Anti-depressants | Psychotropic Drugs | Mental Health | Juhin J
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Antidepressants are used to relieve the symptoms of moderate and severe depression. They are usually taken for 4-6 months. They can be used alone or combination with other medications. The purpose of antidepressant is to increase the neurotransmitters in the synapse.
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Anti-depressants | Psychotropic Drugs | Mental Health | Juhin J
- 1. ANTI DEPRESSANTS JUHIN J 1ST YEAR MSC NURSING
- 2. Objectives: At the end of this session, you’ll get clear understanding about; • What is meant by anti depressants • Action of antidepressants • Indications of antidepressants • Types of antidepressants
- 3. ANTI DEPRESSANTS • Antidepressants are used to relieve the symptoms of moderate and severe depression. • They are usually take for 4-6 months. • They can be used alone or combination with other medications. • The purpose of antidepressant is to increase the neurotransmitters in the synapse.
- 4. ACTION • Antidepressants works to increase the concentration of nor epinephrine, serotonin and dopamine in the body. • This is accomplished in the brain by blocking the reuptake of these neurotransmitters. • It takes 10-12 days to achieve the therapeutic maximum effect.
- 5. INDICATIONS • Dysthymic disorder • Major depression with psychotic symptoms • Melancholia • Depression associated with organic disease • Alcoholism • Schizophrenia with mental retardation • Depressive phase of bipolar disorder • Depression accompanied by anxiety
- 6. TYPES OF ANTIDEPRESSANTS Tricyclics 01 02 SSRI 03 04 05 Heterocyclics MAOI NSRI • Amitriptylline • Clomipramine • Imipramine • Mirtazapine • Trazadone • Citalopram • Fluoxetine • Fluvoxamine • Paroxetine • Sertraline • Venlafaxin
- 7. TRICYCLICS DRUG NAME USED FOR AVAILABLE FORMS MAXMIUM DOSE SIDE EFFECTS NURSES RESPONSIBILITY Amitriptylline • Depression illness • Nocturnal enuresis in children • 25 mg • 75 mg 250 mg • Hypotension • Blurred vision • Constipation • Urinary retention • Reducation in seizure threshold • Tachycardia • Arrhythmias • Photosensitivity • Weight gain • Follow the medications • Not to double dose • Not to discontinue • Be careful while driving • Avoid alcohol • Use sunscreen & large screen Clomipramide • Depression illness • Phobia • OCD • Cataplexy associated with narcolepsy • 25 mg • 75 mg 900 mg Imipramine • Depression illness • Nocturnal enuresis in children • 25 mg • 75 mg 350-400 mg
- 8. HETEROCYCLICS DRUG NAME USED FOR AVAILABLE FORMS MAXMIUM DOSE SIDE EFFECTS NURSES RESPONSIBILITY Miratazapine • Depression illness • 7.5 mg • 15 mg • 30 mg 45 mg • Drowsiness • Weight gain • Dry mouth • Increased appetite • Constipation • Lack of energy • Weakness • Dizziness • Muscle pain • Confusion • Tremor • Back pain • Shortness of breath • Follow the medications • Not to double dose • Not to discontinue abruptly • Assess BP • Provide seizure precautions • Be careful while driving • Avoid alcohol • Serotonin syndrome • Not to crush, break or chew ODT products • Not to use within 14 days of MAOI’s Trazadone • Depression illness • Sedation • 25 mg • 50 mg 100 mg
- 9. SSRI DRUG NAME USED FOR AVAILABLE FORMS MAXMIUM DOSE SIDE EFFECTS NURSES RESPONSIBILITY Citalopram • Depression illness • Panic disorder • 10 mg • 20 mg 80 mg • Insomnia • Aggitation • Headache • Weight loss • Aexual dysfunstion • Serotonin syndrome • Changes in mental status • Restlessness • Myoclonus • Hyper reflexia • Tachycardia • Labile blood pressure • Shivering • Increased anxiety – 5 to 7 days • Follow the medications • Not to double dose • Not to discontinue • Serotonin syndrome • Be careful while driving • Avoid alcohol • Use sunscreen & large screen Fluoxetine • Depression illness • Bulimia nervosa • OCD • Premenstrual Dysphonic disorder • 20 mg • 40 mg 80 mg Fluvoxamine • Depression illness • OCD • 50 mg • 100 mg 300 mg Peroxetine • Depressive illness • OCD • Panic disorder • Social phobia, PTSD • 20 mg • 30 mg 60 mg Sertraline • Depressive illness • OCD • Panic disorder • 25 mg • 50 mg • 100 mg 200 mg
- 10. NSRI DRUG NAME USED FOR AVAILABLE FORMS MAXMIUM DOSE SIDE EFFECTS NURSES RESPONSIBILITY Venlafaxin • Depression illness • Generalized anxiety disorder • 50 mg • 100 mg 375 mg • Headaches • Sweating • Dry mouth • Trouble sleeping • Feeling dizzy • Feeling sleepy • Constipation • Chest pain • Bleeding • Not to double dose • Not to discontinue • Avoid spicy food • Drink plenty water • Avoid driving • Take fibre rich diet
- 11. ANY DOUBTS
- 12. THANK YOU