This document summarizes a keynote address given by Mario Bunge on systemism. It begins by noting that small problems can be addressed within individual disciplines, while larger, systemic problems require multidisciplinary collaboration. It then discusses how systemism provides an alternative to atomism and holism by combining top-down and bottom-up analysis. Systemism views the world as composed of interconnected systems and was first proposed in the 18th century. While little known in philosophy, scientists have generally practiced systemism. The document defines a system as having composition, environment, structure, and mechanisms. It argues systemism is a key part of the philosophical framework underpinning scientific research.