Microsoft Practice has helped many organizations realize their potential by designing and developing custom applications using Microsoft technologies to meet specific needs and optimize operations. The document provides information on various content management systems (CMS) like DotNetNuke, Kentico, Umbraco, and Sitefinity - comparing their features, licensing, and suitability for small and large websites. It also introduces PixelCrayons as a digital consulting firm that offers end-to-end solutions and services related to these CMS and Microsoft technologies.