This document reviews the differences in fatty acid profiles and antioxidant content between grass-fed and grain-fed beef. It finds that grass-fed beef has higher levels of beneficial fatty acids like conjugated linoleic acid and omega-3 fatty acids. Grass-fed beef also contains more antioxidants like vitamin E, glutathione, and superoxide dismutase. However, grass-fed beef may have a stronger grassy flavor and different cooking properties than grain-fed beef. The document concludes that grass-fed beef has a healthier fatty acid composition but also notes differences in taste that consumers should be aware of.
In this slide deck I demonstrate the effects of carbohydrate restriction on different lipoproteins such as HDL, LDL, non-HDL-cholesterol and apolipoprotein B (apoB). The effect of butter and saturated fat as such are compared to unsaturated fat and especially to canola oil. Meta-analysis by Mensink et al. 2003 is the primary reference for the analysis.
The recovery and re-evaluation of the old data on Sydney Diet Heart Study uncovers unexpected outcomes. However, interpret with care because things have changed since 1970s.
1. Diet lower in carbohydrates seems to lead to increased LDL particle size. However, the effect of diet on LDL particle size is controversial.
2. When carbohydrate intake is high and comparable between groups, the effects of fatty acids like saturated fat, monounsaturated fat, and polyunsaturated fat on LDL particle size are also controversial.
3. When on a low carbohydrate diet high in red meat, replacing saturated fat with monounsaturated fat increases LDL particle size.
This document summarizes a study assessing the potential socioeconomic impacts if meat protein extracts (MPE) were widely implemented in processed meat in the United States to reduce salt intake. MPE is a broth made from hydrolyzed meat protein that can reduce salt in processed meat by over 30% without compromising taste or texture. The study estimates the health and cost savings based on literature showing benefits from reduced salt intake, such as fewer hypertension cases and healthcare cost savings. It is estimated that if MPE reduced US salt intake by 5%, it could help avoid 1 million hypertension cases and save $1.6 billion annually in direct healthcare costs.
LACTOWHEY powder: Provides body’s defense against cancerSriramNagarajan18
Lactowhey powder is a whey protein supplement that provides several potential health benefits. It contains amino acids that help stimulate immunity and increase glutathione levels, which enhances the body's defense against cancer, free radicals, and carcinogens. Pre-clinical and clinical studies have shown that Lactowhey powder may help prevent muscle loss and weight loss in cancer patients by improving nutritional status and appetite. The whey proteins and other components in Lactowhey powder are easily absorbed and can promote muscle strength and immune function.
In this slide deck, I describe the up-to-date evidence on Low Carbs and heart health. The evidence is based mainly on two recent meta-analyses (Hession et al. & Kodama et al.) and prospective cohort studies. Limited evidence on renal aspects is also demonstrated.
This document discusses glycine, an amino acid that has anti-inflammatory properties and may be conditionally essential for humans. It covers glycine's role in collagen production, metabolic syndrome, stroke, and other diseases. Studies show glycine supplementation can reduce inflammation and improve metabolic markers in people with conditions like metabolic syndrome and diabetes. Animal studies also indicate glycine's protective effects against liver damage, cancer, and other issues. Dietary sources of glycine include collagen, gelatin, bone broth, and magnesium glycinate.
Fat intake US has remained rather stable during the past decades despite many claims. I present here the case based on USDA and NHANES data.
Claiming that fat intake has decreased in US is as silly as advising a dieter: “If you want to follow a low-fat diet just keep your fat intake at the current level and simply increase the consumption of carbs. Then you are on low-fat diet and you will reap all the benefits of the diet”
In this slide deck I demonstrate the effects of carbohydrate restriction on different lipoproteins such as HDL, LDL, non-HDL-cholesterol and apolipoprotein B (apoB). The effect of butter and saturated fat as such are compared to unsaturated fat and especially to canola oil. Meta-analysis by Mensink et al. 2003 is the primary reference for the analysis.
The recovery and re-evaluation of the old data on Sydney Diet Heart Study uncovers unexpected outcomes. However, interpret with care because things have changed since 1970s.
1. Diet lower in carbohydrates seems to lead to increased LDL particle size. However, the effect of diet on LDL particle size is controversial.
2. When carbohydrate intake is high and comparable between groups, the effects of fatty acids like saturated fat, monounsaturated fat, and polyunsaturated fat on LDL particle size are also controversial.
3. When on a low carbohydrate diet high in red meat, replacing saturated fat with monounsaturated fat increases LDL particle size.
This document summarizes a study assessing the potential socioeconomic impacts if meat protein extracts (MPE) were widely implemented in processed meat in the United States to reduce salt intake. MPE is a broth made from hydrolyzed meat protein that can reduce salt in processed meat by over 30% without compromising taste or texture. The study estimates the health and cost savings based on literature showing benefits from reduced salt intake, such as fewer hypertension cases and healthcare cost savings. It is estimated that if MPE reduced US salt intake by 5%, it could help avoid 1 million hypertension cases and save $1.6 billion annually in direct healthcare costs.
LACTOWHEY powder: Provides body’s defense against cancerSriramNagarajan18
Lactowhey powder is a whey protein supplement that provides several potential health benefits. It contains amino acids that help stimulate immunity and increase glutathione levels, which enhances the body's defense against cancer, free radicals, and carcinogens. Pre-clinical and clinical studies have shown that Lactowhey powder may help prevent muscle loss and weight loss in cancer patients by improving nutritional status and appetite. The whey proteins and other components in Lactowhey powder are easily absorbed and can promote muscle strength and immune function.
In this slide deck, I describe the up-to-date evidence on Low Carbs and heart health. The evidence is based mainly on two recent meta-analyses (Hession et al. & Kodama et al.) and prospective cohort studies. Limited evidence on renal aspects is also demonstrated.
This document discusses glycine, an amino acid that has anti-inflammatory properties and may be conditionally essential for humans. It covers glycine's role in collagen production, metabolic syndrome, stroke, and other diseases. Studies show glycine supplementation can reduce inflammation and improve metabolic markers in people with conditions like metabolic syndrome and diabetes. Animal studies also indicate glycine's protective effects against liver damage, cancer, and other issues. Dietary sources of glycine include collagen, gelatin, bone broth, and magnesium glycinate.
Fat intake US has remained rather stable during the past decades despite many claims. I present here the case based on USDA and NHANES data.
Claiming that fat intake has decreased in US is as silly as advising a dieter: “If you want to follow a low-fat diet just keep your fat intake at the current level and simply increase the consumption of carbs. Then you are on low-fat diet and you will reap all the benefits of the diet”
The document discusses factors that influence the bioavailability of omega-3 fatty acids from supplements. It finds that re-esterified triglyceride forms of omega-3s have higher bioavailability than ethyl-ester forms. The bioavailability of krill oil is similar to fish oil when doses are matched for EPA and DHA content. Higher doses of EPA and DHA from supplements are needed to raise omega-3 blood levels, with requirements varying based on starting levels, age, sex, weight, and activity levels.
A randomized controlled trial studied the effects of low-carbohydrate diets with either low or high saturated fat content on cardiovascular risk factors in 40 healthy men. The men were randomly assigned to follow either a low-carbohydrate diet with beef as the main protein source and low saturated fat or the same diet with high saturated fat for 3 weeks, separated by a 2-week washout period. Compared to the high saturated fat diet, the low saturated fat diet improved cardiovascular risk markers like LDL cholesterol, HDL cholesterol, and LDL particle size. Replacing carbohydrates with beef and high saturated fat as part of a low-carbohydrate diet did not provide benefits and may have deleterious health effects.
Vladimir Heiskanen - Glycine: The Versatile Anti-inflammatory Nutrient (1st v...Vladimir Heiskanen
This document provides an overview of glycine, an amino acid that can have anti-inflammatory effects. It discusses how glycine may be conditionally essential for humans. Studies show glycine can help prevent metabolic syndrome by reducing inflammation caused by sugar, fat, and alcohol intake. Glycine also appears to protect against stroke and shows benefits for diseases like diabetes, cancer, and liver damage in animal studies. High-dose glycine supplements have helped with conditions like schizophrenia in humans. Dietary sources of glycine include collagen supplements, bone broth, and meat.
Dr Q's Perfect Meal is a protein supplement powder containing a proprietary blend of New Zealand whey protein concentrate, glutamine, glycine, and taurine. It also contains fiber, medium-chain triglycerides, and other nutrients. The document discusses the various health benefits of the ingredients, such as supporting muscle recovery, immune function, gastrointestinal health, and body composition. It provides details on the product's macronutrient ratio and lack of fructose.
In a randomized trial comparing low-carbohydrate and low-fat diets in patients with type 2 diabetes, both diets produced similar weight loss over 2 years but glycemic control improved more with low-carbohydrate. Low-carbohydrate increased HDL cholesterol levels but had no other effects on lipids or blood pressure. While glycemic control benefits were transient, low-carbohydrate was not shown to have metabolic risks even with higher saturated fat intake.
Coconut oil was taken off the shelves for much of the 20th century due to concerns over its fat content. But by the turn of the century, coconut oil has exploded into one of the trendiest foods over the last 10-15 years. Learn the science behind the myths that coconut oil is bad for you.
Meat in Human Diet: Balance between nutrition and health
Limitations of prospective cohort studies and epidemiological studies and with respect to less meat affluent countries
IOSR Journal of Pharmacy (IOSRPHR), www.iosrphr.org, call for paper, research...iosrphr_editor
This document summarizes the effects of physical activity during Ramadan fasting on body composition, hematological, and biochemical parameters. Some key findings include:
1. Energy and macronutrient intake decreased for some athletes during Ramadan, while intake was unchanged for others, depending on dietary habits and food choices.
2. Water intake decreased for many athletes during Ramadan, increasing risk of dehydration.
3. Body mass and body fat percentage decreased for some athletes during Ramadan, while remaining unchanged for others, depending on dietary intake and training regimen.
The document summarizes nutritional aspects of bone health and fracture healing. It discusses how insufficient intake of certain vitamins and nutrients can negatively impact bone health and fracture healing time. Specifically, it covers how vitamins A and D, calcium, phosphorus, sodium, and other micronutrients like copper and zinc are important for bone health and influence fracture risk and healing. Maintaining adequate intake of both macro and micronutrients through diet is essential for bone health, decreasing fracture risk, and enhancing healing after fractures.
Hypertrophic obesity is associated with type 2 diabetes and impaired adipogen...My Healthy Waist
By Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden
This document discusses the health benefits and safety of omega-3 fatty acids found in fish oil. It covers the mechanisms by which omega-3s may help prevent atherosclerosis such as reducing inflammation and triglyceride levels. Potential side effects are mild and include belching or loose stools. While fish oil supplements are generally safe, high doses over long periods could potentially cause bleeding or toxicity from oxidation or excessive vitamins if not purified properly. Research shows fish oil may help reduce risk of heart disease by lowering triglycerides and inflammation.
Journal of Nutritional Health and Food Engineering-02-00046Patricia Funk
This article reviews the role of glutamine, arginine, and β-hydroxy-β-methylbutyrate (HMB) supplements in enhancing athletic performance and benefiting the body during times of stress, illness, and wound healing. It finds that glutamine, arginine, and HMB may help preserve lean body mass, decrease muscle breakdown, and support immune function and wound healing. However, the evidence for their effects on athletic performance is limited and contradictory. Larger, well-designed studies are still needed to define the potential benefits of these supplements for enhancing athletic performance and lean body mass.
2010 carbohydrate for weight and metabolic control- where do we standAgrin Life
This document reviews the evidence on carbohydrate intake for weight and metabolic control. It discusses how recommendations have generally advocated high carbohydrate intake but the prevalence of obesity and diabetes has still increased. Recent evidence suggests diets lower in carbohydrates and higher in unsaturated fats or protein may facilitate weight loss and improve health markers independent of weight loss. The document concludes that future studies are still needed to determine if diets with a more balanced macronutrient composition than currently recommended could better support weight and metabolic health.
Abdominal obesity, intra-abdominal adiposity and related cardiometabolic risk...My Healthy Waist
By Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada.
Medical experts should consider minimal and optimal levels of protein intake for their patients. This presentation discusses the current RDA & how this affects the nutritional balance of a person's well being.
Check out more information at http://www.GoBeneVia.com/blog
Park Termik A.Ş. operates the Çayırhan Thermal Power Plant in Turkey. An accident occurred where ash was blown over 225 square kilometers from one of the plant's units. This affected one town and nine villages with ash rains. Action was taken to analyze the situation, inform authorities, set up a crisis management team, and communicate through press releases and social media. Efforts were made to transport affected people and livestock to safety, clean the area, compensate losses, and eliminate environmental concerns. A symposium was later held to discuss the crisis management process in a transparent manner.
Essential for a great web experience e briks infotechebriksinfotech
Speed is essential for a good user experience on the web. Page load time impacts metrics like abandonment rates and conversion rates. The majority of page load time is spent downloading assets from the front-end like scripts, stylesheets, and images rather than backend processing. Techniques for improving performance include compressing assets, reducing requests, leveraging the browser cache, optimizing images for different devices, loading scripts asynchronously, and addressing third-party script blocking. Performance must be considered across many factors like network conditions, device capabilities, and business goals.
Amster 2003 - patterns of exclusion sanitizing space, criminaliAlma Nuñez
This document discusses how homeless individuals are often portrayed in a negative light and subjected to practices that exclude them from public spaces. It explores how homelessness has historically been associated with images of dirt, disease, criminality, and moral failings. These perceptions have led to policies and actions that aim to sanitize public areas by restricting or removing homeless people. The document argues these practices reflect societal fears and desires to control spaces rather than actual threats posed by homeless individuals. It examines how portrayals of homelessness in academic and media sources sometimes unintentionally contribute to stereotypes of the homeless as dirty and diseased.
The document discusses factors that influence the bioavailability of omega-3 fatty acids from supplements. It finds that re-esterified triglyceride forms of omega-3s have higher bioavailability than ethyl-ester forms. The bioavailability of krill oil is similar to fish oil when doses are matched for EPA and DHA content. Higher doses of EPA and DHA from supplements are needed to raise omega-3 blood levels, with requirements varying based on starting levels, age, sex, weight, and activity levels.
A randomized controlled trial studied the effects of low-carbohydrate diets with either low or high saturated fat content on cardiovascular risk factors in 40 healthy men. The men were randomly assigned to follow either a low-carbohydrate diet with beef as the main protein source and low saturated fat or the same diet with high saturated fat for 3 weeks, separated by a 2-week washout period. Compared to the high saturated fat diet, the low saturated fat diet improved cardiovascular risk markers like LDL cholesterol, HDL cholesterol, and LDL particle size. Replacing carbohydrates with beef and high saturated fat as part of a low-carbohydrate diet did not provide benefits and may have deleterious health effects.
Vladimir Heiskanen - Glycine: The Versatile Anti-inflammatory Nutrient (1st v...Vladimir Heiskanen
This document provides an overview of glycine, an amino acid that can have anti-inflammatory effects. It discusses how glycine may be conditionally essential for humans. Studies show glycine can help prevent metabolic syndrome by reducing inflammation caused by sugar, fat, and alcohol intake. Glycine also appears to protect against stroke and shows benefits for diseases like diabetes, cancer, and liver damage in animal studies. High-dose glycine supplements have helped with conditions like schizophrenia in humans. Dietary sources of glycine include collagen supplements, bone broth, and meat.
Dr Q's Perfect Meal is a protein supplement powder containing a proprietary blend of New Zealand whey protein concentrate, glutamine, glycine, and taurine. It also contains fiber, medium-chain triglycerides, and other nutrients. The document discusses the various health benefits of the ingredients, such as supporting muscle recovery, immune function, gastrointestinal health, and body composition. It provides details on the product's macronutrient ratio and lack of fructose.
In a randomized trial comparing low-carbohydrate and low-fat diets in patients with type 2 diabetes, both diets produced similar weight loss over 2 years but glycemic control improved more with low-carbohydrate. Low-carbohydrate increased HDL cholesterol levels but had no other effects on lipids or blood pressure. While glycemic control benefits were transient, low-carbohydrate was not shown to have metabolic risks even with higher saturated fat intake.
Coconut oil was taken off the shelves for much of the 20th century due to concerns over its fat content. But by the turn of the century, coconut oil has exploded into one of the trendiest foods over the last 10-15 years. Learn the science behind the myths that coconut oil is bad for you.
Meat in Human Diet: Balance between nutrition and health
Limitations of prospective cohort studies and epidemiological studies and with respect to less meat affluent countries
IOSR Journal of Pharmacy (IOSRPHR), www.iosrphr.org, call for paper, research...iosrphr_editor
This document summarizes the effects of physical activity during Ramadan fasting on body composition, hematological, and biochemical parameters. Some key findings include:
1. Energy and macronutrient intake decreased for some athletes during Ramadan, while intake was unchanged for others, depending on dietary habits and food choices.
2. Water intake decreased for many athletes during Ramadan, increasing risk of dehydration.
3. Body mass and body fat percentage decreased for some athletes during Ramadan, while remaining unchanged for others, depending on dietary intake and training regimen.
The document summarizes nutritional aspects of bone health and fracture healing. It discusses how insufficient intake of certain vitamins and nutrients can negatively impact bone health and fracture healing time. Specifically, it covers how vitamins A and D, calcium, phosphorus, sodium, and other micronutrients like copper and zinc are important for bone health and influence fracture risk and healing. Maintaining adequate intake of both macro and micronutrients through diet is essential for bone health, decreasing fracture risk, and enhancing healing after fractures.
Hypertrophic obesity is associated with type 2 diabetes and impaired adipogen...My Healthy Waist
By Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden
This document discusses the health benefits and safety of omega-3 fatty acids found in fish oil. It covers the mechanisms by which omega-3s may help prevent atherosclerosis such as reducing inflammation and triglyceride levels. Potential side effects are mild and include belching or loose stools. While fish oil supplements are generally safe, high doses over long periods could potentially cause bleeding or toxicity from oxidation or excessive vitamins if not purified properly. Research shows fish oil may help reduce risk of heart disease by lowering triglycerides and inflammation.
Journal of Nutritional Health and Food Engineering-02-00046Patricia Funk
This article reviews the role of glutamine, arginine, and β-hydroxy-β-methylbutyrate (HMB) supplements in enhancing athletic performance and benefiting the body during times of stress, illness, and wound healing. It finds that glutamine, arginine, and HMB may help preserve lean body mass, decrease muscle breakdown, and support immune function and wound healing. However, the evidence for their effects on athletic performance is limited and contradictory. Larger, well-designed studies are still needed to define the potential benefits of these supplements for enhancing athletic performance and lean body mass.
2010 carbohydrate for weight and metabolic control- where do we standAgrin Life
This document reviews the evidence on carbohydrate intake for weight and metabolic control. It discusses how recommendations have generally advocated high carbohydrate intake but the prevalence of obesity and diabetes has still increased. Recent evidence suggests diets lower in carbohydrates and higher in unsaturated fats or protein may facilitate weight loss and improve health markers independent of weight loss. The document concludes that future studies are still needed to determine if diets with a more balanced macronutrient composition than currently recommended could better support weight and metabolic health.
Abdominal obesity, intra-abdominal adiposity and related cardiometabolic risk...My Healthy Waist
By Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada.
Medical experts should consider minimal and optimal levels of protein intake for their patients. This presentation discusses the current RDA & how this affects the nutritional balance of a person's well being.
Check out more information at http://www.GoBeneVia.com/blog
Park Termik A.Ş. operates the Çayırhan Thermal Power Plant in Turkey. An accident occurred where ash was blown over 225 square kilometers from one of the plant's units. This affected one town and nine villages with ash rains. Action was taken to analyze the situation, inform authorities, set up a crisis management team, and communicate through press releases and social media. Efforts were made to transport affected people and livestock to safety, clean the area, compensate losses, and eliminate environmental concerns. A symposium was later held to discuss the crisis management process in a transparent manner.
Essential for a great web experience e briks infotechebriksinfotech
Speed is essential for a good user experience on the web. Page load time impacts metrics like abandonment rates and conversion rates. The majority of page load time is spent downloading assets from the front-end like scripts, stylesheets, and images rather than backend processing. Techniques for improving performance include compressing assets, reducing requests, leveraging the browser cache, optimizing images for different devices, loading scripts asynchronously, and addressing third-party script blocking. Performance must be considered across many factors like network conditions, device capabilities, and business goals.
Amster 2003 - patterns of exclusion sanitizing space, criminaliAlma Nuñez
This document discusses how homeless individuals are often portrayed in a negative light and subjected to practices that exclude them from public spaces. It explores how homelessness has historically been associated with images of dirt, disease, criminality, and moral failings. These perceptions have led to policies and actions that aim to sanitize public areas by restricting or removing homeless people. The document argues these practices reflect societal fears and desires to control spaces rather than actual threats posed by homeless individuals. It examines how portrayals of homelessness in academic and media sources sometimes unintentionally contribute to stereotypes of the homeless as dirty and diseased.
This document provides information about a 2011 field trip to Seoraksan National Park led by Professor Chang Zin Lee from Chungbuk National University. It includes schedules, maps, and descriptions of the geology that participants will investigate over a 3 day period in late September and early October. The itinerary involves hiking between different sites to observe granites, gneisses, and other rock types along with their structures and weathering features. Participants will learn about the geological history and formation of the park, which contains rare species and was designated as a biosphere preservation district. The document seeks to educate about the rocks, landforms, and natural history of Seoraksan National Park through this guided field experience.
This document discusses the relationship between nutrition and cardiovascular disease. It covers macronutrients like carbohydrates, proteins, fats and micronutrients like vitamins and minerals. Specific topics covered include dietary fiber, glycemic index and load, saturated and unsaturated fats including monounsaturated, polyunsaturated omega-3 and trans fats. Studies are cited showing relationships between various nutrients and cardiovascular risk factors and disease outcomes. Guidelines from cardiovascular organizations on nutritional recommendations are also mentioned.
nutrition dietary fiber fat community medicineAISWARYA A S
This document discusses fats and dietary fiber. It covers several topics:
1) Fats can encourage obesity if consumed in excess and are linked to conditions like phrynoderma and coronary heart disease. High fat diets may also increase cancer risk.
2) Dietary fiber provides health benefits like reduced risk of heart disease and regulated blood sugar. It is fermented in the intestines and produces acids that support gut health.
3) Sources of fiber include fruits, vegetables, whole grains, and legumes. The recommended daily intake is 30 grams, though too much fiber can decrease nutrient absorption.
Fatty Acids and their role in Cardiometabolic HealthArindam Pande
This document discusses fatty acids and their role in cardiometabolic health. It summarizes that the conventional view of the diet-heart hypothesis, which links saturated fat and cholesterol to heart disease, may be an oversimplification. Different fatty acids, including saturated fatty acids found in dairy, can have varying metabolic effects. Replacing saturated fats with polyunsaturated fats may lower heart disease risk, but replacing them with carbohydrates does not. Ongoing research is exploring the cardiovascular impacts of omega-3 supplements and specific plant oils. In conclusion, the type of fat consumed is important for heart health, not just total fat intake, and dietary patterns rather than single nutrients should be the focus.
Nutraceutical and functional food:as a remedy for chronical diseasesAayush Wadhwa
A thorough presentation for reference only. I have discussed detailed mechanisms and processes of various food components in diet and how they are associated with chronical diseses
Development and Standardisation of Nutri Bar using Oats, Wheat Bran and Flax ...ijtsrd
Cardiovascular diseases continue to be the major cause of morbidity and mortality in industrialized society. Various studies indicate the consumption of a vegetarian diet or a diet high in cereal fiber appears to be associated with reduced risk of cardiovascular diseases. Based on this, a product was developed which is not only high in fiber, low in saturated fats, high in PUFA and MUFA but also a good source of phytochemicals and antioxidant. The products were developed basic with sugar sample A, variations with jaggery sample B and artificial sweetener sample C using bajra, oats, wheat bran, flax seeds, whole green gram, almonds and walnuts. The nutritive value per 100g of the basic recipe energy – 389kcal, protein 13g, fat – 12g, fiber – 6.5g and variations were calculated. The pH and alcoholic acidity of the products were estimated using standard procedures. The products were subjected to sensory analysis through Hedonic rating test and the results revealed that sample B scored the highest. The cost of the products per 100g ranged from Rs. 9 to Rs. 14. From the results it is clear that the sample B prepared with jaggery was the most acceptable and hence, can be recommended for the patients suffering with cardiovascular diseases. Rumana Farooqui | P. Ashlesha | Shruti Kabra "Development and Standardisation of Nutri Bar using Oats, Wheat Bran and Flax Seeds" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-2 , February 2021, URL: https://www.ijtsrd.com/papers/ijtsrd38342.pdf Paper Url: https://www.ijtsrd.com/home-science/food-and-nutrition/38342/development-and-standardisation-of-nutri-bar-using-oats-wheat-bran-and-flax-seeds/rumana-farooqui
Consumption of saturated animal fats in the diet of humans may decrease the r...banafsheh61
This document summarizes research on the relationship between saturated fat consumption and heart disease risk. It discusses several studies that found no correlation or an inverse correlation between saturated fat intake and heart disease rates. It also profiles the diets of various tribes and populations that consume high amounts of saturated fat from animals but have low rates of heart disease. The document concludes that based on studies of healthy populations and biological needs, consuming saturated fats from animals may not increase and could potentially decrease risk of heart disease.
Consumption of saturated animal fats in the diet of humans may decrease the r...banafsheh61
Fats, as part of the human dietary regime are a concentrated source of energy. Animals contain saturated and plants contain unsaturated type of fatty acids. In this prospective research, the role of animal saturated fatty acids is highlighted and is proven to be a rational dietary source for the human diet. Saturated fats consumption is a wise choice in order to reduce the coronary heart disease risk, although it is believed in an opposite way. Researching through the healthiest tribes and knowing the biological function of saturated fats, and considering that eukaryotic cells need saturated fats to function properly, made this research important to conclude the rational dietary choice of edible fats and oils.
Inadequate long-chain omega-3 fatty acid status has a substantial impact on our health. Human RCT, observational, in vitro and in vivo animal studies all demonstrate that omega-3 fats from fish improve inflammatory regulation and its associated conditions. Yet, due to inconsistency in findings, the validity of omega-3 fatty acids as ‘treatments’ has been brought into question in the reporting of studies. To date, few studies have monitored the correlation between omega-3 dose, subsequent cellular enrichment of these fatty acids and clinical outcomes.
In this webinar, Dr Bailey presents the latest evidence for the importance of a biomarker-based, personalised approach to omega-3 treatment – one that significantly improves consistency in clinical outcomes and offers an antidote to the ‘one-size fits all’ approach that is responsible for significant individual variations in response in many published studies.
seminar in poultry nutrion by food additives.pptxmidoelzoghbfs94
The document discusses the effects of alpha-lipoic acid supplementation on broiler performance and physiology. It provides background on alpha-lipoic acid, including its forms, functions, and sources. It then reviews literature which has found that supplemental alpha-lipoic acid can improve broiler growth performance, antioxidant status, and serum biomarkers. Specifically, studies have shown increased weight gain, feed intake, antioxidant enzymes, glutathione levels, and decreased fat deposition and malondialdehyde levels with optimal supplemental levels of 50-100 mg/kg alpha-lipoic acid.
Nutritional Aspects of Raw Milk: A Beneficial or Hazardous Food Choice sami sami
This document provides an overview of the nutritional aspects and composition of raw milk. It discusses the macronutrients and micronutrients in milk such as protein, fat, lactose, and minerals. Milk fat is analyzed in more detail, outlining the different fatty acids present including saturated, monounsaturated, polyunsaturated, and conjugated linoleic acid. The potential health benefits and impacts of these fatty acids are also reviewed. The document then discusses the milk fat globule membrane and its potential health benefits based on in vitro studies inhibiting pathogenic bacterial adhesion and infection. Finally, the arguments for and against the consumption of raw versus pasteurized milk from a nutritional and food safety perspective are presented.
This document describes a study that developed a herbal cocktail to prevent stroke and cerebrovascular diseases. The study investigated the effects of a high fat diet on rats and the impact of treating the rats with extracts from four herbs: Artemisia Judaica, Panax ginseng, Salvia officinalis, and Polygonum multiflorum, both individually and combined in a cocktail. The herbal cocktail significantly lowered lipid levels, oxidative stress markers, and inflammatory mediators in the blood and liver compared to a high fat diet alone. The results suggest that the herbal cocktail has anti-hyperlipidemic and antioxidant effects and may help prevent obesity-related health problems like stroke.
Organic meat contains significantly higher levels of nutritionally desirable polyunsaturated and omega-3 fatty acids and lower levels of the potentially harmful saturated fatty acids myristic acid and palmitic acid compared to non-organic meat. This is likely due to differences in feeding practices required by organic standards which emphasize forage-based diets for livestock. Switching to organic meat could allow for a 30% reduction in meat consumption while maintaining omega-3 intake levels or a 50% increase in meat-based omega-3 intake at the same consumption level. Further research is still needed to fully understand compositional differences in individual meat types and a wider range of nutrients and compounds.
Omega-3 Polyunsaturated Fatty Acids and Metabolic SyndromeJosh Nooner
This document discusses research on the effects of omega-3 polyunsaturated fatty acids (PUFAs) on metabolic syndrome. Early epidemiological studies found lower rates of cardiovascular and inflammatory diseases in populations with high fish/omega-3 intake. Further studies showed that omega-3 supplementation improved metabolic abnormalities in rats and human subjects, reducing triglycerides, cholesterol, blood pressure, glucose, inflammation, and endothelial dysfunction. The document concludes that omega-3 PUFAs from fish oil supplements of 1-2g per day can effectively treat metabolic syndrome with minimal side effects.
This document discusses omega-3 fatty acids, specifically ALA, EPA, and DHA. It summarizes that ALA cannot be synthesized by humans and is considered essential. While the essentiality of EPA and DHA is debated, DHA is thought to be more essential due to its unique functions and role in visual and neural development. EPA and DHA can be synthesized from ALA, but conversion is inefficient so dietary intake is recommended. Fish are a rich source of EPA and DHA, and fish oil supplements are commonly used in research. However, contaminants in seafood are a health concern and can offset benefits.
1. Phytosterols are plant-derived compounds similar in structure to cholesterol that are found in plant oils and foods.
2. Consuming phytosterols reduces cholesterol absorption in the gut and lowers LDL cholesterol levels by around 10%.
3. The mechanisms by which phytosterols lower cholesterol involve interfering with cholesterol absorption from mixed micelles in the intestinal lumen and decreasing cholesterol solubility.
Weight reduction with improvement of serum lipid profile and ratios of Sesamu...lukeman Joseph Ade shittu
Development of novel natural dietary adjunct/agent with significant therapeutic effects on metabolic disease conditions such as obesity and heart disease raises concern in recent times. We studied chronic toxicity of the combined active ingredients present in the sesame leaves and their interaction on the fasting serum lipid profiles with their ratios in thirty adult male non-obese Sprague Dawley (SD) rats. Such that, both treated groups received 14.0 and 28.0 mg/kg body weight doses of aqueous leaves extract of Sesamum radiatum respectively on a daily basis via gastric gavage, while, the control received equal volume of normal saline daily for six weeks. Significant (P < 0.05) weight loss observed in the treated groups was associated with significant (P < 0.05) reductions in both serum cholesterol and triglycerides (TG). The effect on the serum lipoprotein cholesterol components and ratios were significant in a dose related manner, such that increase in HDL accompanied a corresponding decrease in both LDL and LDL/HDL ratio. In addition, to increased in TG/HDL ratio. However, no significant differences in the relative reduction level of VLDL and triglycerides in the treated groups were found compared to control. Thus, LDL/HDL ratio is significantly a better indicator than the TG/HDL ratio in assessing the impact of sesame treatment with evidence of weight loss and hypolipidaemia especially in hypertensive heart diseases.
In this webinar Dr Bailey explains the molecular mechanisms involved in colorectal cancer (CRC), initiation and progression and focus on dietary factors known to increase risk or offer protection against CRC development.
The colonic epithelium undergoes a constant and rapid renewal and intestinal homeostasis must therefore be tightly regulated to ensure continued homeostasis. Nowadays it is clear that lifestyle factors (mainly smoking, composition of the diet, and physical activity) play a role in the aetiology of colon inflammation and cancer initiation and progression. Among the dietary compounds known to significantly influence colonic health are various types of fatty acids originating from both dietary fat and fibre. In this webinar Dr Bailey explores the mechanisms by which fatty acids are thought to increase or decrease colorectal cancer risk. She also presents the science and evidence behind the growing interest of the omega-3 fatty acid EPA as an adjuvant in cancer prevention and treatment.
Similar to Carne erba a review of fatty acid profiles and antioxidant content in grass fed and grain-fed beef (20)
This summary provides the key points from the document in 3 sentences:
The cooperative focuses on sustainable agriculture across various territories in Italy, working with farmers and local communities. It aims to promote local production and traditional methods, as well as autonomy and social values through collective management. The interview discusses the challenges of modernization and globalization, and how the cooperative seeks to address these through integrated practices supporting farmers, territories, and local economies.
Agro-ecology is defined as applying ecological principles to agriculture and food systems. It originated as a scientific concept but has expanded to include social and political dimensions. Agro-ecology aims to question dominant industrial agricultural models and globalized markets by promoting more sustainable practices. These include recycling biomass and nutrients, improving soils, reducing external inputs, optimizing biodiversity and interactions between ecosystem elements, integrating food production and environmental protection, and acknowledging both traditional and scientific knowledge. The principles of agro-ecology also emphasize participatory research, autonomy, and food sovereignty.
This newsletter provides updates on PAN Europe's projects regarding bees collapse, endocrine disrupting chemicals in food, and the Week Without Pesticides. It introduces new staff members Lucie Daniel and Isabelle Pinzauti and notes Martin Dermine has joined as the bee expert. It also summarizes a symposium on integrated pest management and sustainable agriculture held in Brussels. Articles discuss the need to reduce pesticide dependency and move towards more sustainable farming practices like crop rotation and legume production.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
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Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
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2. Daley et al. Nutrition Journal 2010, 9:10 Page 2 of 12
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However, more recent lipid research would suggest that products as well as to discuss the effects these specific
not all SFAs have the same impact on serum choles- nutrients have on human health.
terol. For instance, lauric acid (C12:0) and myristic acid
(C14:0), have a greater total cholesterol raising effect Review of fatty acid profiles in grass-fed beef
than palmitic acid (C16:0), whereas stearic acid (C18:0) Red meat, regardless of feeding regimen, is nutrient
has a neutral effect on the concentration of total serum dense and regarded as an important source of essential
cholesterol, including no apparent impact on either LDL amino acids, vitamins A, B 6 , B 12 , D, E, and minerals,
or HDL. Lauric acid increases total serum cholesterol, including iron, zinc and selenium [17,18]. Along with
although it also decreases the ratio of total cholesterol: these important nutrients, meat consumers also ingest a
HDL because of a preferential increase in HDL choles- number of fats which are an important source of energy
terol [5,7,9]. Thus, the individual fatty acid profiles tend and facilitate the absorption of fat-soluble vitamins
to be more instructive than broad lipid classifications including A, D, E and K. According to the ADA, animal
with respect to subsequent impacts on serum choles- fats contribute approximately 60% of the SFA in the
terol, and should therefore be considered when making American diet, most of which are palmitic acid (C16:0)
dietary recommendations for the prevention of CVD. and stearic acid (C18:0). Stearic acid has been shown to
Clearly the lipid hypothesis has had broad sweeping have no net impact on serum cholesterol concentrations
impacts; not only on the way we eat, but also on the in humans[17,19]. In addition, 30% of the FA content in
way food is produced on-farm. Indeed, changes in ani- conventionally produced beef is composed of oleic acid
mal breeding and genetics have resulted in an overall (C18:1) [20], a monounsaturated FA (MUFA) that elicits
leaner beef product[10]. Preliminary examination of a cholesterol-lowering effect among other healthful attri-
diets containing today’s leaner beef has shown a reduc- butes including a reduced risk of stroke and a significant
tion in serum cholesterol, provided that beef consump- decrease in both systolic and diastolic blood pressure in
tion is limited to a three ounce portion devoid of all susceptible populations [21].
external fat [11]. O’Dea’s work was the first of several Be that as it may, changes in finishing diets of conven-
studies to show today’s leaner beef products can reduce tional cattle can alter the lipid profile in such a way as
plasma LDL concentrations in both normal and hyper- to improve upon this nutritional package. Although
cholesterolemic subjects, theoretically reducing risk of there are genetic, age related and gender differences
CVD [12-15]. among the various meat producing species with respect
Beyond changes in genetics, some producers have also to lipid profiles and ratios, the effect of animal nutrition
altered their feeding practices whereby reducing or elim- is quite significant [22]. Regardless of the genetic
inating grain from the ruminant diet, producing a pro- makeup, gender, age, species or geographic location,
duct referred to as “grass-fed” or “grass-finished”. direct contrasts between grass and grain rations consis-
Historically, most of the beef produced until the 1940’s tently demonstrate significant differences in the overall
was from cattle finished on grass. During the 1950’s, fatty acid profile and antioxidant content found in the
considerable research was done to improve the effi- lipid depots and body tissues [22-24].
ciency of beef production, giving birth to the feedlot Table 1 summarizes the saturated fatty acid analysis
industry where high energy grains are fed to cattle as for a number of studies whose objectives were to con-
means to decrease days on feed and improve marbling trast the lipid profiles of cattle fed either a grain or
(intramuscular fat: IMF). In addition, U.S. consumers grass diets [25-31]. This table is limited to those studies
have grown accustomed to the taste of grain-fed beef, utilizing the longissimus dorsi (loin eye), thereby stan-
generally preferring the flavor and overall palatability dardizing the contrasts to similar cuts within the carcass
afforded by the higher energy grain ration[16]. However, and limits the comparisons to cattle between 20 and 30
changes in consumer demand, coupled with new months of age. Unfortunately, not all studies report data
research on the effect of feed on nutrient content, have in similar units of measure (i.e., g/g of fatty acid), so
a number of producers returning to the pastoral direct comparisons between studies are not possible.
approach to beef production despite the inherent Table 1 reports that grass finished cattle are typically
inefficiencies. lower in total fat as compared to grain-fed contempor-
Research spanning three decades suggests that grass- aries. Interestingly, there is no consistent difference in
only diets can significantly alter the fatty acid composi- total SFA content between these two feeding regimens.
tion and improve the overall antioxidant content of Those SFA’s considered to be more detrimental to
beef. It is the intent of this review, to synthesize and serum cholesterol levels, i.e., myristic (C14:0) and palmi-
summarize the information currently available to sub- tic (C16:0), were higher in grain-fed beef as compared
stantiate an enhanced nutrient claim for grass-fed beef to grass-fed contemporaries in 60% of the studies
3. Daley et al. Nutrition Journal 2010, 9:10 Page 3 of 12
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Table 1 Comparison of mean saturated fatty acid composition (expressed as mg/g of fatty acid or as a % of total
lipid) between grass-fed and grain-fed cattle
Fatty Acid
Author, publication year, breed, C12:0 C14:0 C16:0 C18:0 C20:0 Total SFA (units as Total lipid (units as
treatment lauric myristic palmitic stearic arachidic specified) specified)
Alfaia, et al., 2009, Crossbred g/100 g lipid
steers
Grass 0.05 1.24* 18.42* 17.54* 0.25* 38.76 9.76* mg/g muscle
Grain 0.06 1.84* 20.79* 14.96* 0.19* 39.27 13.03* mg/g muscle
Leheska, et al., 2008, Mixed cattle g/100 g lipid
Grass 0.05 2.84* 26.9 17.0* 0.13* 48.8* 2.8* % of muscle
Grain 0.07 3.45* 26.3 13.2* 0.08* 45.1* 4.4* % of muscle
Garcia et al., 2008, Angus X-bred % of total FA
steers
Grass na 2.19 23.1 13.1* na 38.4* 2.86* %IMF
Grain na 2.44 22.1 10.8* na 35.3* 3.85* %IMF
Ponnampalam, et al., 2006, Angus mg/100 g muscle tissue
steers
Grass na 56.9* 508* 272.8 na 900* 2.12%* % of muscle
Grain na 103.7* 899* 463.3 na 1568* 3.61%* % of muscle
Nuernberg, et al., 2005, Simmental % of total intramuscular fat reported as LSM
bulls
Grass 0.04 1.82 22.56* 17.64* na 43.91 1.51* % of muscle
Grain 0.05 1.96 24.26* 16.80* na 44.49 2.61* % of muscle
Descalzo, et al., 2005 Crossbred % of total FA
Steers
Grass na 2.2 22.0 19.1 na 42.8 2.7* %IMF
Grain na 2.0 25.0 18.2 na 45.5 4.7* %IMF
Realini, et al., 2004, Hereford % fatty acid within intramuscular fat
steers
Grass na 1.64* 21.61* 17.74* na 49.08 1.68* % of muscle
Grain na 2.17* 24.26* 15.77* na 47.62 3.18* % of muscle
*Indicates a significant difference (at least P < 0.05) between feeding regimens was reported within each respective study. “na” indicates that the value was not
reported in the original study.
reviewed. Grass finished meat contains elevated concen- of tissue [35]. Because pasture raised beef is lower in
trations of stearic acid (C18:0), the only saturated fatty overall fat [24-27,30], particularly with respect to mar-
acid with a net neutral impact on serum cholesterol. bling or IMF [26,36], it would seem to follow that
Thus, grass finished beef tends to produce a more favor- grass-finished beef would be lower in overall choles-
able SFA composition although little is known of how terol content although the data is very limited. Garcia
grass-finished beef would ultimately impact serum cho- et al (2008) report 40.3 and 45.8 grams of cholesterol/
lesterol levels in hyper-cholesterolemic patients as com- 100 grams of tissue in pastured and grain-fed steers,
pared to a grain-fed beef. respectively (P < 0.001) [24].
Like SFA intake, dietary cholesterol consumption has Interestingly, grain-fed beef consistently produces
also become an important issue to consumers. Inter- higher concentrations of MUFAs as compared to grass-
estingly, beef’s cholesterol content is similar to other fed beef, which include FAs such as oleic acid (C18:1
meats (beef 73; pork 79; lamb 85; chicken 76; and tur- cis-9), the primary MUFA in beef. A number of epide-
key 83 mg/100 g) [32], and can therefore be used miological studies comparing disease rates in different
interchangeably with white meats to reduce serum countries have suggested an inverse association between
cholesterol levels in hyper-cholesterolemic individuals MUFA intake and mortality rates to CVD [3,21]. Even
[11,33]. Studies have shown that breed, nutrition and so, grass-fed beef provides a higher concentration of
sex do not affect the cholesterol concentration of TVA (C18:1 t11), an important MUFA for de novo
bovine skeletal muscle, rather cholesterol content is synthesis of conjugated linoleic acid (CLA: C18:2 c-9,
highly correlated to IMF concentrations[34]. As IMF t-11), a potent anti-carcinogen that is synthesized within
levels rise, so goes cholesterol concentrations per gram the body tissues [37]. Specific information relative to the
4. Daley et al. Nutrition Journal 2010, 9:10 Page 4 of 12
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health benefits of CLA and its biochemistry will be Review of Omega-3: Omega-6 fatty acid content
detailed later. in grass-fed beef
The important polyunsaturated fatty acids (PUFAs) in There are two essential fatty acids (EFAs) in human
conventional beef are linoleic acid (C18:2), alpha-linole- nutrition: a-linolenic acid (aLA), an omega-3 fatty acid;
nic acid (C18:3), described as the essential FAs, and the and linoleic acid (LA), an omega-6 fatty acid. The
long-chain fatty acids including arachidonic acid human body cannot synthesize essential fatty acids, yet
(C20:4), eicosapentaenoic acid (C20:5), docosanpetaenoic they are critical to human health; for this reason, EFAs
acid (C22:5) and docosahexaenoic acid (C22:6) [38]. The must be obtained from food. Both aLA and LA are
significance of nutrition on fatty acid composition is polyunsaturated and serve as precursors of other impor-
clearly demonstrated when profiles are examined by tant compounds. For instance, aLA is the precursor for
omega 6 (n-6) and omega 3 (n-3) families. Table 2 the omega-3 pathway. Likewise, LA is the parent fatty
shows no significant change to the overall concentration acid in the omega-6 pathway. Omega-3 (n-3) and
of n-6 FAs between feeding regimens, although grass- omega-6 (n-6) fatty acids are two separate distinct
fed beef consistently shows a higher concentrations of families, yet they are synthesized by some of the same
n-3 FAs as compared to grain-fed contemporaries, creat- enzymes; specifically, delta-5-desaturase and delta-6-
ing a more favorable n-6:n-3 ratio. There are a number desaturase. Excess of one family of FAs can interfere
of studies that report positive effects of improved n-3 with the metabolism of the other, reducing its incor-
intake on CVD and other health related issues discussed poration into tissue lipids and altering their overall bio-
in more detail in the next section. logical effects [39]. Figure 1 depicts a schematic of n-6
Table 2 Comparison of mean polyunsatured fatty acid composition (expressed as mg/g of fatty acid or as a % of total
lipid) between grass-fed and grain-fed cattle
Fatty Acid
Author, publication C18:1 t11 C18:2 n-6 Total C18:3 n-3 C20:5n- C22:5n- C22:6n- Total Total Total Total n-6/n-
year, breed, treatment Vaccenic Linoleic CLA Linolenic 3 EPA 3 DPA 3 DHA PUFA MUFA n-6 n-3 3 ratio
Acid
Alfaia, et al., 2009, g/100 g lipid
Crossbred steers
Grass 1.35 12.55 5.14* 5.53* 2.13* 2.56* 0.20* 28.99* 24.69* 17.97* 10.41* 1.77*
Grain 0.92 11.95 2.65* 0.48* 0.47* 0.91* 0.11* 19.06* 34.99* 17.08 1.97* 8.99*
Leheska, et al., 2008, g/100 g lipid
Mixed cattle
Grass 2.95* 2.01 0.85* 0.71* 0.31 0.24* na 3.41 42.5* 2.30 1.07* 2.78*
Grain 0.51* 2.38 0.48* 0.13* 0.19 0.06* na 2.77 46.2* 2.58 0.19* 13.6*
Garcia, et al., 2008, Angus % of total FAs
steers
Grass 3.22* 3.41 0.72* 1.30* 0.52* 0.70* 0.43* 7.95 37.7* 5.00* 2.95* 1.72*
Grain 2.25* 3.93 0.58* 0.74* 0.12* 0.30* 0.14* 9.31 40.8* 8.05* 0.86* 10.38*
Ponnampalam, et al., mg/100 g muscle tissue
2006, Angus steers
Grass na 108.8* 14.3 32.4* 24.5* 36.5* 4.2 na 930* 191.6 97.6* 1.96*
Grain na 167.4* 16.1 14.9* 13.1* 31.6* 3.7 na 1729* 253.8 63.3* 3.57*
Nuernberg, et al., 2005, % of total fatty acids
Simmental bulls
Grass na 6.56 0.87* 2.22* 0.94* 1.32* 0.17* 14.29* 56.09 9.80 4.70* 2.04*
Grain na 5.22 0.72* 0.46* 0.08* 0.29* 0.05* 9.07* 55.51 7.73 0.90* 8.34*
Descalzo, et al., 2005, % of total FAs
Crossbred steers
Grass 4.2* 5.4 na 1.4* tr 0.6 tr 10.31* 34.17* 7.4 2.0 3.72*
Grain 2.8* 4.7 na 0.7* tr 0.4 tr 7.29* 37.83* 6.3 1.1 5.73*
Realini, et al., 2004, % fatty acid within intramuscular fat
Hereford steers
Grass na 3.29* 0.53* 1.34* 0.69* 1.04* 0.09 9.96* 40.96* na na 1.44*
Grain na 2.84* 0.25* 0.35* 0.30* 0.56* 0.09 6.02* 46.36* na na 3.00*
* Indicates a significant difference (at least P < 0.05) between feeding regimens within each respective study reported. “na” indicates that the value was not
reported in the original study. “tr” indicates trace amounts detected.
5. Daley et al. Nutrition Journal 2010, 9:10 Page 5 of 12
http://www.nutritionj.com/content/9/1/10
Figure 1 Linoleic (C18:2n-6) and a-Linolenic (C18:3n-3) Acid metabolism and elongation. (Adapted from Simopoulos et al., 1991)
and n-3 metabolism and elongation within the body The omega-3 fatty acids were first discovered in the
[40]. early 1970’s when Danish physicians observed that
A healthy diet should consist of roughly one to four Greenland Eskimos had an exceptionally low incidence
times more omega-6 fatty acids than omega-3 fatty of heart disease and arthritis despite the fact that they
acids. The typical American diet tends to contain 11 to consumed a diet high in fat. These early studies estab-
30 times more omega -6 fatty acids than omega -3, a lished fish as a rich source of n-3 fatty acids. More
phenomenon that has been hypothesized as a significant recent research has established that EPA and DHA play
factor in the rising rate of inflammatory disorders in the a crucial role in the prevention of atherosclerosis, heart
United States[40]. Table 2 shows significant differences attack, depression and cancer [40,42]. In addition,
in n-6:n-3 ratios between grass-fed and grain-fed beef, omega-3 consumption reduced the inflammation caused
with and overall average of 1.53 and 7.65 for grass-fed by rheumatoid arthritis [43,44].
and grain-fed, respectively, for all studies reported in The human brain has a high requirement for DHA;
this review. low DHA levels have been linked to low brain serotonin
The major types of omega-3 fatty acids used by the levels, which are connected to an increased tendency for
body include: a-linolenic acid (C18:3n-3, aLA), eicosa- depression and suicide. Several studies have established
pentaenoic acid (C20:5n-3, EPA), docosapentaenoic acid a correlation between low levels of omega -3 fatty acids
(C22:5n-3, DPA), and docosahexaenoic acid (C22:6n-3, and depression. High consumption of omega-3 FAs is
DHA). Once eaten, the body converts aLA to EPA, typically associated with a lower incidence of depression,
DPA and DHA, albeit at low efficiency. Studies generally a decreased prevalence of age-related memory loss and a
agree that whole body conversion of aLA to DHA is lower risk of developing Alzheimer’s disease [45-51].
below 5% in humans, the majority of these long-chain The National Institutes of Health has published recom-
FAs are consumed in the diet [41]. mended daily intakes of FAs; specific recommendations
6. Daley et al. Nutrition Journal 2010, 9:10 Page 6 of 12
http://www.nutritionj.com/content/9/1/10
include 650 mg of EPA and DHA, 2.22 g/day of aLA and Microbial biohydrogenation of LA and aLA by an
4.44 g/day of LA. However, the Institute of Medicine has anaerobic rumen bacterium Butyrivibrio fibrisolvens is
recommended DRI (dietary reference intake) for LA highly dependent on rumen pH [61]. Grain consump-
(omega-6) at 12 to 17 g and aLA (omega-3) at 1.1 to 1.6 tion decreases rumen pH, reducing B. fibrisolven activ-
g for adult women and men, respectively. Although sea- ity, conversely grass-based diets provide for a more
food is the major dietary source of n-3 fatty acids, a favorable rumen environment for subsequent bacterial
recent fatty acid intake survey indicated that red meat synthesis [62]. Rumen pH may help to explain the
also serves as a significant source of n-3 fatty acids for apparent differences in CLA content between grain and
some populations [52]. grass-finished meat products (see Table 2). De novo
Sinclair and co-workers were the first to show that beef synthesis of CLA from 11t-C18:1 TVA has been docu-
consumption increased serum concentrations of a num- mented in rodents, dairy cows and humans. Studies sug-
ber of n-3 fatty acids including, EPA, DPA and DHA in gest a linear increase in CLA synthesis as the TVA
humans [40]. Likewise, there are a number of studies that content of the diet increased in human subjects [63].
have been conducted with livestock which report similar The rate of conversion of TVA to CLA has been esti-
findings, i.e., animals that consume rations high in pre- mated to range from 5 to 12% in rodents to 19 to 30%
cursor lipids produce a meat product higher in the essen- in humans[64]. True dietary intake of CLA should
tial fatty acids [53,54]. For instance, cattle fed primarily therefore consider native 9c11t-C18:2 (actual CLA) as
grass significantly increased the omega-3 content of the well as the 11t-C18:1 (potential CLA) content of foods
meat and also produced a more favorable omega-6 to [65,66]. Figure 2 portrays de novo synthesis pathways of
omega-3 ratio than grain-fed beef [46,55-57]. CLA from TVA [37].
Table 2 shows the effect of ration on polyunsaturated Natural augmentation of CLA c9t11 and TVA within
fatty acid composition from a number of recent studies the lipid fraction of beef products can be accomplished
that contrast grass-based rations to conventional grain through diets rich in grass and lush green forages. While
feeding regimens [24-28,30,31]. Grass-based diets precursors can be found in both grains and lush green
resulted in significantly higher levels of omega-3 within forages, grass-fed ruminant species have been shown to
the lipid fraction of the meat, while omega-6 levels were produce 2 to 3 times more CLA than ruminants fed in
left unchanged. In fact, as the concentration of grain is confinement on high grain diets, largely due to a more
increased in the grass-based diet, the concentration of favorable rumen pH [34,56,57,67] (see Table 2).
n-3 FAs decreases in a linear fashion. Grass-finished The impact of feeding practices becomes even more
beef consistently produces a higher concentration of n-3 evident in light of recent reports from Canada which
FAs (without effecting n-6 FA content), resulting in a suggests a shift in the predominate trans C18:1 isomer
more favorable n-6:n-3 ratio. in grain-fed beef. Dugan et al (2007) reported that the
The amount of total lipid (fat) found in a serving of major trans isomer in beef produced from a 73% barley
meat is highly dependent upon the feeding regimen as grain diet is 10t-18:1 (2.13% of total lipid) rather than
demonstrated in Tables 1 and 2. Fat will also vary by 11t-18:1 (TVA) (0.77% of total lipid), a finding that is
cut, as not all locations of the carcass will deposit fat to not particularly favorable considering the data that
the same degree. Genetics also play a role in lipid meta- would support a negative impact of 10t-18:1 on LDL
bolism creating significant breed effects. Even so, the cholesterol and CVD [68,69].
effect of feeding regimen is a very powerful determinant Over the past two decades numerous studies have
of fatty acid composition. shown significant health benefits attributable to the
actions of CLA, as demonstrated by experimental animal
Review of conjugated linoleic acid (CLA) and models, including actions to reduce carcinogenesis,
trans vaccenic acid (TVA) in grass-fed beef atherosclerosis, and onset of diabetes [70-72]. Conju-
Conjugated linoleic acids make up a group of polyunsa- gated linoleic acid has also been reported to modulate
turated FAs found in meat and milk from ruminant ani- body composition by reducing the accumulation of adi-
mals and exist as a general mixture of conjugated pose tissue in a variety of species including mice, rats,
isomers of LA. Of the many isomers identified, the cis-9, pigs, and now humans [73-76]. These changes in body
trans-11 CLA isomer (also referred to as rumenic acid composition occur at ultra high doses of CLA, dosages
or RA) accounts for up to 80-90% of the total CLA in that can only be attained through synthetic supplemen-
ruminant products [58]. Naturally occurring CLAs origi- tation that may also produce ill side-effects, such as gas-
nate from two sources: bacterial isomerization and/or trointestinal upset, adverse changes to glucose/insulin
biohydrogenation of polyunsaturated fatty acids (PUFA) metabolism and compromised liver function [77-81].
in the rumen and the desaturation of trans-fatty acids in A number of excellent reviews on CLA and human
the adipose tissue and mammary gland [59,60]. health can be found in the literature [61,82-84].
7. Daley et al. Nutrition Journal 2010, 9:10 Page 7 of 12
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Figure 2 De novo synthesis of CLA from 11t-C18:1 vaccenic acid. (Adapted from Bauman et al., 1999)
Optimal dietary intake remains to be established for regarded in many countries around the world, it is also
CLA. It has been hypothesized that 95 mg CLA/day is associated with a healthier fatty acid profile and a higher
enough to show positive effects in the reduction of antioxidant content [89].
breast cancer in women utilizing epidemiological data Plant species, harvest methods, and season, all have
linking increased milk consumption with reduced breast significant impacts on the carotenoid content of forage.
cancer[85]. Ha et al. (1989) published a much more con- In the process of making silage, haylage or hay, as much
servative estimate stating that 3 g/day CLA is required as 80% of the carotenoid content is destroyed [90].
to promote human health benefits[86]. Ritzenthaler et Further, significant seasonal shifts occur in carotenoid
al. (2001) estimated CLA intakes of 620 mg/day for men content owing to the seasonal nature of plant growth.
and 441 mg/day for women are necessary for cancer Carotenes (mainly b-carotene) are precursors of reti-
prevention[87]. Obviously, all these values represent nol (Vitamin A), a critical fat-soluble vitamin that is
rough estimates and are mainly based on extrapolated important for normal vision, bone growth, reproduction,
animal data. What is clear is that we as a population do cell division, and cell differentiation [91]. Specifically, it
not consume enough CLA in our diets to have a signifi- is responsible for maintaining the surface lining of the
cant impact on cancer prevention or suppression. eyes and also the lining of the respiratory, urinary, and
Reports indicate that Americans consume between 150 intestinal tracts. The overall integrity of skin and
to 200 mg/day, Germans consumer slightly more mucous membranes is maintained by vitamin A, creat-
between 300 to 400 mg/day[87], and the Australians ing a barrier to bacterial and viral infection [15,92]. In
seem to be closer to the optimum concentration at 500 addition, vitamin A is involved in the regulation of
to 1000 mg/day according to Parodi (1994) [88]. immune function by supporting the production and
function of white blood cells [12,13].
Review of pro-Vitamin A/b-carotene in The current recommended intake of vitamin A is
grass-fed meat 3,000 to 5,000 IU for men and 2,300 to 4,000 IU for
Carotenoids are a family of compounds that are synthe- women [93], respectively, which is equivalent to 900 to
sized by higher plants as natural plant pigments. 1500 μg (micrograms) (Note: DRI as reported by the
Xanthophylls, carotene and lycopene are responsible for Institute of Medicine for non-pregnant/non-lactating
yellow, orange and red coloring, respectively. Ruminants adult females is 700 μg/day and males is 900 μg/day or
on high forage rations pass a portion of the ingested 2,300 - 3,000 I U (assuming conversion of 3.33 IU/μg).
carotenoids into the milk and body fat in a manner that While there is no RDA (Required Daily Allowance) for
has yet to be fully elucidated. Cattle produced under b-carotene or other pro-vitamin A carotenoids, the
extensive grass-based production systems generally have Institute of Medicine suggests consuming 3 mg of b-car-
carcass fat which is more yellow than their concentrate- otene daily to maintain plasma b-carotene in the range
fed counterparts caused by carotenoids from the lush associated with normal function and a lowered risk of
green forages. Although yellow carcass fat is negatively chronic diseases (NIH: Office of Dietary Supplements).
8. Daley et al. Nutrition Journal 2010, 9:10 Page 8 of 12
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The effects of grass feeding on beta-carotene content [102-105]. Vitamin E may also block the formation of
of beef was described by Descalzo et al. (2005) who nitrosamines, which are carcinogens formed in the sto-
found pasture-fed steers incorporated significantly mach from nitrates consumed in the diet. It may also
higher amounts of beta-carotene into muscle tissues as protect against the development of cancers by enhan-
compared to grain-fed animals [94]. Concentrations cing immune function [106]. In addition to the cancer
were 0.45 μg/g and 0.06 μg/g for beef from pasture and fighting effects, there are some observational studies
grain-fed cattle respectively, demonstrating a 7 fold that found lens clarity (a diagnostic tool for cataracts)
increase in b-carotene levels for grass-fed beef over the was better in patients who regularly used vitamin E
grain-fed contemporaries. Similar data has been [107,108]. The current recommended intake of vitamin
reported previously, presumably due to the high b-caro- E is 22 IU (natural source) or 33 IU (synthetic source)
tene content of fresh grasses as compared to cereal for men and women [93,109], respectively, which is
grains[38,55,95-97]. (see Table 3) equivalent to 15 milligrams by weight.
The concentration of natural a-tocopherol (vitamin E)
Review of Vitamin E/a-tocopherol in found in grain-fed beef ranged between 0.75 to 2.92 μg/
grass-fed beef g of muscle whereas pasture-fed beef ranges from 2.1 to
Vitamin E is also a fat-soluble vitamin that exists in 7.73 μg/g of tissue depending on the type of forage
eight different isoforms with powerful antioxidant activ- made available to the animals (Table 4). Grass finishing
ity, the most active being a-tocopherol [98]. Numerous increases a-tocopherol levels three-fold over grain-fed
studies have shown that cattle finished on pasture pro- beef and places grass-fed beef well within range of the
duce higher levels of a-tocopherol in the final meat pro- muscle a-tocopherol levels needed to extend the shelf-
duct than cattle fed high concentrate diets life of retail beef (3 to 4 μg a-tocopherol/gram tissue)
[23,28,94,97,99-101] (see Table 4). [110]. Vitamin E (a-tocopherol) acts post-mortem to
Antioxidants such as vitamin E protect cells against delay oxidative deterioration of the meat; a process by
the effects of free radicals. Free radicals are potentially which myoglobin is converted into brown metmyoglo-
damaging by-products of metabolism that may contri- bin, producing a darkened, brown appearance to the
bute to the development of chronic diseases such as meat. In a study where grass-fed and grain-fed beef
cancer and cardiovascular disease. were directly compared, the bright red color associated
Preliminary research shows vitamin E supplementation with oxymyoglobin was retained longer in the retail dis-
may help prevent or delay coronary heart disease play in the grass-fed group, even thought the grass-fed
meat contains a higher concentration of more oxidizable
Table 3 Comparison of mean b-carotene vitamin content n-3 PUFA. The authors concluded that the antioxidants
in fresh beef from grass-fed and grain-fed cattle in grass probably caused higher tissue levels of vitamin
b-carotene E in grazed animals with benefits of lower lipid oxida-
Author, year, animal class Grass-fed Grain-fed tion and better color retention despite the greater
(ug/g tissue) (ug/g tissue) potential for lipid oxidation[111].
Insani et al., 2007, Crossbred steers 0.74* 0.17*
Descalzo et al., 2005 Crossbred steers 0.45* 0.06* Review of antioxidant enzyme content in
Yang et al., 2002, Crossbred steers 0.16* 0.01* grass-fed beef
* Indicates a significant difference (at least P < 0.05) between feeding Glutathione (GT), is a relatively new protein identified in
regimens was reported within each respective study. foods. It is a tripeptide composed of cysteine, glutamic
acid and glycine and functions as an antioxidant primarily
Table 4 Comparison of mean a-tocopherol vitamin as a component of the enzyme system containing GT oxi-
content in fresh beef from grass-fed and grain-fed cattle dase and reductase. Within the cell, GT has the capability
a-tocopherol of quenching free radicals (like hydrogen peroxide), thus
Author, year, animal class Grass-fed Grain-fed protecting the cell from oxidized lipids or proteins and
(ug/g tissue) (ug/g tissue) prevent damage to DNA. GT and its associated enzymes
De la Fuente et al., 2009, Mixed cattle 4.07* 0.75* are found in virtually all plant and animal tissue and is
Descalzo, et al., 2008, Crossbred steers 3.08* 1.50* readily absorbed in the small intestine[112].
Insani et al., 2007, Crossbred steers 2.1* 0.8* Although our knowledge of GT content in foods is still
Descalzo, et al., 2005, Crosbred steers 4.6* 2.2* somewhat limited, dairy products, eggs, apples, beans, and
Realini et al., 2004, Hereford steers 3.91* 2.92* rice contain very little GT (< 3.3 mg/100 g). In contrast,
Yang et al., 2002, Crossbred steers 4.5* 1.8* fresh vegetables (e.g., asparagus 28.3 mg/100 g) and freshly
* Indicates a significant difference (at least P < 0.05) between feeding
cooked meats, such as ham and beef (23.3 mg/100 g and
regimens was reported within each respective study. 17.5 mg/100 g, respectively), are high in GT [113].
9. Daley et al. Nutrition Journal 2010, 9:10 Page 9 of 12
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Because GT compounds are elevated in lush green British lambs fed grass and Spanish lambs fed milk and
forages, grass-fed beef is particularly high in GT as com- concentrates were assessed by British and Spanish taste
pared to grain-fed contemporaries. Descalzo et al. (2007) panels, both found the British lamb to have a higher
reported a significant increase in GT molar concentra- odor and flavor intensity. However, the British panel
tions in grass-fed beef [114]. In addition, grass-fed sam- preferred the flavor and overall eating quality of the
ples were also higher in superoxide dismutase (SOD) grass-fed lamb, the Spanish panel much preferred the
and catalase (CAT) activity than beef from grain-fed Spanish fed lamb [120]. Likewise, the U.S. is well known
animals[115]. Superoxide dismutase and catalase are for producing corn-fed beef, taste panels and consumers
coupled enzymes that work together as powerful antiox- who are more familiar with the taste of corn-fed beef
idants, SOD scavenges superoxide anions by forming seem to prefer it as well [16]. An individual usually
hydrogen peroxide and CAT then decomposes the comes to prefer the foods they grew up eating, making
hydrogen peroxide to H 2 O and O 2 . Grass only diets consumer sensory panels more of an art than science
improve the oxidative enzyme concentration in beef, [36]. Trained taste panels, i.e., persons specifically
protecting the muscle lipids against oxidation as well as trained to evaluate sensory characteristics in beef, found
providing the beef consumer with an additional source grass-fed beef less palatable than grain-fed beef in flavor
of antioxidant compounds. and tenderness [119,121].
Issues related to flavor and palatability of Conclusion
grass-fed beef Research spanning three decades supports the argument
Maintaining the more favorable lipid profile in grass-fed that grass-fed beef (on a g/g fat basis), has a more desir-
beef requires a high percentage of lush fresh forage or able SFA lipid profile (more C18:0 cholesterol neutral
grass in the ration. The higher the concentration of SFA and less C14:0 & C16:0 cholesterol elevating SFAs)
fresh green forages, the higher the aLA precursor that as compared to grain-fed beef. Grass-finished beef is
will be available for CLA and n-3 synthesis [53,54]. also higher in total CLA (C18:2) isomers, TVA (C18:1
Fresh pasture forages have 10 to 12 times more C18:3 t11) and n-3 FAs on a g/g fat basis. This results in a
than cereal grains [116]. Dried or cured forages, such as better n-6:n-3 ratio that is preferred by the nutritional
hay, will have a slightly lower amount of precursor for community. Grass-fed beef is also higher in precursors
CLA and n-3 synthesis. Shifting diets to cereal grains for Vitamin A and E and cancer fighting antioxidants
will cause a significant change in the FA profile and such as GT and SOD activity as compared to grain-fed
antioxidant content within 30 days of transition [57]. contemporaries.
Because grass-finishing alters the biochemistry of the Grass-fed beef tends to be lower in overall fat content,
beef, aroma and flavor will also be affected. These attri- an important consideration for those consumers inter-
butes are directly linked to the chemical makeup of the ested in decreasing overall fat consumption. Because of
final product. In a study comparing the flavor com- these differences in FA content, grass-fed beef also pos-
pounds between cooked grass-fed and grain-fed beef, sesses a distinct grass flavor and unique cooking quali-
the grass-fed beef contained higher concentrations of ties that should be considered when making the
diterpenoids, derivatives of chlorophyll call phyt-1-ene transition from grain-fed beef. To maximize the favor-
and phyt-2-ene, that changed both the flavor and aroma able lipid profile and to guarantee the elevated antioxi-
of the cooked product [117]. Others have identified a dant content, animals should be finished on 100% grass
“green” odor from cooked grass-fed meat associated or pasture-based diets.
with hexanals derived from oleic and aLA FAs. In con- Grain-fed beef consumers may achieve similar intakes
trast to the “green” aroma, grain-fed beef was described of both n-3 and CLA through consumption of higher fat
as possessing a “soapy” aroma, presumably from the portions with higher overall palatability scores. A num-
octanals formed from LA that is found in high concen- ber of clinical studies have shown that today’s lean beef,
tration in grains [118]. Grass-fed beef consumers can regardless of feeding strategy, can be used interchange-
expect a different flavor and aroma to their steaks as ably with fish or skinless chicken to reduce serum cho-
they cook on the grill. Likewise, because of the lower lesterol levels in hypercholesterolemic patients.
lipid content and high concentration of PUFAs, cooking
time will be reduced. For an exhaustive look at the
Abbreviations
effect of meat compounds on flavor, see Calkins and c: cis; t: trans; FA: fatty acid; SFA: saturated fatty acid; PUFA: polyunsaturated
Hodgen (2007) [119]. fatty acid; MUFA: monounsaturated fatty acid; CLA: conjugated linoleic acid;
With respect to palatability, grass-fed beef has histori- TVA: trans-vaccenic acid; EPA: eicosapentaenoic acid; DPA: docosapentaenoic
acid; DHA: docosahexaenoic acid; GT: glutathione; SOD: superoxide
cally been less well accepted in markets where grain-fed dismutase; CAT: catalase.
products predominant. For example, in a study where
10. Daley et al. Nutrition Journal 2010, 9:10 Page 10 of 12
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Acknowledgements hypercholesterolemic men with different levels of habitual beef intake.
The authors would like to acknowledge Grace Berryhill for her assistance Experimental Biological Medicine 2002, 227(4):266-75.
with the figures, tables and editorial contributions to this manuscript. 16. Wood JD, Richardson RI, Nute GR, Fisher AV, Campo MM, Kasapidou E,
Sheard PR, Enser M: Effects of fatty acids on meat quality: review. Meat
Author details Science 2003, 66:21-32.
1
College of Agriculture, California State University, Chico, CA, USA. 2University 17. Williamson CS, Foster RK, Stanner SA, Buttriss JL: Red meat in the diet.
of California Cooperative Extension Service, Davis, CA, USA. British Nutrition Foundation. Nutrition Bulletin 2005, 30:323-335, Ref Type:
Report.
Authors’ contributions 18. Biesalski HK: Meat as a component of a healthy diet - are there any risks
CAD was responsible for the literature review, completed most of the or benefits if meat is avoided? Meat Science 2005, 70(3):509-24.
primary writing, created the manuscript and worked through the submission 19. Yu S, Derr J, Etherton TD, Kris-Etherton PM: Plasma cholesterol-predictive
process; AA conducted the literature search, organized the articles according equations demonstrate that stearic acid is neutral and monosaturated
to category, completed some of the primary writing and served as editor; fatty acids are hypocholesterolemic. American Journal of Clinical Nutrition
SPD conducted a portion of the literature review and served as editor for 1995, 61:1129-39.
the manuscript; GAN conducted a portion of the literature review and 20. Whetsell MS, Rayburn EB, Lozier JD: Human Health Effects of Fatty Acids
served as editor for the manuscript; SL conducted a portion o the literature in Beef. Fact Sheet: West Virgina University & U.S.D.A. Agriculture Research
review and served as editor for the manuscript. All authors read and Service. Extension Service West Virginia University 2003, Ref Type: Electronic
approved the final manuscript. Citation.
21. Kris-Etherton PM: Monounsaturated fatty acids and risk of cardiovascular
Competing interests disease. Circulation 1999, 100:1253.
The authors declare that they have no competing interests. 22. DeSmet S, Raes K, Demeyer D: Meat fatty acid composition as affected by
fatness and genetic factors: a review. Animal Research 2004, 53:81-98.
Received: 29 July 2009 Accepted: 10 March 2010 23. De la Fuente J, Diaz MT, Alvarez I, Oliver MA, Font i Furnols M, Sanudo C,
Published: 10 March 2010 Campo MM, Montossi F, Nute GR, Caneque V: Fatty acid and vitamin E
composition of intramuscular fat in cattle reared in different production
References systems. Meat Science 2009, 82:331-7.
1. Griel AE, Kris-Etherton PM: Beyond saturated fat: The importance of the 24. Garcia PT, Pensel NA, Sancho AM, Latimori NJ, Kloster AM, Amigone MA,
dietary fatty acid profile on cardiovascular disease. Nutrition Reviews 2006, Casal JJ: Beef lipids in relation to animal breed and nutrition in
64(5):257-62. Argentina. Meat Science 2008, 79:500-8.
2. Kris-Etherton PM, Innis S: Dietary Fatty Acids – Position of the American 25. Alfaia CPM, Alves SP, Martins SIV, Costa ASH, Fontes CMGA, Lemos JPC,
Dietetic Association and Dietitians of Canada. American Dietetic Bessa RJB, Prates JAM: Effect of feeding system on intramuscular fatty
Association Position Report. Journal of the American Dietetic Association 2007, acids and conjugated linoleic acid isomers of beef cattle, with emphasis
107(9):1599-1611, Ref Type: Report. on their nutritional value and discriminatory ability. Food Chemistry 2009,
3. Hu FB, Stampfer MJ, Manson JE, Rimm E, Colditz GA, Rosner BA, 114:939-46.
Hennekins CH, Willett WC: Dietary fat intake and the risk of coronary 26. Leheska JM, Thompson LD, Howe JC, Hentges E, Boyce J, Brooks JC,
heart disease in women. New England Journal of Medicine 1997, Shriver B, Hoover L, Miller MF: Effects of conventional and grass-feeding
337:1491-9. systems on the nutrient composition of beef. Journal Animal Science
4. Posner BM, Cobb JL, Belanger AJ, Cupples LA, D’Agostino RB, Stokes J: 2008, 86:3575-85.
Dietary lipid predictors of coronary heart disease in men. The 27. Nuernberg K, Dannenberger D, Nuernberg G, Ender K, Voigt J, Scollan ND,
Framingham Study. Archives of Internal Medicine 1991, 151:1181-7. Wood JD, Nute GR, Richardson RI: Effect of a grass-based and a
5. Mensink RP, Katan MB: Effect of dietary fatty acids on serum lipids and concentrate feeding system on meat quality characteristics and fatty
lipoproteins. Arteriosclerosis Thrombosis Vascular Biology 1992, 12:911-9. acid composition of longissimus muscle in different cattle breeds.
6. Keys A: Coronary heart disease in seven countries. Circulation 1970, Livestock Production Science 2005, 94:137-47.
41(1):211. 28. Realini CE, Duckett SK, Brito GW, Rizza MD, De Mattos D: Effect of pasture
7. Mensink RP, Zock PL, Kester AD, Katan MB: Effects of dietary fatty acids vs. concentrate feeding with or without antioxidants on carcass
and carbohydrates on the ratio of serum total HDL cholesterol and on characteristics, fatty acid composition, and quality of Uruguayan beef.
serum lipids and apolipoproteins: A meta-analysis of 60 controlled trials. Meat Science 2004, 66:567-77.
American Journal of Clinical Nutrition 2003, 77:1146-55. 29. Warren HE, Enser M, Richardson I, Wood JD, Scollan ND: Effect of breed
8. Putnam J, Allshouse J, Scott-Kantor L: U.S. per capita food supply trends: and diet on total lipid and selected shelf-life parameters in beef muscle.
More calories, refined carbohydrates, and fats. Food Review 2002, Proceedings of British Society of animal science 2003, 23.
25(3):2-15. 30. Ponnampalam EN, Mann NJ, Sinclair AJ: Effect of feeding systems on
9. Kris-Etherton PMYS: Individual fatty acid effects on plasma lipids and omega-3 fatty acids, conjugated linoleic acid and trans fatty acids in
lipoproteins. Human studies. American Journal of Clinical Nutrition 1997, Australian beef cuts, potential impact on human health. Asia Pacific
65(suppl.5):1628S-44S. Journal of Clinical Nutrition 2006, 15(1):21-9.
10. Higgs JD: The changing nature of red meat: 20 years improving 31. Descalzo A, Insani EM, Biolatto A, Sancho AM, Garcia PT, Pensel NA:
nutritional quality. Trends in Food Science and Technology 2000, 11:85-95. Influence of pasture or grain-based diets supplemented with vitamin E
11. O’Dea K, Traianedes K, Chisholm K, Leyden H, Sinclair AJ: Cholesterol- on antioxidant/oxidative balance of Argentine beef. Meat Science 2005,
lowering effect of a low-fat diet containing lean beef is reversed by the 70:35-44.
addition of beef fat. American Journal of Clinical Nutrition 1990, 52:491-4. 32. Wheeler TL, Davis GW, Stoecker BJ, Harmon CJ: Cholesterol concentrations
12. Beauchesne-Rondeau E, Gascon A, Bergeron J, Jacques H: Plasma lipids of longissimus muscle, subcutaneous fat and serum of two beef cattle
and lipoproteins in hypercholesterolemic men fed a lipid-lowering diet breed types. Journal of Animal Science 1987, 65:1531-7.
containing lean beef, lean fish, or poultry. American Journal of Clinical 33. Smith DR, Wood R, Tseng S, Smith SB: Increased beef consumption
Nutrition 2003, 77(3):587-93. increases apolipoprotein A-1 but not serum cholesterol of mildly
13. Melanson K, Gootman J, Myrdal A, Kline G, Rippe JM: Weight loss and total hypercholesterolemic men with different levels of habitual beef intake.
lipid profile changes in overweight women consuming beef or chicken Experimental Biological Medicine 2002, 227(4):266-75.
as the primary protein source. Nutrition 2003, 19:409-14. 34. Rule DC, Broughton KS, Shellito SM, Maiorano G: Comparison of muscle
14. Denke MA: Role of beef and beef tallow, an enriched source of stearic fatty acid profiles and cholesterol concentrations of bison, cattle, elk
acid, in a cholesterol-lowering diet. American Journal of Clinical Nutrition and chicken. Journal Animal Science 2002, 80:1202-11.
1994, 60:1044S-9S. 35. Alfaia CPM, Castro MLF, Martins SIV, Portugal APV, Alves SPA, Fontes CMGA:
15. Smith DR, Wood R, Tseng S, Smith SB: Increased beef consumption Influence of slaughter season and muscle type on faty acid composition,
increases lipoprotein A-I but not serum cholesterol of mildly
11. Daley et al. Nutrition Journal 2010, 9:10 Page 11 of 12
http://www.nutritionj.com/content/9/1/10
conjugated linoleic acid isomeric distribution and nutritional quality of 60. Sehat N, Rickert RR, Mossoba MM, Dramer JKG, Yurawecz MP, Roach JAG,
intramuscular fat in Arouquesa-PDO veal. Meat Science 2007, 76:787-95. Adlof RO, Morehouse KM, Fritsche J, Eulitz KD, Steinhart H, Ku K: Improved
36. Sitz BM, Calkins CR, Feuz DM, Umberger WJ, Eskridge KM: Consumer separation of conjugated fatty acid methyl esters by silver ion-high-
sensory acceptance and value of domestic, Canadian, and Australian performance liquid chromatography. Lipids 1999, 34:407-13.
grass-fed beef steaks. Journal of Animal Science 2005, 83:2863-8. 61. Pariza MW, Park Y, Cook ME: Mechanisms of action of conjugated linoleic
37. Bauman DE, Lock AL: Conjugated linoleic acid: biosynthesis and acid: evidence and speculation. Proceedings for the Society of Experimental
nutritional significance. Fox and McSweeney. Advanced Dairy Chemistry Biology and Medicine 2000, 32:853-8.
Springer, New York, 3 2006, , 2: 93-136, Ref Type: Serial (Book, Monograph). 62. Bessa RJB, Santos-Silva J, Ribeiro JMR, Portugal AV: Reticulo-rumen
38. Enser M, Hallett KG, Hewett B, Fursey GAJ, Wood JD, Harrington G: Fatty biohydrogenation and the enrichment of ruminant edible products with
acid content and composition of UK beef and lamb muscle in relation linoleic acid conjugated isomers. Livestock Production Science 2000,
to production system and implications for human nutrition. Meat Science 63:201-11.
1998, 49(3):329-41. 63. Turpeinen AM, Mutanen M, Aro ASI, Basu SPD, Griinar JM: Bioconversion of
39. Ruxton CHS, Reed SC, Simpson JA, Millington KJ: The health benefits of vaccenic acid to conjugated linoleic acid in humans. American Journal of
omega-3 polyunsaturated fatty acids: a review of the evidence. The Clinical Nutrition 2002, 76:504-10.
Journal of Human Nutrition and Dietetics 2004, 17:449-59. 64. Turpeinen AM, Mautanen M, Aro A, Salminen I, Basu S, Palmquist DL:
40. Simopoulos A: Omega-3 fatty acids in health and disease and in growth Bioconversion of vaccenic acid to conjugated linoleic acid in humans.
and development. American Journal of Clinical Nutrition 1991, 54:438-63. American Journal of Clinical Nutrition 2002, 76:504-10.
41. Thomas BJ: Efficiency of conversion of alpha-linolenic acid to long chain 65. Turpeinen AM, Mautanen M, Aro A, Salminen I, Basu S, Palmquist DL:
n-3 fatty acids in man. Current Opinion in Clincal Nutrition and Metabolic Bioconversion of vaccenic acid to conjugated linoleic acid in humans.
Care 2002, 5(2):127-32. American Journal of Clinical Nutrition 2002, 76:504-10.
42. Connor WE: Importance of n-3 fatty acids in health and disease. 66. Adlof RO, Duval S, Emken EA: Biosynthesis of conjugated linoleic acid in
American Journal of Clinical Nutrition 2000, 71:171S-5S. humans. Lipids 2000, 35:131-5.
43. Kremer JM, Lawrence DA, Jubiz W, Galli C, Simopoulos AP: Different doses 67. Mandell IB, Gullett JG, Buchanan-Smith JG, Campbell CP: Effects of diet
of fish -oil fatty acid ingestion in active rheumatoid arthritis: a and slaughter endpoint on carcass composition and beef quality in
prospective study of clinical and immunological parameters. Dietary Charolais cross steers fed alfalfa silage and (or) high concentrate diets.
Omega-3 and Omega-6 fatty acids: biological effects and nutritional Canadian Journal of Animal Science 1997, 77:403-14.
essentiality New York: Plenum Press 1989. 68. Dugan MER, Rollan DC, Aalhus JL, Aldai N, Kramer JKG: Subcutaneous fat
44. DiGiacomo RA, Kremer JM, Shah DM: Fish-oil dietary supplementation in composition of youthful and mature Canadian beef: emphasis on
patients with Raynaud’s Phenomenon: A double-blind, controlled, individual conjugated linoleic acid and trans-18:1 isomers. Canadian
prospective study. The American Journal of Medicine 1989, 86:158-64. Journal of Animal Science 2008, 88:591-9.
45. Kalmijn S: Dietary fat intake and the risk of incident dementia in the 69. Hodgson JM, Wahlqvist ML, Boxall JA, Balazs ND: Platelet trans fatty acids
Rotterdam Study. Annals of Neurology 1997, 42(5):776-82. in relation to angiographically assessed coronary artery disease.
46. Yehuda S, Rabinovtz S, Carasso RL, Mostofsky DI: Essential fatty acids Atherosclerosis 1996, 120:147-54.
preparation (SR-3) improves Alzheimer’s patient’s quality of life. 70. IP C, Scimeca JA, Thompson HJ: Conjugated linoleic acid. Cancer
International Journal of Neuroscience 1996, 87(3-4):141-9. Supplement 1994, 74(3):1050-4.
47. Hibbeln JR: Fish oil consumption and major depression. The Lancet 1998, 71. Kritchevsky D, Tepper SA, Wright S, Tso P, Czarnecki SK: Influence of
351:1213, (April 18 1998). conjugated linoleic acid (CLA) on establishment and progression of
48. Hibbeln JR, Salem N: Dietary polyunsaturated fatty acids and depression: atherosclerosis in rabbits. Journal American Collection of Nutrition 2000,
when cholesterol does not satisfy. American Journal of Clinical Nutrition 19(4):472S-7S.
1995, 62:1-9. 72. Steinhart H, Rickert R, Winkler K: Identification and analysis of conjugated
49. Stoll AL, et al: Omega 3 fatty acids in bipolar disorder. Archives of General linoleic acid isomers (CLA). European Journal of Medicine 1996, 20(8):370-2.
Psychiatry 1999, 56, 407-12-415-16. 73. Dugan MER, Aalhus JL, Jeremiah LE, Kramer JKG, Schaefer AL: The effects
50. Calabrese JR, Rapport DJ, Shleton MD: Fish oils and bipolar disorder. of feeding conjugated linoleic acid on subsequent port quality. Canadian
Archives of General Psychiatry 1999, 56:413-4. Journal of Animal Science 1999, 79:45-51.
51. Laugharne JDE: Fatty acids and schizophrenia. Lipids 1996, 31:S163-S165. 74. Park Y, Albright KJ, Liu W, Storkson JM, Cook ME, Pariza MW: Effect of
52. Sinclair AJ, Johnson L, O’Dea K, Holman RT: Diets rich in lean beef conjugated linoleic acid on body composition in mice. Lipids 1997,
increase arachidonic acid and long-chain omega 3 polyunsaturated fatty 32:853-8.
acid levels in plasma phospholipids. Lipids 1994, 29(5):337-43. 75. Sisk M, Hausman D, Martin R, Azain M: Dietary conjugated linoleic acid
53. Raes K, DeSmet S, Demeyer D: Effect of dietary fatty acids on reduces adiposity in lean but not obese Zucker rats. Journal of Nutrition
incorporation of long chain polyunsaturated fatty acids and conjugated 2001, 131:1668-74.
linoleic acid in lamb, beef and pork meat: a review. Animal Feed Science 76. Smedman A, Vessby B: Conjugated linoleic acid supplementation in
and Technology 2004, 113:199-221. humans - Metabolic effects. Journal of Nutrition 2001, 36:773-81.
54. Marmer WN, Maxwell RJ, Williams JE: Effects of dietary regimen and tissue 77. Tsuboyama-Kasaoka N, Takahashi M, Tanemura K, Kim HJ, Tange T,
site on bovine fatty acid profiles. Journal Animal Science 1984, 59:109-21. Okuyama H, Kasai M, Ikemoto SS, Ezaki O: Conjugated linoleic acid
55. Wood JD, Enser M: Factors influencing fatty acids in meat and the role of supplementation reduces adipose tissue by apoptosis and develops
antioxidants in improving meat quality. British Journal of Nutrition 1997, lipodystrophy in mice. Diabetes 2000, 49:1534-42.
78:S49-S60. 78. Clement L, Poirier H, Niot I, Bocher V, Guerre-Millo M, Krief B, Staels B,
56. French P, Stanton C, Lawless F, O’Riordan EG, Monahan FJ, Caffery PJ, Besnard P: Dietary trans-10, cis-12 conjugated linoleic acid induces
Moloney AP: Fatty acid composition, including conjugated linoleic acid hyperinsulemia and fatty liver in the mouse. Journal of Lipid Research
of intramuscular fat from steers offered grazed grass, grass silage or 2002, 43:1400-9.
concentrate-based diets. Journal Animal Science 2000, 78:2849-55. 79. Roche HM, Noone E, Sewter C, McBennett S, Savage D, Gibney MJ,
57. Duckett SK, Wagner DG, Yates LD, Dolezal HG, May SG: Effects of time on O’Rahilly S, Vidal-Plug AJ: Isomer-dependent metabolic effects of
feed on beef nutrient composition. Journal Animal Science 1993, conjugated linoleic acid: insights from molecular markers sterol
71:2079-88. regulatory element-binding protein 1c and LXR alpha. Diabetes 2002,
58. Nuernberg K, Nuernberg G, Ender K, Lorenz S, Winkler K, Rickert R, 51:2037-44.
Steinhart H: Omega-3 fatty acids and conjugated linoleic acids of 80. Riserus U, Arner P, Brismar K, Vessby B: Treatment with dietary trans 10 cis
longissimus muscle in beef cattle. European Journal of Lipid Science 12 conjugated linoleic acid causes isomer specific insulin resistance in
Technology 2002, 104:463-71. obese men with the metabolic syndrome. Diabetes Care 2002, 25:1516-21.
59. Griinari JM, Corl BA, Lacy SH, Chouinard PY, Nurmela KV, Bauman DE: 81. Delany JP, Blohm F, Truett AA, Scimeca JA, West DB: Conjugated linoleic
Conjugated linoleic acid is synthesized endogenoulsy in lactating dairy acid rapidly reduces body fat content in mice without affecting energy
cows by delta-9 desaturase. Journal of Nutrition 2000, 130:2285-91. intake. American Journal of Physiology 1999, 276(4 pt 2):R1172-R1179.
12. Daley et al. Nutrition Journal 2010, 9:10 Page 12 of 12
http://www.nutritionj.com/content/9/1/10
82. Kelley DS, Simon VA, Taylor PC, Rudolph IL, Benito P: Dietary 103. Jialal I, Fuller CJ: Effect of vitamin E, vitamin C and beta-carotene on LDL
supplementation with conjugated linoleic acid increased its oxidation and atherosclerosis. Canadian Journal of Cardiology 1995,
concentration in human peripheral blood mononuclear cells, but did 11(supplemental G):97G-103G.
not alter their function. Lipids 2001, 36:669-74. 104. Stampfer MJ, Hennekens CH, Manson JE, Colditz GA, Rosner B, Willett WC:
83. Whigham LD, Cook ME, Atkinson RL: Conjugated linoleic acid: Vitamin E consumption and the risk of coronary disease in women. New
Implications for human health. Pharmacological Research 2000, England Journal of Medicine 1993, 328(1444):1449.
42(6):503-10. 105. Knekt P, Reunanen A, Jarvinen R, Seppanen R, Heliovaara M, Aromaa A:
84. Schmid A, Collomb M, Sieber R, Bee G: Conjugated linoleic acid in meat Antioxidant vitamin intake and coronary mortality in a longitudinal
and meat products. A review Meat Science 2006, 73:29-41. population study. American Journal of Epidemiology 1994, 139:1180-9.
85. Knekt P, Jarvinen R, Seppanen R, Pukkala E, Aromaa A: Intake of dairy 106. Weitberg AB, Corvese D: Effects of vitamin E and beta-carotene on DNA
products and the risk of breast cancer. British Journal of Cancer 1996, strand breakage induced by tobacco-specific nitrosamines and
73:687-91. stimulated human phagocytes. Journal of Experimental Cancer Research
86. Ha YL, Grimm NK, Pariza MW: Newly recognized anticarcinogenic fatty 1997, 16:11-4.
acids: identification and quantification in natural and processed cheese. 107. Leske MC, Chylack LT Jr, He Q, Wu SY, Schoenfeld E, Friend J, Wolfe J:
Journal of Agricultural and Food Chemistry 1989, 37:75-81. Antioxidant vitamins and nuclear opacities: The longitudinal study of
87. Ritzenthaler KL, McGuire MK, Falen R, Shultz TD, Dasgupta N, McGuire MA: cataract. Ophthalmology 1998, 105:831-6.
Estimation of conjugated linoleic acid intake by written dietary 108. Teikari JM, Virtamo J, Rautalahi M, Palmgren J, Liestro K, Heinonen OP:
assessment methodologies underestimates actual intake evaluated by Long-term supplementation with alpha-tocopherol and beta-carotene
food duplicate methodology. Journal of Nutrition 2001, 131:1548-54. and age-related cataract. Acta Ophthalmologica Scandinavica 1997,
88. Parodi PW: Conjugated linoleic acid: an anticarcinogenic fatty acid 75:634-40.
present in milk fat (review). Australian Journal of Dairy Technology 1994, 109. Dietary guidelines Advisory Committee, Agricultural Research Service United
49(2):93-7. States Department of Agriculture USDA: Report of the dietary guidelines
89. Dunne PG, Monahan FJ, O’Mara FP, Moloney AP: Colour of bovine advisory committee on the dietary guidelines for Americans. Dietary
subcutaneous adipose tissue: A review of contributory factors, guidelines Advisory Committee 2000, Ref Type: Hearing.
associations with carcass and meat quality and its potential utility in 110. McClure EK, Belk KE, Scanga JA, Smith GC: Determination of appropriate
authentication of dietary history. Meat Science 2009, 81(1):28-45. Vitamin E supplementation levels and administration times to ensure
90. Chauveau-Duriot B, Thomas D, Portelli J, Doreau M: Carotenoids content in adequate muscle tissue alpha-tocopherol concentration in cattle
forages: variation during conservation. Renc Rech Ruminants 2005, 12:117. destined for the Nolan Ryan tender-aged beef program. Animal
91. Scott LW, Dunn JK, Pownell HJ, Brauchi DJ, McMann MC, Herd JA, Harris KB, Sciences Research Report. The Department of Animal Sciences, Colorado
Savell JW, Cross HR, Gotto AM Jr: Effects of beef and chicken State University 2002, Ref Type: Report.
consumption on plasma lipid levels in hypercholesterolemic men. 111. Yang A, Lanari MC, Brewster MJ, Tume RK: Lipid stability and meat colour
Archives of Internal Medicine 1994, 154(11):1261-7. of beef from pasture and grain-fed cattle with or without vitamin E
92. Hunninghake DB, Maki KC, Kwiterovick PO Jr, Davidson MH, Dicklin MR, supplement. Meat Science 2002, 60:41-50.
Kafonek SD: Incorporation of lean red meat National Cholesterol 112. Valencia E, Marin A, Hardy G: Glutathione - Nutritional and
Education Program Step I diet: a long-term, randomized clinical trial in Pharmacological Viewpoints: Part II. Nutraceuticals 2001, 17:485-6.
free-living persons with hypercholesterolemic. Journal of American 113. Valencia E, Marin A, Hardy G: Glutathione - Nutritional and Pharmacologic
Colleges of Nutrition 2000, 19(3):351-60. Viewpoints: Part IV. Nutraceuticals 2001, 17:783-4.
93. National Institute of Health Clinical Nutrition Center: Facts about dietary 114. Descalzo AM, Rossetti L, Grigioni G, Irurueta M, Sancho AM, Carrete J,
supplements: Vitamin A and Carotenoids. 2002, Ref Type: Pamphlet. Pensel NA: Antioxidant status and odor profile in fresh beef from
94. Descalzo AM, Insani EM, Biolatto A, Sancho AM, Garcia PT, Pensel NA, pasture or grain-fed cattle. Meat Science 2007, 75:299-307.
Josifovich JA: Influence of pasture or grain-based diets supplemented 115. Gatellier P, Mercier Y, Renerre M: Effect of diet finishing mode (pasture or
with vitamin E on antioxidant/oxidative balance of Argentine beef. mixed diet) on antioxidant status of Charolais bovine meat. Meat Science
Journal of Meat Science 2005, 70:35-44. 2004, 67:385-94.
95. Simonne AH, Green NR, Bransby DI: Consumer acceptability and beta- 116. French P, O’Riordan EG, Monahan FJ, Caffery PJ, Moloney AP: Fatty acid
carotene content of beef as related to cattle finishing diets. Journal of composition of intra-muscular tricylglycerols of steers fed autumn grass
Food Science 1996, 61:1254-6. and concentrates. Livestock Production Science 2003, 81:307-17.
96. Duckett SK, Pratt SL, Pavan E: Corn oil or corn grain supplementation to 117. Elmore JS, Warren HE, Mottram DS, Scollan ND, Enser M, Richardson RI: A
stters grazing endophyte-free tall fescue. II. Effects on subcutaneous comparison of the aroma volatiles and fatty acid compositions of grilled
fatty acid content and lipogenic gene expression. Journal of Animal beef muscle from Aberdeen Angus and Holstein-Friesian steers fed deits
Science 2009, 87:1120-8. based on silage or concentrates. Meat Science 2006, 68:27-33.
97. Yang A, Brewster MJ, Lanari MC, Tume RK: Effect of vitamin E 118. Lorenz S, Buettner A, Ender K, Nuernberg G, Papstein HJ, Schieberle P:
supplementation on alpha-tocopherol and beta-carotene concentrations Influence of keeping system on the fatty acid composition in the
in tissues from pasture and grain-fed cattle. Meat Science 2002, longissimus muscle of bulls and odorants formed after pressure-
60(1):35-40. cooking. European Food Research and Technology 2002, 214:112-8.
98. Pryor WA: Vitamin E and Carotenoid Abstracts- 1994 Studies of Lipid- 119. Calkins CR, Hodgen JM: A fresh look at meat flavor. Meat Science 2007,
Soluble Antioxidants. Vitamin E Research and Information Services 1996. 77:63-80.
99. Arnold RN, Scheller N, Arp KK, Williams SC, Beuge DR, Schaefer DM: Effect 120. Sanudo C, Enser ME, Campo MM, Nute GR, Maria G, Sierra I, Wood JD: Fatty
of long or short-term feeding of alfa-tocopherol acetate to Holstein and acid composition and sensory characteristics of lamb carcasses from
crossbred beef steers on performance, carcass characteristics, and beef Britain and Spain. Meat Science 2000, 54:339-46.
color stability. Journal Animal Science 1992, 70:3055-65. 121. Killinger KM, Calkins CR, Umberger WJ, Feuz DM, Eskridge KM: A
100. Descalzo AM, Sancho AM: A review of natural antioxidants and their comparison of consumer sensory acceptance and value of domestic
effects on oxidative status, odor and quality of fresh beef in Argentina. beef steaks and steaks form a branded, Argentine beef program. Journal
Meat Science 2008, 79:423-36. Animal Science 2004, 82:3302-7.
101. Insani EM, Eyherabide A, Grigioni G, Sancho AM, Pensel NA, Descalzo AM:
Oxidative stability and its relationship with natural antioxidants during doi:10.1186/1475-2891-9-10
refrigerated retail display of beef produced in Argentina. Meat Science Cite this article as: Daley et al.: A review of fatty acid profiles and
2008, 79:444-52. antioxidant content in grass-fed and grain-fed beef. Nutrition Journal
102. Lonn EM, Yusuf S: Is there a role for antioxidant vitamins in the 2010 9:10.
prevention of cardiovascular diseases? An update on epidemiological
and clinical trials data. Cancer Journal of Cardiology 1997, 13:957-65.