This document discusses several key chemicals used in perfumes and their properties. It describes how many modern perfumes contain synthesized odorants that can provide scents not found in nature. Some examples of synthetic aromatics discussed include methyl anthranilate, methyl cinnamate, ethanol, citronellol, coumarin, and heliotrope. Each chemical is then described in more detail, outlining their molecular structure, scent properties, and common uses in perfumes and flavorings. Health concerns are also noted for some chemicals like coumarin.

1. ARTIFICIAL AND
PERFUMES FLAVORS

2. SYNTHESIZED PERFUMES
• INTRODUCTION
• Many modern perfumes contain synthesized odorants. Synthetics
can provide fragrances which are not found in nature. For
instance, Calone, a compound of synthetic origin, imparts a fresh
ozonous metallic marine scent that is widely used in contemporary
perfumes. Synthetic aromatics are often used as an alternate
source of compounds that are not easily obtained from natural
sources. For example, linalool and coumarin are both naturally
occurring compounds that can be inexpensively synthesized
from terpenes. Orchid scents (typically salicylates) are usually not
obtained directly from the plant itself but are instead synthetically
created to match the fragrant compounds found in various orchids.

3. TYPES OF CHEMICALS IN PERFUMES
• METHYL ANTHRANILATE
• METHYL CINNAMATE
• ETHANOL
• CITRONELLOL
• CUOMARIN
• HELIOTROPE

4. METHYL ANTHRANILATE
• Methyl anthranilate, also known as MA, methyl 2-aminobenzoate,
or carbomethoxyaniline, is an ester of anthranilic acid. Its chemical formula
is C8H9NO2. It has a fruity grape smell, and one of its key uses is as a flavoring
agent.
• It is a clear to pale yellow liquid with melting point 24 °C and boiling point
256 °C. It has a density of 1.168 g/cm3at 20 °C.[1] It has a refractive index of
1.583 at 589 nm of wavelength and 20 °C.[2] It shows a light blue-
violet fluorescence. It is very slightly soluble in water, and soluble
in ethanol and propylene glycol. It is insoluble in paraffin oil. It is
combustible, with flash point at 104 °C. At full concentration, it has a fruity
grape smell; at 25 ppm it has a sweet, fruity, Concord grape-like smell with
a musty and berry nuance.

5. • In a perfumery context the most common Schiff's Base is known as
aurantiol,[7]produced by combining methyl anthranilate and
hydroxycitronellal.

6. METHYL SALICYLATE
• wintergreen mint: aromatic, sweet, curative, phenolic Flavor: sweet, wintergreen :
minty; spicy; sweet acacia cassie farnesiana alpine bouquet apple apricot blackberry
blueberry boxwoodberry bubble gum carnation dianthus oeillet cassia cassia
blossom cassis black currant bud castoreum cherry chypre clove cornmint crabapple
blossom cranberry currant date fern fougere gardenia gooseberry grape hay new
mown hay foin coupe herbal huckleberry bilberry hyssop jasmin leather russian
licorice magnolia meadowsweet spiraea mimosa mint mulberry oriental peach
peppermint raspberry reseda mignonette root beer rue sassafras spearmint spice
spicewood strawberry tea green tuberose valerian wallflower wintergreen
wormwood absinthium ylang ylang zibeline birch beer cassis black currant bud
cornmint grenadine hyssop rue sarsaparilla tomato valerian wormwood
absinthiumbilberry : cassie absolute @ 94.40pc: : champaca absolute (michelia alba
dc.) @ 0.02pc: : champaca concrete @ 0.15pc: : couroup
• Relative Odor Impact100
• Odor Life on a smelling strip 88

7. • Product
• Methyl salicylate -colorless to pink clear liquid
• Specific Gravity -1.18
• Physical State-1.535
• Melting Point- -8
• Boiling Point-222

8. METHYL CINNAMATE

9. • Methyl cinnamate is the methyl ester of cinnamic acid and is a white or
transparent solid with a strong, aromatic odor. It is found naturally in a
variety of plants, including in fruits, like strawberry, and some culinary
spices, such as Sichuan pepper and some varieties of basil.[3] Eucalyptus
olida has the highest known concentrations of methyl cinnamate (98%) with
a 2–6% fresh weight yield in the leaf and twigs.[4]
• Methyl cinnamate is used in the flavor and perfume industries. The flavor is
fruity and strawberry-like; and the odor is sweet, balsamic with fruity odor,
reminiscent of cinnamon and strawberry.[1]
• It is known to attract males of various orchid bees, such as Aglae caerulea

10. ETHANOL
• Ethanol extraction: A type of solvent extraction used to extract
fragrant compounds directly from dry raw materials, as well as the
impure oily compounds materials resulting from solvent extraction
or enfleurage. Ethanol extraction from fresh plant materials contain
large quantities of water, which will also be extracted into the
ethanol.

11. CITRONELLOL
• At present, the world annual production of citronella oil is approximately
4,000 tonnes. The main producers are China and Indonesia - producing 40
percent of the world's supply. The oil is also produced in Taiwan, Guatemala,
Honduras, Brazil, Sri Lanka, India, Argentina, Ecuador, Jamaica, Madagascar,
Mexico, and South Africa.
• The market for natural citronella oil has been eroded by chemicals
synthesised from turpentine derived from conifers. However, natural
citronella oil and its derivatives are preferred by the perfume industry.

13. VANILLIN

14. COUMARIN
• Coumarin is subject to restrictions on its use in perfumery,[40] as some people
may become sensitized to it, however the evidence that coumarin can cause an
allergic reaction in humans is disputed.[41]
• Minor neurological dysfunction was found in children exposed to the
anticoagulants acenocoumarol or phenprocoumon during pregnancy. A group of
306 children were tested at ages 7–15 years to determine subtle neurological
effects from anticoagulant exposure. Results showed a dose response
relationship between anticoagulant exposure and minor neurological
dysfunction. Overall, a 1.9 (90%) increase in minor neurological dysfunction was
observed for children exposed to these anticoagulants, which are collectively
referred to as "coumarins." In conclusion, researchers stated, "The results
suggest that coumarins have an influence on the development of the brain which
can lead to mild neurologic dysfunctions in children of school age