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Michelle Sexton ND
Bastyr University Research Institute
      Liaison from ASA to the
 American Herbal Pharmacopoeia
“Back to Eden”
by Jethro Kloss
• Roy Upton : Native American Native t,
                                   studied the ethnobotany of the United
                                   States, Virgin Islands, China.
                                 • Director, Planetary Formulas




                                 • Executive director and editor of the
                                   American Herbal Pharmacopoeia®
                                 • Roy is co-founder, past president of the
                                   American Herbalists Guild
                                 • led grassroots political efforts to secure
                                   passage of the Dietary Supplement Health
                                   and Education Act (DSHEA)



                                   2012 winner of the American Society of
He has brought America's           Pharmacognosy (ASP) Varro. E. Tyler award for
collective knowledge of herbal     outstanding lifetime contributions to the field
medicine to the world stage.       of herbal medicine.
Cannabis interruptus




                Cannabis Time Line
                                     4
Historical Reference



Cannabis flower (huo ma hua; 火麻花), combined with datura flower (originally given as shan
    qie hua (山茄花; Datura spp., yang jin hua; 洋金花) (Dou 1127-1279)

                         1811: Homeopathic Materia medica

                                                              Amer ican M ater ia M edica,
                                                                 T her apeutics and
                                                                  Phar macognosy

                                                    D eveloping the L atest Acquir ed Know ledge of
                                                    D r ugs, and Especially of the D ir ect Action of
                                                   Single D r ugs U pon Exact Conditions of D isease,
                                                   w ith Especial Refer ence of the T her apeutics of
                                                           the Plant D r ugs of the Amer icas.

                                                                                    By
                                                                   F I N L EY EL L I N GWOOD , M .D .

                                                                                           1919
                                                   L at e Pr ofessor of M at er ia M edica and Ther apeut ics in Bennet t M edical College,
2013:
 Rolling out the Green Carpet:
  Welcoming Cannabis to the
American Herbal Pharmacopoeia


      Internationally regarded as among the most
      comprehensive, practically useful, and critically
      reviewed monographs in the world (literally)!
* Developed in collaboration with the University of Mississippi,
the only federally legal source of medicinal Cannabis in the US.

* Provides complete battery of physical and chemical tests for
identity, purity, quality, and potency.

* Provides key information on cultivation, harvest, drying,
storage, processing.

* Establishes criteria for foreign matter, moisture content,
microbiological burden, pesticide residues, residual solvents.

* Beautiful photographs and illustrations to facilitate
identification and quality assessment of crude material.

* Clarifies some of the misconceptions and myths about
different species.
* Provides a detailed review of the authoritative historical literature on the medicinal
uses of the plant.

* Presents a comprehensive review of modern clinical trials.

* Provides an overview of basic pharmacology and pre-clinical research and dosing

* Provides a complete review of safety including; adverse effects, contraindications,
carcinogenicity, interactions with conventional medications, use in pregnancy and
lactation, influence on driving, and toxicology.

* Outlines medical use of Cannabis according to Ayurvedic, Chinese, and Western
herbal medicine traditions.

* Presents an overview of the regulation of Cannabis domestically and worldwide.

* Separates wheat from chaff as to what is known about the appropriate and safe use
of Cannabis medicinally versus misperceptions of what many people believe.
The AHP Cannabis monograph has been developed by a multi-disciplinary cadre of
  historians, botanists, chemists, pharmacologists, pharmacognosists, pharmacists,
               physicians, and traditional herbal medicine practitioners.

                                             Therapeutics
Progress Report                              Pharmacokinetics
Complete drafts of the following sections:   Addiction & Dependence
(under development)                          Use as a substitute for alcohol withdrawals
                                             Effects on appetite
Quality Control                              Anti-Cancer Effects
History                                      Effects on the skin
Botany                                       Endocannabinoid system
Macroscopic & Microscopic Morphology         Effects on Migraines
Commercial Sources and Handling              Movement disorders (MS, epilepsy,
Constituents                                 Parkinson's, Tourette's, ALS)
Thin Layer Chromatography (TLC)              Nausea-Vomiting
Gas Chromatography                           Ophthalmology
International Status                         Anxiety
HPLC                                         Gynecology
Pesticide, microbiological and               Pain
residual solvents limits                     Cancer
                                             Safety
                                             Alzheimer’s
                                             Traditional Herbal Medicine supplement
Saturday Afternoon: 4:30-6:00
     Exciting Developments in Medical Cannabis
More detailed description of the monograph and other
 strategies for navigating regulation in your locale!

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Science of Medical Cannabis - Michelle Sexton

  • 1. Michelle Sexton ND Bastyr University Research Institute Liaison from ASA to the American Herbal Pharmacopoeia
  • 2. “Back to Eden” by Jethro Kloss
  • 3. • Roy Upton : Native American Native t, studied the ethnobotany of the United States, Virgin Islands, China. • Director, Planetary Formulas • Executive director and editor of the American Herbal Pharmacopoeia® • Roy is co-founder, past president of the American Herbalists Guild • led grassroots political efforts to secure passage of the Dietary Supplement Health and Education Act (DSHEA) 2012 winner of the American Society of He has brought America's Pharmacognosy (ASP) Varro. E. Tyler award for collective knowledge of herbal outstanding lifetime contributions to the field medicine to the world stage. of herbal medicine.
  • 4. Cannabis interruptus Cannabis Time Line 4
  • 5. Historical Reference Cannabis flower (huo ma hua; 火麻花), combined with datura flower (originally given as shan qie hua (山茄花; Datura spp., yang jin hua; 洋金花) (Dou 1127-1279) 1811: Homeopathic Materia medica Amer ican M ater ia M edica, T her apeutics and Phar macognosy D eveloping the L atest Acquir ed Know ledge of D r ugs, and Especially of the D ir ect Action of Single D r ugs U pon Exact Conditions of D isease, w ith Especial Refer ence of the T her apeutics of the Plant D r ugs of the Amer icas. By F I N L EY EL L I N GWOOD , M .D . 1919 L at e Pr ofessor of M at er ia M edica and Ther apeut ics in Bennet t M edical College,
  • 6. 2013: Rolling out the Green Carpet: Welcoming Cannabis to the American Herbal Pharmacopoeia Internationally regarded as among the most comprehensive, practically useful, and critically reviewed monographs in the world (literally)!
  • 7.
  • 8. * Developed in collaboration with the University of Mississippi, the only federally legal source of medicinal Cannabis in the US. * Provides complete battery of physical and chemical tests for identity, purity, quality, and potency. * Provides key information on cultivation, harvest, drying, storage, processing. * Establishes criteria for foreign matter, moisture content, microbiological burden, pesticide residues, residual solvents. * Beautiful photographs and illustrations to facilitate identification and quality assessment of crude material. * Clarifies some of the misconceptions and myths about different species.
  • 9.
  • 10. * Provides a detailed review of the authoritative historical literature on the medicinal uses of the plant. * Presents a comprehensive review of modern clinical trials. * Provides an overview of basic pharmacology and pre-clinical research and dosing * Provides a complete review of safety including; adverse effects, contraindications, carcinogenicity, interactions with conventional medications, use in pregnancy and lactation, influence on driving, and toxicology. * Outlines medical use of Cannabis according to Ayurvedic, Chinese, and Western herbal medicine traditions. * Presents an overview of the regulation of Cannabis domestically and worldwide. * Separates wheat from chaff as to what is known about the appropriate and safe use of Cannabis medicinally versus misperceptions of what many people believe.
  • 11. The AHP Cannabis monograph has been developed by a multi-disciplinary cadre of historians, botanists, chemists, pharmacologists, pharmacognosists, pharmacists, physicians, and traditional herbal medicine practitioners. Therapeutics Progress Report Pharmacokinetics Complete drafts of the following sections: Addiction & Dependence (under development) Use as a substitute for alcohol withdrawals Effects on appetite Quality Control Anti-Cancer Effects History Effects on the skin Botany Endocannabinoid system Macroscopic & Microscopic Morphology Effects on Migraines Commercial Sources and Handling Movement disorders (MS, epilepsy, Constituents Parkinson's, Tourette's, ALS) Thin Layer Chromatography (TLC) Nausea-Vomiting Gas Chromatography Ophthalmology International Status Anxiety HPLC Gynecology Pesticide, microbiological and Pain residual solvents limits Cancer Safety Alzheimer’s Traditional Herbal Medicine supplement
  • 12. Saturday Afternoon: 4:30-6:00 Exciting Developments in Medical Cannabis More detailed description of the monograph and other strategies for navigating regulation in your locale!