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Ancient Wisdom
Modern Medicine
   by Mark J Kaylor
Health Expenditures of Nations
 2,000,000+
 284,000
 3rd
 13th
 48th
 40-60%
 $70,000
Mortality Rates
How do we best approach this?




Linear - One directional   Tonic  Systemic  Holistic
Mushrooms, not what you think
Complexity of the Aging Process
Cordyceps sinensis




 Dong chong xia cao
  “Winter worm, summer grass”
The Tale of a
      “Yak-odisiac”
• Yak brought to higher
  grounds in the Spring would
  selectively graze in the new
  grass.
• Once the ate whatever it
  was they were looking for
  they became “friskier”.
• Turns out they were eating
  the Cordyceps.
• Word travelled to the
  Imperial Court
• Thus the fame of this
  “Yakodisiac” came to be.
Cordyceps Grown by Fermentation
Cordyceps’ Traditional Uses

•    Yang Qi tonic
•    Anti-aging
•    Enriches the Kidneys (Jing) & protects the Lungs
     (Qi)
•    Dissolves phlegm
•    Heart and cardiovascular tonic
•    Enhance depressed immune function
•    Calm over active immune system
•    Sexual function restorative
Cordyceps - Rejuvenating Tonic

• Energy, Endurance,    • Lowers blood pressure
  Sports, Recovery      • Increases SOD
• Anti-oxidant          • Prevents atherosclerosis
• Liver support,        • Aides weight loss
      esp. hepatitis    • Improved sleep quality
• Anti-inflammatory     • Increased oxygen uptake &
• Lowers cholesterol      efficiency
• Respiratory support   • MAO inhibitor
• Restores adrenals
Cordyceps’ – Traditional Kidney Tonic
Cordyceps’ – Traditional Heart Tonic




Cordyceps’ Traditional Longevity Tonic
Energy, Rejuvenation, & Vitality
Reishi-Ganoderma lucidum
Ling zhi (Spirit Plant)
Mushroom of Immortality




    “…over a long period of
 time, agility of the body will
not cease, and the years are
  lengthened to those of the
      Immortal Fairies.”
Reishi & TCM


   • A traditional tonic to nourish,
      tonify and supplement the
      whole body

   • Strengthens the lungs, protects
      and stimulates the liver and
      helps the body adapt to stress

   • Removes toxins and disperses
      accumulation
Super tonic
“Tonic for the 21st century”
Reishi & Shen
Balance
Chaga - Inonotus obliquus
Chaga - Kabanoanatake
Wildcrafted Siberian Chaga
Chaga’s Diverse Benefits
Specific cancers tested with Chaga

• Human colon carcinoma
• Human gastric carcinoma
• Human breast adenocarcinoma
• Human hepato-cellular
  carcinoma
• Human HeLa cervical
  carcinoma
• Murine melanoma
• Human lung carcinoma
• Sarcomas
Chaga’s is Really All About
New to the West - Meshima


             • Phellinus linteus
             • Japanese call it
               “Meshimakobu”
             •   Grows on Mulberry, Elm
                 and Willows
             • Thousands of years of
               use in traditional
               medicine
             • Nutrient-dense
Meshima’s Diverse Benefits
Immune Actions of Phellinus linteus


• Top immune enhancer out of ~20 medicinal mushrooms
• Study: 500 mg for 30 days
   – Increased wbc ~11-81%
• Activates B cells
• Stimulates T lymphocytes
• Activates macrophage
• Orally effective
Meshima’s Effects on
Breast cancer Growth
4,000,000,000,000
Brain Vulnerability

       •   Wear-and-tear
       •   Physical damage
       •   Sustained emotional stress
       •   Long term free radical damage
       •   Nutritional imbalances
       •   Lack of exercise
       •   Pesticides
       •   Pollution
       •   Herpes simplex virus 1
Alzheimer’s Disease Projections
Change in Number of Deaths
        2000 – 2008
Damage Caused by Amyloid Beta
Problem with Diagnosis &
               Treatment
1) Currently all medicine can do is maybe slow
   progression
2) AD develops over a long time period with no signs or
   symptoms
3) With too late of a diagnosis, neurons may be dead and
   circuits may be destroyed
4) Almost impossible at this point to restore
5) PREVENT PREVENT PREVENT
What is alzheimer’s disease?

– memory loss
– language deterioration
– impaired ability to manipulate visual information
– poor judgment
– confusion
– restlessness
– mood swings


 Eventually leads to loss of cognition, personality and
                        function
So what kind of a disease is
           alzheimer’s?
 Brain
 Central Nervous System


                     What about?
   Inflammatory
   Immune
   Cardiovascular
   Free Radical
   Endocrine
Is there hope?




Encarta World English Dictionary:
  “senile dementia - a form of brain
  disorder marked by progressive
  and irreversible mental
  deterioration, memory loss and
  disorientation…”
Lion’s Mane




Yamabushitake, Hou tou gu (Monkey’s Head), Bear’s Head, pom pom
NGF and the Brain
Lion’s Mane’s Actions

• Anti-tumor                  • hiv-1 reverse transcriptase
• Immuno-modulating             activity
• Cell growth regulating      • Cholesterol lowering
• Macrophage activating       • Blood thinning
• Lymphocyte activating       • Anti-oxidant
• Anti-proliferative          • Blood sugar lowering
• Anti-microbial              • Anti-ulcer
• Toxic to cancer cells       • Benefits atrophic gastritis
• Inhibiting cancer dna/rna   • Anti-MRSA
• Improves sleep apnea        • Reduces depression &
                                anxiety
Amyloban 3399™



Contains Standardized Extracts of:
• Hericenones
   ► Stimulate production of Nerve Growth Factor
• Amyloban
   ► May prevent death of nerve cells caused by amyloid
     beta peptides.
   ► Patented (Japanese Patent # 3943399)
Lion’s Mane Nerve Support


• Induction of NGF
• Inhibition of the cytotoxicity of
  β-amyloid peptide
• Protection against neuronal cell
  death
• Stimulates myelination
• Anti-oxidant properties
• Hypoglycemic effects
• Immune enhancement
Effects of Lion’s Mane
on Nerve Cell Protection


              • Looked at ER stress
                induced neuronal cell
                death
              • Effectively protected cells
                from death
              Note: the crude extract,
              Amyloban, appeared more
              effective than purified DLPE
Lion’s Mane Clinical Study




• Rehabilitative hospital, Japan; elderly with degenerative diseases
• 6 of 7 dementia Patients improved perceptual capacities
• Marked improvements in patients evaluated by Functional Independence
Measure
• Appears to cross blood brain barrier
• Two other studies-retarded progression improved cognition
Double-blind Placebo-Controlled
     Yamabushitake Study
Lion’s Mane for Cognitive
            Impairment

• 18 patients with mild to moderate impairment
• 1.5 grams of Lion’s Mane, 2x a day
• Results:
   – 9 of 18 saw improvement
   – 7 of 18 saw no change *
   – 2 of 18 got worse
Case Report on Amyloban

      Before
• Anxious, hostile,
  impatient
• 29 dementia score
• 4 years ago, couldn’t
  name 4 vegetables
• Couldn’t cook
• “Scary” dreams
• Restless & uneasy
• Couldn’t do simple math
Case Report on Amyloban

      After
• Even temperament
• Normal score
• Can name as many as you
  want
• Cooking
• Dreams of teaching dance
• Calm & comfortable
• Now she can
“The Little Root That Could”
Turmeric Benefits

    Abscess, Adenoma, Adenosis, Allergy, Alzheimer’s, Amenorrhea, Anorexia, Arthrosis, Asthma,
    Atherosclerosis, Athlete’s foot, Bacillus, Bacteria, Bite, Bleeding, Boil, Bowen’s disease, Bronchosis,
    Bruise, Bursitis, Cancer, Cancer – abdomen, Cancer – bladder, Cancer – breast, Cancer cervix,
    Cancer– colon, Cancer – duodenum, Cancer – esophagus, Cancer – joint, Cancer – liver, Cancer –
    mouth, Cancer – skin, Cancer – stomach, Cancer – uterus, Cardiopathy, Cataract, Catarrh, Chest ache,
    Childbirth, Cholecystosis, Circulosis, Cold, Colic, Coma, Congestion, Conjuctivosis, Constipation,
    Coryza, Cramp, Cystosis, Dermatosis, Diabetes, Diarrhea, Dropsy, Duodenosis, Dysgeusia,
    Dysmenorrhea, Dyspepsia, Dysuria, Eczemia, Edema, Elephantiasis, Enterosis, Epilepsy, Epistaxis,
    Esophagosis, Fever, Fibrosis, Fungus, Gallstone, Gastrosis, Gonorrhea, Gray hair, Headache,
    Hematemesis, Hematuria, Hemorroid, Hepatosis, High blood pressure, High cholesterol, High
    triglycerides, Hyper- lipidemia, Hysteria, Immunodepression, Infection, Inflammation, Itch, Jaundice,
    Laryngosis, Leprosy, Leukemia, Leishmania, Leukoderma, Leukoplakia, Lymphoma, Malaria, Mania,
    Morning sickness, Mucososis, Mycosis, Nematode, Nephrosis, Nervousness, Ophthalmia,
    Osteoarthrosis, Ozena, Pain, Parasite, Polyp, Psoriasis, Puerperium, Radiation injury, Restenosis,
    Rheumatism, Rhinosis, Ring worm, Scabies, Small pox, Sore, Sore throat, Sprain, Stone,
    Staphylococcus, Stroke, Swelling, Syphilis, Trauma, Ulcer, Uveosis, Vertigo, Vomiting, Wart, Water
    retention, Whitelow, Worm, Wound, Yeast (Duke 2003).
Berries, A True Superfood

• Anti-inflammatory      •   Improves memory
• Anti-oxidant, esp.     •   Prevents brain oxidation
  cardiovascular         •   Supports a healthy brain
• Immune functions       •   Anti-bacterial
• Urinary tract health   •   Decrease cancer risk
                         •   Anti-mutagenic
                         •   Increase tumor
                             suppressor genes
                         •   Inhibit metastasis
                         •   Lowers LDL
                         •   Vision health
                         •   Oral health
Schizandra - Wu Wei Zi


            • Supports all 3 Treasures
            • Builds primary life-energy
            • Rejuvenates Qi & Jing
            • Supports & protects liver
            • Improves vision
            • Youth preserving
            • Purifies the blood
            • Adaptogen & antioxidant
Schizandra, Traditional Tonic

           Use for 100 days in a row:
           •   purify blood
           • sharpen mind
           •   improve memory
           •   rejuvenate Qi
           •   cause skin to become radiantly
               beautiful
The Story of Yang Guifei


  One of China 4 most
   beautiful women

  Said to be so beautiful
   that flowers would bow
   before her beauty

  One of her beauty
   secrets: Tremella

  Tremella is a traditinal
   Yin tonic
Maitake’s (Holistic) Immune Benefits

Direct                       Supportive

•   Prevent mutation         •   Anti-oxidant
•   Immune stimulation       •   Anti-inflammatory
•   Increase phagocytosis    •   Lowers blood sugar
•   Activate NK cells        •   Lowers insulin levels
•   Improved functionality   •   Liver protecting
•   Apoptosis                •   Liver detoxifying
•   Potentiate therapy       •   Endocrine balancing
•   Recovery                 •   Inhibit platelet
•   Targeting                    aggregation
•   Metastasis inhibition
Chinese or Korean Ginseng




        Panax = panacea
Tonic Uses of Ginseng

• Strengthen the whole body
• Improve overall functioning
• Normalizing action on the body
• Restorative & rejuvenating
• “Tonic” to central nervous system, digestive &
   respiratory tract
• Ultimate adaptogen
•Builds and supports all 3 Treasures
   Qi, Shen and Jing
• “Closest thing to a panacea that we have”
He shou wu


   • Li Ching Yuen 256 yrs. Old
   • Yin Jing tonic
   • Increases SOD activity


   • 50 yr old - grey hair black
   • 100 yr old - youthfulness
   • 300 yr old - immortality
He Shou Wu


• Traditional “youthfulness” tonic (Yin Jing)
• Supplements Qi & Blood
• Invigorates Liver & Kidneys
• Anti-bacterial, antioxidant, anti-inflammatory
• Strengthen lower back, knees & connective tissues
• Strengthens & supports red blood cells
The New Pharmacology: “Farmacolgy”
Thank you
Questions ?



    Comments ?


Feedback ?
mjk@mushroomwisdom.com
Pre-Clinical Studies

3 studies tested Lion’s Mane:

① 7 patients with dementia were given LM powder, showed
  improvement in daily living activity
② 15 patients with dementia showed similar improvement
  with LM tablets.
③ 7 patients with Alzheimer’s showed improvement in their
  peripheral symptoms with LM tablets (wandering,
  aggressiveness).
Effects of Cs-4 on Senescence

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Ancient Wisdom Modern Medicine

  • 1.
  • 3.
  • 4.
  • 5.
  • 7.  2,000,000+  284,000  3rd  13th  48th  40-60%  $70,000
  • 9. How do we best approach this? Linear - One directional Tonic  Systemic  Holistic
  • 10.
  • 11. Mushrooms, not what you think
  • 12.
  • 13.
  • 14.
  • 15. Complexity of the Aging Process
  • 16.
  • 17.
  • 18. Cordyceps sinensis Dong chong xia cao “Winter worm, summer grass”
  • 19. The Tale of a “Yak-odisiac” • Yak brought to higher grounds in the Spring would selectively graze in the new grass. • Once the ate whatever it was they were looking for they became “friskier”. • Turns out they were eating the Cordyceps. • Word travelled to the Imperial Court • Thus the fame of this “Yakodisiac” came to be.
  • 20. Cordyceps Grown by Fermentation
  • 21. Cordyceps’ Traditional Uses • Yang Qi tonic • Anti-aging • Enriches the Kidneys (Jing) & protects the Lungs (Qi) • Dissolves phlegm • Heart and cardiovascular tonic • Enhance depressed immune function • Calm over active immune system • Sexual function restorative
  • 22. Cordyceps - Rejuvenating Tonic • Energy, Endurance, • Lowers blood pressure Sports, Recovery • Increases SOD • Anti-oxidant • Prevents atherosclerosis • Liver support, • Aides weight loss esp. hepatitis • Improved sleep quality • Anti-inflammatory • Increased oxygen uptake & • Lowers cholesterol efficiency • Respiratory support • MAO inhibitor • Restores adrenals
  • 24. Cordyceps’ – Traditional Heart Tonic Cordyceps’ Traditional Longevity Tonic
  • 26.
  • 27. Reishi-Ganoderma lucidum Ling zhi (Spirit Plant) Mushroom of Immortality “…over a long period of time, agility of the body will not cease, and the years are lengthened to those of the Immortal Fairies.”
  • 28. Reishi & TCM • A traditional tonic to nourish, tonify and supplement the whole body • Strengthens the lungs, protects and stimulates the liver and helps the body adapt to stress • Removes toxins and disperses accumulation
  • 30. “Tonic for the 21st century”
  • 31.
  • 34. Chaga - Inonotus obliquus
  • 38. Specific cancers tested with Chaga • Human colon carcinoma • Human gastric carcinoma • Human breast adenocarcinoma • Human hepato-cellular carcinoma • Human HeLa cervical carcinoma • Murine melanoma • Human lung carcinoma • Sarcomas
  • 39. Chaga’s is Really All About
  • 40. New to the West - Meshima • Phellinus linteus • Japanese call it “Meshimakobu” • Grows on Mulberry, Elm and Willows • Thousands of years of use in traditional medicine • Nutrient-dense
  • 42. Immune Actions of Phellinus linteus • Top immune enhancer out of ~20 medicinal mushrooms • Study: 500 mg for 30 days – Increased wbc ~11-81% • Activates B cells • Stimulates T lymphocytes • Activates macrophage • Orally effective
  • 45. Brain Vulnerability • Wear-and-tear • Physical damage • Sustained emotional stress • Long term free radical damage • Nutritional imbalances • Lack of exercise • Pesticides • Pollution • Herpes simplex virus 1
  • 46.
  • 48. Change in Number of Deaths 2000 – 2008
  • 49.
  • 50. Damage Caused by Amyloid Beta
  • 51. Problem with Diagnosis & Treatment 1) Currently all medicine can do is maybe slow progression 2) AD develops over a long time period with no signs or symptoms 3) With too late of a diagnosis, neurons may be dead and circuits may be destroyed 4) Almost impossible at this point to restore 5) PREVENT PREVENT PREVENT
  • 52. What is alzheimer’s disease? – memory loss – language deterioration – impaired ability to manipulate visual information – poor judgment – confusion – restlessness – mood swings Eventually leads to loss of cognition, personality and function
  • 53.
  • 54.
  • 55.
  • 56.
  • 57. So what kind of a disease is alzheimer’s?  Brain  Central Nervous System What about?  Inflammatory  Immune  Cardiovascular  Free Radical  Endocrine
  • 58. Is there hope? Encarta World English Dictionary: “senile dementia - a form of brain disorder marked by progressive and irreversible mental deterioration, memory loss and disorientation…”
  • 59.
  • 60. Lion’s Mane Yamabushitake, Hou tou gu (Monkey’s Head), Bear’s Head, pom pom
  • 61. NGF and the Brain
  • 62. Lion’s Mane’s Actions • Anti-tumor • hiv-1 reverse transcriptase • Immuno-modulating activity • Cell growth regulating • Cholesterol lowering • Macrophage activating • Blood thinning • Lymphocyte activating • Anti-oxidant • Anti-proliferative • Blood sugar lowering • Anti-microbial • Anti-ulcer • Toxic to cancer cells • Benefits atrophic gastritis • Inhibiting cancer dna/rna • Anti-MRSA • Improves sleep apnea • Reduces depression & anxiety
  • 63. Amyloban 3399™ Contains Standardized Extracts of: • Hericenones ► Stimulate production of Nerve Growth Factor • Amyloban ► May prevent death of nerve cells caused by amyloid beta peptides. ► Patented (Japanese Patent # 3943399)
  • 64. Lion’s Mane Nerve Support • Induction of NGF • Inhibition of the cytotoxicity of β-amyloid peptide • Protection against neuronal cell death • Stimulates myelination • Anti-oxidant properties • Hypoglycemic effects • Immune enhancement
  • 65. Effects of Lion’s Mane on Nerve Cell Protection • Looked at ER stress induced neuronal cell death • Effectively protected cells from death Note: the crude extract, Amyloban, appeared more effective than purified DLPE
  • 66. Lion’s Mane Clinical Study • Rehabilitative hospital, Japan; elderly with degenerative diseases • 6 of 7 dementia Patients improved perceptual capacities • Marked improvements in patients evaluated by Functional Independence Measure • Appears to cross blood brain barrier • Two other studies-retarded progression improved cognition
  • 67. Double-blind Placebo-Controlled Yamabushitake Study
  • 68. Lion’s Mane for Cognitive Impairment • 18 patients with mild to moderate impairment • 1.5 grams of Lion’s Mane, 2x a day • Results: – 9 of 18 saw improvement – 7 of 18 saw no change * – 2 of 18 got worse
  • 69. Case Report on Amyloban Before • Anxious, hostile, impatient • 29 dementia score • 4 years ago, couldn’t name 4 vegetables • Couldn’t cook • “Scary” dreams • Restless & uneasy • Couldn’t do simple math
  • 70. Case Report on Amyloban After • Even temperament • Normal score • Can name as many as you want • Cooking • Dreams of teaching dance • Calm & comfortable • Now she can
  • 71. “The Little Root That Could”
  • 72. Turmeric Benefits  Abscess, Adenoma, Adenosis, Allergy, Alzheimer’s, Amenorrhea, Anorexia, Arthrosis, Asthma, Atherosclerosis, Athlete’s foot, Bacillus, Bacteria, Bite, Bleeding, Boil, Bowen’s disease, Bronchosis, Bruise, Bursitis, Cancer, Cancer – abdomen, Cancer – bladder, Cancer – breast, Cancer cervix, Cancer– colon, Cancer – duodenum, Cancer – esophagus, Cancer – joint, Cancer – liver, Cancer – mouth, Cancer – skin, Cancer – stomach, Cancer – uterus, Cardiopathy, Cataract, Catarrh, Chest ache, Childbirth, Cholecystosis, Circulosis, Cold, Colic, Coma, Congestion, Conjuctivosis, Constipation, Coryza, Cramp, Cystosis, Dermatosis, Diabetes, Diarrhea, Dropsy, Duodenosis, Dysgeusia, Dysmenorrhea, Dyspepsia, Dysuria, Eczemia, Edema, Elephantiasis, Enterosis, Epilepsy, Epistaxis, Esophagosis, Fever, Fibrosis, Fungus, Gallstone, Gastrosis, Gonorrhea, Gray hair, Headache, Hematemesis, Hematuria, Hemorroid, Hepatosis, High blood pressure, High cholesterol, High triglycerides, Hyper- lipidemia, Hysteria, Immunodepression, Infection, Inflammation, Itch, Jaundice, Laryngosis, Leprosy, Leukemia, Leishmania, Leukoderma, Leukoplakia, Lymphoma, Malaria, Mania, Morning sickness, Mucososis, Mycosis, Nematode, Nephrosis, Nervousness, Ophthalmia, Osteoarthrosis, Ozena, Pain, Parasite, Polyp, Psoriasis, Puerperium, Radiation injury, Restenosis, Rheumatism, Rhinosis, Ring worm, Scabies, Small pox, Sore, Sore throat, Sprain, Stone, Staphylococcus, Stroke, Swelling, Syphilis, Trauma, Ulcer, Uveosis, Vertigo, Vomiting, Wart, Water retention, Whitelow, Worm, Wound, Yeast (Duke 2003).
  • 73. Berries, A True Superfood • Anti-inflammatory • Improves memory • Anti-oxidant, esp. • Prevents brain oxidation cardiovascular • Supports a healthy brain • Immune functions • Anti-bacterial • Urinary tract health • Decrease cancer risk • Anti-mutagenic • Increase tumor suppressor genes • Inhibit metastasis • Lowers LDL • Vision health • Oral health
  • 74. Schizandra - Wu Wei Zi • Supports all 3 Treasures • Builds primary life-energy • Rejuvenates Qi & Jing • Supports & protects liver • Improves vision • Youth preserving • Purifies the blood • Adaptogen & antioxidant
  • 75. Schizandra, Traditional Tonic Use for 100 days in a row: • purify blood • sharpen mind • improve memory • rejuvenate Qi • cause skin to become radiantly beautiful
  • 76. The Story of Yang Guifei  One of China 4 most beautiful women  Said to be so beautiful that flowers would bow before her beauty  One of her beauty secrets: Tremella  Tremella is a traditinal Yin tonic
  • 77.
  • 78. Maitake’s (Holistic) Immune Benefits Direct Supportive • Prevent mutation • Anti-oxidant • Immune stimulation • Anti-inflammatory • Increase phagocytosis • Lowers blood sugar • Activate NK cells • Lowers insulin levels • Improved functionality • Liver protecting • Apoptosis • Liver detoxifying • Potentiate therapy • Endocrine balancing • Recovery • Inhibit platelet • Targeting aggregation • Metastasis inhibition
  • 79.
  • 80. Chinese or Korean Ginseng Panax = panacea
  • 81. Tonic Uses of Ginseng • Strengthen the whole body • Improve overall functioning • Normalizing action on the body • Restorative & rejuvenating • “Tonic” to central nervous system, digestive & respiratory tract • Ultimate adaptogen •Builds and supports all 3 Treasures Qi, Shen and Jing • “Closest thing to a panacea that we have”
  • 82. He shou wu • Li Ching Yuen 256 yrs. Old • Yin Jing tonic • Increases SOD activity • 50 yr old - grey hair black • 100 yr old - youthfulness • 300 yr old - immortality
  • 83. He Shou Wu • Traditional “youthfulness” tonic (Yin Jing) • Supplements Qi & Blood • Invigorates Liver & Kidneys • Anti-bacterial, antioxidant, anti-inflammatory • Strengthen lower back, knees & connective tissues • Strengthens & supports red blood cells
  • 84. The New Pharmacology: “Farmacolgy”
  • 86. Questions ? Comments ? Feedback ?
  • 88. Pre-Clinical Studies 3 studies tested Lion’s Mane: ① 7 patients with dementia were given LM powder, showed improvement in daily living activity ② 15 patients with dementia showed similar improvement with LM tablets. ③ 7 patients with Alzheimer’s showed improvement in their peripheral symptoms with LM tablets (wandering, aggressiveness).
  • 89. Effects of Cs-4 on Senescence

Editor's Notes

  1. This is going to be something like a tasting to peak your interestInterestof mine is to track traditional uses of remedies and compare more recent “scientific” research with it.
  2. Today I am going to be talking about: #1 - A new “old” approach to health& healing #2 - And possibly a new goalNot just elimination of symptoms Or even just preventionWe hear a lot about “healthcare” in a system devoted to symptom and disease care a disease management system
  3. Dose dependent suppressed colony formation
  4. Mushrooms and fungi’s benefits are broad and promising, esp. for the world today Fungi are the Great Recyclers for the planetMyco-remediation comparison study bound better than traditional remediation techniquesRadiation - chelator, radio-active sites, protects body
  5. 2,000,000 # of serious adverse drug side effects (year 2000) 284,000 - iatrogenic deaths - nice way of saying medicine caused - hospitals 3rd – leading cause of death - ahead of accidents, auto deaths, diabetes,…13th - infant mortality rate among “modern” or “advanced” nations - Out of 16 48th - rank of U.S. lifespan 40-60% - projected obesity rate for 2030 - BMI of 40% or higher$70,000 - amount spent every 13 hours by the food lobby - the result – pizza is a vegetable on school lunches 2TB vs. ½ cup
  6. Haven’t antibiotics and vaccinations been responsible for our improvements in health ?
  7. P R O – A C T I V E health & healing Beyond disease prevention way beyond symptomatic treatment We are so focused on disease ! Even naturopathy’s official definition is one based upon a disease focusI am a big proponent of being involved and responsible for your health & healingLet’s do what we do best in this arena western medicine can not compete
  8. When it comes to TONICS We are so caught up in the symptom/drug paradigmthat we just aren’t able to fully embrace TONICS
  9. You may recognize two of these mushrooms blue left – werewere-kokako - Entolomahochstetteri Fly agaric (Aminita) that someone took a nice slice out of???Estimated ~ 150,000 mushrooms only ~10% are currently known 50% of these are at least somewhat edible700 are known to contain pharmacological properties ~300 have immune and anti-tumor actionsMushrooms are, believe it or not, some of the oldest and largest organisms on this planet- Upper peninsula in Michigan - discovered Armilariagallica - covers over 30 acres - estimated weight over 100 tons - 1500 years old - they hold a “Humungus Fungus Festival”Another found to cover more than 20,000 acres (over 8,000 hectares)
  10. There are obviously many general similarities among the mushroomsVirtually all that we have boost immune support cardiovascular in some way anti-oxidantLower blood sugar nutritionally rich Chelators
  11. TONICS are fundamentally about Radiant HealthVitality Balance Harmonize Functionality Nourish Holistic Strengthen RADIANCE
  12. Life is a complex
  13. Take for instance Aging Many different theories of aging
  14. Take for instance Aging Many different theories of aging
  15. YOU WERE RIGHT!
  16. Said to nourish and calm the ShenCalms and nourishes the CNS emotional disturbances
  17. Over 5000 years ago wounded by an arrow escaped to higher altitude only to die carried 2 mushrooms: tinder and medicine one closely related to Chaga nicknamed cinder conk
  18. Used traditionally for stomach related disorders cancers pain reliever tuberculosisAINU northern islands of Japan – smoked it in religious ceremonies - passed around the circle – like a peace pipe - called “eating the smoke”tCM - smooth the Qi strengthen the mind & Shen
  19. Grows from Hokkaido across Siberia to the Baltic northern climes in the US looks like burnt charcoalBitter taste somewhat like coffee Traditionally used as a tea traditional use vs research ? !
  20. Again goes well beyond just immune support
  21. Gastric - up-regulated pro-apoptotic proteins down-regulated anti-apoptotic proteins adenocarcinoma - malignant epithelial cancer originating in glands melanoma - inhibited proliferation - induced differentiation - induced apoptosisSarcomas -- may effect gene(s) - leading to regression - induced apoptosis
  22. Constitutional strengthener MY TAKE
  23. Women’s Island Knot dark brown to black hoof shapedTraditional uses : improve blood circulation - enhance detoxification - hepato-protective- allergies - diabetes - Gi hemorrhage diarrhea cancers
  24. Study of top 20Working with Dr Sliva Cancer Research Lab Methodist Research Center Indianapolis
  25. Dose dependent suppressed colony formation
  26. As with your Immune System, your brain is very complicated & interconnected 4 Trillion connections another example of where a holistic and tonic approach makes the most sense~ 100 million neurons ~ Each neuron has ~ 40,000 connections9 times more glial cells glial used to be ignored as structural support now much more they may actually do the thinking - creativity,… the glial cells communicate by wave actionMore neuron connections than stars in universe
  27. HSV 1 found in 90% of plaqueBrain’s protection - blood brain barrier - glial cells
  28. We are going to focus on AD 1797 - dementia first coined 1906 - Dr. Alzheimer described a patient by 1907 it was called “alzheimer’sThe more gray matter that dies the harder to come backPREVENTION
  29. Incidence, Cost of Care, and Federal Research Funding You don’t even need to see the numbersNotice purple line = # of Americans with AD Next, take a look at yellow bar trend = cost of treating them NOTICE a similarity ?Now look at the teeny tiny red bars across the bottom… notice a trend difference?
  30. Most effects Cerebral Cortex visual & spatial info Basal Forebrain HippocampusNormal Aging memory loss likely due to way neurons communicate neurofibrillary tangles do they or do they not “cause” AD? They exist in virtually every older brain.Sulcusgroove in brain surfaceGyrus ridge of brain cortex
  31. Problem for Allopathy is they do not know the causeOnly address they symptoms
  32. Just like with aging We need to know what alzheimer’s disease is~ 100 known causes of dementia incl: AD, multiple strokes, brain infections, severe thyroid deficiency, brain injury
  33. AD is NOT forgetting where you put your keys
  34. AD is NOT forgetting where you put your keys
  35. AD is NOT forgetting where you put your keys
  36. It’s the loss of so much of what we take for grantedMindfulness ??? M
  37. Endocrine Blood Sugar InsulinMay be one reason these natural remedies with many constituents and many actions are of such benefit
  38. According to the dictionary and current medical science - NO
  39. Qi tonic Whole body tonic Digestive tonic ConstipationtCM: invigorate the Spleen and Nourish the stomach GET excited about QI Tonic ! ! !
  40. NGF: induces neuronal differentiation (nerve identity) promote survival of neurons promote regeneration while decreasing neuro-degneration
  41. Stimulated the fueling of macrophageLAB STUDY -- Anti-microbial - demonstrated anti-MRSA activity - confirmed by clinical test in hospital Ulcers - gastricCancer stomach, esophageal, skin liver, lung, cervical cell line HeLa Henrietta Lacks your cells don’t belong to youAtrophic wasting deterioration hiv-1 -- study - polyneuropathy
  42. Numerous studies on NGF Neuronal cell death Oxidative or Endoplasmic Reticulum Stress 4. 3 different fractionsMyelin - supports protects and feeds the axon STUDY: LM -- process began earlier and at a higher rateNATURE’S GIFT HOLISTIC BY NATURE
  43. HE = Amyloban 3399 Endoplasmic RiticulumControl ~ 9 ± 5HE 10 / ~65 ± 10 100 / ~ 77 ± 6DLPE 50 / ~ 67 ± 2 150 / ~ 92 ± 2
  44. 50 to 80 year olds women & men mild cognitive impairment tested for 2 weeks randomized 2 - 15 people groupsLM - 4 x 250 mg tablets - 3 times a day tested 4, 8, 12, & 16 weeks improved cognitive function scores also 4 weeks after LM supplementation finished -- scores declined
  45. No change in this case may actually be a positive result
  46. 81 year old woman, borderline dementia, hospitalized 4 times since 2002 Hospitalized at a psychiatric facility depression no marked improvement so dischargedLetter Pick Up Exam BEFORE more than 10 AFTER 2 or less
  47. 81 year old woman, borderline dementia, hospitalized 4 times since 2002 Hospitalized at a psychiatric facility depression no marked improvement so dischargedLetter Pick Up Exam BEFORE more than 10 AFTER 2 or less
  48. Research shows 29 different molecular targets that Turmeric has on cancerAnd amazingly this is now incomplete
  49. “…prolong the years of life without aging…”
  50. The mushroom I want to start out with is or was our namesake
  51. Recovery - health and treatmentFunctionality -- increase antigen presentation by dendritic cellsEndocrine - hormonesSYNERGY - whole Grifron Maitake and D-fraction
  52. Mushrooms are about much much more than disease treatment -- RH going to quickly discuss 3 powerful RH tonics -- that are transformative remediesTONICS are fundamentally about Radiant HealthVitality Balance Harmonize Functionality Nourish Holistic Strengthen RADIANCE