Why asthma
is good
for your practice
Dr. Sujeet Rajan
Respiratory Physician
Bombay Hospital Institute of Medical Sciences
Great
opportunity
Easy
opportunity
Asthma is so common….
1 in 10 of your patients !
 Most patients prefer treatment from their
family doctor rather than a Chest
Physician
 Physicians / GPs can treat asthma just
as well as Chest Physicians ( even
better )
The 4 keys to
successful asthma practice
“Is it asthma?”
Just a few questions in
a few minutes
1
The 4 keys to
successful asthma practice
Treating the disease
2
Not much time
……..and easily.
The 4 keys to
successful asthma practice
Making things simple for
your patient
3
Child’s play
Low cost
The 4 keys to
successful asthma practice
Saying the right things
Answering patients’
questions
“Jo bolega, karega”
4
Which secret do you
want to unlock?
1. “Is it asthma?”
2. Treating the disease
3. Making things simple
4. Saying the right things
Diagnosis:
Why make it ?
 The patient has alternatives
(if you don’t, someone else will !)
 Excellent prognosis, esp. in children
 Treatment is so simple
Do I need a lot of tests?
Nothing usually, besides a
sharp history
What questions or
statements can suggest
asthma?
 Do you have a persistent cough ?
 Do you wheeze or often feel breathless while
coughing ?
 Do your symptoms worsen with climate
change, or dust /other allergens ?
What questions or
statements …
Do the symptoms get worse at
night ?
Do you get chest tightness with
the cough ?
Does it all start with a cold ?
Do your colds often “go down” into
the chest ?
What questions or
statements …
 Do your symptoms get worse after
extremes of happiness or sadness ?
(emotional swings)
 Do heavy meals or late nights worsen
your symptoms ? (GE reflux)
 Are your symptoms worse at work than
at home ? (occupational asthma)
What questions or
statements …
 Does anyone else in your family
suffer from any allergies ?
Ask about:
skin allergies
eczema
frequent colds
‘bronchitis’
What questions or
statements …
“I get relief with this medicine.”
Ask: which medicine?
(always check for bronchodilator)
Diagnosis in children
 Commonest cause of a persistent
cough is asthma
 Cough after exercise, activity, play
 Vomiting
 Failure to thrive
( poor sleep, poor growth )
When do you need lung
function tests ?
 Spirometry ( 250 to 350 rupees )
 To re-confirm the diagnosis
 When in doubt
 Normal Spirometry ( Challenge tests )
Things the patient may
not tell you …
Stigma and discrimination
from a “word”
Work/school absenteeism
Marital discord
Travel & holidays ‘controlled’
Other ‘advice’ the patient gets
Grandparents/neighbours/ ‘friends’ –
Inhalers ???
Steroids ???
Make the diagnosis but
emphasize the prognosis
Instead of asthma controlling your
patient,
the patient can control asthma
Asthma therapy in India today
Completely control symptoms and
fast
Normal life
As good as abroad ( even better )
General practice and physician level
Doesn’t need Chest Physicians !
Asthma Disease:
Spasm and swelling
 Spasm needs a reliever
Bronchodilator
 Swelling needs a contoller
Anti-inflammatory
Two types of drugs:
Reliever & Controller
Reliever
Bronchodilator (beta2 agonist)
Quickly relieves symptoms
(within 2-3 minutes)
Not for regular use
Reliever …
Inhaled
Nebulised
Oral
Most of the time
For severe attacks;
administer at your
clinic/hospital
Rarely needed
Anti-inflammatory
Takes time to act (1-3 hours)
Long-term effect (12-24 hours)
Only for regular use
(whether well or not well)
Controller
If your patient uses reliever
medication every day, or even
more than three or four times a
week, preventive medication
must be added to the treatment
plan.
GINA Workshop Report, December 1995
WHAT HAPPENS WHEN YOU
DON’T TREAT ASTHMA WELL
Normal
Inflamed
(Asthma)
Partly Treated
Fixed Obstruction
(Lead Pipe)
Remodelled
Airway
What is changing the lives
of our asthma patients
today?
Inhaled steroid
THE STORY OF ASTHMA
TREATMENT
Normal Inflamed (untreated)
Regular
Inhaled
Steroid
Partly
Treated
Corticosteroids are the most potent
and effective anti-inflammatory
medication currently available
for asthma*
*GINA (NHLBI & WHO Workshop Report), December 1995
*Guidelines for the diagnosis and management of Asthma NIH,
NHLBI, May 1997
Controller ..
Inhaled corticosteroids
 Budesonide/ beclomethasone/
fluticasone/ciclesonide – use any
 Start (400-1000 mcg/day approx. in
2 divided doses)
 Maintain for 3 months
 Taper slowly
 Safe for long-term use (years)
Controllers …
Inhaled corticosteroids: how safe?
 Even in small children for several
years
 30% of Olympic athletes
 Not anabolic (performance-enhancing)
steroid
 Even highest ICS dose is safer than
low dose oral steroid
 Best “Addiction” for asthmatics
Inhaled steroids : safe even
for children?
 400 mcg/day (budesonide)
 Over 13 years of continuous use
 No growth retardation
 Uncontrolled asthma causes growth
retardation
Pedersen & Agertoft NEJM 2000
Pregnancy and asthma
 Don’t x-ray (if possible)
 All asthma medication is safe
 Even oral corticosteroids are safe for
exacerbations
 Uncontrolled asthma during pregnancy
is a serious risk factor for foetal distress
and anoxia
Thorax
Inhaled Steroids Not
Working ?
Add SR
theophylline
Check Inhaler
Technique /
Check Regular Use
Add LABA
Formoterol /
Salmeterol
Increase dose
of inhaled
steroid
Add Leukotriene
modifier
Leukotriene Modifiers
 Oral anti-inflammatory
 Not as effective as inhaled steroid
 First-line for 2 to 5 yr. olds.
 All your ‘regular’ bronchodilator users.
Theophylline
 Sustained release for regular use
 Inexpensive , but toxic
 Not more than 600 mg per day usually
 Weak bronchodilator, but A-I effects
Add-on drugs : ICS + ?
1. Long acting Beta²-agonist ( LABA )
2. Montelukast
3. SR Theophylline
ICS + LABA
 Which ICS ?
Budesonide: Once daily
Even children < 4 years
Safe for long term use
ICS + LABA
Which LABA ?
Formoterol: Immediate relief (as fast as
salbutamol)
12 hours effect
Can be combined with
budesonide
Ideal combination
Formoterol ( fast relief and
sustained relief ) +
Budesonide ( twice or even
once daily use )
Dose: 1- 4 puffs ( OD/BD )
Can be used for relief as
well as control
FORACORT
Guidelines for using SMART
with FOACORT
• SMART means patients take a daily maintenance dose of
FORACORT and in combination take FORACORT as needed in
response to symptoms.
The recommended maintenance dosage is 2 inhalations per day
 Patients should take 1 additional inhalation as needed in
response to symptoms. If symptoms persist after a few minutes,
an additional inhalation should be taken. Not more than 6
inhalations should be taken on any single occasion.
 A total daily dose of up of 12 inhalations could be used for a
limited period.
 Patients using more than 8 inhalations daily should be strongly
recommended to seek medical advice.
Oral Steroid
 Prednisolone
 Acute severe episodes
(20-60 mg/day “burst”
along with bronchodilators)
 Dispense preferably
 Steroid-dependent asthma
Steroid-Dependent Asthma
A patient who requires regular
oral corticosteroids for control of
his/her asthma
Why doctors don’t use
inhalation therapy
 Status quo :
“my practice is good or ‘great’”
 Oral therapy is easy
 Too busy
 Cost
 Headache to explain
Which inhaler?
Inhalers
MDI DPIs Nebuliser
(acute severe
episodes only)
Scope for Inhalation
Therapy highest in a child
 < 5 yrs - High incidence of
wheezing
 Parents want the best for
their child
The Rotahaler
Has transformed inhalation therapy
Child’s play (Insert -Twist - Inhale)
Economical (Rs. 74)
Acceptable (v/s difficulties with MDI)
Every drug you need
Child below 3, or adult over 85
 MDI + Spacer
 MDI + Spacer + Baby Mask
When can you not use a
Rotahaler ?
Why use a Spacer ?
 Ensures correct use of an MDI by
correcting co-ordination problems.
 Reduces incidence of throat infections
with inhaled steroid
 As good as nebuliser for acute
exacerbations ( with MDI )
Then do we need nebulisers ?
– YES
 Acute severe asthma with impending
respiratory failure
 Intensive care / Hospital / Clinic /
Ambulances
Managing asthma in clinic
(patient who walks in wheezing quite badly)
 Oral prednisolone 20 mg/day x 1 week
 Foracort Rotacaps (100/200/400) (Form +
Bud) twice daily x 1 week and also as
rescue
Call patient after 1 week
If much better
Taper or omit Prednisolone
Continue Foracort Rotacaps
for 2 months in same dose
Foracort Rotacaps SOS
Call patient after 1 week …
If not much better /
still needs salbutamol often
Check Rotahaler Technique
Check whether using Foracort
regularly
If still not better at 2-3
months
 Consider adding SR theophylline or
montelukast
 Look for aggravating factors
– GE Reflux
– Emotions/ stress
– Sinusitis
– Allergic Rhinitis
– Persistent allergens
Always check
 Inhaler technique
 Regularity of steroid use
What do you tell patients ?
Oh no ! I have asthma ?
Allergic disorder (allergies don’t
have cures)
You could call it “allergic bronchitis”
To lead a normal life, accept regular
therapy (like DM/ HT/ Epilepsy)
What do you tell patients …
How long do I need this inhaler?
Wont I get addicted ?
 Inhalers are a delivery system, not the
drug
 The drug is in a “homeopathic” dose
 The earlier you start steroid, the better.
….. best “addiction”
 Untreated asthma will cripple you
What should you keep in
your asthma clinic ?
 Rotahaler/ Revolizer
 Placebo Rotacaps
 Placebo MDI/ Spacer/ Baby Mask
 Nebuliser ( for emergencies only )
 Height measure
 Breathe-o-meter
 Education material ( available in 9
languages )
The Breathe-o-Meter
like a thermometer for asthma
 Inexpensive clinic
instrument
 Monitoring
 Builds confidence in
treatment
 One ‘hard, fast blow’
The Breathe-o-Meter…
 First visit and follow-ups
 Improving symptoms
= improving peak flows
= improving confidence
 Rarely for home use
What do you tell patients …
Today’s asthmatics are suffering as
they never received regular inhaled
steroids as children.
What costs more is not better (e.g.
nebulisers for home use)
Examples
Myopics Spherical glasses regularly
Everyone Brushing teeth regularly
Obesity Diet & exercise regularly
Asthmatics Inhaled steroid regularly
Asthma management:
nothing specialist
about it
Dr. Sujeet Rajan
Respiratory Physician
Bombay Hospital Institute of Medical Sciences

Asthma_In_General_Practice_dec_2010.ppt

  • 1.
    Why asthma is good foryour practice Dr. Sujeet Rajan Respiratory Physician Bombay Hospital Institute of Medical Sciences
  • 2.
  • 3.
    Asthma is socommon…. 1 in 10 of your patients !  Most patients prefer treatment from their family doctor rather than a Chest Physician  Physicians / GPs can treat asthma just as well as Chest Physicians ( even better )
  • 4.
    The 4 keysto successful asthma practice “Is it asthma?” Just a few questions in a few minutes 1
  • 5.
    The 4 keysto successful asthma practice Treating the disease 2 Not much time ……..and easily.
  • 6.
    The 4 keysto successful asthma practice Making things simple for your patient 3 Child’s play Low cost
  • 7.
    The 4 keysto successful asthma practice Saying the right things Answering patients’ questions “Jo bolega, karega” 4
  • 8.
    Which secret doyou want to unlock? 1. “Is it asthma?” 2. Treating the disease 3. Making things simple 4. Saying the right things
  • 9.
    Diagnosis: Why make it?  The patient has alternatives (if you don’t, someone else will !)  Excellent prognosis, esp. in children  Treatment is so simple
  • 10.
    Do I needa lot of tests? Nothing usually, besides a sharp history
  • 11.
    What questions or statementscan suggest asthma?  Do you have a persistent cough ?  Do you wheeze or often feel breathless while coughing ?  Do your symptoms worsen with climate change, or dust /other allergens ?
  • 12.
    What questions or statements… Do the symptoms get worse at night ? Do you get chest tightness with the cough ? Does it all start with a cold ? Do your colds often “go down” into the chest ?
  • 13.
    What questions or statements…  Do your symptoms get worse after extremes of happiness or sadness ? (emotional swings)  Do heavy meals or late nights worsen your symptoms ? (GE reflux)  Are your symptoms worse at work than at home ? (occupational asthma)
  • 14.
    What questions or statements…  Does anyone else in your family suffer from any allergies ? Ask about: skin allergies eczema frequent colds ‘bronchitis’
  • 15.
    What questions or statements… “I get relief with this medicine.” Ask: which medicine? (always check for bronchodilator)
  • 16.
    Diagnosis in children Commonest cause of a persistent cough is asthma  Cough after exercise, activity, play  Vomiting  Failure to thrive ( poor sleep, poor growth )
  • 17.
    When do youneed lung function tests ?  Spirometry ( 250 to 350 rupees )  To re-confirm the diagnosis  When in doubt  Normal Spirometry ( Challenge tests )
  • 18.
    Things the patientmay not tell you … Stigma and discrimination from a “word” Work/school absenteeism Marital discord Travel & holidays ‘controlled’
  • 19.
    Other ‘advice’ thepatient gets Grandparents/neighbours/ ‘friends’ – Inhalers ??? Steroids ???
  • 20.
    Make the diagnosisbut emphasize the prognosis Instead of asthma controlling your patient, the patient can control asthma
  • 21.
    Asthma therapy inIndia today Completely control symptoms and fast Normal life As good as abroad ( even better ) General practice and physician level Doesn’t need Chest Physicians !
  • 22.
    Asthma Disease: Spasm andswelling  Spasm needs a reliever Bronchodilator  Swelling needs a contoller Anti-inflammatory
  • 23.
    Two types ofdrugs: Reliever & Controller Reliever Bronchodilator (beta2 agonist) Quickly relieves symptoms (within 2-3 minutes) Not for regular use
  • 24.
    Reliever … Inhaled Nebulised Oral Most ofthe time For severe attacks; administer at your clinic/hospital Rarely needed
  • 25.
    Anti-inflammatory Takes time toact (1-3 hours) Long-term effect (12-24 hours) Only for regular use (whether well or not well) Controller
  • 26.
    If your patientuses reliever medication every day, or even more than three or four times a week, preventive medication must be added to the treatment plan. GINA Workshop Report, December 1995
  • 27.
    WHAT HAPPENS WHENYOU DON’T TREAT ASTHMA WELL Normal Inflamed (Asthma) Partly Treated Fixed Obstruction (Lead Pipe) Remodelled Airway
  • 28.
    What is changingthe lives of our asthma patients today? Inhaled steroid
  • 29.
    THE STORY OFASTHMA TREATMENT Normal Inflamed (untreated) Regular Inhaled Steroid Partly Treated
  • 30.
    Corticosteroids are themost potent and effective anti-inflammatory medication currently available for asthma* *GINA (NHLBI & WHO Workshop Report), December 1995 *Guidelines for the diagnosis and management of Asthma NIH, NHLBI, May 1997
  • 31.
    Controller .. Inhaled corticosteroids Budesonide/ beclomethasone/ fluticasone/ciclesonide – use any  Start (400-1000 mcg/day approx. in 2 divided doses)  Maintain for 3 months  Taper slowly  Safe for long-term use (years)
  • 32.
    Controllers … Inhaled corticosteroids:how safe?  Even in small children for several years  30% of Olympic athletes  Not anabolic (performance-enhancing) steroid  Even highest ICS dose is safer than low dose oral steroid  Best “Addiction” for asthmatics
  • 33.
    Inhaled steroids :safe even for children?  400 mcg/day (budesonide)  Over 13 years of continuous use  No growth retardation  Uncontrolled asthma causes growth retardation Pedersen & Agertoft NEJM 2000
  • 34.
    Pregnancy and asthma Don’t x-ray (if possible)  All asthma medication is safe  Even oral corticosteroids are safe for exacerbations  Uncontrolled asthma during pregnancy is a serious risk factor for foetal distress and anoxia Thorax
  • 35.
    Inhaled Steroids Not Working? Add SR theophylline Check Inhaler Technique / Check Regular Use Add LABA Formoterol / Salmeterol Increase dose of inhaled steroid Add Leukotriene modifier
  • 36.
    Leukotriene Modifiers  Oralanti-inflammatory  Not as effective as inhaled steroid  First-line for 2 to 5 yr. olds.  All your ‘regular’ bronchodilator users.
  • 37.
    Theophylline  Sustained releasefor regular use  Inexpensive , but toxic  Not more than 600 mg per day usually  Weak bronchodilator, but A-I effects
  • 38.
    Add-on drugs :ICS + ? 1. Long acting Beta²-agonist ( LABA ) 2. Montelukast 3. SR Theophylline
  • 39.
    ICS + LABA Which ICS ? Budesonide: Once daily Even children < 4 years Safe for long term use
  • 40.
    ICS + LABA WhichLABA ? Formoterol: Immediate relief (as fast as salbutamol) 12 hours effect Can be combined with budesonide
  • 41.
    Ideal combination Formoterol (fast relief and sustained relief ) + Budesonide ( twice or even once daily use ) Dose: 1- 4 puffs ( OD/BD )
  • 42.
    Can be usedfor relief as well as control FORACORT
  • 43.
    Guidelines for usingSMART with FOACORT • SMART means patients take a daily maintenance dose of FORACORT and in combination take FORACORT as needed in response to symptoms. The recommended maintenance dosage is 2 inhalations per day  Patients should take 1 additional inhalation as needed in response to symptoms. If symptoms persist after a few minutes, an additional inhalation should be taken. Not more than 6 inhalations should be taken on any single occasion.  A total daily dose of up of 12 inhalations could be used for a limited period.  Patients using more than 8 inhalations daily should be strongly recommended to seek medical advice.
  • 44.
    Oral Steroid  Prednisolone Acute severe episodes (20-60 mg/day “burst” along with bronchodilators)  Dispense preferably  Steroid-dependent asthma
  • 45.
    Steroid-Dependent Asthma A patientwho requires regular oral corticosteroids for control of his/her asthma
  • 47.
    Why doctors don’tuse inhalation therapy  Status quo : “my practice is good or ‘great’”  Oral therapy is easy  Too busy  Cost  Headache to explain
  • 48.
    Which inhaler? Inhalers MDI DPIsNebuliser (acute severe episodes only)
  • 49.
    Scope for Inhalation Therapyhighest in a child  < 5 yrs - High incidence of wheezing  Parents want the best for their child
  • 50.
    The Rotahaler Has transformedinhalation therapy Child’s play (Insert -Twist - Inhale) Economical (Rs. 74) Acceptable (v/s difficulties with MDI) Every drug you need
  • 51.
    Child below 3,or adult over 85  MDI + Spacer  MDI + Spacer + Baby Mask When can you not use a Rotahaler ?
  • 53.
    Why use aSpacer ?  Ensures correct use of an MDI by correcting co-ordination problems.  Reduces incidence of throat infections with inhaled steroid  As good as nebuliser for acute exacerbations ( with MDI )
  • 54.
    Then do weneed nebulisers ? – YES  Acute severe asthma with impending respiratory failure  Intensive care / Hospital / Clinic / Ambulances
  • 55.
    Managing asthma inclinic (patient who walks in wheezing quite badly)  Oral prednisolone 20 mg/day x 1 week  Foracort Rotacaps (100/200/400) (Form + Bud) twice daily x 1 week and also as rescue
  • 56.
    Call patient after1 week If much better Taper or omit Prednisolone Continue Foracort Rotacaps for 2 months in same dose Foracort Rotacaps SOS
  • 57.
    Call patient after1 week … If not much better / still needs salbutamol often Check Rotahaler Technique Check whether using Foracort regularly
  • 58.
    If still notbetter at 2-3 months  Consider adding SR theophylline or montelukast  Look for aggravating factors – GE Reflux – Emotions/ stress – Sinusitis – Allergic Rhinitis – Persistent allergens
  • 59.
    Always check  Inhalertechnique  Regularity of steroid use
  • 60.
    What do youtell patients ? Oh no ! I have asthma ? Allergic disorder (allergies don’t have cures) You could call it “allergic bronchitis” To lead a normal life, accept regular therapy (like DM/ HT/ Epilepsy)
  • 61.
    What do youtell patients … How long do I need this inhaler? Wont I get addicted ?  Inhalers are a delivery system, not the drug  The drug is in a “homeopathic” dose  The earlier you start steroid, the better. ….. best “addiction”  Untreated asthma will cripple you
  • 62.
    What should youkeep in your asthma clinic ?  Rotahaler/ Revolizer  Placebo Rotacaps  Placebo MDI/ Spacer/ Baby Mask  Nebuliser ( for emergencies only )  Height measure  Breathe-o-meter  Education material ( available in 9 languages )
  • 63.
    The Breathe-o-Meter like athermometer for asthma  Inexpensive clinic instrument  Monitoring  Builds confidence in treatment  One ‘hard, fast blow’
  • 64.
    The Breathe-o-Meter…  Firstvisit and follow-ups  Improving symptoms = improving peak flows = improving confidence  Rarely for home use
  • 65.
    What do youtell patients … Today’s asthmatics are suffering as they never received regular inhaled steroids as children. What costs more is not better (e.g. nebulisers for home use)
  • 66.
    Examples Myopics Spherical glassesregularly Everyone Brushing teeth regularly Obesity Diet & exercise regularly Asthmatics Inhaled steroid regularly
  • 67.
    Asthma management: nothing specialist aboutit Dr. Sujeet Rajan Respiratory Physician Bombay Hospital Institute of Medical Sciences