A.J. Cronin's novel The Citadel follows newly qualified doctor Andrew Manson as he begins his career in 1920s Wales. Horrified by the poor conditions faced by miners, Manson dedicates himself to researching lung diseases. His work gains recognition but he later loses focus chasing wealth. Tragedy strikes as his wife is killed and Manson faces a hearing for allegedly improper conduct. However, Manson's passionate defense of his choices allows him to avoid being struck from the medical register.