This document discusses the emergence of antibiotic resistance. It explains that antibiotics work by inhibiting bacterial growth through various mechanisms, but bacteria can evolve and become resistant. Common causes of resistance include patients not finishing their treatment, overuse of antibiotics, and lack of new antibiotic development. Resistant infections are dangerous as they can be untreatable and spread resistance to other organisms. The global impact of antibiotic resistance is estimated to have directly caused over 1 million deaths in 2019 and predicted to result in significant healthcare costs and economic losses by 2050.