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This study examined the accumulation of superparamagnetic iron oxide (SPIO) nanoparticles in vulnerable atherosclerotic plaques. In vitro experiments demonstrated that human macrophages actively take up fluorescent-labeled SPIO particles over 24 hours in a time- and concentration-dependent manner. In vivo studies in mice and rabbit models of atherosclerosis found SPIO particles in macrophage-rich areas of plaques, with a strong correlation between iron staining and foam cell density. Cytokine treatment increased SPIO uptake in plaques. The results suggest MRI using SPIO has potential for noninvasively assessing monocyte recruitment in vulnerable plaques.
This study examined the accumulation of superparamagnetic iron oxide (SPIO) nanoparticles in vulnerable atherosclerotic plaques. In vitro experiments demonstrated that human macrophages actively take up fluorescent-labeled SPIO particles over 24 hours in a time- and concentration-dependent manner. In vivo studies in mice and rabbit models of atherosclerosis found SPIO particles in macrophage-rich areas of plaques, with a strong correlation between iron staining and foam cell density. Cytokine treatment increased SPIO uptake in plaques. The results suggest MRI using SPIO has potential for noninvasively assessing monocyte recruitment in vulnerable plaques.
1) Human umbilical cord blood CD34+ enriched cells can engraft and develop in the bone marrow of irradiated NOD/LtSz-scid/scid mice without human growth factor support.
2) The human cells home to the mouse bone marrow and develop into myeloid, lymphoid, erythroid, and CD34+ progenitor populations, indicating development proceeds from primary hematopoietic sites to the periphery.
3) Repopulation of secondary recipients with human cells from primary recipient bone marrow demonstrates the human precursor population maintains substantial proliferative capacity.
Peripheral blood stem cell transplantation (PBSCT) involves collecting stem cells from a patient's bloodstream and later infusing them back into the patient after chemotherapy or radiation therapy. PBSCT has replaced bone marrow as the most common stem cell transplantation procedure. Stem cells are collected from the bloodstream using growth factors alone or with chemotherapy, and the minimum number needed for a safe transplant is 2 million CD34+ cells per kilogram of body weight. PBSCT results in faster recovery time compared to bone marrow transplants due to higher numbers of stem cells and T cells collected.
This document discusses a study evaluating the use of superparamagnetic iron oxide (SPIO) nanoparticles to non-invasively image macrophage infiltration in atherosclerotic plaques via MRI. Researchers injected SPIO into hypercholesterolemic and normal rabbits and found SPIO accumulation correlated with macrophage density in plaques, as observed via histology. SPIO-enhanced MRI identified inflamed plaques in hypercholesterolemic rabbits compared to normal rabbits. The study demonstrates SPIO nanoparticles can be used to non-invasively detect active inflammation in vulnerable atherosclerotic plaques.
Rna sequencing of cardiac cells may elucidate cardiac developmental mechanism...Bennie George
In animal studies, researchers identified multiple cell types in healthy and diseased hearts, and researchers also studied the ‘transcription blueprint’ in detail, where DNA transcribes genetic information into RNA and protein.
https://www.creative-bioarray.com/products/adult-stem-cells-34.htm
The Complete Guide to Know That RNA Sequencing of Cardiac Cells May Elucidate...Bennie George
A research report published in the international magazine Genes & Development, scientists from the Children's Hospital of Philadelphia used a powerful new technology to RNA sequence 20,000 single nuclei, opening up the biological events behind heart disease.
https://www.creative-bioarray.com/services/stem-cell-research.htm
Epithelial cells from Creative Bioarray have been isolated from human normal, diseased donors of various tissues and animals such as mouse, rat, monkey and bovine with high purity, low passage, rigorously characterized, and performance tested.
https://www.creative-bioarray.com/filter/epithelial-cell-and-media-11.html
This study examined the accumulation of superparamagnetic iron oxide (SPIO) nanoparticles in vulnerable atherosclerotic plaques. In vitro experiments demonstrated that human macrophages actively take up fluorescent-labeled SPIO particles over 24 hours in a time- and concentration-dependent manner. In vivo studies in mice and rabbit models of atherosclerosis found SPIO particles in macrophage-rich areas of plaques, with a strong correlation between iron staining and foam cell density. Cytokine treatment increased SPIO uptake in plaques. The results suggest MRI using SPIO has potential for noninvasively assessing monocyte recruitment in vulnerable plaques.
This study examined the accumulation of superparamagnetic iron oxide (SPIO) nanoparticles in vulnerable atherosclerotic plaques. In vitro experiments demonstrated that human macrophages actively take up fluorescent-labeled SPIO particles over 24 hours in a time- and concentration-dependent manner. In vivo studies in mice and rabbit models of atherosclerosis found SPIO particles in macrophage-rich areas of plaques, with a strong correlation between iron staining and foam cell density. Cytokine treatment increased SPIO uptake in plaques. The results suggest MRI using SPIO has potential for noninvasively assessing monocyte recruitment in vulnerable plaques.
1) Human umbilical cord blood CD34+ enriched cells can engraft and develop in the bone marrow of irradiated NOD/LtSz-scid/scid mice without human growth factor support.
2) The human cells home to the mouse bone marrow and develop into myeloid, lymphoid, erythroid, and CD34+ progenitor populations, indicating development proceeds from primary hematopoietic sites to the periphery.
3) Repopulation of secondary recipients with human cells from primary recipient bone marrow demonstrates the human precursor population maintains substantial proliferative capacity.
Peripheral blood stem cell transplantation (PBSCT) involves collecting stem cells from a patient's bloodstream and later infusing them back into the patient after chemotherapy or radiation therapy. PBSCT has replaced bone marrow as the most common stem cell transplantation procedure. Stem cells are collected from the bloodstream using growth factors alone or with chemotherapy, and the minimum number needed for a safe transplant is 2 million CD34+ cells per kilogram of body weight. PBSCT results in faster recovery time compared to bone marrow transplants due to higher numbers of stem cells and T cells collected.
This document discusses a study evaluating the use of superparamagnetic iron oxide (SPIO) nanoparticles to non-invasively image macrophage infiltration in atherosclerotic plaques via MRI. Researchers injected SPIO into hypercholesterolemic and normal rabbits and found SPIO accumulation correlated with macrophage density in plaques, as observed via histology. SPIO-enhanced MRI identified inflamed plaques in hypercholesterolemic rabbits compared to normal rabbits. The study demonstrates SPIO nanoparticles can be used to non-invasively detect active inflammation in vulnerable atherosclerotic plaques.
Rna sequencing of cardiac cells may elucidate cardiac developmental mechanism...Bennie George
In animal studies, researchers identified multiple cell types in healthy and diseased hearts, and researchers also studied the ‘transcription blueprint’ in detail, where DNA transcribes genetic information into RNA and protein.
https://www.creative-bioarray.com/products/adult-stem-cells-34.htm
The Complete Guide to Know That RNA Sequencing of Cardiac Cells May Elucidate...Bennie George
A research report published in the international magazine Genes & Development, scientists from the Children's Hospital of Philadelphia used a powerful new technology to RNA sequence 20,000 single nuclei, opening up the biological events behind heart disease.
https://www.creative-bioarray.com/services/stem-cell-research.htm
Epithelial cells from Creative Bioarray have been isolated from human normal, diseased donors of various tissues and animals such as mouse, rat, monkey and bovine with high purity, low passage, rigorously characterized, and performance tested.
https://www.creative-bioarray.com/filter/epithelial-cell-and-media-11.html
Mouse Interleukin-13 (IL-13) is produced primarily by activated Th2 cells. IL-13 is a pleiotropic immune regulatory cytokine that promotes growth of human B cells; induces expression of germ line Ce transcripts, directs na?ve B cells to switch to the synthesis of IgE and IgG4, and induces expression of CD23 and Class II-MHC.
https://www.creative-bioarray.com/ActoFactor%E2%84%A2-Recombinant-Mouse-Interleukin-13-CSC-CTK0002-item-4204.htm
Creative Bioarray provides custom cell & tissue lysates service for all of our customers to meet their scientific requirements for downstream analysis. We provide different types of lysates from various species such as human, cynomolgus monkey, bovine, canine, mouse, rat, rabbit, ferret, zebrafish, and so on.
https://www.creative-bioarray.com/Services/custom-cell-tissue-lysates-service.htm
Fluorescence in situ hybridization (FISH), developed in 1980s, is a cytogenetic technique using fluorescent probes to bind the chromosome with a high degree of complementarity. It is a powerful and easy method to detect RNA or DNA sequences in cells, tissues and tumors.
https://www.creative-bioarray.com/services/Fluorescent-In-Situ-hybridization-FISH.htm
Ubiquitination is a key regulatory mechanism attaching the small protein modifier ubiquitin to protein substrates, thereby modifying their structure, cellular location, function, or targeting them for destruction via proteolysis.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/Ubiquitin-Screening-Profiling-Services.html
Creative Biogene offers a wide range of ABC transporters assays, including P-gp (MDR1/ABCB1), BCRP (ABCG2) and BSEP (sPgp/ABCB11), etc.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/ABC-transporters-Screening-and-Profilin-Assays.html
A methyl group from S-adenosyl-methionine (SAM) is transferred to the C5 position of the pyrimidine ring of cytosine residues by DNMTs in genomic CpG dinucleotides.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/DNA-Methyltransferase-Screening-and-Profiling.html
Creative Biogene offers epigenetic screening and profiling services to help with drug discovery. Their scientists provide expertise in epigenetics to advance drug programs targeting epigenetic mechanisms. They have high-throughput and customized assays to screen compound libraries against epigenetic targets or profile a drug's activity against multiple targets. Epigenetics involves heritable gene expression changes not from DNA alterations, and impacts many disease areas making it important for diagnostics and therapeutics.
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer. Research contains mechanism study (including molecule mechanism), pathological research, surgical method, medical treatment therapy (chemotherapy, radiotherapy), management for an individual patient, new drug development, etc. Obviously, oncology is often managed through discussion on multi-disciplinary.
https://www.creative-bioarray.com/oncology.htm
Creative Bioarray offers hERG safety assays conducted by experts to evaluate cardiovascular safety of compounds according to ICH S7B guidelines. The hERG assay tests inhibition of the potassium channel associated with prolonged QT interval and ventricular arrhythmias. Other ion channel inhibition assays are also available to support drug development and identify risks of delayed ventricular repolarization.
The principle function of epithelial cells is to provide a protective layer for the organ they enclose but also provide other biological functions including secretion, selective absorption, filtration, protection and detection of sensation.
https://www.creative-bioarray.com/filter/epithelial-cell-and-media-11.html
Virus packaging is a kind of biological technology, which is developed from the characteristics of virus replication. In this technology, virus packages the target gene into the structural and non structural proteins to produce viruses which have certain infectivity but have no pathogenicity.
https://www.creative-biogene.com/Product/Virus-Packaging-Kits.html
Kinases are a large family contains 518 members which represent one of the most important and largest superfamilies of drugable targets and a major research field for both the pharmaceutical industry and academic research.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/Kinase-Screening-Assays.html
New Findings in T cell Behavior Are Expected to Help Develop New Immunotherap...Bennie George
Recently, a research report published in the international journal Science Immunology, scientists from the University of Colorado found that the disease-resistant T cells obtained from the vaccine may not need glucose to rapidly multiply, related research results may provide new ideas and hopes for the development of new immunotherapy for cancer patients.
https://www.creative-bioarray.com/immuno-oncology.htm
The Complete Guide to Know That New Findings in T cell Behavior Are Expected ...Bennie George
The researchers analyzed patients who were vaccinated with subunit vaccines which are made with a portion of the disease virus to test the T cells produced in their immune systems. The researchers found that the key white blood cells (T cells) that attack and suppress infection do not rely on glucose to accelerate rapid cell division, the cell division will occur every 2-4 hours.
Baculovirus-Insect cell expression system is one of the most popular eukaryotic expression systems for research and industrial applications. There are several advantages of using the baculovirus-Insect cell expression system, such as improved solubility, ability to incorporate post-translational modifications, and higher yield of secreted proteins.
https://www.creative-biogene.com/Services/Baculovirus-Insect-cell-expression-system.html
Ion channels are pore-forming membrane proteins that create a gated, water-filled pore to help establish and control voltage potential across cell membranes through control of the active flow of ions between the intracellular and the extracellular environments.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/Ion-Channel-Screening-Assays.html
LAM PCR (Linear - amplification mediated PCR) is a technology which is used for identifying and characterizing unknown flanking DNA adjacent to known DNA of any origin. More specifically, LAM-PCR has been developed to localize viral vector integration sites (IS) within the host genome.
CRISPR/Cas9 system consists of a “guide” RNA (gRNA) and a bacterial CRISPR-associated endonuclease (Cas9). The gRNA is a short synthetic RNA composed of a Cas9-binding “scaffold” sequence and ∼20 nucleotide “targeting” sequence that defines the target genomic site to be modified.
https://www.creative-biogene.com/Services/Stable-cell-line-generation/Custom-Genome-Editing-Cell-Lines.html
The cell cycle is the most fundamental and important process by which eukaryotic cells duplicate and divide. The cell cycle consists of two specific and distinct phases: interphase, consisting of G1 (Gap 1), S (synthesis), and G2 (Gap 2), and the mitotic phase; M (mitosis).
https://www.creative-bioarray.com/cell-cycle-assays.htm
This document discusses apoptosis, or programmed cell death. It begins with an introduction to apoptosis, describing its role in development and disease prevention. It then covers the mechanisms of apoptosis, including the extrinsic and intrinsic pathways. Part 3 discusses how apoptosis helps eliminate infected or cancerous cells. Finally, Part 4 outlines several methods for detecting apoptosis, such as assays measuring plasma membrane alterations, caspase activation, mitochondrial changes, DNA fragmentation, and cytochrome C release.
Mouse Interleukin-13 (IL-13) is produced primarily by activated Th2 cells. IL-13 is a pleiotropic immune regulatory cytokine that promotes growth of human B cells; induces expression of germ line Ce transcripts, directs na?ve B cells to switch to the synthesis of IgE and IgG4, and induces expression of CD23 and Class II-MHC.
https://www.creative-bioarray.com/ActoFactor%E2%84%A2-Recombinant-Mouse-Interleukin-13-CSC-CTK0002-item-4204.htm
Creative Bioarray provides custom cell & tissue lysates service for all of our customers to meet their scientific requirements for downstream analysis. We provide different types of lysates from various species such as human, cynomolgus monkey, bovine, canine, mouse, rat, rabbit, ferret, zebrafish, and so on.
https://www.creative-bioarray.com/Services/custom-cell-tissue-lysates-service.htm
Fluorescence in situ hybridization (FISH), developed in 1980s, is a cytogenetic technique using fluorescent probes to bind the chromosome with a high degree of complementarity. It is a powerful and easy method to detect RNA or DNA sequences in cells, tissues and tumors.
https://www.creative-bioarray.com/services/Fluorescent-In-Situ-hybridization-FISH.htm
Ubiquitination is a key regulatory mechanism attaching the small protein modifier ubiquitin to protein substrates, thereby modifying their structure, cellular location, function, or targeting them for destruction via proteolysis.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/Ubiquitin-Screening-Profiling-Services.html
Creative Biogene offers a wide range of ABC transporters assays, including P-gp (MDR1/ABCB1), BCRP (ABCG2) and BSEP (sPgp/ABCB11), etc.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/ABC-transporters-Screening-and-Profilin-Assays.html
A methyl group from S-adenosyl-methionine (SAM) is transferred to the C5 position of the pyrimidine ring of cytosine residues by DNMTs in genomic CpG dinucleotides.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/DNA-Methyltransferase-Screening-and-Profiling.html
Creative Biogene offers epigenetic screening and profiling services to help with drug discovery. Their scientists provide expertise in epigenetics to advance drug programs targeting epigenetic mechanisms. They have high-throughput and customized assays to screen compound libraries against epigenetic targets or profile a drug's activity against multiple targets. Epigenetics involves heritable gene expression changes not from DNA alterations, and impacts many disease areas making it important for diagnostics and therapeutics.
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer. Research contains mechanism study (including molecule mechanism), pathological research, surgical method, medical treatment therapy (chemotherapy, radiotherapy), management for an individual patient, new drug development, etc. Obviously, oncology is often managed through discussion on multi-disciplinary.
https://www.creative-bioarray.com/oncology.htm
Creative Bioarray offers hERG safety assays conducted by experts to evaluate cardiovascular safety of compounds according to ICH S7B guidelines. The hERG assay tests inhibition of the potassium channel associated with prolonged QT interval and ventricular arrhythmias. Other ion channel inhibition assays are also available to support drug development and identify risks of delayed ventricular repolarization.
The principle function of epithelial cells is to provide a protective layer for the organ they enclose but also provide other biological functions including secretion, selective absorption, filtration, protection and detection of sensation.
https://www.creative-bioarray.com/filter/epithelial-cell-and-media-11.html
Virus packaging is a kind of biological technology, which is developed from the characteristics of virus replication. In this technology, virus packages the target gene into the structural and non structural proteins to produce viruses which have certain infectivity but have no pathogenicity.
https://www.creative-biogene.com/Product/Virus-Packaging-Kits.html
Kinases are a large family contains 518 members which represent one of the most important and largest superfamilies of drugable targets and a major research field for both the pharmaceutical industry and academic research.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/Kinase-Screening-Assays.html
New Findings in T cell Behavior Are Expected to Help Develop New Immunotherap...Bennie George
Recently, a research report published in the international journal Science Immunology, scientists from the University of Colorado found that the disease-resistant T cells obtained from the vaccine may not need glucose to rapidly multiply, related research results may provide new ideas and hopes for the development of new immunotherapy for cancer patients.
https://www.creative-bioarray.com/immuno-oncology.htm
The Complete Guide to Know That New Findings in T cell Behavior Are Expected ...Bennie George
The researchers analyzed patients who were vaccinated with subunit vaccines which are made with a portion of the disease virus to test the T cells produced in their immune systems. The researchers found that the key white blood cells (T cells) that attack and suppress infection do not rely on glucose to accelerate rapid cell division, the cell division will occur every 2-4 hours.
Baculovirus-Insect cell expression system is one of the most popular eukaryotic expression systems for research and industrial applications. There are several advantages of using the baculovirus-Insect cell expression system, such as improved solubility, ability to incorporate post-translational modifications, and higher yield of secreted proteins.
https://www.creative-biogene.com/Services/Baculovirus-Insect-cell-expression-system.html
Ion channels are pore-forming membrane proteins that create a gated, water-filled pore to help establish and control voltage potential across cell membranes through control of the active flow of ions between the intracellular and the extracellular environments.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/Ion-Channel-Screening-Assays.html
LAM PCR (Linear - amplification mediated PCR) is a technology which is used for identifying and characterizing unknown flanking DNA adjacent to known DNA of any origin. More specifically, LAM-PCR has been developed to localize viral vector integration sites (IS) within the host genome.
CRISPR/Cas9 system consists of a “guide” RNA (gRNA) and a bacterial CRISPR-associated endonuclease (Cas9). The gRNA is a short synthetic RNA composed of a Cas9-binding “scaffold” sequence and ∼20 nucleotide “targeting” sequence that defines the target genomic site to be modified.
https://www.creative-biogene.com/Services/Stable-cell-line-generation/Custom-Genome-Editing-Cell-Lines.html
The cell cycle is the most fundamental and important process by which eukaryotic cells duplicate and divide. The cell cycle consists of two specific and distinct phases: interphase, consisting of G1 (Gap 1), S (synthesis), and G2 (Gap 2), and the mitotic phase; M (mitosis).
https://www.creative-bioarray.com/cell-cycle-assays.htm
This document discusses apoptosis, or programmed cell death. It begins with an introduction to apoptosis, describing its role in development and disease prevention. It then covers the mechanisms of apoptosis, including the extrinsic and intrinsic pathways. Part 3 discusses how apoptosis helps eliminate infected or cancerous cells. Finally, Part 4 outlines several methods for detecting apoptosis, such as assays measuring plasma membrane alterations, caspase activation, mitochondrial changes, DNA fragmentation, and cytochrome C release.
2024 Media Preferences of Older Adults: Consumer Survey and Marketing Implica...Media Logic
When it comes to creating marketing strategies that target older adults, it is crucial to have insight into their media habits and preferences. Understanding how older adults consume and use media is key to creating acquisition and retention strategies. We recently conducted our seventh annual survey to gain insight into the media preferences of older adults in 2024. Here are the survey responses and marketing implications that stood out to us.
Ensure the highest quality care for your patients with Cardiac Registry Support's cancer registry services. We support accreditation efforts and quality improvement initiatives, allowing you to benchmark performance and demonstrate adherence to best practices. Confidence starts with data. Partner with Cardiac Registry Support. For more details visit https://cardiacregistrysupport.com/cancer-registry-services/
Basics of Electrocardiogram
CONTENTS
●Conduction System of the Heart
●What is ECG or EKG?
●ECG Leads
●Normal waves of ECG.
●Dimensions of ECG.
● Abnormalities of ECG
CONDUCTION SYSTEM OF THE HEART
ECG:
●ECG is a graphic record of the electrical activity of the heart.
●Electrical activity precedes the mechanical activity of the heart.
●Electrical activity has two phases:
Depolarization- contraction of muscle
Repolarization- relaxation of muscle
ECG Leads:
●6 Chest leads
●6 Limb leads
1. Bipolar Limb Leads:
Lead 1- Between right arm(-ve) and left arm(+ve)
Lead 2- Between right arm(-ve) and left leg(+ve)
Lead 3- Between left arm(-ve)
and left leg(+ve)
2. Augmented unipolar Limb Leads:
AvR- Right arm
AvL- Left arm
AvF- Left leg
3.Chest Leads:
V1 : Over 4th intercostal
space near right sternal margin
V2: Over 4th intercostal space near left sternal margin
V3:In between V2 and V4
V4:Over left 5th intercostal space on the mid
clavicular line
V5:Over left 5th intercostal space on the anterior
axillary line
V6:Over left 5th intercostal space on the mid
axillary line.
Normal ECG:
Waves of ECG:
P Wave
•P Wave is a positive wave and the first wave in ECG.
•It is also called as atrial complex.
Cause: Atrial depolarisation
Duration: 0.1 sec
QRS Complex:
•QRS’ complex is also called the initial ventricular complex.
•‘Q’ wave is a small negative wave. It is continued as the tall ‘R’ wave, which is a positive wave.
‘R’ wave is followed by a small negative wave, the ‘S’ wave.
Cause:Ventricular depolarization and atrial repolarization
Duration: 0.08- 0.10 sec
T Wave:
•‘T’ wave is the final ventricular complex and is a positive wave.
Cause:Ventricular repolarization Duration: 0.2 sec
Intervals and Segments of ECG:
P-R Interval:
•‘P-R’ interval is the interval
between the onset of ‘P’wave and onset of ‘Q’ wave.
•‘P-R’ interval cause atrial depolarization and conduction of impulses through AV node.
Duration:0.18 (0.12 to 0.2) sec
Q-T Interval:
•‘Q-T’ interval is the interval between the onset of ‘Q’
wave and the end of ‘T’ wave.
•‘Q-T’ interval indicates the ventricular depolarization
and ventricular repolarization,
i.e. it signifies the
electrical activity in ventricles.
Duration:0.4-0.42sec
S-T Segment:
•‘S-T’ segment is the time interval between the end of ‘S’ wave and the onset of ‘T’ wave.
Duration: 0.08 sec
R-R Interval:
•‘R-R’ interval is the time interval between two consecutive ‘R’ waves.
•It signifies the duration of one cardiac cycle.
Duration: 0.8 sec
Dimension of ECG:
How to find heart rhytm of the heart?
Regular rhytm:
Irregular rhytm:
More than or less than 4
How to find heart rate using ECG?
If heart Rhytm is Regular :
Heart rate =
300/No.of large b/w 2 QRS complex
= 300/4
=75 beats/mins
How to find heart rate using ECG?
If heart Rhytm is irregular:
Heart rate = 10×No.of QRS complex in 6 sec 5large box = 1sec
5×6=30
10×7 = 70 Beats/min
Abnormalities of ECG:
Cardiac Arrythmias:
1.Tachycardia
Heart Rate more than 100 beats/min
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Test bank clinical nursing skills a concept based approach 4e pearson educati...rightmanforbloodline
Test bank clinical nursing skills a concept based approach 4e pearson education
Test bank clinical nursing skills a concept based approach 4e pearson education
Test bank clinical nursing skills a concept based approach 4e pearson education
English Drug and Alcohol Commissioners June 2024.pptxMatSouthwell1
Presentation made by Mat Southwell to the Harm Reduction Working Group of the English Drug and Alcohol Commissioners. Discuss stimulants, OAMT, NSP coverage and community-led approach to DCRs. Focussing on active drug user perspectives and interests
Cyclothymia Test: Diagnosing, Symptoms, Treatment, and Impact | The Lifescien...The Lifesciences Magazine
The cyclothymia test is a pivotal tool in the diagnostic process. It helps clinicians assess the presence and severity of symptoms associated with cyclothymia.
The Ultimate Guide in Setting Up Market Research System in Health-TechGokul Rangarajan
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
"Market Research it too text-booky, I am in the market for a decade, I am living research book" this is what the founder I met on the event claimed, few of my colleagues rolled their eyes. Its true that one cannot over look the real life experience, but one cannot out beat structured gold mine of market research.
Many 0 to 1 startup founders often overlook market research, but this critical step can make or break a venture, especially in health tech.
But Why do they skip it?
Limited resources—time, money, and manpower—are common culprits.
"In fact, a survey by CB Insights found that 42% of startups fail due to no market need, which is like building a spaceship to Mars only to realise you forgot the fuel."
Sudharsan Srinivasan
Operational Partner Pitchworks VC Studio
Overconfidence in their product’s success leads founders to assume it will naturally find its market, especially in health tech where patient needs, entire system issues and regulatory requirements are as complex as trying to perform brain surgery with a butter knife. Additionally, the pressure to launch quickly and the belief in their own intuition further contribute to this oversight. Yet, thorough market research in health tech could be the key to transforming a startup's vision into a life-saving reality, instead of a medical mishap waiting to happen.
Example of Market Research working
Innovaccer, founded by Abhinav Shashank in 2014, focuses on improving healthcare delivery through data-driven insights and interoperability solutions. Before launching their platform, Innovaccer conducted extensive market research to understand the challenges faced by healthcare organizations and the potential for innovation in healthcare IT.
Identifying Pain Points: Innovaccer surveyed healthcare providers to understand their difficulties with data integration, care coordination, and patient engagement. They found widespread frustration with siloed systems and inefficient workflows.
Competitive Analysis: Analyzed competitors offering similar solutions in healthcare analytics and interoperability. Identified gaps in comprehensive data aggregation, real-time analytics, and actionable insights.
Regulatory Compliance: Ensured their platform complied with HIPAA and other healthcare data privacy regulations. This compliance was crucial to gaining trust from healthcare providers wary of data security issues.
Customer Validation: Conducted pilot programs with several healthcare organizations to validate the platform's effectiveness in improving care outcomes and operational efficiency. Gathered feedback to refine features and user interface.
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Sectional dentures for microstomia patients.pptxSatvikaPrasad
Microstomia, characterized by an abnormally small oral aperture, presents significant challenges in prosthodontic treatment, including limited access for examination, difficulties in impression making, and challenges with prosthesis insertion and removal. To manage these issues, customized impression techniques using sectional trays and elastomeric materials are employed. Prostheses may be designed in segments or with flexible materials to facilitate handling. Minimally invasive procedures and the use of digital technologies can enhance patient comfort. Education and training for patients on prosthesis care and maintenance are crucial for compliance. Regular follow-up and a multidisciplinary approach, involving collaboration with other specialists, ensure comprehensive care and improved quality of life for microstomia patients.
2. astrocytoma glioblastoma
cells
Creative Bioarray provides various human and animal cell lines that
are invaluable for medical, scientific and pharmaceutical
institutions. Creative Bioarray offers Astrocytoma/Glioblastoma
Cells for your research.
3.
4. Contact informationContact information
Provider: Creative BioarrayCreative Bioarray
URL: http://www.creative-bioarray.com/Products/Astrocytoma-Glioblastoma-Cells-http://www.creative-bioarray.com/Products/Astrocytoma-Glioblastoma-Cells-
list-89.htmlist-89.htm
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA
Phone No. 1-631-619-7922