovarian changes.
Medicinal Chemistry of Steroidal Harmons
Classification of Steroidal Harmons
Medicinal Uses
Biosynthesis of Steroidal Harmons
Mechanism of action of Steroidal Harmons
Natural and Synthetic derivatives of Steroidal Harmons and their Inhibitors
This document provides information on hormones, hormonal disorders, and their treatment. It discusses various glands of the endocrine system and the hormones they produce, including the pituitary, thyroid, parathyroid, adrenals, ovaries, testes, and pineal gland. It then covers several hormonal disorders - growth hormone excess and deficiency affecting the pituitary; thyroid disorders; adrenal disorders like Cushing's and Addison's disease; diabetes insipidus; prolactinoma; and menopause. For each, it discusses symptoms, investigations, and homeopathic and conventional treatment approaches. The document emphasizes managing hormonal disorders and related symptoms using diet, lifestyle changes, hormone therapy when needed, and homeopathic medicines
This document discusses reproductive hormones. It defines reproductive hormones as those responsible for sexual development, libido, and menstruation. It describes the hypothalamic-pituitary-gonadal axis that controls hormone production and can cause issues if dysfunctional. It outlines the roles of FSH, LH, testosterone, estrogen, and progesterone in the male and female reproductive systems and menstrual/estrous cycles. Finally, it discusses some health impacts of reproductive hormones like osteoporosis, heart disease, infertility, and mood changes.
This document discusses the hormonal control of the male and female reproductive systems. It provides details on:
- The main hormones involved (testosterone, estrogen, progesterone) and their sites of production and mechanisms of action
- Clinical uses of hormones and hormone therapies, including contraception and hormone replacement therapies
- Potential side effects of hormone administration, such as masculinization, fluid retention, risk of blood clots, and impaired growth in children
This document provides an overview of the endocrine system and how it coordinates and regulates various bodily functions through the secretion of hormones. It describes the major endocrine glands like the hypothalamus, pituitary gland, thyroid gland, parathyroid glands, adrenal glands, pancreas, gonads, and others. It also discusses the characteristics, classifications, functions, and mechanisms of action of different hormones. Disorders that can occur due to hormonal imbalances are also mentioned.
Androgens like testosterone are responsible for male sexual characteristics. Testosterone is produced primarily in the testes and stimulates the development of male sex organs and secondary sex characteristics at puberty. It also has anabolic effects like promoting muscle and bone growth. Anti-androgens can inhibit androgen production or block their effects, and are used to treat conditions like prostate cancer and excess hair growth in women. Common side effects of androgens and anti-androgens include sexual dysfunction and breast changes.
This document discusses how hormones change with aging and menopause. It notes that hormones are produced by various organs and tissues in the body, including the hypothalamus, pituitary gland, thyroid, parathyroid glands, pancreas, adrenal glands, kidneys, ovaries, and testes. These hormones decline with aging, which can affect functions like metabolism, bone health, blood glucose, and sex hormone levels. Symptoms of menopause like hot flashes and sleep issues are also discussed, as well as factors that affect the onset of menopause and treatment options. Depression is another common issue related to changing hormone levels during menopause.
This document discusses sex hormones, including estrogens, progesterone, antiestrogens, and antiprogestins. It provides details on the natural and synthetic forms of estrogens and progesterone, their receptors, mechanisms of action, regulation, and uses. The key points are:
- Estrogens and progesterone are secreted by the ovaries and play important roles in the female reproductive system and other body processes.
- They act through nuclear receptors and genomic/nongenomic signaling pathways to regulate gene expression.
- Selective estrogen receptor modulators (SERMs) can act as agonists or antagonists depending on the tissue.
- Progestins and antiestrogens/antiprogestins are
The document summarizes the structure and function of the anterior pituitary gland and its relationship to the hypothalamus. It discusses the following key points:
- The anterior pituitary secretes 6 hormones (GH, ACTH, TSH, Prolactin, FSH, LH) which control various target glands and metabolic functions.
- The hypothalamus controls anterior pituitary secretion through releasing and inhibitory hormones transported via a portal system. These include TRH, GnRH, CRH, GHRH, and dopamine.
- Disorders of the anterior pituitary can cause gigantism/acromegaly from hypersecretion or dwarfism from hyposecretion of growth hormone.
The endocrine system regulates important body functions through hormones secreted by various glands. Key glands include the adrenal glands, ovaries, testes, pancreas, parathyroid and thyroid glands, pineal gland, and pituitary gland. These glands secrete hormones that regulate metabolism, growth and development, tissue function, sexual function, reproduction, sleep cycles, and other critical processes. Disorders of the endocrine system can affect hormone levels and the function of glands like the thyroid, leading to diseases such as diabetes, osteoporosis, infertility, and other conditions.
This document discusses the roles and functions of androgens and estrogens in the male and female body. It describes how androgens and estrogens contribute to sexual development and function, their clinical uses, and potential side effects of hormone therapy. The summary also outlines the menstrual cycle and the roles of various hormones like FSH, LH, estrogen, and progesterone in regulating the female reproductive cycle.
Androgens are male sex hormones that cause the development of secondary sex characteristics in males. The primary androgen is testosterone, which is produced in the testes and regulated by LH from the pituitary gland. Testosterone promotes the growth of male sex organs and secondary sex characteristics at puberty such as facial and body hair growth, deepening of the voice, and increased muscle and bone growth. It works by binding to androgen receptors and enhancing protein synthesis. Common androgen preparations are used to treat conditions like testicular failure, aging-related low testosterone, and erectile dysfunction. Phosphodiesterase type 5 inhibitors like sildenafil are a treatment for erectile dysfunction by enhancing the effects of nitric oxide
Androgens such as testosterone are responsible for male sexual development. Testosterone is produced in the testes and regulated by LH and FSH. It has pharmacological actions via the androgen receptor and is metabolized in the liver. Therapeutic uses include androgen replacement therapy. Anabolic steroids have similar effects but higher anabolic to androgenic ratios. Antiandrogens like danazol and flutamide work by blocking androgen receptors. PDE5 inhibitors like sildenafil are used to treat erectile dysfunction by increasing nitric oxide signaling.
Androgens are like sculptors, chiseling out male features during puberty. From the deepening voice to the growth of facial hair, they conduct the symphony of manhood.
But androgens aren't one-trick ponies exclamation They influence bone strength, sex drive, and even red blood cell production in both men and women expand more. Think of them as the invisible architects of our bodies, with a surprising influence beyond masculinity.
1. The document discusses androgens and their role in male physiology and pharmacology. It describes hormones like testosterone and their effects on tissues like the testes, prostate, and muscles.
2. Various androgen therapies are mentioned for conditions like hypogonadism, breast cancer, and osteoporosis. Antiandrogen drugs are also summarized that block androgen receptors for prostate cancer.
3. Biosynthesis and metabolism of testosterone is outlined. Side effects of androgen therapies and indications for antiandrogens are provided. Erectile dysfunction treatments like sildenafil are also briefly described.
Testicular hormones, such as testosterone and inhibin, provide negative feedback regulation of gonadotropin secretion in males. Testosterone secretion by Leydig cells is stimulated by LH and testosterone then inhibits both LH and FSH secretion. Inhibin, produced by Sertoli cells, further suppresses FSH levels through actions at the pituitary. This negative feedback loop regulates the hypothalamic-pituitary-testicular axis in males.
This document discusses hormonal replacement therapy (HRT). It begins by defining HRT as any medical treatment that replaces hormones the body can no longer produce on its own due to age or organ damage/failure. The main types of HRT are then listed, including various sex hormones. Effects of HRT for transgender individuals and testosterone replacement therapy are also outlined. The document concludes by discussing menopause, including its phases, causes, and physiological changes like hormonal and ovarian changes.
Medicinal Chemistry of Steroidal Harmons
Classification of Steroidal Harmons
Medicinal Uses
Biosynthesis of Steroidal Harmons
Mechanism of action of Steroidal Harmons
Natural and Synthetic derivatives of Steroidal Harmons and their Inhibitors
This document provides information on hormones, hormonal disorders, and their treatment. It discusses various glands of the endocrine system and the hormones they produce, including the pituitary, thyroid, parathyroid, adrenals, ovaries, testes, and pineal gland. It then covers several hormonal disorders - growth hormone excess and deficiency affecting the pituitary; thyroid disorders; adrenal disorders like Cushing's and Addison's disease; diabetes insipidus; prolactinoma; and menopause. For each, it discusses symptoms, investigations, and homeopathic and conventional treatment approaches. The document emphasizes managing hormonal disorders and related symptoms using diet, lifestyle changes, hormone therapy when needed, and homeopathic medicines
This document discusses reproductive hormones. It defines reproductive hormones as those responsible for sexual development, libido, and menstruation. It describes the hypothalamic-pituitary-gonadal axis that controls hormone production and can cause issues if dysfunctional. It outlines the roles of FSH, LH, testosterone, estrogen, and progesterone in the male and female reproductive systems and menstrual/estrous cycles. Finally, it discusses some health impacts of reproductive hormones like osteoporosis, heart disease, infertility, and mood changes.
This document discusses the hormonal control of the male and female reproductive systems. It provides details on:
- The main hormones involved (testosterone, estrogen, progesterone) and their sites of production and mechanisms of action
- Clinical uses of hormones and hormone therapies, including contraception and hormone replacement therapies
- Potential side effects of hormone administration, such as masculinization, fluid retention, risk of blood clots, and impaired growth in children
This document provides an overview of the endocrine system and how it coordinates and regulates various bodily functions through the secretion of hormones. It describes the major endocrine glands like the hypothalamus, pituitary gland, thyroid gland, parathyroid glands, adrenal glands, pancreas, gonads, and others. It also discusses the characteristics, classifications, functions, and mechanisms of action of different hormones. Disorders that can occur due to hormonal imbalances are also mentioned.
Androgens like testosterone are responsible for male sexual characteristics. Testosterone is produced primarily in the testes and stimulates the development of male sex organs and secondary sex characteristics at puberty. It also has anabolic effects like promoting muscle and bone growth. Anti-androgens can inhibit androgen production or block their effects, and are used to treat conditions like prostate cancer and excess hair growth in women. Common side effects of androgens and anti-androgens include sexual dysfunction and breast changes.
This document discusses how hormones change with aging and menopause. It notes that hormones are produced by various organs and tissues in the body, including the hypothalamus, pituitary gland, thyroid, parathyroid glands, pancreas, adrenal glands, kidneys, ovaries, and testes. These hormones decline with aging, which can affect functions like metabolism, bone health, blood glucose, and sex hormone levels. Symptoms of menopause like hot flashes and sleep issues are also discussed, as well as factors that affect the onset of menopause and treatment options. Depression is another common issue related to changing hormone levels during menopause.
This document discusses sex hormones, including estrogens, progesterone, antiestrogens, and antiprogestins. It provides details on the natural and synthetic forms of estrogens and progesterone, their receptors, mechanisms of action, regulation, and uses. The key points are:
- Estrogens and progesterone are secreted by the ovaries and play important roles in the female reproductive system and other body processes.
- They act through nuclear receptors and genomic/nongenomic signaling pathways to regulate gene expression.
- Selective estrogen receptor modulators (SERMs) can act as agonists or antagonists depending on the tissue.
- Progestins and antiestrogens/antiprogestins are
The document summarizes the structure and function of the anterior pituitary gland and its relationship to the hypothalamus. It discusses the following key points:
- The anterior pituitary secretes 6 hormones (GH, ACTH, TSH, Prolactin, FSH, LH) which control various target glands and metabolic functions.
- The hypothalamus controls anterior pituitary secretion through releasing and inhibitory hormones transported via a portal system. These include TRH, GnRH, CRH, GHRH, and dopamine.
- Disorders of the anterior pituitary can cause gigantism/acromegaly from hypersecretion or dwarfism from hyposecretion of growth hormone.
The endocrine system regulates important body functions through hormones secreted by various glands. Key glands include the adrenal glands, ovaries, testes, pancreas, parathyroid and thyroid glands, pineal gland, and pituitary gland. These glands secrete hormones that regulate metabolism, growth and development, tissue function, sexual function, reproduction, sleep cycles, and other critical processes. Disorders of the endocrine system can affect hormone levels and the function of glands like the thyroid, leading to diseases such as diabetes, osteoporosis, infertility, and other conditions.
This document discusses the roles and functions of androgens and estrogens in the male and female body. It describes how androgens and estrogens contribute to sexual development and function, their clinical uses, and potential side effects of hormone therapy. The summary also outlines the menstrual cycle and the roles of various hormones like FSH, LH, estrogen, and progesterone in regulating the female reproductive cycle.
Androgens are male sex hormones that cause the development of secondary sex characteristics in males. The primary androgen is testosterone, which is produced in the testes and regulated by LH from the pituitary gland. Testosterone promotes the growth of male sex organs and secondary sex characteristics at puberty such as facial and body hair growth, deepening of the voice, and increased muscle and bone growth. It works by binding to androgen receptors and enhancing protein synthesis. Common androgen preparations are used to treat conditions like testicular failure, aging-related low testosterone, and erectile dysfunction. Phosphodiesterase type 5 inhibitors like sildenafil are a treatment for erectile dysfunction by enhancing the effects of nitric oxide
Best Digital Marketing Strategy Build Your Online Presence 2024.pptxpavankumarpayexelsol
This presentation provides a comprehensive guide to the best digital marketing strategies for 2024, focusing on enhancing your online presence. Key topics include understanding and targeting your audience, building a user-friendly and mobile-responsive website, leveraging the power of social media platforms, optimizing content for search engines, and using email marketing to foster direct engagement. By adopting these strategies, you can increase brand visibility, drive traffic, generate leads, and ultimately boost sales, ensuring your business thrives in the competitive digital landscape.
NHL Stenden University of Applied Sciences Diploma Degree Transcript
Cenegenics Testosterone Brochure
1. from Cenegenics® Medical Institute... The Global Leader in a proactive medical approach to optimized health
NATURAL
TESTOSTERONE
FORMULA
supports the production of testosterone
2. Natural Testosterone Formula | Call 480.454.2370 to order!
2
Introducing our all new Natural Testosterone
Formula
GONADROTROPHIC FUNCTION IN MEN In men, LH stimulates the Leydig cells in the testes to produce
testosterone. FSH stimulates Sertoli cells in the testes for production of spermatozoa in the seminiferous tubules of the
testes. Gonadotrophic hormone levels may be lower in men with chronic illness, as an undesirable affect of aging, in
men with hyperprolactinemia, and hypothalamic-pituitary disorders. Low levels have also been noted in obesity and
starvation.
GONADROTROPHIC FUNCTION IN WOMEN In women, LH stimulates the theta cells in the ovaries to produce
androgens and hormonal precursors for estradiol production. An LH surge triggers ovulation. FSH initiates follicular
growth specificullary stimulating granulosa cells to convert androgens (coming from thecal cells) to estratdiol by
aromatase during the follicular phase of the menstral cycle. Gonadotrophic hormone levels may be lower in women
with chronic illness, as an undesirable affect of aging, in women with hyperprolactinemia, and hypothalamicpituitary
disorders. Low levels have also been noted in obesity and starvation.
GENERALIZED PHYSICAL
• Decreased Lean Tissue
• Decreased Muscle Size
• Increased Body Fat
• Weight Gain
• Joint & Back Pain
• Skin has Decreased Firmness
or Fullness
• Headaches
• Anemia
SLEEP SYMPTOMS
• Insomnia
• Difficulty Falling to Sleep
• Difficulty Staying Asleep
• Night Sweats (in both men
and women)
ENERGY & STRENGTH
SYMPTOMS
• Tired & Fatigue
• Feel Weaker
• Decreased Endurance
GENERAL SYMPTOMS OF HYPOGONADISM
3. Natural Testosterone Formula | Call 480.454.2370 to order! 3
COGNITIVE SYMPTOMS
• Decreased Mental Skills
• Decreased Memory Function
• Can’t Solve Problems
• Can’t Focus Attention
• Can’t Remember Events
• Easily Confused
MOOD & BEHAVIORAL SYMPTOMS
• Depression
• Social Isolation
• Less Motivated
• Irritability
• Mood Changes
Neuro-Cognitive Symptoms of Low
Testosterone
SEXUAL SYMPTOMS
• Decreased Libido
• Diminished Orgasm
• Anorgasmia
• Pubic hair Thinning
ADDITIONAL MALE
SYMPTOMS & RISKS
• Risk for Insulin Resistance
• Erectile Dysfunction
• Risk for Heart Disease
• Sleep Apnea
ADDITIONAL FEMALE
SYMPTOMS & RISKS
• Vaginal Atrophy
• Pain with Intercourse
• Urinary Incontinence
• Vulvodynia
Sexual Symptoms of Low Testosterone
Low Testosterone Desired Therapeutic
Outcomes
• Increased
Testosterone
Production
• Increased action of
HPG Axis
• Increased
Testosterone Levels
• Increased Sexual
Function in men
• Increased Sexual
Function in women
• Increased Nitric Oxide
• Increased Anabolic
Activity
• Decreased Excessive
Cortisol activity
• Decreased Prolactin
levels
• Increased
Gonadotrophic
activity (FSH &/or LH)
• Increased Male
Reproductive ability
• Increased Female
Reproductive ability
4. Natural Testosterone Formula | Call 480.454.2370 to order!
4
How to Make your Own Testosterone
• By controlling negative/diminishing factors you can increase production of testosterone.
• While testosterone is anabolic, and builds muscle, cortisol is catabolic and breaks down muscle. In both male
and female athletes lower testosterone with a relatively higher cortisol results in an anabolic/catabolic hormone
imbalance adversely affect sports activity, and increase the risk of recurrent muscle injury.
• Long term stress results in increased production of cortisol and decreased production of testosterone—hormone
production shunts towards making cortisol and away from making testosterone.
ADAPTOGENS
• A number of herbs that can increase testosterone or have documented anabolic actions also help the body adapt
to stress and decrease the stress associated rise in cortisol. These plants are appropriately called “adaptogens”.
• A number of herbs actually have cortisol antagonist properties, which can counteract the negative consequences of
excessive cortisol. By controlling excessive cortisol, it can support a healthy production of testosterone – and allow
it to function optimally.
Call Cenegenics now to find out more about
our Natural Testosterone Formula.
480.454.2370
5. Natural Testosterone Formula | Call 480.454.2370 to order! 5
Ingredients THE HIGHEST QUALITY
MUIRA PUAMA (PTYCHOPETALUM
OLACOIDES) Muira puama is reputed to enhance erectile function
and orgasm in aging men suffering the effects of fatigue or age-related
complaints. Muira Puama has adaptogen properties (anti-stress, memory
enhancement, increased physical and/or sexual performance). Prevents
stress induced increase of corticosterone, indicating glucocorticoid
antagonist properties, which may contribute to a relative increase in
anabolic function. Traditionally used treating various age-related conditions,
Muira Puama is prized as a nerve tonic that facilitates memory retrieval and
improves cognitive function, due to both both antioxidant properties and
acetylcholinesterase inhibitory properties, which preserving acetylcholine
levels. The enhanced acetylcholine is another mechanism of improved
sexual function. Acetylcholine, as a parasympathetic neurotransmitter,
enhances sexual response in both genders by promoting relaxation of
penile cavernous smooth muscle or clitoral cavernous smooth muscle to
support penile erection or clitoral engorgement.
HORNY GOAT WEED EXTRACT (EPIMEDIUM
SAGITTATU) Sagittatum promotes testosterone production
through the action of icariin, a flavonol that improves the condition of
reproductive organs and increased the circulating levels of testosterone
in animal studies. Icariin has phosphodiesterase-5 (PDE5) inhibitor action
affecting all three PDE5 isoforms. The long history of use for treating erectile
dysfunction in Traditional Chinese Medicine (TCM) may be attributed to the
PDE5 inhibitor actions. PDE5 inhibitors can potentiate the sexual response
in both men and women. The sexual potentiation effect and improved the
quality of life was even seen in patients with chronic disease. Researchers
have also described icariin as having “testosterone mimetic properties” with
therapeutic potential for the management of hypoandrogenism. Epimedium
also has glucocorticoid antagonist properties, which may contribute to a
relative increase in anabolic function.
VELVET BEAN EXTRACT (MUCANA
PRURIENS) Promotes testosterone production in humans by its
action on the hypothalamus-pituitary-gonadal axis, and raises serum levels
of both testosterone and LH. Semen quality and sperm concentrations
are improved in infertile men. Animal studies confirm that Mucuna causes
a significant improvement in sexual behavior, libido and potency, sperm
parameters, and testosterone and LH levels, as well as reproductive organs
in females. Mucuna also decreases prolactin levels, which is significant
because hyperprolactinemia is a major neuroendocrine-related cause of
reproductive disturbances in both men and women. Significant increase
of sexual behavior through enhanced libido has been attributed to
L-dopa, the constituent in Mucuna that suppresses excessive prolactin.
Mucuna pruriens also has a normalizing affect on blood sugar, with some
researchers concluding that it can be used in diabetesinduced erectile
dysfunction.
GOKHRU FRUIT EXTRACT (TRIBULUS
TERRESTRIS) The concentration of blood testosterone increased
statistically within 10 days in athletes consuming Tribulus. Tribulus
terrestris increases testosterone, dihydrotestosterone (DHT) and
dehydroepiandrosterone sulphate in primates. Chronic administration of
Tribulus terrestris produced a significant increase in serum testosterone
levels and sexual behavior with no significant effect on the sperm count, and
no overt body system dysfunctions were observed in 28-day oral toxicity
study in animal studies published January 2012. The ability of Tribulus
terrestris to increase the release of nitric oxide from the endothelium and
nitrergic nerve endings, may account for its claims as an aphrodisiac in both
genders. Tribulus terrestris appears to have a gonadotropin-like activity that
can increase the number of corpora lutea, primary and secondary follicles
while significantly decreasing the number of ovarian cysts.
6. Natural Testosterone Formula | Call 480.454.2370 to order!
6
Ingredients THE HIGHEST QUALITY
TONGKAT ALI (EURYCOMA LONGIFOLIA)
Promotes testosterone production with a significant increase of plasma
testosterone level noted in animal studies. Human studies showed similar
results, with increases in serum testosterone levels. The men in the study
also had less symptoms of hypogonadism. One group of researchers
proposed that the proandrogenic effects of Eurycoma longifolia have can
be used as an alternative treatment to prevent and treat male osteoporosis
without causing the side effects associated with testosterone replacement
therapy. A number of animal studies validate the usefulness of Eurycoma
longifolia for androgen-deficient osteoporosis, with some researchers
recommending that Eurycoma longifolia may be used in combination with
low-dose testosterone in androgen-deficient osteoporosis. Eurycoma
longifolia also has anti-estrogen properties and can reverse the effects of
estrogen, which allows testosterone to work more effectively.
PANS GINSENG ROOT EXTRACT (PANAX
GINSENG) Male patients treated with Panax ginseng showed an
increase in spermatozoa number/ml and progressive oscillating motility,
an increase in plasma total and free testosterone, DHT, FSH and LH levels,
and a decrease in PRL. However, following acute resistance exercise, Panax
does not cause a rise in hormones levels, and does not to promote an
anabolic hormonal status when taken immediately following resistance
exercise. Panax Ginseng can mimic actions of testosterone associated with
the increase in both sexual desire and sexual function. Various human
studies demonstrate that Panax ginseng is effective for treating male
erectile dysfunction. In addition, Panax ginseng improved sexual arousal in
menopausal women and caused significant improvement in the Kupperman
index and the Menopause Rating Scale, indicating that Panax ginseng might
be used in menopausal women to improve their sexual life. Panax ginseng
inhibited testosterone-induced cell proliferation in both animal studies and
human prostate cells, indicating that Panax may decrease risks of prostate
disorders in men receiving testosterone replacement therapy.
ELEUTHEROCOCCUS SENTICOSOSUS ROOT
EXTRACT (ELEUTHEROCOCCUS SENTICOSUS)
Best described as a functional mimetic of testosterone in that it mimics
a significant number of testosterone functions including enhanced
endurance capacity, elevated cardiovascular function, metabolism altered
for sparing glycogen, as well as improvement of sperm motility. It also has
an anti-fatigue action, enhances recovery of stress induced NK activity
and inhibits stress induced corticosterone elevation. Like testosterone,
it is protective against the glucocorticoids induced osteoporosis. It has
significant adaptogen properties, with the ability to increase a nonspecific
body resistance to stress, fatigue, and disease. Like testosterone, it can also
increase endothelial nitric oxide levels, which can contribute to improved
sexual function in both genders.
ASHWAGANDHA ROOT EXTRACT (WITHANIA
SOMINFERA) Promotes testosterone production, and caused
significant increases in serum testosterone and luteinizing hormone in
men with a history of infertility. Those men also developed improved
sperm count and motility. Collectively, the research indicates that Withania
improves gonadal function in both genders. However, Withania suppresses
estrogen receptor-alpha function, promotes apoptosis, and inhibits growth
of MCF-7, and MDA-MB-231 human breast cancer cells. None-the-less,
Withania demonstrates anti-osteoporotic activity. Withania also mimics a
significant number of testosterone functions including adaptogenic with
increased stress tolerance, increased nitric oxide production, and increased
dopaminergic activity, and cardioprotection.
7. Natural Testosterone Formula | Call 480.454.2370 to order! 7
Ingredients THE HIGHEST QUALITY
MACA ROOT (LEPIDIUM MEYENII) Is a potent
testosterone mimetic that improves sexual function in both men and
women independent of testosterone or estrogen activity. Lepidium also
enhances female fertility in mice, spermatogenesis in male mice following
spermatogenic damage, and increases both the semen volume and sperm
motility in men. As a cruciferous vegetable, Lepidium meyenii may provides
benefits associated with consumption of cruciferous vegetables, such as a
reduced risk of prostate cancer. Maca reduced prostate size after 14 days
in animal studies, and prevented the prostate weight increase induced by
testosterone enanthate treatment, suggesting that Maca may decrease risks
of prostate disorders in men receiving testosterone replacement therapy.
DAMIANA LEAF (TERNERA DIFFUSA) Can
mimic functions of testosterone and act as a sexual stimulant, enhance
engorgement of erectile tissue due to its vasodilatory abilities, and
significantly reduce the post-ejaculatory interval. These effects were not
associated to an increase in locomotor activity or anxiety-like behaviors,
suggesting that the anxiolytic flavone apigenin may participate in its pro-
sexual effect. The testosterone mimetic effects are also considered as part
of a general adaptogen effect of Turnera diffusa.
Specific Actions
Herbal Ingredient
Adaptogenic
Androgenic
Testosterone
Production
Anabolic
Decrease
Excessive
Cortisol
Dopaminergic
–
lower
PRL
Nitric
Oxide
Enhancer
Antioxidant
Antiproliferative
Nootropic
Neuroprotect
Testosterone
Mimetic
Increased
Sexual
Desire
Improve
Sexula
Function
Ptychopetalum olacoides X X X X X X X X X X X
Epimedium sagittatum X X X X X X X X X
Mucuna pruriens X X X X X X X X X X X
Tribulus terrestris X X X X X X X X X
Eurycoma longifolia X X X X X X X X
Panax ginseng X X X X X X X X X X
Eleutherococcus senticosus X X X X X
Withania somnifera X X X X X X X X X
Lepidium meyenii X X X X X X X X X
Turnera diffus X X X X X
8. Natural Testosterone Formula | Call 480.454.2370 to order!
8
HERBAL FUNCTIONS
• Six of the herbs directly increase Testosterone production by the gonads
• Five of the herbs are documented to increase the actions of HPG Axis
• Six of the herbs are documented to increases Testosterone levels
• Three of the herbs Decreases Prolactin levels (remember, high prolactin suppresses FSH & LH)
• Five of the herbs increase Gonadotrophic levels (FSH &/or LH)
• Six of the herbs Increases Male Reproductive ability
• Three of the herbs Increases Female Reproductive ability
HERBAL SYNERGY
• Restoring the optimal function of testosterone is achieved by formulating the herbs so that the ultimate benefit is
derived from the combination.
• The herbs are formulated in such a way that they intensify and balance the action of the other herbs.
• The working together of the anabolic activities of some herbs with the abilities of other herbs to control excessive
cortisol. This control of excessive cortisol is important because high cortisol levels interfere with anabolic activity.
NATURAL TESTOSTERONE FUNCTION
Description - The primary functions of the Natural Testosterone Formula are to support the production of testosterone in
both men and women, and to support how tissues throughout the body respond to testosterone. This is accomplished by
supporting the function of testosterone producing glands in both genders, and by supporting the function of testosterone
tissues through the use of herbs that mimic the actions of testosterone.
NATURAL TESTOSTERONE FORMULA Suggested Usage: As a dietary supplement, adults may take 2 capsules
each day with food for 1 to 2 weeks or as directed by your healthcare professional. The dose may then be increased to
4 capsules each day with food for 2 to 4 months or as directed by your healthcare professional. After 2 to 4 months,
dosage may be lowered back down to 2 capsules each day with food and may continue on that dosage as needed or as
directed by your healthcare professional.
THE PRODUCT CONTAINS NO YEAST, WHEAT, GLUTEN, SOY PROTEIN, MILK/DAIRY, CORN, SO-
DIUM, SUGAR, STARCH, ARTIFICIAL COLORING, PRESERVATIVES OR FLAVORING.
9. Natural Testosterone Formula | Call 480.454.2370 to order! 9
Can men on testosterone replacement therapy
take NTF?
PROTECT THE PROSTATE
• Panax Ginseng decrease risks of prostate disorders in men receiving testosterone replacement therapy.
• Lepidium meyenii (Maca) prevented the prostate weight increase induced by testosterone enanthate treatment,
suggesting that Maca may decrease risks of prostate disorders in men receiving testosterone replacement therapy.
PROTECT THE BONES
• Eurycoma longifolia was suggested by researchers to be used with low-dose testosterone to treat male osteoporosis
without causing the side effects associated with full-dose testosterone replacement therapy.
Can men on testosterone replacement therapy
take NTF?
MAINTAIN TESTES FUNCTION A common side effect to testosterone re& therapy in men is decreased testosterone
function and decreased sperm count and decreased function due to the suppression of gonadotrophic) hormones, LH
& FSH. The gonadotrophic hormones would normally become elevated if testosterone was low, but become suppressed
with testosterone replacement therapy. That is why decreased gonad size and infertility is common in men who use
testosterone.
• Mucuna pruriens improves semen quality and sperm concentrations, sperms in infertile men.
• Tribulus terrestris has a significant effect on the sperm count due to its gonadotrophic-like activity.
• Eurycoma longifolia use can result in higher sperm count and improved sperm motility.
• Withania somnifera has gonadotrophic and
spermatogenic activity.
• Lepidium meyenii increases spermatogenesis in
males.
Cenegenics Natural
Testosterone Formula
AVAILABLE ON CENEGENICSSTORE.COM
RETAIL PRICE: $65.00
WHO CAN TAKE NATURAL TESTOSTERONE
FORMULA?
• Non-Cenegenics Patients & Cenegenics Patients
• Both Men & Women
• Individuals over the age of 18
WHO CANNOT TAKE NATURAL
TESTOSTERONE FORMULA?
• Women who are nursing or pregnant
• Individuals under the age of 18
10. Natural Testosterone Formula | Call 480.454.2370 to order!
10
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• Mehta AK, Binkley P, Gandhi SS, Ticku MK. Pharmacological effects of Withania somnifera root extract on GABAA receptor complex. Indian J Med Res. 1991
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• Muruganandam AV, Kumar V, Bhattacharya SK. Effect of poly herbal formulation, EuMil, on chronic stress-induced homeostatic perturbations in rats. Indian
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Review.
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