This case report describes the successful treatment of a patient's severe tinnitus caused by stapedius myoclonus (involuntary muscle spasms) using local injections of botulinum toxin type A (Botox). The patient experienced relief from tinnitus within two days of receiving Botox placed near the stapedius muscle through a perforation in her eardrum. The tinnitus did not return for three months. When it recurred at four months, a second Botox treatment again provided rapid relief. The report concludes that local Botox injections may be an effective treatment for tinnitus caused by stapedius or other muscle spasms in the ear.