19. The Tale of a
“Yak-odisiac”
• Yak brought to higher
grounds in the Spring would
selectively graze in the new
grass.
• Once the ate whatever it
was they were looking for
they became “friskier”.
• Turns out they were eating
the Cordyceps.
• Word travelled to the
Imperial Court
• Thus the fame of this
“Yakodisiac” came to be.
21. Cordyceps’ Traditional Uses
• Yang Qi tonic
• Anti-aging
• Enriches the Kidneys (Jing) & protects the Lungs
(Qi)
• Dissolves phlegm
• Heart and cardiovascular tonic
• Enhance depressed immune function
• Calm over active immune system
• Sexual function restorative
27. Reishi-Ganoderma lucidum
Ling zhi (Spirit Plant)
Mushroom of Immortality
“…over a long period of
time, agility of the body will
not cease, and the years are
lengthened to those of the
Immortal Fairies.”
28. Reishi & TCM
• A traditional tonic to nourish,
tonify and supplement the
whole body
• Strengthens the lungs, protects
and stimulates the liver and
helps the body adapt to stress
• Removes toxins and disperses
accumulation
38. Specific cancers tested with Chaga
• Human colon carcinoma
• Human gastric carcinoma
• Human breast adenocarcinoma
• Human hepato-cellular
carcinoma
• Human HeLa cervical
carcinoma
• Murine melanoma
• Human lung carcinoma
• Sarcomas
40. New to the West - Meshima
• Phellinus linteus
• Japanese call it
“Meshimakobu”
• Grows on Mulberry, Elm
and Willows
• Thousands of years of
use in traditional
medicine
• Nutrient-dense
42. Immune Actions of Phellinus linteus
• Top immune enhancer out of ~20 medicinal mushrooms
• Study: 500 mg for 30 days
– Increased wbc ~11-81%
• Activates B cells
• Stimulates T lymphocytes
• Activates macrophage
• Orally effective
51. Problem with Diagnosis &
Treatment
1) Currently all medicine can do is maybe slow
progression
2) AD develops over a long time period with no signs or
symptoms
3) With too late of a diagnosis, neurons may be dead and
circuits may be destroyed
4) Almost impossible at this point to restore
5) PREVENT PREVENT PREVENT
52. What is alzheimer’s disease?
– memory loss
– language deterioration
– impaired ability to manipulate visual information
– poor judgment
– confusion
– restlessness
– mood swings
Eventually leads to loss of cognition, personality and
function
53.
54.
55.
56.
57. So what kind of a disease is
alzheimer’s?
Brain
Central Nervous System
What about?
Inflammatory
Immune
Cardiovascular
Free Radical
Endocrine
58. Is there hope?
Encarta World English Dictionary:
“senile dementia - a form of brain
disorder marked by progressive
and irreversible mental
deterioration, memory loss and
disorientation…”
63. Amyloban 3399™
Contains Standardized Extracts of:
• Hericenones
► Stimulate production of Nerve Growth Factor
• Amyloban
► May prevent death of nerve cells caused by amyloid
beta peptides.
► Patented (Japanese Patent # 3943399)
64. Lion’s Mane Nerve Support
• Induction of NGF
• Inhibition of the cytotoxicity of
β-amyloid peptide
• Protection against neuronal cell
death
• Stimulates myelination
• Anti-oxidant properties
• Hypoglycemic effects
• Immune enhancement
65. Effects of Lion’s Mane
on Nerve Cell Protection
• Looked at ER stress
induced neuronal cell
death
• Effectively protected cells
from death
Note: the crude extract,
Amyloban, appeared more
effective than purified DLPE
66. Lion’s Mane Clinical Study
• Rehabilitative hospital, Japan; elderly with degenerative diseases
• 6 of 7 dementia Patients improved perceptual capacities
• Marked improvements in patients evaluated by Functional Independence
Measure
• Appears to cross blood brain barrier
• Two other studies-retarded progression improved cognition
68. Lion’s Mane for Cognitive
Impairment
• 18 patients with mild to moderate impairment
• 1.5 grams of Lion’s Mane, 2x a day
• Results:
– 9 of 18 saw improvement
– 7 of 18 saw no change *
– 2 of 18 got worse
69. Case Report on Amyloban
Before
• Anxious, hostile,
impatient
• 29 dementia score
• 4 years ago, couldn’t
name 4 vegetables
• Couldn’t cook
• “Scary” dreams
• Restless & uneasy
• Couldn’t do simple math
70. Case Report on Amyloban
After
• Even temperament
• Normal score
• Can name as many as you
want
• Cooking
• Dreams of teaching dance
• Calm & comfortable
• Now she can
75. Schizandra, Traditional Tonic
Use for 100 days in a row:
• purify blood
• sharpen mind
• improve memory
• rejuvenate Qi
• cause skin to become radiantly
beautiful
76. The Story of Yang Guifei
One of China 4 most
beautiful women
Said to be so beautiful
that flowers would bow
before her beauty
One of her beauty
secrets: Tremella
Tremella is a traditinal
Yin tonic
81. Tonic Uses of Ginseng
• Strengthen the whole body
• Improve overall functioning
• Normalizing action on the body
• Restorative & rejuvenating
• “Tonic” to central nervous system, digestive &
respiratory tract
• Ultimate adaptogen
•Builds and supports all 3 Treasures
Qi, Shen and Jing
• “Closest thing to a panacea that we have”
82. He shou wu
• Li Ching Yuen 256 yrs. Old
• Yin Jing tonic
• Increases SOD activity
• 50 yr old - grey hair black
• 100 yr old - youthfulness
• 300 yr old - immortality
88. Pre-Clinical Studies
3 studies tested Lion’s Mane:
① 7 patients with dementia were given LM powder, showed
improvement in daily living activity
② 15 patients with dementia showed similar improvement
with LM tablets.
③ 7 patients with Alzheimer’s showed improvement in their
peripheral symptoms with LM tablets (wandering,
aggressiveness).
This is going to be something like a tasting to peak your interestInterestof mine is to track traditional uses of remedies and compare more recent “scientific” research with it.
Today I am going to be talking about: #1 - A new “old” approach to health& healing #2 - And possibly a new goalNot just elimination of symptoms Or even just preventionWe hear a lot about “healthcare” in a system devoted to symptom and disease care a disease management system
Dose dependent suppressed colony formation
Mushrooms and fungi’s benefits are broad and promising, esp. for the world today Fungi are the Great Recyclers for the planetMyco-remediation comparison study bound better than traditional remediation techniquesRadiation - chelator, radio-active sites, protects body
2,000,000 # of serious adverse drug side effects (year 2000) 284,000 - iatrogenic deaths - nice way of saying medicine caused - hospitals 3rd – leading cause of death - ahead of accidents, auto deaths, diabetes,…13th - infant mortality rate among “modern” or “advanced” nations - Out of 16 48th - rank of U.S. lifespan 40-60% - projected obesity rate for 2030 - BMI of 40% or higher$70,000 - amount spent every 13 hours by the food lobby - the result – pizza is a vegetable on school lunches 2TB vs. ½ cup
Haven’t antibiotics and vaccinations been responsible for our improvements in health ?
P R O – A C T I V E health & healing Beyond disease prevention way beyond symptomatic treatment We are so focused on disease ! Even naturopathy’s official definition is one based upon a disease focusI am a big proponent of being involved and responsible for your health & healingLet’s do what we do best in this arena western medicine can not compete
When it comes to TONICS We are so caught up in the symptom/drug paradigmthat we just aren’t able to fully embrace TONICS
You may recognize two of these mushrooms blue left – werewere-kokako - Entolomahochstetteri Fly agaric (Aminita) that someone took a nice slice out of???Estimated ~ 150,000 mushrooms only ~10% are currently known 50% of these are at least somewhat edible700 are known to contain pharmacological properties ~300 have immune and anti-tumor actionsMushrooms are, believe it or not, some of the oldest and largest organisms on this planet- Upper peninsula in Michigan - discovered Armilariagallica - covers over 30 acres - estimated weight over 100 tons - 1500 years old - they hold a “Humungus Fungus Festival”Another found to cover more than 20,000 acres (over 8,000 hectares)
There are obviously many general similarities among the mushroomsVirtually all that we have boost immune support cardiovascular in some way anti-oxidantLower blood sugar nutritionally rich Chelators
TONICS are fundamentally about Radiant HealthVitality Balance Harmonize Functionality Nourish Holistic Strengthen RADIANCE
Life is a complex
Take for instance Aging Many different theories of aging
Take for instance Aging Many different theories of aging
YOU WERE RIGHT!
Said to nourish and calm the ShenCalms and nourishes the CNS emotional disturbances
Over 5000 years ago wounded by an arrow escaped to higher altitude only to die carried 2 mushrooms: tinder and medicine one closely related to Chaga nicknamed cinder conk
Used traditionally for stomach related disorders cancers pain reliever tuberculosisAINU northern islands of Japan – smoked it in religious ceremonies - passed around the circle – like a peace pipe - called “eating the smoke”tCM - smooth the Qi strengthen the mind & Shen
Grows from Hokkaido across Siberia to the Baltic northern climes in the US looks like burnt charcoalBitter taste somewhat like coffee Traditionally used as a tea traditional use vs research ? !
Again goes well beyond just immune support
Gastric - up-regulated pro-apoptotic proteins down-regulated anti-apoptotic proteins adenocarcinoma - malignant epithelial cancer originating in glands melanoma - inhibited proliferation - induced differentiation - induced apoptosisSarcomas -- may effect gene(s) - leading to regression - induced apoptosis
Constitutional strengthener MY TAKE
Women’s Island Knot dark brown to black hoof shapedTraditional uses : improve blood circulation - enhance detoxification - hepato-protective- allergies - diabetes - Gi hemorrhage diarrhea cancers
Study of top 20Working with Dr Sliva Cancer Research Lab Methodist Research Center Indianapolis
Dose dependent suppressed colony formation
As with your Immune System, your brain is very complicated & interconnected 4 Trillion connections another example of where a holistic and tonic approach makes the most sense~ 100 million neurons ~ Each neuron has ~ 40,000 connections9 times more glial cells glial used to be ignored as structural support now much more they may actually do the thinking - creativity,… the glial cells communicate by wave actionMore neuron connections than stars in universe
HSV 1 found in 90% of plaqueBrain’s protection - blood brain barrier - glial cells
We are going to focus on AD 1797 - dementia first coined 1906 - Dr. Alzheimer described a patient by 1907 it was called “alzheimer’sThe more gray matter that dies the harder to come backPREVENTION
Incidence, Cost of Care, and Federal Research Funding You don’t even need to see the numbersNotice purple line = # of Americans with AD Next, take a look at yellow bar trend = cost of treating them NOTICE a similarity ?Now look at the teeny tiny red bars across the bottom… notice a trend difference?
Most effects Cerebral Cortex visual & spatial info Basal Forebrain HippocampusNormal Aging memory loss likely due to way neurons communicate neurofibrillary tangles do they or do they not “cause” AD? They exist in virtually every older brain.Sulcusgroove in brain surfaceGyrus ridge of brain cortex
Problem for Allopathy is they do not know the causeOnly address they symptoms
Just like with aging We need to know what alzheimer’s disease is~ 100 known causes of dementia incl: AD, multiple strokes, brain infections, severe thyroid deficiency, brain injury
AD is NOT forgetting where you put your keys
AD is NOT forgetting where you put your keys
AD is NOT forgetting where you put your keys
It’s the loss of so much of what we take for grantedMindfulness ??? M
Endocrine Blood Sugar InsulinMay be one reason these natural remedies with many constituents and many actions are of such benefit
According to the dictionary and current medical science - NO
Qi tonic Whole body tonic Digestive tonic ConstipationtCM: invigorate the Spleen and Nourish the stomach GET excited about QI Tonic ! ! !
NGF: induces neuronal differentiation (nerve identity) promote survival of neurons promote regeneration while decreasing neuro-degneration
Stimulated the fueling of macrophageLAB STUDY -- Anti-microbial - demonstrated anti-MRSA activity - confirmed by clinical test in hospital Ulcers - gastricCancer stomach, esophageal, skin liver, lung, cervical cell line HeLa Henrietta Lacks your cells don’t belong to youAtrophic wasting deterioration hiv-1 -- study - polyneuropathy
Numerous studies on NGF Neuronal cell death Oxidative or Endoplasmic Reticulum Stress 4. 3 different fractionsMyelin - supports protects and feeds the axon STUDY: LM -- process began earlier and at a higher rateNATURE’S GIFT HOLISTIC BY NATURE
50 to 80 year olds women & men mild cognitive impairment tested for 2 weeks randomized 2 - 15 people groupsLM - 4 x 250 mg tablets - 3 times a day tested 4, 8, 12, & 16 weeks improved cognitive function scores also 4 weeks after LM supplementation finished -- scores declined
No change in this case may actually be a positive result
81 year old woman, borderline dementia, hospitalized 4 times since 2002 Hospitalized at a psychiatric facility depression no marked improvement so dischargedLetter Pick Up Exam BEFORE more than 10 AFTER 2 or less
81 year old woman, borderline dementia, hospitalized 4 times since 2002 Hospitalized at a psychiatric facility depression no marked improvement so dischargedLetter Pick Up Exam BEFORE more than 10 AFTER 2 or less
Research shows 29 different molecular targets that Turmeric has on cancerAnd amazingly this is now incomplete
“…prolong the years of life without aging…”
The mushroom I want to start out with is or was our namesake
Recovery - health and treatmentFunctionality -- increase antigen presentation by dendritic cellsEndocrine - hormonesSYNERGY - whole Grifron Maitake and D-fraction
Mushrooms are about much much more than disease treatment -- RH going to quickly discuss 3 powerful RH tonics -- that are transformative remediesTONICS are fundamentally about Radiant HealthVitality Balance Harmonize Functionality Nourish Holistic Strengthen RADIANCE