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Emergence of Antibiotic resistance
Antibiotics are powerful drugs that kill or inhibit the
growth of bacteria.
Antibiotic Do
Work Aginst
Antibiotic Do
Not Work Aginst
VIRUS FUNGUS BACTERIA
Mechanism of Antibiotic Action
Inhibition of
cell wall
synthesis
Cell Wall
e.g. Penicillins,
Cephalosporin
Ribosome
Inhibition of
protein
synthesis
e.g.Tetracyclines
DNA
Inhibition of
nucleic acid
synthesis
e.g. Quinolones.
Block pathways
and inhibit
metabolism
Folic Acid
e.g. Sulphonamides,
Trimethoprim
Disruption of
cell membrane
function
Cell
Membrane
e.g. Rifampicin
Antibiotic Resistance Facts
Antibiotic resistance happens when bacteria change and become
resistant to the antibiotics used to treat the infections they cause
Patients not
finishing their
treatment
Lack of hygiene
and poor
sanitation
Over prescribing
of antibiotics
Poor infection
control in
hospitals
Over use of
antibiotics in
animals
Lack of new
antibiotics being
develpoed
Common
Causes of
Antibiotic
Resistance
Resistant Infections are Dangerous
❑ Medication toxicity (side effects)
❑ Contagious
❑ Can pass resistance to other
organisms
Worst Case Scenario: The infection may
become resistant to all medications (untreatable).
Global Impact of Resistant
❑ It is estimated that bacterial AMR was directly responsible for
1.27 million global deaths in 2019 and contributed to 4.95 million
deaths
❑ The World Bank estimates that AMR could result in US$ 1 trillion
additional healthcare costs by 2050, and US$ 1 trillion to
US$ 3.4 trillion gross domestic product (GDP) losses per year by 2030
Global Impact of Resistant
Venus
Venus is the
second planet
from the Sun
2
Earth
Earth is the
planet where
we all live on
3
Mercury
It’s the
smallest
planet in the
Solar System
5
Saturn
Saturn is a
gas giant and
has several
rings
6
Venus
Despite being
red, it’s
actually a
cold place
1
Jupiter
It’s the
biggest
planet in the
Solar System
4
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx
Antibiotic Resistance and their impact-1.pptx

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Antibiotic Resistance and their impact-1.pptx

  • 1.
  • 2.
  • 4. Antibiotics are powerful drugs that kill or inhibit the growth of bacteria. Antibiotic Do Work Aginst Antibiotic Do Not Work Aginst VIRUS FUNGUS BACTERIA
  • 5. Mechanism of Antibiotic Action Inhibition of cell wall synthesis Cell Wall e.g. Penicillins, Cephalosporin Ribosome Inhibition of protein synthesis e.g.Tetracyclines DNA Inhibition of nucleic acid synthesis e.g. Quinolones. Block pathways and inhibit metabolism Folic Acid e.g. Sulphonamides, Trimethoprim Disruption of cell membrane function Cell Membrane e.g. Rifampicin
  • 6. Antibiotic Resistance Facts Antibiotic resistance happens when bacteria change and become resistant to the antibiotics used to treat the infections they cause Patients not finishing their treatment Lack of hygiene and poor sanitation Over prescribing of antibiotics Poor infection control in hospitals Over use of antibiotics in animals Lack of new antibiotics being develpoed Common Causes of Antibiotic Resistance
  • 7. Resistant Infections are Dangerous ❑ Medication toxicity (side effects) ❑ Contagious ❑ Can pass resistance to other organisms Worst Case Scenario: The infection may become resistant to all medications (untreatable).
  • 8. Global Impact of Resistant ❑ It is estimated that bacterial AMR was directly responsible for 1.27 million global deaths in 2019 and contributed to 4.95 million deaths ❑ The World Bank estimates that AMR could result in US$ 1 trillion additional healthcare costs by 2050, and US$ 1 trillion to US$ 3.4 trillion gross domestic product (GDP) losses per year by 2030
  • 9.
  • 10.
  • 11.
  • 12.
  • 13. Global Impact of Resistant Venus Venus is the second planet from the Sun 2 Earth Earth is the planet where we all live on 3 Mercury It’s the smallest planet in the Solar System 5 Saturn Saturn is a gas giant and has several rings 6 Venus Despite being red, it’s actually a cold place 1 Jupiter It’s the biggest planet in the Solar System 4