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By: Guadalupe Solis
     Period 2
Standards
Unit 6: Genetic Variation & Evolution
ļ‚² 7b Students know why alleles that are lethal in a homozygous individual may
  be carried in a heterozygote and thus maintained in the gene pool.

-   People who have/had brain tumor(s), can pass on genetics of them either
    from their relatives from generation to generation & when they have
    children(s), then could be a possibility they can have brain tumor(s).

Unit 3: Mutations & Biotechnology
ļ‚² 4c Students know how mutations in the DNA sequence of a gene may or may
  not affect the expression of the gene, or the sequence of amino acids in an
  encoded protein.

- .
What is a     A tumor is an abnormal
              growth of body tissue.
tumor ?       And also a tumor can be
              either not serious or
              harmful or cancerous or
              deadly.

            ā€¢ Either type may require
              therapy to remove it or
              reduce its size.
Lists Of Tumors
ā€¢ Brain tumor is an
What is a brain tumor     abnormal growth
?                         tissue in the brain.
                        ā€¢ The tumor can
                          either originate in
                          the brain itself
                          (primary brain
                          tumor), or come
                          from another part
                          of the body and
                          travel to the brain
                          (metastatic or
                          secondary tumor).
First, primary brain
How Does It   tumor are those that
              start in the brain, or
Happen ?      near to the brain. These
              can happen in the
              skull, in the cranial
              nerves, as well as in the
              brain
              membrane, pituitary
              gland and pineal
              gland. In primary brain
              tumors, there is no
              other source of cancer
              or tumors within the
              rest of the body.
Different Types Of Tumors
    There are many types of brain tumors. The first way to divide brain
    tumors is based on whether they are primary or secondary :

    Primary brain tumors are tumors that begin in the brain.

ā€¢   Primary brain tumors can be divided based on what type of cell the
    tumor began. Some primary brain tumor types are
    meningioma, ependymoma, pineal tumors, germ cell tumors, etc.
    The name of a tumor depends in part on what kind of cell it comes
    from. They can also be named for the tumor location within the
    brain.

    Secondary brain tumors are tumors that started our elsewhere in the
    body and spread, or metastasized, to the brain.

ā€¢   For example, secondary brain tumors could have begun as breast or
    lung cancer.
Meningioma
What is
Meningioma?
ā€¢ Meningioma are the
  second most common
  primary neoplasm
  (brain tumor) of the
  central nervous
  system.
Ependymoma
What is ependymoma?
ā€¢ Ependymoma is a tumor
  that arises from the
  ependyma, a tissue of the
  central nervous system.
The Causes
ā€¢ There are no known
  environmental causes for
  ependymomas, but there
  have been a number of
  mutations in the genes in the
  patients that are diagnosed
  with the disease.
Pinealoma
What is
Pinealoma?
ā€¢ Pinealoma is a tumor
  of the pineal gland.
Symptoms
ā€¢    Other symptoms
     may include
     hydrocephalus, gait
     disturbances, and
     precocious puberty.
What are the risks for
having brain tumors?
The risks for having brain tumors are:

ā€¢ Your age: Your risk of a brain tumor increases as you
  age

ā€¢ Chemical exposure on the job: People working in
  certain industries may HAVE an increased risk of brain
  tumors, possibly because of the chemicals they're
  exposed to on the job.

ā€¢ Family history: A small portion of brain tumors occur
  in people with a family history of brain tumors or a
  family history of genetic syndromes.
Symptoms              The
                       symptoms
The Symptoms of a      of brain
brain tumor are:       tumors
ā€¢ Headaches            depend
ā€¢ Nausea or vomiting
ā€¢ Problems balancing
                       on tumor
  or walking           size, type,
ā€¢ Problems with        and
  memory               location.
Images :

ā€¢   Dvorak (7 October 2007) ā€œTumor Pineocytoma1ā€ Photo. Wikiepedia.org
    http://upload.wikimedia.org/wikipedia/commons/3/37/Tumor_Pineocytoma1.
    JPG

ā€¢   Glitzy queen00 (ā€¦2007) ā€œContrast enhanced meningiomaā€ Photo.
    Wikipedia.org
    http://en.wikipedia.org/wiki/File:Contrast_enhanced_meningioma.jpg

ā€¢   Klaus D. Peter, Gummersbach, Germany (ā€¦2007) ā€œHidradenomaā€ Photo.
    Wikipedia.org
    http://upload.wikimedia.org/wikipedia/commons/e/eb/Hidradenoma.jpg

ā€¢   Marvin 101 (26.02.2008) ā€œ Hirnmetastasā€ Photo. Wikipedia.org
    http://upload.wikimedia.org/wikipedia/commons/5/5f/Hirnmetastase_MRT-
    T1_KM.jpg

ā€¢   Unknown author (Unknown) ā€œEpendymoma_01ā€ Photo. Google.com
    http://neurosurgery.ucla.edu/images/Ependymoma_01.jpg
References

ā€¢   Charles Patrick Davis, MD, PhD &Melissa Conrad Stƶppler, MD, Chief Medical Editor (ā€¦2011)
    ā€œBrain Cancer causesā€ http://www.emedicinehealth.com/brain_cancer/page2_em.htm

ā€¢   James Black (2005-2011) ā€œWhat are brain tumorsā€ http://www.siweds.com/Basics/whatIs-
    tumor.html

ā€¢   Souhami, et al. Oxford Textbook of Oncology. 2nd edition. 2002. Oxford University
    Press, Raghavan, et al. The Textbook of Uncommon Cancers. 3rd edition. 2006. Wiley, Levin.
    Cancer in the Nervous System. 2nd edition. 2002. Oxford University Press, Tonn, et al. Neuro-
    oncology of CNS tumours. 2006. Springer, De Vita, et al. Cancer: Principles & Practice of
    Oncology. 8th edition. 2008. Lippincott, Williams and Wilkins, Improving Outcomes for People
    with Brain and Other CNS Tumours - The Manual. 2006.National Institute for Health and Clinical
    Excellence (NICE). Unknown Author (Nov. 1, 2011) ā€œEpendyomaā€
    http://www.macmillan.org.uk/Cancerinformation/Cancertypes/Brain/Typesofbraintumours/Epen
    dymoma.aspx

ā€¢   Unknown Author (1997-2011) ā€œBrain Cancerā€
    http://www.providence.org/losangeles/services/cancer/treatment/brain.htm

ā€¢   Unknown Author (ā€¦2011) ā€œBrain Tumor Symptomsā€http://www.brain-tumor-symptoms.org/

    Unknown Author (1996-2011) ā€œBrain Tumor (cont.)ā€
    http://www.medicinenet.com/brain_tumor/page5.htm

    Unknown Author (ā€¦2011) ā€œBrain Tumor FAQā€ http://www.braintumor.org/patients-family-
    friends/about-brain-tumors/brain-tumor-faq.html
ā€¢ Unknown Author (2008-2011) ā€œBrain Tumor Typesā€
http://www.fightplga.org/about/brain_tumor_types
ā€¢ Unknown Author (ā€¦2011) ā€œMeningiomaā€ http://brain-
tumor.org/73_meningioma.html
ā€¢

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Brain Tumor(1)

  • 2. Standards Unit 6: Genetic Variation & Evolution ļ‚² 7b Students know why alleles that are lethal in a homozygous individual may be carried in a heterozygote and thus maintained in the gene pool. - People who have/had brain tumor(s), can pass on genetics of them either from their relatives from generation to generation & when they have children(s), then could be a possibility they can have brain tumor(s). Unit 3: Mutations & Biotechnology ļ‚² 4c Students know how mutations in the DNA sequence of a gene may or may not affect the expression of the gene, or the sequence of amino acids in an encoded protein. - .
  • 3. What is a A tumor is an abnormal growth of body tissue. tumor ? And also a tumor can be either not serious or harmful or cancerous or deadly. ā€¢ Either type may require therapy to remove it or reduce its size.
  • 5. ā€¢ Brain tumor is an What is a brain tumor abnormal growth ? tissue in the brain. ā€¢ The tumor can either originate in the brain itself (primary brain tumor), or come from another part of the body and travel to the brain (metastatic or secondary tumor).
  • 6. First, primary brain How Does It tumor are those that start in the brain, or Happen ? near to the brain. These can happen in the skull, in the cranial nerves, as well as in the brain membrane, pituitary gland and pineal gland. In primary brain tumors, there is no other source of cancer or tumors within the rest of the body.
  • 7. Different Types Of Tumors There are many types of brain tumors. The first way to divide brain tumors is based on whether they are primary or secondary : Primary brain tumors are tumors that begin in the brain. ā€¢ Primary brain tumors can be divided based on what type of cell the tumor began. Some primary brain tumor types are meningioma, ependymoma, pineal tumors, germ cell tumors, etc. The name of a tumor depends in part on what kind of cell it comes from. They can also be named for the tumor location within the brain. Secondary brain tumors are tumors that started our elsewhere in the body and spread, or metastasized, to the brain. ā€¢ For example, secondary brain tumors could have begun as breast or lung cancer.
  • 8. Meningioma What is Meningioma? ā€¢ Meningioma are the second most common primary neoplasm (brain tumor) of the central nervous system.
  • 9. Ependymoma What is ependymoma? ā€¢ Ependymoma is a tumor that arises from the ependyma, a tissue of the central nervous system. The Causes ā€¢ There are no known environmental causes for ependymomas, but there have been a number of mutations in the genes in the patients that are diagnosed with the disease.
  • 10. Pinealoma What is Pinealoma? ā€¢ Pinealoma is a tumor of the pineal gland. Symptoms ā€¢ Other symptoms may include hydrocephalus, gait disturbances, and precocious puberty.
  • 11. What are the risks for having brain tumors? The risks for having brain tumors are: ā€¢ Your age: Your risk of a brain tumor increases as you age ā€¢ Chemical exposure on the job: People working in certain industries may HAVE an increased risk of brain tumors, possibly because of the chemicals they're exposed to on the job. ā€¢ Family history: A small portion of brain tumors occur in people with a family history of brain tumors or a family history of genetic syndromes.
  • 12. Symptoms The symptoms The Symptoms of a of brain brain tumor are: tumors ā€¢ Headaches depend ā€¢ Nausea or vomiting ā€¢ Problems balancing on tumor or walking size, type, ā€¢ Problems with and memory location.
  • 13. Images : ā€¢ Dvorak (7 October 2007) ā€œTumor Pineocytoma1ā€ Photo. Wikiepedia.org http://upload.wikimedia.org/wikipedia/commons/3/37/Tumor_Pineocytoma1. JPG ā€¢ Glitzy queen00 (ā€¦2007) ā€œContrast enhanced meningiomaā€ Photo. Wikipedia.org http://en.wikipedia.org/wiki/File:Contrast_enhanced_meningioma.jpg ā€¢ Klaus D. Peter, Gummersbach, Germany (ā€¦2007) ā€œHidradenomaā€ Photo. Wikipedia.org http://upload.wikimedia.org/wikipedia/commons/e/eb/Hidradenoma.jpg ā€¢ Marvin 101 (26.02.2008) ā€œ Hirnmetastasā€ Photo. Wikipedia.org http://upload.wikimedia.org/wikipedia/commons/5/5f/Hirnmetastase_MRT- T1_KM.jpg ā€¢ Unknown author (Unknown) ā€œEpendymoma_01ā€ Photo. Google.com http://neurosurgery.ucla.edu/images/Ependymoma_01.jpg
  • 14. References ā€¢ Charles Patrick Davis, MD, PhD &Melissa Conrad Stƶppler, MD, Chief Medical Editor (ā€¦2011) ā€œBrain Cancer causesā€ http://www.emedicinehealth.com/brain_cancer/page2_em.htm ā€¢ James Black (2005-2011) ā€œWhat are brain tumorsā€ http://www.siweds.com/Basics/whatIs- tumor.html ā€¢ Souhami, et al. Oxford Textbook of Oncology. 2nd edition. 2002. Oxford University Press, Raghavan, et al. The Textbook of Uncommon Cancers. 3rd edition. 2006. Wiley, Levin. Cancer in the Nervous System. 2nd edition. 2002. Oxford University Press, Tonn, et al. Neuro- oncology of CNS tumours. 2006. Springer, De Vita, et al. Cancer: Principles & Practice of Oncology. 8th edition. 2008. Lippincott, Williams and Wilkins, Improving Outcomes for People with Brain and Other CNS Tumours - The Manual. 2006.National Institute for Health and Clinical Excellence (NICE). Unknown Author (Nov. 1, 2011) ā€œEpendyomaā€ http://www.macmillan.org.uk/Cancerinformation/Cancertypes/Brain/Typesofbraintumours/Epen dymoma.aspx ā€¢ Unknown Author (1997-2011) ā€œBrain Cancerā€ http://www.providence.org/losangeles/services/cancer/treatment/brain.htm ā€¢ Unknown Author (ā€¦2011) ā€œBrain Tumor Symptomsā€http://www.brain-tumor-symptoms.org/ Unknown Author (1996-2011) ā€œBrain Tumor (cont.)ā€ http://www.medicinenet.com/brain_tumor/page5.htm Unknown Author (ā€¦2011) ā€œBrain Tumor FAQā€ http://www.braintumor.org/patients-family- friends/about-brain-tumors/brain-tumor-faq.html
  • 15. ā€¢ Unknown Author (2008-2011) ā€œBrain Tumor Typesā€ http://www.fightplga.org/about/brain_tumor_types ā€¢ Unknown Author (ā€¦2011) ā€œMeningiomaā€ http://brain- tumor.org/73_meningioma.html ā€¢