The AGINFRA PLUS project received funding from the European Union's Horizon 2020 research program to accelerate user-driven innovation in e-infrastructure for food and agriculture. The three year project involves seven partners across Europe led by AGRO-KNOW IKE. It aims to develop innovative applications and workflows powered by open e-infrastructures to strengthen the AGINFRA virtual research environment for the agriculture and food domains. Three initial pilot applications will focus on agro-climatic and economic modeling, food safety risk assessment, and food security issues.