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OSCE
CF
OSCE 1- CASE SCENARIO
A 4-year-old boy has chronic nasal congestion,
poor weight gain, and frequent otitis media.
There has been no improvement with oral
antihistamines, topical decongestants, or topical
corticosteroid sprays. Physical examination of
the nares reveals bilateral polyps.
Presentation title 2
1-What is the most appropriate next study?
2-Enumerate 5 diseases associated with nasal polyposis?
3-What is your therapy?
Areas of focus
Presentation title 3
1- The boy described has nasal polyps associated with poor
weight gain, chronic otitis media, and nasal congestion. Any
child who presents with nasal polyps should be evaluated for
cystic fibrosis (CF) with a sweat chloride test.
2-Allergic fungal sinusitis, allergic rhinitis, aspirin sensitivity
(Samter triad ), chronic sinusitis, Kartagener syndrome, non-
allergic rhinitis, and Churg-Strauss syndrome.
3- Therapy for nasal polyps includes an initial investigation for
the underlying cause. Medical and surgical interventions have
included topical and systemic glucocorticoids, functional
endoscopic sinus surgery, and aspirin desensitization.
OSCE 2- COUNSELLING
You are a pediatrician providing genetic counseling to the
parents of a newborn baby who has been diagnosed with
cystic fibrosis through newborn screening. The parents
are understandably anxious and have many questions
about the implications of the diagnosis for their child's
health and their family's future.
Presentation title 4
Presentation title 5
• Introduction
• Begin by explaining what cystic fibrosis is and how it affects the body's systems, particularly the respiratory and
digestive systems.
• Emphasize that cystic fibrosis is a genetic condition caused by mutations in the CFTR gene, resulting in the production
of thick, sticky mucus that can clog the airways and lead to respiratory problems, as well as affect digestion and
nutrient absorption.
• Discuss the autosomal recessive inheritance pattern of cystic fibrosis, where both parents must be carriers of the
defective CFTR gene for the child to inherit the condition.
• Explain that each future pregnancy carries a 25% chance of having a child with cystic fibrosis if both parents are
carriers.
• Offer genetic testing for the parents to determine if they are carriers of the CFTR gene mutation.
• Explain the implications of carrier status for future pregnancies and the possibility of prenatal testing for cystic fibrosis
if desired.
• Outline the comprehensive treatment approach for cystic fibrosis, including medications to improve lung function,
nutritional support, airway clearance techniques, and regular medical monitoring.
• Discuss the importance of early intervention and adherence to treatment regimens to optimize health outcomes and
quality of life for the child.
• Provide information about local cystic fibrosis care centers, support groups, and resources available to help the family
navigate their journey with cystic fibrosis.
• Offer emotional support and reassurance to the parents, acknowledging the challenges they may face and
emphasizing that they are not alone in this journey.
• Schedule regular follow-up appointments to monitor the child's growth, development, and response to treatment.
• Queries
OSCE 3-
What sweat chloride concentration range is typically considered
indicative of cystic fibrosis?
A) < 10 mmol/L
B) 20-40 mmol/L
C) 30-60 mmol/L
D) > 80 mmol/L
Presentation title 6
OSCE 3-
What sweat chloride concentration range is typically considered
indicative of cystic fibrosis?
A) < 10 mmol/L
B) 20-40 mmol/L
C) 30-60 mmol/L
D) > 80 mmol/L
Presentation title 7
OSCE 4
Presentation title 8
OSCE 4
Presentation title 9
OSCE 4
Presentation title 10
Presentation title 11
Areas of focus
Presentation title 12
• Introduction
• Explain about the chronic nature of the disease
• Make it clear that its not their fault( as it’s a genetic problem)
• Common signs and Sx ( epistaxis, bleeding from gums, headache ,
vomiting, joint, muscle swelling)
• Offer genetic counselling and prenatal testing for the next pregnancy
• Discuss about factor prophylaxis
• Precautions during vaccination/ injection
• Avoid contact sports
• Ask if any queries
Agenda
Introduction
Primary goals
Areas of growth
Timeline
Summary
Presentation title 13
Introduction
At Contoso, we empower organizations to foster collaborative
thinking to further drive workplace innovation. By closing the
loop and leveraging agile frameworks, we help business grow
organically and foster a consumer-first mindset.
Presentation title 14
Primary goals
Annual revenue growth
Quarterly performance
4.5
3.5
2.5
4.3
2.8
1.8
4.4
2.4
5.0
3.0
2.0 2.0
-
1.0
2.0
3.0
4.0
5.0
6.0
Q4 Q3 Q2 Q1
Series 3 Series 2 Series 1
Presentation title 16
Areas of growth
B2B Supply chain ROI E-commerce
Q1 4.5 2.3 1.7 5.0
Q2 3.2 5.1 4.4 3.0
Q3 2.1 1.7 2.5 2.8
Q4 4.5 2.2 1.7 7.0
Presentation title 17
Business opportunities are like
buses. There's always another
one coming.
“ Richard Branson
”
Meet our team
Takuma Hayashi​
President
Mirjam Nilsson​
Chief Executive Officer
Flora Berggren​
Chief Operations Officer
Rajesh Santoshi​
VP Marketing
Presentation title 19
Meet our extended team
Takuma Hayashi​
President
Graham Barnes
VP Product
Mirjam Nilsson​
Chief Executive Officer
Rowan Murphy
SEO Strategist
Flora Berggren​
Chief Operations Officer
Elizabeth Moore
Product Designer
Rajesh Santoshi​
VP Marketing
Robin Kline
Content Developer
Presentation title 20
Plan for product launch
Presentation title 21
Planning
Synergize scalable
e-commerce
Marketing
Disseminate
standardized
metrics
Design
Coordinate e-
business
applications
Strategy
Foster holistically
superior
methodologies
Launch
Deploy strategic
networks with
compelling e-
business needs
Timeline
Presentation title 22
Synergize scalable e-
commerce
Sep 20XX
Disseminate standardized
metrics
Nov 20XX
Coordinate e-business
applications
Jan 20XX
Foster holistically superior
methodologies
Mar 20XX
Deploy strategic networks with
compelling e-business needs
May 20XX
How we get there
ROI
• Envision multimedia-based
expertise and cross-media
growth strategies
• Visualize quality intellectual
capital
• Engage worldwide
methodologies with web-
enabled technologies
Niche markets
• Pursue scalable customer
service through sustainable
strategies
• Engage top-line web services
with cutting-edge deliverables
Supply chains
• Cultivate one-to-one customer
service with robust ideas
• Maximize timely deliverables
for real-time schemas
Presentation title 23
Thank you
Mirjam Nilsson​
mirjam@contoso.co
m
www.contoso.com

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CCYSTIC FIBROSIS DISEASE QUESTIONS OSCE.pptx

  • 2. OSCE 1- CASE SCENARIO A 4-year-old boy has chronic nasal congestion, poor weight gain, and frequent otitis media. There has been no improvement with oral antihistamines, topical decongestants, or topical corticosteroid sprays. Physical examination of the nares reveals bilateral polyps. Presentation title 2 1-What is the most appropriate next study? 2-Enumerate 5 diseases associated with nasal polyposis? 3-What is your therapy?
  • 3. Areas of focus Presentation title 3 1- The boy described has nasal polyps associated with poor weight gain, chronic otitis media, and nasal congestion. Any child who presents with nasal polyps should be evaluated for cystic fibrosis (CF) with a sweat chloride test. 2-Allergic fungal sinusitis, allergic rhinitis, aspirin sensitivity (Samter triad ), chronic sinusitis, Kartagener syndrome, non- allergic rhinitis, and Churg-Strauss syndrome. 3- Therapy for nasal polyps includes an initial investigation for the underlying cause. Medical and surgical interventions have included topical and systemic glucocorticoids, functional endoscopic sinus surgery, and aspirin desensitization.
  • 4. OSCE 2- COUNSELLING You are a pediatrician providing genetic counseling to the parents of a newborn baby who has been diagnosed with cystic fibrosis through newborn screening. The parents are understandably anxious and have many questions about the implications of the diagnosis for their child's health and their family's future. Presentation title 4
  • 5. Presentation title 5 • Introduction • Begin by explaining what cystic fibrosis is and how it affects the body's systems, particularly the respiratory and digestive systems. • Emphasize that cystic fibrosis is a genetic condition caused by mutations in the CFTR gene, resulting in the production of thick, sticky mucus that can clog the airways and lead to respiratory problems, as well as affect digestion and nutrient absorption. • Discuss the autosomal recessive inheritance pattern of cystic fibrosis, where both parents must be carriers of the defective CFTR gene for the child to inherit the condition. • Explain that each future pregnancy carries a 25% chance of having a child with cystic fibrosis if both parents are carriers. • Offer genetic testing for the parents to determine if they are carriers of the CFTR gene mutation. • Explain the implications of carrier status for future pregnancies and the possibility of prenatal testing for cystic fibrosis if desired. • Outline the comprehensive treatment approach for cystic fibrosis, including medications to improve lung function, nutritional support, airway clearance techniques, and regular medical monitoring. • Discuss the importance of early intervention and adherence to treatment regimens to optimize health outcomes and quality of life for the child. • Provide information about local cystic fibrosis care centers, support groups, and resources available to help the family navigate their journey with cystic fibrosis. • Offer emotional support and reassurance to the parents, acknowledging the challenges they may face and emphasizing that they are not alone in this journey. • Schedule regular follow-up appointments to monitor the child's growth, development, and response to treatment. • Queries
  • 6. OSCE 3- What sweat chloride concentration range is typically considered indicative of cystic fibrosis? A) < 10 mmol/L B) 20-40 mmol/L C) 30-60 mmol/L D) > 80 mmol/L Presentation title 6
  • 7. OSCE 3- What sweat chloride concentration range is typically considered indicative of cystic fibrosis? A) < 10 mmol/L B) 20-40 mmol/L C) 30-60 mmol/L D) > 80 mmol/L Presentation title 7
  • 12. Areas of focus Presentation title 12 • Introduction • Explain about the chronic nature of the disease • Make it clear that its not their fault( as it’s a genetic problem) • Common signs and Sx ( epistaxis, bleeding from gums, headache , vomiting, joint, muscle swelling) • Offer genetic counselling and prenatal testing for the next pregnancy • Discuss about factor prophylaxis • Precautions during vaccination/ injection • Avoid contact sports • Ask if any queries
  • 13. Agenda Introduction Primary goals Areas of growth Timeline Summary Presentation title 13
  • 14. Introduction At Contoso, we empower organizations to foster collaborative thinking to further drive workplace innovation. By closing the loop and leveraging agile frameworks, we help business grow organically and foster a consumer-first mindset. Presentation title 14
  • 17. Areas of growth B2B Supply chain ROI E-commerce Q1 4.5 2.3 1.7 5.0 Q2 3.2 5.1 4.4 3.0 Q3 2.1 1.7 2.5 2.8 Q4 4.5 2.2 1.7 7.0 Presentation title 17
  • 18. Business opportunities are like buses. There's always another one coming. “ Richard Branson ”
  • 19. Meet our team Takuma Hayashi​ President Mirjam Nilsson​ Chief Executive Officer Flora Berggren​ Chief Operations Officer Rajesh Santoshi​ VP Marketing Presentation title 19
  • 20. Meet our extended team Takuma Hayashi​ President Graham Barnes VP Product Mirjam Nilsson​ Chief Executive Officer Rowan Murphy SEO Strategist Flora Berggren​ Chief Operations Officer Elizabeth Moore Product Designer Rajesh Santoshi​ VP Marketing Robin Kline Content Developer Presentation title 20
  • 21. Plan for product launch Presentation title 21 Planning Synergize scalable e-commerce Marketing Disseminate standardized metrics Design Coordinate e- business applications Strategy Foster holistically superior methodologies Launch Deploy strategic networks with compelling e- business needs
  • 22. Timeline Presentation title 22 Synergize scalable e- commerce Sep 20XX Disseminate standardized metrics Nov 20XX Coordinate e-business applications Jan 20XX Foster holistically superior methodologies Mar 20XX Deploy strategic networks with compelling e-business needs May 20XX
  • 23. How we get there ROI • Envision multimedia-based expertise and cross-media growth strategies • Visualize quality intellectual capital • Engage worldwide methodologies with web- enabled technologies Niche markets • Pursue scalable customer service through sustainable strategies • Engage top-line web services with cutting-edge deliverables Supply chains • Cultivate one-to-one customer service with robust ideas • Maximize timely deliverables for real-time schemas Presentation title 23