Backbone.js is a JavaScript library that provides structure to applications by supplying models, collections, and views. It follows an MVC-like pattern, with models representing data, views handling display/interaction logic, and routers managing navigation. Backbone is lightweight and depends on Underscore.js for utility functions. Models manage data and can fetch/save to servers. Collections are ordered sets of models. Views display data and handle events. Routers map URLs to functions. Underscore provides over 100 helper functions for tasks like iteration, filtering, and more.