Seeking sponsor support in exchange for licensing options for enzymes to produce bio-plastic concept.

1. Seeking Sponsored Research / License Optionsfor Bio-Plastic Concept 7/19/2011 1

2. Introduction C2 Biotechnologies, LLC Formed for profit, 2006 DoE SBIR Funded Strong background in molecular biology Low overhead costs Using biotechnology to improve the quality of life 7/19/2011 2

3. Project Summary Clone enzyme activities that convert furfural and derivatives into plastic. Combine enzyme activities into 1 protein (Plasticzyme). Offer Plasticzymeas new industrial enzyme for cellulosic pre-fermentation treatment alternative. 7/19/2011 3

4. Problem Cellulosic biomass pre-treatment produces fermentation (yeast) inhibitors. Removal of fermentation inhibitors required but cost time and money. Converting fermentation inhibitors into plastic creates new product and improves process economics. 7/19/2011 4

5. Objectives Demonstrate Protein Chemistry Build Fusion Enzyme Demonstrate Fusion Enzyme Activity 7/19/2011 5

6. Key Benefits Incremental innovation Cellulosic Co-product Development New Industrial Enzyme Cellulosic processing increasing Bio-plastic market is growing 7/19/2011 6

7. Statement of Work Milestone I: Demonstrate Chemistry - ~$300K Milestone II: Construct Fusion Enzyme -~$150K Milestone III: Demonstrate Fusion Enzyme Activity - ~$150K 7/19/2011 7

8. Project Timetable Estimated 2 year operation. 7/19/2011 8

9. Estimated Sponsor Support Requested Estimated budget for total project. 7/19/2011 9

10. Key Personnel Dr. Cosenza will oversee team Dr. Cosenza Research Assistant 1 Research Assistant 2 Research Assistant 3 7/19/2011 10

11. Evaluation Project will be evaluated in the form of milestones with go or no go decision points. Definable actions with anticipated outcomes form basis for project decisions-i.e. chemistry produces bio-plastic…go to next step. Written approval from sponsor required for project progression 7/19/2011 11

12. Return on Investment Option to license technology Commercial sources of “Plasticzyme” not available Bio-plastic market growing Global market at $2.7 billion* *E-zine: Environmental Leader, “Global BioplasticsMarket to Surpass $11 Billion by 2015”, posted 2/3/2011 7/19/2011 12

13. Contact Information 7/19/2011 13 Dr. Larry Cosenza C2 Biotechnologies, LLC 4663 Route 9G Germantown, NY 12526 Telephone: (518)537-7678 E-mail: lcosenza@c2biotechnologies.com