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Biochemistry
                          Chapter 3

         Mr. Hunter
           Biology
Kennedy High School 10/18/2011
Biology
                  Mr. Hunter
                  10/23/2012
• Objectives
• SWBAT
• Analyze the structure of carbohydrates, proteins,
  lipids and nucleic acids.
• Identify polymer and monomer units and their
  construction process
Bell Ringer 03/19/2013 - Biology


1.   What are the independent
     and dependent variables?
2.   On which axis is the
     dependent variable
     located on?
3.   On which axis is the
     independent variable on?
4.   At what time is the
     temperature approximately
      80 degrees?
Carbon Compounds
• All compounds can be
  classified into two
  categories: Organic and
  Inorganic
• Most matter in living
  organisms that is not
  water is made of
  organic compounds.
• Organic compounds are
  made of carbon atoms.
• Inorganic compounds
  do not contain carbon
  atoms.
Carbon Compounds
• Carbon atoms are able
  to form 4 covalent
  bonds with other atoms
  of different elements.
• Carbon can bond in
  different ways to
  produce molecules of
  different shapes. pg. 51
  text.
Functional Groups
• Influence the chemical
  characteristic of the
  molecule that they are
  attached to.
• Common functional
  groups: Hydroxyl,
  Carboxyl, Amino and
  Phosphate pg. 52 text.
Large Carbon Molecules
• Many large carbon
  molecules are built
  from smaller
  components called
  monomers
• Monomers bond to
  each other to form
  polymers via
  condensation
  reactions. pg. 53
Structure of ATP –Energy
        Molecule
Polymers and Macromolecules
                       Mini-Quiz
1.   All compounds can be classified into two categories
     _________ and __________
2.   _______compounds are made of carbon atoms and
     _________ compounds do not contain carbon.
3.   Carbon atoms are able to form _____ covalent bonds.
4.   _________ is the functional group that causes a
     molecule to classified as polar.
5.   __________ is the functional group that causes a
     molecule to be classified as an acid.
6.   Polymers are large molecules that can be formed from
     smaller molecules called _________ by a _________
     chemical reaction.
7.   The opposite chemical reaction which breaks apart
     polymers is called ______________.
8.   The molecule _________ is hydrolyzed by a reaction
     to produce energy.
Molecules of Life
• Four main classes
  of compounds are
  essential to life
  processes of all
  living things.
• Carbohydrates
• Lipids
• Proteins
• Nucleic acids
Carbohydrates
• Organic compounds
  composed of carbon,
  hydrogen and oxygen
• The chemical ratio is:
• 1 carbon: 2 hydrogen:
  1 oxygen
• Can serve as a source
  of energy and can be
  used as structural
  materials.
• Can be in the form of
  monosaccharides,
  disaccharides, or
  polysaccharides.
Carbohydrates
•   A monomer unit of a
    carbohydrate is called a
    monosaccharide. The ratio
    for the atoms is 1:2:1
•   The most common
    monosaccharides are:
•   Glucose: main source of
    energy for cells
•   Fructose: found in fruits,
    very sweet
•   Galactose: found in milk
•   All are isomers – They have
    the same chemical formula
    but they are different in
    structure. pg. 55 fig 3.6
•   Question: What are the
    monomer units of
    carbohydrates?
Carbohydrates
•   Disaccharides – formed by
    two monomer sugar units
    bonding together by a
    condensation reaction.
•   Ex. Glucose and Fructose
    combine to form Sucrose.
•   Polysaccharides –
    composed of three or more
    monosaccharides.
•   Glucose is stored in the
    polysaccharide form,
    glycogen in animals.
•   Glucose is stored in the liver
    and muscles as glycogen for
    energy.
•   Question: How is glucose
    stored in liver and muscle ?
Carbohydrates
• Plants store glucose
  molecules in the form of
  the polysaccharide –
  Starch / utilized for energy.
• Plants also make a
  polysaccharide called
  cellulose. Cellulose
  provides the plant with
  strength and rigidity –
  makes up about 50% of
  wood.
• Question: What are two
  forms of glucose found in
  plants?
Molecules of Life Quiz
1.   The four main classes of compounds essential to all living things
     are
     A.____________
     B.____________
     C.____________
     D.____________

2.  The ratio of organic compounds containing carbon, hydrogen and
    oxygen is ____ : ____ : ____
3.  Organic compounds can serve as a source of _____ and can be
    used as ____________.
4.  A monomer unit of a carbohydrate is called a _________
5.  The monosaccharide found in milk is called _________.
6.  The monosaccharide which is the main energy source for cells is
    ___________.
7.  Disaccharides are formed by ________________.
8.  Polysaccharides are composed of __________________.
9.  Plants store glucose in the form of ______ and _________.
10. Starch is used for _______ by plants.
Proteins
• Composed of monomer
  units called amino
  acids. pg. 56 fig b.
• Ex. Skin, muscle, hair,
  enzymes etc. are
  composed of proteins.
• Amino acids link
  together by peptide
  bonds to form proteins.
• Enzymes are protein
  molecules that are
  biological catalysts –
  they are able to
  increase the rate of
  reactions.
Amino acids
• 20 different amino
  acids. All share a basic
  structure.
• Contains central carbon
  covalently bonded to
  other atoms or
  functional groups.
• The main difference in
  amino acids are the R
  groups.
• Question: What are the
  monomer units of
  proteins?
Amino acids
• Amino acids join via a
  condensation reaction
  to form peptide bonds
• Amino acids also form
  long chains called
  polypeptides
• Proteins are made of
  one or more peptide
  bonds
• Longer polypeptides
  can be of different
  shapes due to
  hydrogen bonding
  interactions. - heat and
  acidity can affect
  proteins.
ENZYMES
• Protein or RNA
  molecules that act as
  biological catalysts.
• Enzymes have specific
  substrate molecules
  that fit within the active
  site of the enzyme.
• Enzymes lower the
  activation energy of a
  chemical reaction.
• Enzyme is unchanged
  and can be used many
  times – Temperature
  and pH can causes
  changes in the enzyme
  and substrate pg. 57
Polymers and Macromolecules
                  Mini-Quiz
1.   All compounds can be classified into two categories
     _________ and __________
2.   _______compounds are made of carbon atoms and
     _________ compounds do not contain carbon.
3.   Carbon atoms are able to form _____ covalent bonds.
4.   _________ is the functional group that causes a
     molecule to classified as polar.
5.   __________ is the functional group that causes a
     molecule to be classified as an acid.
6.   Polymers are large molecules that can be formed from
     smaller molecules called _________ by a _________
     chemical reaction.
7.   The opposite chemical reaction which breaks apart
     polymers is called ______________.
8.   The molecule _________ is hydrolyzed by a reaction
     to produce energy.
Biology 10.30.12
                       Mr. Hunter

• Objectives:
• SWBAT
• Analyze and compare the structure and characteristics of
  various classes of lipids via active cornell notes.
• Read and answer questions from article, Why Some
  Fats Are Worse Than Others
• (*Common Core Technical Reading Standards*)
• Bell Ringer: If a substance does not dissolve in water, is
  it (polar / nonpolar)?
Lipids
• Large nonpolar organic molecules. They
  don’t dissolve in water.
• They include:
• Triglycerides
• Phospholipids
• Steroids
• Waxes
• Pigments

• Question: What are the five categories of
  lipids?
Lipids
• Lipids have a higher ratio of carbon
  and hydrogen atoms to oxygen atoms.
• Because of this higher ratio they are
  able to store more energy per gram
  than carbohydrates.

• Question: Why are lipids able to store
  more energy than carbohydrates?
Lipids
• Fatty acids:
  unbranched carbon
  chains that make up
  most lipids.
• The carboxyl end is
  polar- hydrophilic and
  the other end is
  nonpolar-hydrophobic

• Question: What is the
  difference between
  saturated and
  unsaturated fatty
  acids?
Triglycerides
• Three classes of lipids
  contain fatty acids:
  triglycerides,
  phospholipids and
  waxes.
• Triglyceride: three fatty
  acids joined to glycerol
• Can be saturated – high
  melting point and solid
  at room temp. Found in
  butter and fats.
• Unsaturated- soft or
  liquid at room
  temperature – found in
  plant seeds.
Phospholipids
• Two or three fatty acids
  attached to a molecule
  of glycerol.
• Phosphate group
  attached to third carbon
  of glycerol.
• Cell membrane is made
  up of two layers of
  phospholipids called
  the lipid bilayer.

• Question: What portion
  of a phospholipid is
  polar or hydrophilic?
Waxes and Steroids
          • Wax: Structural lipid
            made of long fatty acid
            and alcohol chains. They
            are waterproof and
            provide a protective outer
            coating on surfaces.

             Steroids: Steroid are
            made of 4 fused carbon
            rings and various
            functional groups.
            Cholesterol is located in
            the cell membrane and is
            needed by nerve cells to
            function properly.
Polymers and Macromolecules
                  Mini-Quiz
1.   All compounds can be classified into two categories
     _________ and __________
2.   _______compounds are made of carbon atoms and
     _________ compounds do not contain carbon.
3.   Carbon atoms are able to form _____ covalent bonds.
4.   _________ is the functional group that causes a
     molecule to classified as polar.
5.   __________ is the functional group that causes a
     molecule to be classified as an acid.
6.   Polymers are large molecules that can be formed from
     smaller molecules called _________ by a _________
     chemical reaction.
7.   The opposite chemical reaction which breaks apart
     polymers is called ______________.
8.   The molecule _________ is hydrolyzed by a reaction
     to produce energy.
Carbohydrates
                    Mini-Quiz
1.   Carbohydrates can be classified as organic compounds
     containing the elements _______, ______ and _______
2.   The chemical ratio of the elements is ____: ____:____
3.   A polysaccharide is composed of _______ or more_______
4.   The monomer unit of a carbohydrate is called a _______
5.   _________, ________ and ______ are common
     monosaccharides which are all ________. They have the same
     chemical formula but different chemical structures.
6.   ________ and _________combine by a condensation reaction to
     form the disaccharide sucrose.
7.   ________ is a polysaccharide made of glucose monomers and
     is stored in liver and muscle cells.
8.   ________ and ________ are polysaccharides found in plant
     cells used for energy and structural support.
Protein Experiment – Bell Ringer
•    The pH scale measures the
     acidity of a solution. The
     scale ranges from 0 to 14.
•    0  6 is acidic,7 is neutral
     and 8 14 is basic. pg. 44
     fig. 2-14
1.   What are the independent
     and dependent variables?
2.   For each of the proteins,
     trypsin and pepsin, what is
     the best pH value in which
     the reaction rates are the
     highest?
Assignment
• Pg. 60 # 8-10- Critical Thinking
• Cornell Format
• Due @ end of class!
Assignment
•   Section 2 Review pg. 60 # 1-4
•   Pg. 62 # 5-14
•   Cornell Note Format
•   Due @ end of class!
Assignment

• Pg. 55 Vocabulary due @ end of class!
  Pg. 58 Treating and Preventing Diabetes
  Questions: # 1-3 : due @ end of class.
• All in Cornell Format.

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Biochemistry Chapter 3 Summary

  • 1. Biochemistry Chapter 3 Mr. Hunter Biology Kennedy High School 10/18/2011
  • 2. Biology Mr. Hunter 10/23/2012 • Objectives • SWBAT • Analyze the structure of carbohydrates, proteins, lipids and nucleic acids. • Identify polymer and monomer units and their construction process
  • 3. Bell Ringer 03/19/2013 - Biology 1. What are the independent and dependent variables? 2. On which axis is the dependent variable located on? 3. On which axis is the independent variable on? 4. At what time is the temperature approximately 80 degrees?
  • 4. Carbon Compounds • All compounds can be classified into two categories: Organic and Inorganic • Most matter in living organisms that is not water is made of organic compounds. • Organic compounds are made of carbon atoms. • Inorganic compounds do not contain carbon atoms.
  • 5. Carbon Compounds • Carbon atoms are able to form 4 covalent bonds with other atoms of different elements. • Carbon can bond in different ways to produce molecules of different shapes. pg. 51 text.
  • 6. Functional Groups • Influence the chemical characteristic of the molecule that they are attached to. • Common functional groups: Hydroxyl, Carboxyl, Amino and Phosphate pg. 52 text.
  • 7. Large Carbon Molecules • Many large carbon molecules are built from smaller components called monomers • Monomers bond to each other to form polymers via condensation reactions. pg. 53
  • 8. Structure of ATP –Energy Molecule
  • 9. Polymers and Macromolecules Mini-Quiz 1. All compounds can be classified into two categories _________ and __________ 2. _______compounds are made of carbon atoms and _________ compounds do not contain carbon. 3. Carbon atoms are able to form _____ covalent bonds. 4. _________ is the functional group that causes a molecule to classified as polar. 5. __________ is the functional group that causes a molecule to be classified as an acid. 6. Polymers are large molecules that can be formed from smaller molecules called _________ by a _________ chemical reaction. 7. The opposite chemical reaction which breaks apart polymers is called ______________. 8. The molecule _________ is hydrolyzed by a reaction to produce energy.
  • 10. Molecules of Life • Four main classes of compounds are essential to life processes of all living things. • Carbohydrates • Lipids • Proteins • Nucleic acids
  • 11. Carbohydrates • Organic compounds composed of carbon, hydrogen and oxygen • The chemical ratio is: • 1 carbon: 2 hydrogen: 1 oxygen • Can serve as a source of energy and can be used as structural materials. • Can be in the form of monosaccharides, disaccharides, or polysaccharides.
  • 12. Carbohydrates • A monomer unit of a carbohydrate is called a monosaccharide. The ratio for the atoms is 1:2:1 • The most common monosaccharides are: • Glucose: main source of energy for cells • Fructose: found in fruits, very sweet • Galactose: found in milk • All are isomers – They have the same chemical formula but they are different in structure. pg. 55 fig 3.6 • Question: What are the monomer units of carbohydrates?
  • 13. Carbohydrates • Disaccharides – formed by two monomer sugar units bonding together by a condensation reaction. • Ex. Glucose and Fructose combine to form Sucrose. • Polysaccharides – composed of three or more monosaccharides. • Glucose is stored in the polysaccharide form, glycogen in animals. • Glucose is stored in the liver and muscles as glycogen for energy. • Question: How is glucose stored in liver and muscle ?
  • 14. Carbohydrates • Plants store glucose molecules in the form of the polysaccharide – Starch / utilized for energy. • Plants also make a polysaccharide called cellulose. Cellulose provides the plant with strength and rigidity – makes up about 50% of wood. • Question: What are two forms of glucose found in plants?
  • 15. Molecules of Life Quiz 1. The four main classes of compounds essential to all living things are A.____________ B.____________ C.____________ D.____________ 2. The ratio of organic compounds containing carbon, hydrogen and oxygen is ____ : ____ : ____ 3. Organic compounds can serve as a source of _____ and can be used as ____________. 4. A monomer unit of a carbohydrate is called a _________ 5. The monosaccharide found in milk is called _________. 6. The monosaccharide which is the main energy source for cells is ___________. 7. Disaccharides are formed by ________________. 8. Polysaccharides are composed of __________________. 9. Plants store glucose in the form of ______ and _________. 10. Starch is used for _______ by plants.
  • 16. Proteins • Composed of monomer units called amino acids. pg. 56 fig b. • Ex. Skin, muscle, hair, enzymes etc. are composed of proteins. • Amino acids link together by peptide bonds to form proteins. • Enzymes are protein molecules that are biological catalysts – they are able to increase the rate of reactions.
  • 17. Amino acids • 20 different amino acids. All share a basic structure. • Contains central carbon covalently bonded to other atoms or functional groups. • The main difference in amino acids are the R groups. • Question: What are the monomer units of proteins?
  • 18. Amino acids • Amino acids join via a condensation reaction to form peptide bonds • Amino acids also form long chains called polypeptides • Proteins are made of one or more peptide bonds • Longer polypeptides can be of different shapes due to hydrogen bonding interactions. - heat and acidity can affect proteins.
  • 19. ENZYMES • Protein or RNA molecules that act as biological catalysts. • Enzymes have specific substrate molecules that fit within the active site of the enzyme. • Enzymes lower the activation energy of a chemical reaction. • Enzyme is unchanged and can be used many times – Temperature and pH can causes changes in the enzyme and substrate pg. 57
  • 20. Polymers and Macromolecules Mini-Quiz 1. All compounds can be classified into two categories _________ and __________ 2. _______compounds are made of carbon atoms and _________ compounds do not contain carbon. 3. Carbon atoms are able to form _____ covalent bonds. 4. _________ is the functional group that causes a molecule to classified as polar. 5. __________ is the functional group that causes a molecule to be classified as an acid. 6. Polymers are large molecules that can be formed from smaller molecules called _________ by a _________ chemical reaction. 7. The opposite chemical reaction which breaks apart polymers is called ______________. 8. The molecule _________ is hydrolyzed by a reaction to produce energy.
  • 21. Biology 10.30.12 Mr. Hunter • Objectives: • SWBAT • Analyze and compare the structure and characteristics of various classes of lipids via active cornell notes. • Read and answer questions from article, Why Some Fats Are Worse Than Others • (*Common Core Technical Reading Standards*) • Bell Ringer: If a substance does not dissolve in water, is it (polar / nonpolar)?
  • 22. Lipids • Large nonpolar organic molecules. They don’t dissolve in water. • They include: • Triglycerides • Phospholipids • Steroids • Waxes • Pigments • Question: What are the five categories of lipids?
  • 23. Lipids • Lipids have a higher ratio of carbon and hydrogen atoms to oxygen atoms. • Because of this higher ratio they are able to store more energy per gram than carbohydrates. • Question: Why are lipids able to store more energy than carbohydrates?
  • 24. Lipids • Fatty acids: unbranched carbon chains that make up most lipids. • The carboxyl end is polar- hydrophilic and the other end is nonpolar-hydrophobic • Question: What is the difference between saturated and unsaturated fatty acids?
  • 25. Triglycerides • Three classes of lipids contain fatty acids: triglycerides, phospholipids and waxes. • Triglyceride: three fatty acids joined to glycerol • Can be saturated – high melting point and solid at room temp. Found in butter and fats. • Unsaturated- soft or liquid at room temperature – found in plant seeds.
  • 26. Phospholipids • Two or three fatty acids attached to a molecule of glycerol. • Phosphate group attached to third carbon of glycerol. • Cell membrane is made up of two layers of phospholipids called the lipid bilayer. • Question: What portion of a phospholipid is polar or hydrophilic?
  • 27. Waxes and Steroids • Wax: Structural lipid made of long fatty acid and alcohol chains. They are waterproof and provide a protective outer coating on surfaces. Steroids: Steroid are made of 4 fused carbon rings and various functional groups. Cholesterol is located in the cell membrane and is needed by nerve cells to function properly.
  • 28. Polymers and Macromolecules Mini-Quiz 1. All compounds can be classified into two categories _________ and __________ 2. _______compounds are made of carbon atoms and _________ compounds do not contain carbon. 3. Carbon atoms are able to form _____ covalent bonds. 4. _________ is the functional group that causes a molecule to classified as polar. 5. __________ is the functional group that causes a molecule to be classified as an acid. 6. Polymers are large molecules that can be formed from smaller molecules called _________ by a _________ chemical reaction. 7. The opposite chemical reaction which breaks apart polymers is called ______________. 8. The molecule _________ is hydrolyzed by a reaction to produce energy.
  • 29. Carbohydrates Mini-Quiz 1. Carbohydrates can be classified as organic compounds containing the elements _______, ______ and _______ 2. The chemical ratio of the elements is ____: ____:____ 3. A polysaccharide is composed of _______ or more_______ 4. The monomer unit of a carbohydrate is called a _______ 5. _________, ________ and ______ are common monosaccharides which are all ________. They have the same chemical formula but different chemical structures. 6. ________ and _________combine by a condensation reaction to form the disaccharide sucrose. 7. ________ is a polysaccharide made of glucose monomers and is stored in liver and muscle cells. 8. ________ and ________ are polysaccharides found in plant cells used for energy and structural support.
  • 30. Protein Experiment – Bell Ringer • The pH scale measures the acidity of a solution. The scale ranges from 0 to 14. • 0  6 is acidic,7 is neutral and 8 14 is basic. pg. 44 fig. 2-14 1. What are the independent and dependent variables? 2. For each of the proteins, trypsin and pepsin, what is the best pH value in which the reaction rates are the highest?
  • 31. Assignment • Pg. 60 # 8-10- Critical Thinking • Cornell Format • Due @ end of class!
  • 32. Assignment • Section 2 Review pg. 60 # 1-4 • Pg. 62 # 5-14 • Cornell Note Format • Due @ end of class!
  • 33. Assignment • Pg. 55 Vocabulary due @ end of class! Pg. 58 Treating and Preventing Diabetes Questions: # 1-3 : due @ end of class. • All in Cornell Format.