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Cardiovascular assessment
Yaser Alikhajeh
1
Cardiovascular assessment
• Cardiovascular disease is the leading killer for both men and women
among all racial and ethnic groups in the world wide. According to
the Centers for Disease Control (CDC) studies among coronary heart
disease (CAD) patients, 90% of patients have had prior exposure to at
least one heart disease risk factor that contributed to their disease.
2
• A thorough cardiovascular assessment will help to identify significant
factors that can influence cardiovascular health such as high blood
cholesterol, cigarette use, diabetes, or hypertension. Therefore, a
cardiovascular exam should be a part of every abbreviated and
complete assessment.
• Cardiovascular assessment An evaluation of the condition, function,
and abnormalities of the heart and circulatory system.
3
Past Health History
• It is important to ask questions about the patient’s past health history.
• The past health history should elicit information about the following
issues: (hypertension, elevated blood cholesterol or triglycerides, heart
murmurs, congenital heart disease, rheumatic fever or unexplained joint
pains as a child or youth, recurrent tonsillitis and anemia.
4
Current Lifestyle and Psychosocial Status
• Nutrition
• Smoking
• Alcohol
• Exercise
• Drugs
5
Family History
• Family history is an important factor used in identifying your patient’s
risk for certain cardiovascular diseases.
• Ask to patient about any cardiovascular family history such as
hypertension, obesity, diabetes, coronary artery disease, or sudden
death.
6
SLEEP AND REST
• Clues to worsening cardiac disease, especially HF, can be revealed by sleep-
related events. Determining where the patient sleeps or rests is important.
• Recent changes, such as sleeping upright in a chair instead of in bed,
increasing the number of pillows used, awakening short of breath at nigh,
or awakening with angina (nocturnal angina), are all indicative of
worsening HF.
7
When assessing the cardiovascular system, other systems, such as the
circulatory and respiratory systems, also need to be evaluated to
provide a comprehensive and holistic picture.
Use the fundamental technique of physical examination:
1. INSPECTION
2. PALPATION
3. AUSCULTATION
8
THE GENERAL PHYSICAL EXAMINATION
• General Appearance
Does the patient choose to avoid certain positions to reduce or eliminate pain?
Emaciation suggests chronic heart failure or another systemic disorder (e.g., malignancy,
infection). The vital signs, including temperature, pulse rate, blood pressure (in both arms),
respiratory rate, and peripheral oxygen saturation, dictate the pace and scope of the evaluation
and provide initial clues as to the presence of a cardiovascular disorder.
9
Common Manifestations of cardiovascular disease
Chest pain
Shortness of breath or dyspnea
Edema and weight gain
 Palpitations
Fatigue
Dizziness and syncope or loss of consciousnes
10
skin
Cyanosis Telangiectasias Hemochromatosis
Pseudoxanthoma elasticum Erythromelalgia Lymphangitis
11
Head and Neck
Mitral facies Relapsing polychondritis
12
Extremities
Osler’s nodes Janeway lesions Nial clubbing
13
Edema Homan’s sign Marfan syndrome
14
Chest and Abdomen
pectus carinatum pectus excavatum straight back syndrome
15
Risk factors of cardiovascular disorders
• Non-modifiable risk factors:
1.Positive family history for premature coronary artery disease
2. Increasing age
3. Gender (men and postmenopausal women)
4. Race (higher incidence in African Americans than in Caucasians)
16
Modifiable risk factors
• Hyperlipidemia
• Hypertension
• Cigarette smoking
• Elevated blood glucose level
• Obesity
• Physical inactivity
17
LABORATORY TESTS
To assist in diagnosing an acute MI.
To identify abnormalities in the blood that affect the prognosis of a patient with a
cardiac condition.
To assess the degree of inflammation.
To screen for risk factors associated with atherosclerotic coronary artery disease.
To determine baseline values before performing therapeutic interventions.
 To monitor serum levels of medications.
 To assess the effects of medications
To screen generally for abnormalities
18
Types of cardiac enzymes or cardiac biomarkers
• Troponin– contractile protein, two types:
• TROPONIN T: found in the cardiac and skeletal muscle, elevated
during kidney and skeletal muscle damage, early rise after 3-4 hours,
peak is 24 hours.
• TROPONIN I: found only in cardiac muscle, more specific but rises
later,4-6 hours, peak is at 18 hours.
Creatine Phosphokinase (CK-MB) is highly specific test for MI, elevation
of 4% and higher indicate MI.
• The time to rise is 4-6 hours, time to peak is 24 hours.
19
Lactic dehydrogenase(LDH)
• There is LDH1 and LDH2, normally LDH2 is greater than LDH1, if LDH1
is greater than LDH2 than the person is positive for MI.
• However increase in level occurs 48 to 72 hrs after the onset of
symptoms.
Myoglobin
• Myoglobin is a muscle protein with high sensitivity, but low specificity.
• Time to rise is 1-4 hours Peak time 6-12 hours.
20
BNP ( B- type natriuretic peptide) – BNP is synthesized in the
ventricular myocardium and released as a response to increased wall
stress.
An increased BNP level indicate patients at the risk of developing
sudden cardiac death.
C-reactive protein (CRP)
CRP is an inflammatory marker that may be an important risk factor
for atherosclerosis and ischemic heart disease.
CRP is an inflammatory marker produced by the liver in response to
systemic cytokinases.
Elevated CRP is associated with AMI, stroke, and the progression of
peripheral vascular disease.
21
Lipid profile [The risk of CAD increases
as the ratio of LDL to HDL or the ratio of
total cholesterol (LDL +HDL) to HDL
increases].
Cholesterol levels : Cholesterol is a lipid
required for hormone synthesis and cell
membrane formation
Parameters Normal Value Higher
CK-MB 5–25 IU/L >25 IU/L
TROPONIN I 0 - 0.10 >0.1 ng/I
CRP UP TO 3 > 3 mg/Iit
HDL 40-60 ˂ 40 mg/dI
LDL 130 160-189 mg/dI
Cholesterol <200 > 200 Mg/dI
LDH 140–280 IU/L >280 IU/L
22
Serum electrolyte levels
Sodium, potassium, and calcium are ions that are
vital to cellular depolarization and repolarization.
 In addition, the serum sodium concentration
reflects relative fluid balance.
 Generally, hyponatremia (low sodium level)
indicates fluid excess, and hypernatremia (high
sodium level) indicates fluid deficit
23
BLOOD UREA NITROGEN LEVEL (BUN)
• Blood urea nitrogen (BUN) is an end product of protein metabolism and is excreted
by the kidneys.
• In the patient with cardiac disease, an elevated BUN level may reflect reduced
renal perfusion (from decreased cardiac output) or intravascular fluid volume
deficit (from diuretic therapy or dehydration)
Parameters Normal Value Higher
BUN 6-20 mg/dL > 20 mg/dI
24
SERUM GLUCOSE LEVEL
• The serum glucose level is important to monitor, because many
patients with cardiac disease also have diabetes mellitus.
25
Coagulation Studies
26
Electrocardiogram (ECG)
• assess the heart’s electrical activity.
The standard 12-lead ECG is the most
commonly used tool to diagnose
dysrhythmias, conduction abnormalities,
enlarged heart chambers, myocardial
ischemia or infarction, high or low
calcium and potassium levels, and effects
of some medications.
27
28
29
30
Exercise Testing
• A Wide Variety Of Cardiovascular
Conditions
• Including Valvular Heart Disease
• Congenital Heart Disease
• Genetic Cardiovascular Conditions
• Arrhythmias
• Peripheral Arterial Disease (PAD).
31
• chest pain
• Functional capacity of the heart after
an MI or heart surgery
• Effectiveness of antianginal or
antiarrhythmic medications
• Dysrhythmias that occur during
physical exercise
• specific goals for a physical fitness
program. For cardiac rehabilitation
32
Contraindications to cardiac stress testing
• severe aortic stenosis
• acute myocarditis or pericarditis
• severe hypertension.
• CAD
• HF
• unstable angina
• Because complications associated with stress
testing can be life-threatening (MI, cardiac arrest,
HF, and severe dysrhythmias)
33
Fletcher GF, Ades PA, Kligfield P, et al: Exercise standards for testing and training: a scientific
statement from the American Heart Association. Circulation 128:873, 2013.
34
35
Morise AP, Lauer MS, Froelicher VF: Development and validation of a simple exercise test score for
use in women with symptoms of suspected coronary artery disease. Am Heart J 144:818, 2002.
36
Echocardiography
37
Echocardiography
• The first test of choice for assessing cardiac structure and function in
most clinical situations. It is a particularly useful tool for diagnosing
pericardial effusions, determining the etiology of heart murmurs,
evaluating the function of prosthetic heart valves, determining
chamber size, and evaluating ventricular wall motion.
38
Chest Radiograph in Cardiovascular Disease(CXR)
39
• The chest X-ray is a noninvasive tool used to visualize internal
structures, such as the heart, lungs, soft tissues, and bones.
• A chest x-ray usually is obtained to determine the size, contour, and
position of the heart.
• It does not help diagnose acute MI but can help diagnose some
complications (e.g., HF).
• Correct placement of cardiac catheters, such as pacemakers and
pulmonary artery catheters, is also confirmed by chest x-ray.
40
Nuclear Cardiology
• Nuclear cardiology studies use noninvasive
techniques to assess myocardial blood flow,
evaluate the pumping function of the heart
as well as visualize the size and location of
a heart attack. Among the techniques of
nuclear cardiology, myocardial perfusion
imaging is the most widely used.
41
Cardiovascular Magnetic Resonance Imaging((MRI)
• provides morphologic and functional information relevant to a broad
array of cardiovascular diseases.
42
Cardiac Computed Tomography
• arterial wall left ventricular (LV) and
right ventricular (RV)
• systolic function
• cardiac valve morphology
43
Holter monitor
• The Holter monitor is a type of portable
electrocardiogram (ECG). It records the
electrical activity of the heart
continuously over 24 hours or longer
while you are away from the doctor's
office. A standard or "resting" ECG is one
of the simplest and fastest tests used to
evaluate the heart.
44
Invasive cardiac diagnostic procedures..
• Cardiac catheterization
• Angiography
• Hemodynamic monitoring
• A) central venous pressure monitoring
• B) pulmonary artery pressure monitoring
• C) intra-arterial blood pressure monitoring
45
Cardiac catheterization
46
• Pressures and oxygen saturations in the four heart chambers are
measured.
• Cardiac catheterization is used to diagnose CAD, assess coronary
artery patency, and determine the extent of atherosclerosis based on
the percentage of coronary artery obstruction.
• These results determine whether revascularization procedures
including PTCA or coronary artery bypass surgery may be of benefit to
the client.
47
Indications & contra indications to cardiac catheterization
• Angiography is usually combined with heart catheterization for
coronary artery visualization.
• Contraindications for cardiac catheterization include:
1. Uncontrolled ventricular irritability.
2. Uncorrected electrolyte hyperkalemia, hypokalemia, hypercalcemia,
or hypocalcemia.
3. Digoxin toxicity.
4. Decompensated heart failure.
5. Severe renal insufficiency or anuria, unless renal dialysis will be
performed following procedure
48
Relative contraindications for cardiac catheterization
• Recent stroke (within the past month).
• Active GI bleeding.
• Active infection.
• Uncontrolled hypertension.
• Patient's refusal of therapeutic intervention
49
Coronary arteriography
50
Coronary angiography
• Coronary angiography is interventional diagnostic procedure in which
a radio contrast is injected directly into the coronary arteries, allowing
visualization and quantification of stenosis and/or obstruction.
51
HEMODYNAMIC MONITORING
Critically ill patients require continuous assessment of their cardiovascular
system to diagnose and manage their complex medical conditions.
This is most commonly achieved by the use of direct pressure monitoring
systems, often referred to as hemodynamic monitoring.
 Central venous pressure (CVP), pulmonary artery pressure, and intra-
arterial BP monitoring are common form of hemodynamic monitoring.
Hemodynamic monitoring is the assessment of the patient's circulatory
status; it includes measurements of heart rate, intra-arterial pressure, PAP,
and pulmonary capillary wedge pressure (PCWP), central venous pressure
(CVP), CO, and blood volume.
52
53
Reynolds Risk Score
• If you are a healthy woman or man without diabetes, the Reynolds
Risk Score is designed to predict your risk of having a future heart
attack, stroke, or other major heart disease in the next 10 years. In
addition to your age, blood pressure, cholesterol levels and whether
you currently smoke, the Reynolds Risk Score uses information from
two other risk factors, a blood test called hsCRP (a measure of
inflammation) and whether or not either of your parents had a heart
attack before they reached age 60 (a measure of genetic risk).
54
55
56
Reference
• De Koning L, Merchant AT, Pogue J, Anand SS: Waist circumference and waist to hip ratio as predictors of
cardiovascular events: Meta-regression analysis of prospective studies. Eur Heart J 28:850, 2007.
• Morise AP, Lauer MS, Froelicher VF: Development and validation of a simple exercise test score for use in
women with symptoms of suspected coronary artery disease. Am Heart J 144:818, 2002.
• Fletcher GF, Ades PA, Kligfield P, et al: Exercise standards for testing and training: a scientific statement from
the American Heart Association. Circulation 128:873, 2013.
• Maria Odette Gore et al: Combining Biomarkers and Imaging for Short-Term Assessment of
Cardiovascular Disease Risk in Apparently Healthy Adults.J Am Heart Assoc. 2020 Aug
4;9(15):e015410. doi: 10.1161/JAHA.119.015410. Epub 2020 Jul 23.
• Braunwald’s Heart Disease_ A Textbook of Cardiovascular Medicine.10th edition. 2015
57
58

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Cardiovascular aessessment

  • 2. Cardiovascular assessment • Cardiovascular disease is the leading killer for both men and women among all racial and ethnic groups in the world wide. According to the Centers for Disease Control (CDC) studies among coronary heart disease (CAD) patients, 90% of patients have had prior exposure to at least one heart disease risk factor that contributed to their disease. 2
  • 3. • A thorough cardiovascular assessment will help to identify significant factors that can influence cardiovascular health such as high blood cholesterol, cigarette use, diabetes, or hypertension. Therefore, a cardiovascular exam should be a part of every abbreviated and complete assessment. • Cardiovascular assessment An evaluation of the condition, function, and abnormalities of the heart and circulatory system. 3
  • 4. Past Health History • It is important to ask questions about the patient’s past health history. • The past health history should elicit information about the following issues: (hypertension, elevated blood cholesterol or triglycerides, heart murmurs, congenital heart disease, rheumatic fever or unexplained joint pains as a child or youth, recurrent tonsillitis and anemia. 4
  • 5. Current Lifestyle and Psychosocial Status • Nutrition • Smoking • Alcohol • Exercise • Drugs 5
  • 6. Family History • Family history is an important factor used in identifying your patient’s risk for certain cardiovascular diseases. • Ask to patient about any cardiovascular family history such as hypertension, obesity, diabetes, coronary artery disease, or sudden death. 6
  • 7. SLEEP AND REST • Clues to worsening cardiac disease, especially HF, can be revealed by sleep- related events. Determining where the patient sleeps or rests is important. • Recent changes, such as sleeping upright in a chair instead of in bed, increasing the number of pillows used, awakening short of breath at nigh, or awakening with angina (nocturnal angina), are all indicative of worsening HF. 7
  • 8. When assessing the cardiovascular system, other systems, such as the circulatory and respiratory systems, also need to be evaluated to provide a comprehensive and holistic picture. Use the fundamental technique of physical examination: 1. INSPECTION 2. PALPATION 3. AUSCULTATION 8
  • 9. THE GENERAL PHYSICAL EXAMINATION • General Appearance Does the patient choose to avoid certain positions to reduce or eliminate pain? Emaciation suggests chronic heart failure or another systemic disorder (e.g., malignancy, infection). The vital signs, including temperature, pulse rate, blood pressure (in both arms), respiratory rate, and peripheral oxygen saturation, dictate the pace and scope of the evaluation and provide initial clues as to the presence of a cardiovascular disorder. 9
  • 10. Common Manifestations of cardiovascular disease Chest pain Shortness of breath or dyspnea Edema and weight gain  Palpitations Fatigue Dizziness and syncope or loss of consciousnes 10
  • 11. skin Cyanosis Telangiectasias Hemochromatosis Pseudoxanthoma elasticum Erythromelalgia Lymphangitis 11
  • 12. Head and Neck Mitral facies Relapsing polychondritis 12
  • 13. Extremities Osler’s nodes Janeway lesions Nial clubbing 13
  • 14. Edema Homan’s sign Marfan syndrome 14
  • 15. Chest and Abdomen pectus carinatum pectus excavatum straight back syndrome 15
  • 16. Risk factors of cardiovascular disorders • Non-modifiable risk factors: 1.Positive family history for premature coronary artery disease 2. Increasing age 3. Gender (men and postmenopausal women) 4. Race (higher incidence in African Americans than in Caucasians) 16
  • 17. Modifiable risk factors • Hyperlipidemia • Hypertension • Cigarette smoking • Elevated blood glucose level • Obesity • Physical inactivity 17
  • 18. LABORATORY TESTS To assist in diagnosing an acute MI. To identify abnormalities in the blood that affect the prognosis of a patient with a cardiac condition. To assess the degree of inflammation. To screen for risk factors associated with atherosclerotic coronary artery disease. To determine baseline values before performing therapeutic interventions.  To monitor serum levels of medications.  To assess the effects of medications To screen generally for abnormalities 18
  • 19. Types of cardiac enzymes or cardiac biomarkers • Troponin– contractile protein, two types: • TROPONIN T: found in the cardiac and skeletal muscle, elevated during kidney and skeletal muscle damage, early rise after 3-4 hours, peak is 24 hours. • TROPONIN I: found only in cardiac muscle, more specific but rises later,4-6 hours, peak is at 18 hours. Creatine Phosphokinase (CK-MB) is highly specific test for MI, elevation of 4% and higher indicate MI. • The time to rise is 4-6 hours, time to peak is 24 hours. 19
  • 20. Lactic dehydrogenase(LDH) • There is LDH1 and LDH2, normally LDH2 is greater than LDH1, if LDH1 is greater than LDH2 than the person is positive for MI. • However increase in level occurs 48 to 72 hrs after the onset of symptoms. Myoglobin • Myoglobin is a muscle protein with high sensitivity, but low specificity. • Time to rise is 1-4 hours Peak time 6-12 hours. 20
  • 21. BNP ( B- type natriuretic peptide) – BNP is synthesized in the ventricular myocardium and released as a response to increased wall stress. An increased BNP level indicate patients at the risk of developing sudden cardiac death. C-reactive protein (CRP) CRP is an inflammatory marker that may be an important risk factor for atherosclerosis and ischemic heart disease. CRP is an inflammatory marker produced by the liver in response to systemic cytokinases. Elevated CRP is associated with AMI, stroke, and the progression of peripheral vascular disease. 21
  • 22. Lipid profile [The risk of CAD increases as the ratio of LDL to HDL or the ratio of total cholesterol (LDL +HDL) to HDL increases]. Cholesterol levels : Cholesterol is a lipid required for hormone synthesis and cell membrane formation Parameters Normal Value Higher CK-MB 5–25 IU/L >25 IU/L TROPONIN I 0 - 0.10 >0.1 ng/I CRP UP TO 3 > 3 mg/Iit HDL 40-60 ˂ 40 mg/dI LDL 130 160-189 mg/dI Cholesterol <200 > 200 Mg/dI LDH 140–280 IU/L >280 IU/L 22
  • 23. Serum electrolyte levels Sodium, potassium, and calcium are ions that are vital to cellular depolarization and repolarization.  In addition, the serum sodium concentration reflects relative fluid balance.  Generally, hyponatremia (low sodium level) indicates fluid excess, and hypernatremia (high sodium level) indicates fluid deficit 23
  • 24. BLOOD UREA NITROGEN LEVEL (BUN) • Blood urea nitrogen (BUN) is an end product of protein metabolism and is excreted by the kidneys. • In the patient with cardiac disease, an elevated BUN level may reflect reduced renal perfusion (from decreased cardiac output) or intravascular fluid volume deficit (from diuretic therapy or dehydration) Parameters Normal Value Higher BUN 6-20 mg/dL > 20 mg/dI 24
  • 25. SERUM GLUCOSE LEVEL • The serum glucose level is important to monitor, because many patients with cardiac disease also have diabetes mellitus. 25
  • 27. Electrocardiogram (ECG) • assess the heart’s electrical activity. The standard 12-lead ECG is the most commonly used tool to diagnose dysrhythmias, conduction abnormalities, enlarged heart chambers, myocardial ischemia or infarction, high or low calcium and potassium levels, and effects of some medications. 27
  • 28. 28
  • 29. 29
  • 30. 30
  • 31. Exercise Testing • A Wide Variety Of Cardiovascular Conditions • Including Valvular Heart Disease • Congenital Heart Disease • Genetic Cardiovascular Conditions • Arrhythmias • Peripheral Arterial Disease (PAD). 31
  • 32. • chest pain • Functional capacity of the heart after an MI or heart surgery • Effectiveness of antianginal or antiarrhythmic medications • Dysrhythmias that occur during physical exercise • specific goals for a physical fitness program. For cardiac rehabilitation 32
  • 33. Contraindications to cardiac stress testing • severe aortic stenosis • acute myocarditis or pericarditis • severe hypertension. • CAD • HF • unstable angina • Because complications associated with stress testing can be life-threatening (MI, cardiac arrest, HF, and severe dysrhythmias) 33
  • 34. Fletcher GF, Ades PA, Kligfield P, et al: Exercise standards for testing and training: a scientific statement from the American Heart Association. Circulation 128:873, 2013. 34
  • 35. 35
  • 36. Morise AP, Lauer MS, Froelicher VF: Development and validation of a simple exercise test score for use in women with symptoms of suspected coronary artery disease. Am Heart J 144:818, 2002. 36
  • 38. Echocardiography • The first test of choice for assessing cardiac structure and function in most clinical situations. It is a particularly useful tool for diagnosing pericardial effusions, determining the etiology of heart murmurs, evaluating the function of prosthetic heart valves, determining chamber size, and evaluating ventricular wall motion. 38
  • 39. Chest Radiograph in Cardiovascular Disease(CXR) 39
  • 40. • The chest X-ray is a noninvasive tool used to visualize internal structures, such as the heart, lungs, soft tissues, and bones. • A chest x-ray usually is obtained to determine the size, contour, and position of the heart. • It does not help diagnose acute MI but can help diagnose some complications (e.g., HF). • Correct placement of cardiac catheters, such as pacemakers and pulmonary artery catheters, is also confirmed by chest x-ray. 40
  • 41. Nuclear Cardiology • Nuclear cardiology studies use noninvasive techniques to assess myocardial blood flow, evaluate the pumping function of the heart as well as visualize the size and location of a heart attack. Among the techniques of nuclear cardiology, myocardial perfusion imaging is the most widely used. 41
  • 42. Cardiovascular Magnetic Resonance Imaging((MRI) • provides morphologic and functional information relevant to a broad array of cardiovascular diseases. 42
  • 43. Cardiac Computed Tomography • arterial wall left ventricular (LV) and right ventricular (RV) • systolic function • cardiac valve morphology 43
  • 44. Holter monitor • The Holter monitor is a type of portable electrocardiogram (ECG). It records the electrical activity of the heart continuously over 24 hours or longer while you are away from the doctor's office. A standard or "resting" ECG is one of the simplest and fastest tests used to evaluate the heart. 44
  • 45. Invasive cardiac diagnostic procedures.. • Cardiac catheterization • Angiography • Hemodynamic monitoring • A) central venous pressure monitoring • B) pulmonary artery pressure monitoring • C) intra-arterial blood pressure monitoring 45
  • 47. • Pressures and oxygen saturations in the four heart chambers are measured. • Cardiac catheterization is used to diagnose CAD, assess coronary artery patency, and determine the extent of atherosclerosis based on the percentage of coronary artery obstruction. • These results determine whether revascularization procedures including PTCA or coronary artery bypass surgery may be of benefit to the client. 47
  • 48. Indications & contra indications to cardiac catheterization • Angiography is usually combined with heart catheterization for coronary artery visualization. • Contraindications for cardiac catheterization include: 1. Uncontrolled ventricular irritability. 2. Uncorrected electrolyte hyperkalemia, hypokalemia, hypercalcemia, or hypocalcemia. 3. Digoxin toxicity. 4. Decompensated heart failure. 5. Severe renal insufficiency or anuria, unless renal dialysis will be performed following procedure 48
  • 49. Relative contraindications for cardiac catheterization • Recent stroke (within the past month). • Active GI bleeding. • Active infection. • Uncontrolled hypertension. • Patient's refusal of therapeutic intervention 49
  • 51. Coronary angiography • Coronary angiography is interventional diagnostic procedure in which a radio contrast is injected directly into the coronary arteries, allowing visualization and quantification of stenosis and/or obstruction. 51
  • 52. HEMODYNAMIC MONITORING Critically ill patients require continuous assessment of their cardiovascular system to diagnose and manage their complex medical conditions. This is most commonly achieved by the use of direct pressure monitoring systems, often referred to as hemodynamic monitoring.  Central venous pressure (CVP), pulmonary artery pressure, and intra- arterial BP monitoring are common form of hemodynamic monitoring. Hemodynamic monitoring is the assessment of the patient's circulatory status; it includes measurements of heart rate, intra-arterial pressure, PAP, and pulmonary capillary wedge pressure (PCWP), central venous pressure (CVP), CO, and blood volume. 52
  • 53. 53
  • 54. Reynolds Risk Score • If you are a healthy woman or man without diabetes, the Reynolds Risk Score is designed to predict your risk of having a future heart attack, stroke, or other major heart disease in the next 10 years. In addition to your age, blood pressure, cholesterol levels and whether you currently smoke, the Reynolds Risk Score uses information from two other risk factors, a blood test called hsCRP (a measure of inflammation) and whether or not either of your parents had a heart attack before they reached age 60 (a measure of genetic risk). 54
  • 55. 55
  • 56. 56
  • 57. Reference • De Koning L, Merchant AT, Pogue J, Anand SS: Waist circumference and waist to hip ratio as predictors of cardiovascular events: Meta-regression analysis of prospective studies. Eur Heart J 28:850, 2007. • Morise AP, Lauer MS, Froelicher VF: Development and validation of a simple exercise test score for use in women with symptoms of suspected coronary artery disease. Am Heart J 144:818, 2002. • Fletcher GF, Ades PA, Kligfield P, et al: Exercise standards for testing and training: a scientific statement from the American Heart Association. Circulation 128:873, 2013. • Maria Odette Gore et al: Combining Biomarkers and Imaging for Short-Term Assessment of Cardiovascular Disease Risk in Apparently Healthy Adults.J Am Heart Assoc. 2020 Aug 4;9(15):e015410. doi: 10.1161/JAHA.119.015410. Epub 2020 Jul 23. • Braunwald’s Heart Disease_ A Textbook of Cardiovascular Medicine.10th edition. 2015 57
  • 58. 58