Download to read offline
Uploaded byRuy Pantoja
Beta cell stress en dm2 b
Insulin is essential for regulating blood glucose levels. Type 1 and Type 2 diabetes result from insufficient insulin production or insulin resistance. Researchers are working to develop new therapies that target the molecular pathways involved in insulin production and secretion to restore normal blood glucose control in patients with diabetes.
Beta cell stress en dm2 b
- 1. Interfering with InsulinProduction. Kaufman RJ. N Engl J Med 2011;365:1931-1933.
Editor's Notes
- #2 Figure 2. Interfering with Insulin Production. The production of mature insulin takes place within the beta cell and depends on the cleavage of the preproinsulin and proinsulin molecules. The cleavage site at the junction of the A chain and the C-peptide contains a lysine residue, which is critical for cleavage.