This document discusses advancements in gene therapy techniques for treating blindness. It describes the first successful gene therapy treatment for blindness in the UK in 2007. The patient, Robert Johnson, was born blind due to a mutation in the RPE65 gene. Surgeons injected a replacement gene into his retina using an incredibly precise procedure. Initial results found Johnson could see outlines, though not clearly at night. The document outlines the science behind the treatment and genetic cause of the patient's blindness. It provides context on the cutting-edge nature of this gene therapy technique at the time and hopes it could eventually help more complex organs.
Every day, there is something new that may or may not have an impact on our daily practice. In this talk , we want to highlight some of these new developments
Bible Matrix 5_59_②_UK’s successful gene transfer to several congenital blindswycha
Bible Matrix 5_59_②_UK’s successful gene transfer to several congenital blinds
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 7. Jesus healed many blind men and a deaf-mutism(deaf & dumb), but how?
Verse 1. Current & future cutting-edge science and technology to repair blindness
1-3. ② UK’s successful gene transfer to several congenital blinds
1-3-2. Victory of 2008, 18-years-old congenital blind man opened eyes
1-3-3. Future therapy & treatment
https://www.youtube.com/watch?v=UM2OkDWBOXc
Bible Matrix 5_60_Bioengineering and Bionics–Retinal display, bionic eye and ...wycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 7. Jesus healed many blind men and a deaf-mutism(deaf & dumb), but how?
Verse 1. Current & future cutting-edge science and technology to repair blindness
1-4. Bioengineering/Bionics–Retinal display, bionic eye and electronic eye
1-4-1. University of Washington developed a Virtual Retinal Display
1-4-2. USA/German–Bionic eye will let the acquired blind see
1-4-3. University of Illinois developed a hemispherical electronic eye
https://www.youtube.com/watch?v=h8h-zyVjkc0
Bible Matrix 5_68_②_Current & future cutting-edge science and technology to c...wycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 8. Jesus cleaned many leprosy and healed a shriveled hand & cut off right ear, but how?
Verse 3. ② Current & future cutting-edge science and technology to clean leprosy
3-2. Bionics–artificial skin & bionic ear
https://www.youtube.com/watch?v=sQ79eoXcQ3A
Bible Matrix 5_43_Region of Interest(ROI), Mental Model and Mind Patternwycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 5. Jesus drove demon(s) out of demon(s)-possessed men/women with the word
Verse 1. Current & future brain/neuro science, psychiatry, brain/mental model
1-3. Region of Interest(ROI), Mental Model & Mind Pattern
https://www.youtube.com/watch?v=1mlRwkEMYVU
Bible Matrix 5_27_Current & future alternative medicinewycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 2. Current and future medical science & medical technique
Verse 3. Current & future alternative & regenerative medicine
3-1. Alternative medicine
https://www.youtube.com/watch?v=OQxpfCbHFAc
Every day, there is something new that may or may not have an impact on our daily practice. In this talk , we want to highlight some of these new developments
Bible Matrix 5_59_②_UK’s successful gene transfer to several congenital blindswycha
Bible Matrix 5_59_②_UK’s successful gene transfer to several congenital blinds
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 7. Jesus healed many blind men and a deaf-mutism(deaf & dumb), but how?
Verse 1. Current & future cutting-edge science and technology to repair blindness
1-3. ② UK’s successful gene transfer to several congenital blinds
1-3-2. Victory of 2008, 18-years-old congenital blind man opened eyes
1-3-3. Future therapy & treatment
https://www.youtube.com/watch?v=UM2OkDWBOXc
Bible Matrix 5_60_Bioengineering and Bionics–Retinal display, bionic eye and ...wycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 7. Jesus healed many blind men and a deaf-mutism(deaf & dumb), but how?
Verse 1. Current & future cutting-edge science and technology to repair blindness
1-4. Bioengineering/Bionics–Retinal display, bionic eye and electronic eye
1-4-1. University of Washington developed a Virtual Retinal Display
1-4-2. USA/German–Bionic eye will let the acquired blind see
1-4-3. University of Illinois developed a hemispherical electronic eye
https://www.youtube.com/watch?v=h8h-zyVjkc0
Bible Matrix 5_68_②_Current & future cutting-edge science and technology to c...wycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 8. Jesus cleaned many leprosy and healed a shriveled hand & cut off right ear, but how?
Verse 3. ② Current & future cutting-edge science and technology to clean leprosy
3-2. Bionics–artificial skin & bionic ear
https://www.youtube.com/watch?v=sQ79eoXcQ3A
Bible Matrix 5_43_Region of Interest(ROI), Mental Model and Mind Patternwycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 5. Jesus drove demon(s) out of demon(s)-possessed men/women with the word
Verse 1. Current & future brain/neuro science, psychiatry, brain/mental model
1-3. Region of Interest(ROI), Mental Model & Mind Pattern
https://www.youtube.com/watch?v=1mlRwkEMYVU
Bible Matrix 5_27_Current & future alternative medicinewycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 2. Current and future medical science & medical technique
Verse 3. Current & future alternative & regenerative medicine
3-1. Alternative medicine
https://www.youtube.com/watch?v=OQxpfCbHFAc
Biology, genetics, nanotechnology, neuroscience, materials science, biotech, ...Brian Russell
Over the past two years I've done a lot of interesting research which I've decided to aggregate. My research pertains to the following: Biology, Genetics, Nanotechnology, Neuroscience, Materials Science, Biotechnology, Chemical Engineering, All Things 3-D, Super Computing, Quantum Physics, Energy, Design, & Sustainability.
Bible Matrix 5_28_Current & future regenerative medicine to raise the deadwycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 2. Current and future medical science & medical technique
Verse 3. Current & future alternative & regenerative medicine
3-2. Regenerative medicine to raise the dead - stimulated by light as energy and wave
Bible Matrix 5_40_Bioimaging technology–Brain waves and EEG: How to detect an...wycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 5. Jesus drove demon(s) out of demon(s)-possessed men/women with the word
Verse 1. Current & future brain/neuro science, psychiatry, brain/mental model
1-2. Bioimaging technology–Brain waves and EEG: How to detect and drive demon(s)?
https://www.youtube.com/watch?v=5Ol0vZt68BQ
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 5. Jesus drove demon(s) out of demon(s)-possessed men/women with the word
Verse 1. Current & future brain/neuro science, psychiatry, brain/mental model
https://www.youtube.com/watch?v=-9s777_anJg
Joseph B. Genetic Engineering to cure disorders and diseases, period 6.
Ryan Lacker, (same topic), period 8.
16 slides. If the second video on slide 7 doesn't work, please go to this link:
http://www.youtube.com/watch?v=Z0SQKXXXI6Q
From the Stem Cell workshop at the Bio-Link Summer Fellows Forum 2011
presenters: Edie Kaeuper, Carin Zimmerman, Golnar Afshar, Samantha Croft, & Bill Woodruff
Bible Matrix 5_39_Human brain strategy of USA and EUwycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 5. Jesus drove demon(s) out of demon(s)-possessed men/women with the word
Verse 1. Current & future brain/neuro science, psychiatry, brain/mental model
1-1. Human brain strategy of USA & EU
https://www.youtube.com/watch?v=Mfcsp4vHbKM
Concussions, TBI, Reading, Balance, Car-Sickness, Attention, Visual Fatigue Problems Vision Therapy 101 for the Primary Care Practitioner By Stan Appelbaum, OD
Bible Matrix 5_31_Current & future IoB, Jesus might be armed with IoB_③wycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 2. Current and future medical science & medical technique
Verse 4. Current & future IoB, Jesus might be armed with IoB
4-3. Body/Skin Communications, and Power & Data Transfer thru Human Body/Skin
https://www.youtube.com/watch?v=zGz8r2exPw4
Gene Wiki and Mark2Cure update for BD2KBenjamin Good
An introduction to the Gene Wiki project with an emphasis on the use of the new WikiData project. Also describes mark2cure, a citizen science initiative oriented on biomedical text mining.
Bible Matrix ⑦_36_Dragon is ancient serpent, devil, Satan, who made Eve give...wycha
Youtube - https://www.youtube.com/watch?v=O9OEFI87m2s
Bible Matrix ⑦: Historical & Scientific Views on Daniel and Revelation
Part 1. <Daniel>
Chapter 7 of <Daniel>: Daniel's Dream of Four Beasts
4. Comparison between kingdoms in Daniel 7:21 & 25 and dragon with beasts in Revelation 13:4~7
4-7. What and who is the dragon, ancient serpent, devil, or Satan?
4-7-1. Dragon is ancient serpent, devil, Satan, who made Eve give birth to child
BBible Matrix ⑦_30_Revelation 12:7~9, Great dragon(Satan) will be hurled down...wycha
Youtube - https://www.youtube.com/watch?v=OGNFvlzHVr0
Bible Matrix ⑦: Historical & Scientific Views on Daniel and Revelation
Chapter 7 of <Daniel>: Daniel's Dream of Four Beasts
Part 1. Daniel
4. Comparison between Roman Catholic in Daniel 7:21 & 25 and dragon with beasts in Revelation 13:4~7
4-1. Revelation 12:7~9 - Great dragon(Satan or unrighteous God) will be hurled down to the earth(c.AD 10,733~)
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Over the past two years I've done a lot of interesting research which I've decided to aggregate. My research pertains to the following: Biology, Genetics, Nanotechnology, Neuroscience, Materials Science, Biotechnology, Chemical Engineering, All Things 3-D, Super Computing, Quantum Physics, Energy, Design, & Sustainability.
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Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
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Chapter 5. Jesus drove demon(s) out of demon(s)-possessed men/women with the word
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1-2. Bioimaging technology–Brain waves and EEG: How to detect and drive demon(s)?
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Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
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https://www.youtube.com/watch?v=-9s777_anJg
Joseph B. Genetic Engineering to cure disorders and diseases, period 6.
Ryan Lacker, (same topic), period 8.
16 slides. If the second video on slide 7 doesn't work, please go to this link:
http://www.youtube.com/watch?v=Z0SQKXXXI6Q
From the Stem Cell workshop at the Bio-Link Summer Fellows Forum 2011
presenters: Edie Kaeuper, Carin Zimmerman, Golnar Afshar, Samantha Croft, & Bill Woodruff
Bible Matrix 5_39_Human brain strategy of USA and EUwycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
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Verse 1. Current & future brain/neuro science, psychiatry, brain/mental model
1-1. Human brain strategy of USA & EU
https://www.youtube.com/watch?v=Mfcsp4vHbKM
Concussions, TBI, Reading, Balance, Car-Sickness, Attention, Visual Fatigue Problems Vision Therapy 101 for the Primary Care Practitioner By Stan Appelbaum, OD
Bible Matrix 5_31_Current & future IoB, Jesus might be armed with IoB_③wycha
Bible Matrix ⑤: Science & Technology of Jesus Christ with the Holy Spirit
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 2. Current and future medical science & medical technique
Verse 4. Current & future IoB, Jesus might be armed with IoB
4-3. Body/Skin Communications, and Power & Data Transfer thru Human Body/Skin
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Bible Matrix ⑦_36_Dragon is ancient serpent, devil, Satan, who made Eve give...wycha
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Chapter 7 of <Daniel>: Daniel's Dream of Four Beasts
4. Comparison between kingdoms in Daniel 7:21 & 25 and dragon with beasts in Revelation 13:4~7
4-7. What and who is the dragon, ancient serpent, devil, or Satan?
4-7-1. Dragon is ancient serpent, devil, Satan, who made Eve give birth to child
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4. Comparison between Roman Catholic in Daniel 7:21 & 25 and dragon with beasts in Revelation 13:4~7
4-1. Revelation 12:7~9 - Great dragon(Satan or unrighteous God) will be hurled down to the earth(c.AD 10,733~)
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Chapter 7 of <Daniel>: Daniel's Dream of Four Beasts
1-3. Daniel 7:6 – Third kingdom – Leopard: Greek(Hella) Empire(BC 514~BC 146 or BC 30)
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Bible Matrix ⑦_3_Daniel 2:39, The second kingdom – Silver: Persian Empire(BC ...wycha
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Bible Matrix ⑦: Historical & Scientific Views on <Daniel> and <Revelation>
Part 1. Daniel
Chapter 2 of Daniel: The first ~ the fourth Kingdom, and God of heaven will set up a kingdom
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차원용의 미래_11_생체인터넷/생체에너지(Internet of Biosignal/Bioenergy)wycha
차원용의 미래_11_생체인터넷/생체에너지(Internet of Biosignal/Bioenergy), Background & Definition, Internet of Biosignal, Internet of Biometrics, Evolution of IoB, WCs(Put on or Have on), WCs(Robes or Clothes), WCs(Attachable), Point of Care(PoC), Microimplants, Eatable or Digestible, Smart pill, Internet of Bioenergy, Movement energy, Temperature energy, Heat energy, Conductive body, Mineral ions
생체인터넷/생체에너지(Internet of Biosignal/Bioenergy)
I. Background - Definition
II. Evolution of IoB
III. WCs(Put on or Have on)
IV. WCs(Robes or Clothes)
V. WCs(Attachable)
VI. Point of Care(PoC)
VII. Microimplants
VIII. IoB(Internet of Bioenergy)
VIV. Other Challenges
X. Conclusion
Youtube:
(1) https://www.youtube.com/watch?v=zJBAD1zxTCk
(2) https://www.youtube.com/watch?v=OfzBfqKVs_E
(3) https://www.youtube.com/watch?v=4qkwJr4QEYU
(4) https://www.youtube.com/watch?v=s0tnbvATtXQ
(5) https://www.youtube.com/watch?v=L4nONmkHpVI
(6) https://www.youtube.com/watch?v=qm6goo18i5s
(7) https://www.youtube.com/watch?v=XfZD5yRnVT0
Bible Matrix 6_59_Mayan calendar not ended on 21 Dec 2012 but lasting until 1...wycha
Youtube – https://www.youtube.com/watch?v=fL095E4gm0M
Bible Matrix ⑥: Predicting the Second Coming of Jesus(c.AD 10,740~)
Part 2. This Generation: Predicting the Second Coming of Jesus(c.AD 10,740)
Chapter 1. Predicting Signs and Times of 12 constellations as This Generation, and Mayan calendar not ended on 21 Dec 2012 but lasting until 12,900
Verse 6. Mayan calendar not ended on 21 Dec 2012 but lasting until 12,900
Bible Matrix 6_54_Sign of Capricorn(AD 4,260~6,419), New kingdom with its nat...wycha
Youtube – https://www.youtube.com/watch?v=FoTudero7d0
Bible Matrix ⑥: Predicting the Second Coming of Jesus(c.AD 10,740~)
Part 2. This Generation: Predicting the Second Coming of Jesus(c.AD 10,740)
Chapter 1. Predicting Signs and Times of 12 constellations as This Generation, and Mayan calendar not ended on 21 Dec 2012 but lasting until 12,900
5. Sign of Capricorn(AD 4,260~6,419)~Virgo(AD 12,900~)
Verse 5-1. Sign of Capricorn(AD 4,260~6,419) – New kingdom with its nations on and in the sea
Bible Matrix 6_52_At Aquarius, the heat/magma/water under the earth, the new ...wycha
Youtube – https://www.youtube.com/watch?v=pvZNRrQ-Xc0
Bible Matrix ⑥: Predicting the Second Coming of Jesus(c.AD 10,740~)
Part 2. This Generation: Predicting the Second Coming of Jesus(c.AD 10,740)
Chapter 1. Predicting Signs and Times of 12 constellations as This Generation, and Mayan calendar not ended on 21 Dec 2012 but lasting until 12,900
4. Sign of Aquarius(AD 2,100~4,259) – New kingdoms will be appeared on the earth, under the earth, and in the sky
Verse 4-3. The heat/magma/water under the earth, the new kingdom with its nations in Abyss, biomimetic robots mixed locust with scorpion
승객을 위한 자율주행차의 미래 _
I. Federal Automated Vehicles Policy Guideline
II. Status of Self-Driving Test
III. Disengagement Report
IV. Technology Competition
V. Conclusion
Youtube:
(1) https://www.youtube.com/watch?v=YJZaUVsxpMU
(2) https://www.youtube.com/watch?v=B9SW4i2nHDY
(3) https://www.youtube.com/watch?v=XUYhTtCN8C8
(4) https://www.youtube.com/watch?v=eP4Q0kz9MT4
(5) https://www.youtube.com/watch?v=QMdIXCkg6Nk
(6) https://www.youtube.com/watch?v=Gsub9iIAQ80
(7) https://www.youtube.com/watch?v=HOoQ4S3bXuU
Apple이 3년내 출시할 제품/서비스
I. Hurdles of Current AR/VR
II. Cloud->Edge AI(As Is) : A14 Bionic Chip(’20)
III. Neural Engine(‘17) - A14 BC(‘20)
IV. Apple의 3D Avatar/Model(To Be)
V. 3D UI/UX의 AR/VR for Mac/TV(To Be)
VI. 3D UI/UX의 AR/VR for Car/EV/AV(To Be)
VII. 3D GUI/GUX의 OS/App(To Be)
VIII. 3D GUI/GUX의 브라우저(Safari)(To Be)
VIV. Cloud - Edge Services(To Be)
X. Conclusion
Youtube:
(10) https://www.youtube.com/watch?v=ZoG6nsAXSHo
(9) https://www.youtube.com/watch?v=TurIbiab0hM
(8) https://www.youtube.com/watch?v=3TTYivKHyZc
(7) https://www.youtube.com/watch?v=A_BSv2DQDfo
(6) https://www.youtube.com/watch?v=gU_PG3o2ym8
(5) https://www.youtube.com/watch?v=mBUpPxCkpJg
(4) https://www.youtube.com/watch?v=GM8QJ-58ub4
(3) https://www.youtube.com/watch?v=sqqU0gtCMYw
(2) https://www.youtube.com/watch?v=jeXLiqG2iNA
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Part I. Those who ascended into heaven; the death of Jesus to visit to Paradise/Hell and ascended; Resurrection and Rapture
Chapter 3. Condition, status, and method of resurrection/rapture, the spiritual body at the Second Coming of Jesus
블록체인의 현재와 미래
I. Edge -> Cloud AI(Old)
II. Cloud AI -> Edge AI(As Is)
III. The 1th~3th Blockchain: 개념/기원/원리/유형/합의 알고리즘
IV. The 4th ~ Blockchain
V. 개인정보보호법 국회통과(‘20.01.09)
VI. The 4th Homomorphic Encryption: 문제와 극복방안
VII. The Hurdles of Blockchain: GDPR 회피, 양자내성암호기술
VIII. Technology Roadmap
VIV. Int’l Standard
X. Conclusion: Cloud <-> Edge Services
Youtube:
(8) https://www.youtube.com/watch?v=5OcBZ2Y5wmQ
(7) https://www.youtube.com/watch?v=vdo0Bh9aK-4
(6) https://www.youtube.com/watch?v=j9osbiVk-M4
(5) https://www.youtube.com/watch?v=j9D4aUFU1jY
(4) https://www.youtube.com/watch?v=LC9PSATYt1A
(3) https://www.youtube.com/watch?v=5R2kBkk_UII
(2) https://www.youtube.com/watch?v=vlLK8CsjJEk
(1) https://www.youtube.com/watch?v=tUblnZwzUfM
Bible Matrix 6_12_ Jesus, transformed into a spiritual body, talked with Mose...wycha
Bible Matrix ⑥: Predicting the Second Coming of Jesus(c.AD 10,740~)
Part I. Those who ascended into heaven; the death of Jesus to visit to Paradise/Hell and ascended; Resurrection and Rapture
Chapter 1. God(Elohim) have spiritual bodies, those who ascended into heaven, Jesus talked with Moses and Elijah, paradise, two witnesses
3. Who are the two witnesses? Moses and Elijah, The same way as Jesus: Death – Resurrection – Transformation - Ascension
3-1. Jesus was transformed or transfigured into a spiritual body and talked with Moses and Elijah on the spaceship
https://www.youtube.com/watch?v=aRsBjZHOqYE
Bible Matrix 6_9_Biblical chariots and white-red-black horses are small space...wycha
Bible Matrix ⑥: Predicting the Second Coming of Jesus(c.AD 10,740~)
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Chapter 1. God(Elohim) have spiritual bodies, those who ascended into heaven, Jesus talked with Moses and Elijah, paradise, two witnesses
2. Those who ascended into heaven, Enoch/Moses/Elijah
2-4. Biblical chariots, white/red/black horses -> small spaceships, manned/unmanned reconnaissance aircraft
https://www.youtube.com/watch?v=EqbksNVZ2e4
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
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redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
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infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
PRESENTATION ABOUT PRINCIPLE OF COSMATIC EVALUATION
Bible Matrix 5_59_①_UK’s successful gene transfer to several congenital blinds
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Bible Matrix 5 : 42 Miracles of Jesus with
the Holy Spirit into Science and Technology
Dr. Won Yong Cha, English Education(BS), MBA, MISE(Ph.D.), Futurist or Futurologist
biblematrix@gmail.com
I am Dr. Won Yong Cha, the author of <Bible
Matrix 5: Science & Technology of Jesus
Christ with the Holy Spirit>, published from
Amazon, USA, via Nobook, 28 Jan 2020;
Korean version, Seoul, Korea, 20 Jan 2015.
https://www.amazon.com/dp/B0849VX88S/
http://www.yes24.com/Product/goods/15896362
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Bible Matrix 5 : 42 Miracles of Jesus with
the Holy Spirit into Science and Technology
Part 2. 42 Miracles of Jesus with the Holy Spirit into Science and Technology
Chapter 7. Jesus healed many blind men and a deaf-mutism(deaf & dumb),
but how?
Verse 1. Current & future cutting-edge science and technology to repair blindness
1-3. ① UK’s successful gene transfer to several congenital blinds
1-3-1. Challenges of 2007, the progress of Gene transplant surgery
In May 2007, the Moorfields Eye Hospital in London tried the world's first gene
therapy for a man named Robert Johnson who was born with blind. Gene therapy
refers to surgery to transplant genes into the eye. Now Johnson, who had genes
inserted into one eye, could see outlines during the day, but little at night.
However, the success or failure of this transplant could only be known for a few
more months. If successful, scientists and doctors expect this gene therapy to
emerge as a breakthrough technology for treating a variety of visual impairments.
The transplant technology was developed in a lab and after clinical trials on
animals, then they tried to Johnson. Johnson was elected out of 12 young patients.
Johnson confessed that he had mixed feelings before surgery. He said, "It's very
difficult to say how I'm feeling. I keep ranging from extreme nervousness to a bit
of excitement.“1)
UK’s successful gene transfer to
several congenital blinds
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Bible Matrix 5 : 42 Miracles of Jesus with
the Holy Spirit into Science and Technology
Lead researcher, Professor Robin Ali has spent 15 years with colleagues for
developing the technique. He said, "I can't help feeling somewhat
apprehensive. We have all been waiting for a very long time.“ His colleague,
James Bainbridge, who carried out the surgery, said there was no guarantee
that it would be a success. However, he said, "It is very encouraging that we
can deliver genes to an extremely fragile site in the eye without
complications.“
LCA - Johnson’s blindness is due to the loss or incomplete function of a gene
called RPE652), which encodes the retinal pigment epithelium(èpəθí:liəm)(RPE, 망막
색 소 상 피 ) and produces a specific protein as 95-kDA. In other words, this
disease is called ‘inherited degeneration of the retina’ or LCA(Leber's
congenital amaurosis)3), which caused by a mutation in the RPE65 gene.
1) BBC - Gene therapy first for poor sight(01 May 2007), http://news.bbc.co.uk/2/hi/health/6609205.stm
2) https://en.wikipedia.org/wiki/RPE65
3) https://en.wikipedia.org/wiki/Leber%27s_congenital_amaurosis
UK’s successful gene transfer to
several congenital blinds
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Bible Matrix 5 : 42 Miracles of Jesus with
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The RPE65 mutation gene disrupts or stops the function of photoreceptor cells
in the retinal pigment epithelium(èpəθí:liəm)(RPE) of the pigment layer which
exists between the retina and sclera behind the eye. These photoreceptor cells
sense lights and send electrical impulses or signals through the optic nerve to
the brain's thalamus(θǽləməs) or visual center. In Johnson's case, the
photoreceptor cells could not detect lights because they were mutated.
What was the level of gene transplant technology in 2007? – The surgery
required incredible precision. One slip and Johnson's retina would have been
torn, then the operation should have failed. However, Robert Maclaren, the
assistant surgeon, was pleased with how things went. He said, "We couldn't
have asked for a better result. In fact if I sat and drew what the perfect result
would have been on a piece of paper - the retina would have looked pretty
much as it would look now."
Professor Andrew George, an expert in molecular immunology(ìmjunάlədʒi) at
Imperial College London, said, "There is a hope that once gene therapy is
developed in the eye, scientists could move on to more complex organs."
UK’s successful gene transfer to
several congenital blinds
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Bible Matrix 5 : 42 Miracles of Jesus with
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Retinal gene therapy, used by researchers, is described as follows:
UK’s successful gene transfer to
several congenital blinds
(망막 유전자 치료)
(망막)
(렌즈, 수정체)
(시신경)
(광수용체 세포들)
(치료 영역인 색소층이 재생)
(바늘로 대체 유전자를 주입)
1) The needle is inserted through the eye and into the retina.
2) The replacement gene is injected between the two layers of cells which make up the retina. It is
a faulty gene in the pigment layer which is preventing the photoreceptor cells from detecting light.
3) Once treated, the cells in the pigment layer are restored and can support the photoreceptor
cells to detect light as normal.
4) The photoreceptor cells can now send nerve impulses to the optic nerve for transmitting to the
brain.