CBCC Group was founded in 1984 in the US as a small cancer clinic and has since expanded significantly both in the US and India. It now operates the largest cancer center on the west coast of the US as well as multiple sites across India. CBCC provides biorepository services including collection, processing, and long-term storage of biospecimens from oncology and other clinical trials. It has processed over 80,000 specimens from the US and over 4,000 from India. CBCC aims to support research through high quality, compliant collection and storage of a variety of sample types across many disease areas.

1. USA ● INDIA
1

2. CBCC Group - Journey at a glance
1984 Founded by Dr. Ravi Patel with small cancer clinic of 12,000 Sq. ft.
1990 Expanded into a larger facility with several stations
Began to participate in oncology clinical trials with affiliation to UCLA.1995
1996 Renamed clinic to Comprehensive Blood & Cancer Centre (CBCC).
2007  Opened a new 70,000 sq ft cancer centre becoming the largest centre on west coast, USA.
2008 Inaugurated a brand new centre CBCC CyberKnife® Center.
2011  Acquired an HDXT MRI for expanding diagnosis for Breast Cancer.
2015
 Started operation in Gujarat, India.
 Started operation in other Indian states Chaatisgadh, Madhya Pradesh and Andhra Pradesh.
Started operation in Tamilnadu, India.
2012 Acquired Vibgyor Research India to manage India Operation.
www.cbcc.com
2

3. www.cbcc.com
3
• Purpose-built, state of the art Bio repository facility for receipt, processing,
storage and archival of human bio specimens in India and the US
• Seven (7) Oncology sites managed by CBCC in India in addition to a network of
> 80 sites across India
• Our experienced team trains the Investigators and site staff to ensure high
quality specimen collection & handling
• Compliance with Ethics committee approved protocol and National &
International guidelines (ICMR, ISBER, NCI, HIPAA)
• Processed over 80,000 specimens for Oncology in the US till date
• Processed over 4,000 specimens across multiple sites for Oncology in India in a
span of over a year
• Robust systems in place to ensure Quality compliance at all levels
About CBCC’s Biorepository

4. 4
Infrastructure at our Biorepository
Short to long-term
specimen storage
• State-of-the-art banking
facility
• Custom designed LIMS
complying with all
regulatory requirements
• Qualified, Trained and
experienced staff led by
a Pathologist
Safety & Security
• Storage equipments with
monitoring system to
monitor temperature and
humidity - 24/7
• Emergency back-up
(72hrs) generators for total
support coupled with 24/7
emergency response
services
• 24-hour restricted access
facility with security
surveillance
• Secured data access to
authorized personnel via
log in and password
protection.
Flexibility & Scalability
• Range of frozen storage
conditions including
ambient, 2 to 8°C, -20°C,
-40°C, -80°C, and -190°C
vapor phase liquid
nitrogen & dipin LN2
(-196°C)
• Adaptable storage options
e.g. freezer assignment for
larger containers /
dedicated single shelf to
cater to individual
requests
• Capacity to store broad
sample types including
plasma, serum, whole
blood, DNA, PBMC and
tissue

5. Specimens we can source
5
www.cbcc.com
•Tissue samples with well preserved RNA and proteins
•Samples from a wide variety of organs, diseases, cancers and
adjacent normal tissue
•Tissue samples available with matched serum
Human Tissue
•FFPE samples from various diseased and adjacent normal tissues
Human, Formalin-Fixed,
Paraffin-Embedded
Tissue (FFPE)
•Samples from several disease types and disease-free normal
controls
•Collected by validated protocols
Human Serum
•Fresh, whole Blood & Peripheral Blood Mononuclear Cells (PBMCs)
•Plasma & Serum
•Buffy Coat & Circulating Tumor Cells (CTCs)
Blood Products
•Saliva, Cerebrospinal and other fluids
•Urine, Nail clippings & hair
•Semen & cervical swabs
Others

6. Therapeutic areas
6
www.cbcc.com
•Breast Cancer, Lung Cancer, Thyroid cancer
•Head and neck cancers
•Prostate cancer, Gynecological Cancer, Colorectal Cancer
Oncology
•Acute and Chronic Myeloid Leukemia; Acute and Chronic
Lymphocytic Leukemia
•Multiple Myeloma Thalassemia
•Myelodysplastic Syndrome
Hematology
•Rheumatoid Arthritis
•Systemic Lupus ErythematosusImmunology
•Type I & II Diabetes
•Cirrhosis of liver
Metabolic
diseases

7. www.cbcc.com
7
Our sample collection process
Protocol
development
Training of
Investigators/site
staff/BR monitor on
protocol
IEC approval and
Patient consent
Specimen
collection & labeling
using project
specific collection
kits
Review & monitor
patient consent and
data collection
procedures
Storage at sites,
packaging and
shipping to CBCC
Biorepository under
controlled
conditions
Customized case report forms as per the collection protocol to capture the exact type of
data needed e.g. clinical, molecular, demographic, lifestyle, family history etc.

8. 8
Why select us for your Biorepository
requirements?
Project
Management
Project delivery on-time
to accelerate your
research programs
Project visibility – Open
& Honest
communication
Comprehensive project
management plans &
updates at each stage
High Quality
100% consent and
100% monitoring
Collection according to
uniform validated
protocols across all sites
All our operations abide
by the ISBER
Annotated
samples
Detailed demographic
information, including
family history
Clinical diagnostic
information
Complete medication
history & full pathology
report

9. 9
Why select us for your Biorepository
requirements?
Logistics
Logistics partners
capable of shipment
compliance
management
Real time shipment
tracking
Temperature
monitoring
Customized
sample
sourcing
Site selection as per
specimen requirements
Feasibility assessments
to estimate accurate
timelines
Project specific
collection kits
Ethical
consideration
Adherence to all
applicable ethical, legal
& regulatory guidelines
IEC approved protocols
for sample collection
Sample identification
only by Unique codes to
protect patient privacy

10. www.cbcc.com
10
THANK YOU