Can you please help with the questions. 1. Which type of signaling DOES NOT involve a soluble signal molecule? a) endocrine b) paracrine c) neuronal d) contact dependent 2. Which statement conceming signal transduction is true? a) Cells can only respond to one signal at a time. b) Each cell has exactly one type of receptor, present in multiple copies. c) Signal transduction usually occurs in a single step. d) The biological response to a given ligand may not be the same in each cell. e) None of these answers are true. 3. Receptors involved in signaling can be found a) in the plasma membrane b) in the nucleus c) in the cytosol or the plasma membrane d) in the cytosol, nucleus or plasma membrane 4. Which of the following applies to second messengers? a) usually activate kinases b) amplify the signal from a membrane receptor c) can be cAMP or Ca++ d) are small molecules or ions that are soluble in the cytosol e) All of these answers. 5. Which second messenger is NOT soluble? a) calcium b) IP3 c) DAG d) CAMP 6. This type of cell surface receptor alters the membrane potential. a) ion channel receptor b) G protein-coupled receptors c) enzyme-coupled receptors d) none of these answers e) all of these answers.