Natural Orifice Surgery (NOS) is a minimally invasive surgical technique that does not require any external incisions. It allows procedures to be performed through the mouth or other natural openings of the body. NOS offers benefits over traditional laparoscopic surgery such as less pain, fewer risks of infection or herniation, faster recovery times, and smaller scars. The StomaphyX system is one device that uses an endoscopic approach and detachable fasteners to perform tissue folding procedures transorally without incisions.