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Nikolaos C. Aggelopoulos
       BSc, MSc, PhD




     Spemannstrasse 38
      72076 Tübingen
         Germany




 Curriculum Vitae




        Page 1 of 12
Curriculum Vitae
Name:                Nikolaos C. Aggelopoulos


I. PERSONAL DATA

Date of birth:       August 20th, 1962

Nationality:         Greek

Correspondence:      Neurophysiology Department, Max-Planck-Instiut fuer
                     Biologische Kybernetik, Spemannstr. 38, 72076 Tuebingen,
                     Germany.

Awards:              a) Vasileus Pavlos National Institute Scholarship, Greece, 1980.
                     b) Award of Distinction on conference of BSc.
                     c) Max Planck Institute Fellowship, Germany 1997

Current Position:    Postdoctoral Research Associate, supported by the BMBF.

Current memberships: a) Physiological Society, UK
                    b) Hellenic Society for Neuroscience (HSN)


References:

(a) Prof Stephen A. Edgley, Department of Physiology, Development and Neuroscience,
        University of Cambridge, Downing Street, Cambridge CB2 3DY, UK. Tel: +44
        1223 333757 e-mail: sae1000@cus.cam.ac.uk

(b) PD Dr Hilmar Meissl, Max Planck Institute for Brain Research, Deutschordenstr. 46,
       60528 Frankfurt, Germany. Tel: +49 69 967 69 239 e-mail: meissl@mpih-
       frankfurt.mpg.de

(c) Prof Edmund T Rolls, formerly Department of Experimental Psychology, University
        of Oxford, now retired. Oxford Centre for Computational Neuroscience, Oxford,
        UK. e-mail: Edmund.Rolls@oxcns.org

(d) Prof Nikos K Logothetis, Max Planck Institute for Biological Cybernetics,
        Spemannstr. 21, 72076 Tuebingen, Germany, Tel: +49 7071 601651 e-mail:
        Nikos.Logothetis@tuebingen.mpg.de




                                     Page 2 of 12
II. ACADEMIC DEGREES

Year Degree University                               Country       Subject

1985 BSc      McGill University                      CANADA        Biology
1986 MSc      University of London                   UK            Neurological Science
1990 PhD      University of London                   UK            Physiology

III. UNIVERSITY EDUCATION

Time          Institution                            Country       Subject

1981/82       Lakehead University, Ontario           CANADA        Biology
1982-85       McGill University, Montreal,           CANADA        Neurobiology &
              Quebec                                               Comparative
                                                                   Physiology
1985-1986     University College,                   UK             Neurological Science
              University of London
1987-1990     King's College,                       UK               Physiology
              University of London
              PhD thesis titled: Melatonin receptors target sites in the brain.


IV. PROFESSIONAL BACKGROUND

Time          Position                               Institution

7/90-7/92     National Service                       Army (GREECE)
8/92-5/97     Postdoctoral Research Associate        Department of Anatomy
                                                     University of Cambridge, UK
5/97-5/99     Postdoctoral Fellow                    Max Planck Institute, Bad Nauheim
5/99-11/00    Postdoctoral Research Associate        Department of Anatomy,
                                                     University of Cambridge, UK
11/00-01/06   Postdoctoral Research Associate        Department of Experimental
                                                     Psychology,
                                                     University of Oxford, UK
02/06-02-/07 Research Scholar                        Psychology Department, Princeton
                                                     University, USA
06/07-present Postdoctoral Research Associate        Max Planck Institute, Tuebingen




                                      Page 3 of 12
V. TEACHING

Neurophysiology demonstrations (1987-1990) for 1st and 2nd year physiology students at
King's College London, Biomedical Sciences Division.

Neuroanatomy demonstrations (1995) for 2nd year veterinary students in neuroanatomy.

Tutorials for part Ib medical students at the University of Cambridge:
  (a) Neurobiology Ib, Emmanuel College (1994) - 12 students.
  (b) Neurobiology Ib, Sidney Sussex College (1995) - 7 students.
  (c) Neurobiology Ib, St Johns College (1996) - 15 students.

Supervision of a medical student on a summer research project funded by a Nuffield
Foundation Undergraduate Research Bursary (1994) at the University of Cambridge.
Subject: The distribution and density of specific high-affinity melatonin receptors in the
brain during development.

Supervision of a Masters student’s lab rotation on a BMBF-funded project on Responses
of neurons in the nucleus basalis to visual stimuli differing in their familiarity, category
and coherence (2011) at the Max Planck Institute for Biological Cybernetics.

Co-supervision of undergraduate and graduate students working in the lab at the
Universities of Cambridge (1993-1999) and Oxford (2003-2005).

Invigilation duties in examinations 1987-2000.

VI. FURTHER EDUCATION/ TRAINING

Staff development course in Effective Teaching, University of Cambridge, 1993

Workshop in voltage and patch clamp techniques, FENS 2000, Brighton Conference
Centre, 24 June 2000.

Practical Workshop in temperature control and recording chambers, FENS 2000,
Brighton Conference Centre, 24 June 2000.

Laboratory Animal Management and Welfare Modules 1-3, University of Oxford
Veterinary Services, November 2000

Autumn School of Cognitive Neuroscience, University of Oxford, supported by the MRC
Interdisciplinary Research Centre for Cognitive Neuroscience, McDonnell Centre for
Cognitive Neuroscience and the Guarantors of Brain, 30 September - 3 October 2002

Autumn School of Cognitive Neuroscience, University of Oxford, supported by the MRC
Interdisciplinary Research Centre for Cognitive Neuroscience, McDonnell Centre for
Cognitive Neuroscience and the Guarantors of Brain, 29 September-2 October 2003

                                        Page 4 of 12
Developments in Neural Probe Technologies and Applications VI: a satellite symposium
at the Annual Meeting of the Society for Neuroscience, New Orleans, 7 November 2003

Laboratory Animal Management and Welfare Modules 4, University of Oxford
Veterinary Services, September 2004

Autumn School of Cognitive Neuroscience, University of Oxford, supported by the MRC
Interdisciplinary Research Centre for Cognitive Neuroscience, McDonnell Centre for
Cognitive Neuroscience and the Guarantors of Brain, 28 September-1 October 2004

Laboratory Animal Management and Welfare Modules 5, University of Oxford
Veterinary Services, October 2004

Autumn School of Neuroscience, University of Oxford, supported by the MRC
Interdisciplinary Research Centre for Cognitive Neuroscience, McDonnell Centre for
Cognitive Neuroscience and the Guarantors of Brain, 26-29 September 2005

Programming Level 3: Introduction to C and Further C; Oxford University Computing
Services, 20 Oct – 30 Nov 2005

Programming Level 4: Further C; Oxford University Computing Services, 16-30
November 2005

Linux Desktop Level 2; Oxford University Computing Services, 2 – 16 November 2005

MRI certification level 1; Princeton University February-March 2006

AFNI training for fMRI analysis; Princeton University March-April 2006

Basic Matlab; University of Tuebingen October 2008




                                     Page 5 of 12
VII. GRANTS

a) University of London Central Research Fund (1989): In vitro autoradiography of
     melatonin receptors.
b) Nuffield Foundation Undergraduate Bursary (23/6/94 - 13/8/94): The distribution and
    density of specific high-affinity melatonin receptors in the brain during development.
c) Royal Society Research Grant (7/7/94 - 7/9/95): Melatonin receptors.
d) Max Planck Society Fellowship (1/5/97-30/4/99) The visual input to the
     suprachiasmatic nuclei of the rat.
e) National Institutes of Health (2001-2006):
   £215,255 to Dr D Maxwell & Dr BA Bannatyne (IBLS - Neuroscience & Biomedical
   Systems), Prof E Jankowska, Dr I Hammar, Dr S Hjorth, Dr H Bengtsson (Goteborg
   University, Sweden), Dr S Edgley & Dr N Aggelopoulos (Cambridge University):
     Spinal interneurons: 5HT-NA receptors, actions, circuits.




                                       Page 6 of 12
VIII. LIST OF PUBLICATIONS


A. Full Papers

Aggelopoulos N., Parnavelas, J.G. and Edmunds, S. (1989): Synaptogenesis in the dorsal lateral
geniculate nucleus of the rat. Anatomy and Embryology 180, 243-257.

Aggelopoulos, N.C. and Edgley, S.A. (1995): Segmental localisation of the relays mediating
crossed inhibition from group II afferents in the anaesthetized cat spinal cord. Neuroscience
Letters 185, 60-64.

Aggelopoulos, N.C., Duke, C. and Edgley, S.A. (1995): Non-uniform conduction time in the
olivocerebellar pathway in the anaesthetized cat. Journal of Physiology 486(3), 763-768.

Aggelopoulos, N.C., Burton, M.J., Clarke, R.W. and Edgley S.A. (1996): Characterization of a
descending system which enables crossed group II inhibitory reflex pathways in the cat spinal
cord. Journal of Neuroscience 16(2), 723-729.

Aggelopoulos, N.C., Bawa, P. and Edgley, S.A. (1996): Activation of midlumbar neurones by
afferents from anterior hindlimb muscles in the cat. Journal of Physiology 497(3), 795-802.

Aggelopoulos, N.C., Chakrabarty, S. and Edgley, S.A. (1997): Evoked excitability changes at the
terminals of midlumbar premotor interneurons in the cat spinal cord. Journal of Neuroscience
17(4), 1512-1518.

Aggelopoulos, N.C., Brown, S.J., Demaine C., Harris, N.G. & Jones H.C. (1998) An abnormal
distribution of melatonin receptors in the newborn rat with inherited prenatal hydrocephalus.
Neuroscience 80(3), 669-673.

Aggelopoulos, N.C. & Meissl, H. (2000) Responses of neurones of the rat suprachiasmatic
nucleus (SCN) to retinal illumination under photopic and scotopic conditions. Journal of
Physiology 523(1), 211-222

Rolls, ET, Aggelopoulos NC & Zheng F. (2002) The receptive fields of inferior temporal cortex
neurons in natural scenes. Journal of Neuroscience, 23: 339-348

Rolls, ET, Franco, L, Aggelopoulos, NC, and Reece, S (2003) Application of an information
theoretic approach to analysing the contributions of the firing rates and correlations between the
firing of neurons. Journal of Neurophysiology 89, 2810-2822.

Franco, L, Rolls, ET, Aggelopoulos, NC, Treves, A (2004) The use of decoding to analyze the
contribution to the information of the correlations between the firing of simultaneously recorded
neurons. Experimental Brain Research, 155, 370-384.

Rolls ET, Aggelopoulos NC, Franco L, Treves A (2004) Information encoding in the inferior
temporal visual cortex: contributions of the firing rates and the correlations between the firing of
neurons. Biological Cybernetics 90, 19-32.




                                           Page 7 of 12
Aggelopoulos NC, Franco L, Rolls ET (2005) Object perception in natural scenes: encoding by
inferior temporal cortex simultaneously recorded neurons. Journal of Neurophysiology 93, 1342-
1357.

Aggelopoulos N.C. and Rolls E.T (2005) Scene perception: inferior temporal cortex neurons
encode the positions of different objects in the scene. European Journal of Neuroscience 22(11),
2903-16

Edgley SA and Aggelopoulos NC (2005) Short latency crossed inhibitory reflex actions evoked
from cutaneous afferents. Experimental Brain Research 171(4), 541-50

Rolls ET, Franco L, Aggelopoulos NC, Jerez JM. (2006) Information in the first spike, the order
of spikes, and the number of spikes provided by neurons in the inferior temporal visual cortex.
Vision Research 46(25), 4193-205

Franco L , Rolls ET , Aggelopoulos NC and Jerez JM (2007) Neuronal selectivity, population
sparseness, and ergodicity in the inferior temporal visual cortex. Biological Cybernetics 96(6),
547.

Aggelopoulos NC, Chakrabarty S and Edgley SA (2008) Presynaptic control of transmission
through group II muscle afferents in the midlumbar and sacral segments of the spinal cord is
independent of corticospinal control. Experimental Brain Research 187(1), 61-70.

Aggelopoulos NC, Liebe S, Logothetis NK & Rainer G: (2011) Cholinergic control of visual
categorization in macaques. Frontiers in Behavioral Neuroscience 5(73):1-10

B. Book chapters

Aggelopoulos, N. and Demaine, C. (1991) The development of regional distribution of melatonin
receptors in the brain of the rat studied by quantitative autoradiography. In Advances in Pineal
Research, Vol. 5. Vith Colloquium of the European Pineal Study Group, Guildford, England,
UK., Sep. 2-7 1990. Ed. ARENDT, J. & PEVET, P., pp.201-204. John Libbey & Co. Ltd,
London, England, UK; Montrouge, France. ISBN 0-86196-270-2

Aggelopoulos, N.C., Clarke, R.W. and Edgley S.A. (1995): Descending control of a crossed
spinal reflex by serotonin. In Alpha and Gamma Motor Systems, ed. TAYLOR, A., GLADDEN,
M.H. & DURBABA, R., pp. 443-447. Plenum, London.

C. In preparation

Aggelopoulos, N.C., Logothetis N.K. and Rainer G. Responses of neurons in the nucleus
basalis to visual stimuli differing in their familiarity, category and coherence.


D. Scientific Abstracts from Conference Proceedings

Aggelopoulos, N., Bradbury, M.W., Deane, R. and Demaine, C. (1989): Brain uptake of
melatonin from the blood in the rat. Abstracts of the Society for Neuroendocrinology, University
of Bristol, Bristol, UK.


                                          Page 8 of 12
Aggelopoulos, N, Bradbury, M.W., Deane, R. and Demaine, C. (1990): The development of
regional distribution of melatonin receptors in the brain of the rat studied by quantitative
autoradiography. Abstracts of the VI Colloquium of the European Pineal Study Group, University
of Surrey, Guildford, UK.

Aggelopoulos, N., Jones, H.C. and Demaine C. (1990): Absence of melatonin receptors from the
brain of severely hydrocephalic rats revealed by quantitative in vitro autoradiography. Abstracts
of the VI Colloquium of the European Pineal Study Group, University of Surrey, Guildford, UK.

Aggelopoulos, N. and Demaine, C. (1990): Quantitative receptor autoradiography of melatonin
receptors in three non-mammalian vertebrates: The green anole lizard (Anolis carolinensis), the
edible frog (Rana esculenta) and the rainbow trout (Salmo gairdneri). Abstracts of the VI
Colloquium of the European Pineal Study Group, University of Surrey, Guildford, UK.

Aggelopoulos, N. and Demaine, C. (1990): Neurophysiology of melatonin action on the
suprachiasmatic nuclei of the brain of the adult rat, in vivo. Abstracts of the VI Colloquium of the
European Pineal Study Group, University of Surrey, Guildford, UK.

Aggelopoulos, N.C., Bawa, P. and Edgley, S.A. (1993): Interneurones of the midlumbar spinal
cord excited by group II input from synergistic hip muscles. Abstracts of the XXXII Congress of
the International Union of Physiological Sciences (IUPS), Glasgow, UK, Aug 1-6, 170.6/P.

Aggelopoulos, N.C. and Edgley, S.A. (1994): Segmental localization of the relays mediating
crossed group II inhibition of hindlimb motoneurones in the spinal cord of the anaesthetized cat.
Journal of Physiology (London) 475, 40P.

Aggelopoulos, N.C., Duke, C. and Edgley, S.A. (1994): Non-uniform conduction time in the
olivocerebellar pathway in the anaesthetized cat. Journal of Physiology (London) 476, 26P.

Aggelopoulos, N.C., Clarke, R.W. and Edgley S.A. (1994): Evidence for a descending
serotonergic control of crossed group II inhibition in the cat spinal cord. Journal of Physiology
(London) 480, 71P.

Aggelopoulos, N.C., Clarke, R.W. and Edgley S.A. (1994): Descending serotonergic control of
crossed group II inhibition in the spinal cord of the cat. Abstracts of the Society for Neuroscience,
24th Annual Meeting, Miami Beach, Florida, 651.7.

Aggelopoulos, N.C., Chakrabarty, S. and Edgley, S.A. (1995): Evoked changes in the excitability
of presynaptic terminals of cat midlumbar premotor interneurones. Journal of Physiology 487,
91P.

Aggelopoulos, N.C., Baker, M.R., Javid, M. & Edgley, S.A. (1997) Activation of climbing fibre
pathways to the rat cerebellar cortex by cerebral corticofugal pathways. Journal of Physiology
504, 113P

Aggelopoulos, N.C., Brown, S.J., Demaine, C., Harris, N.G. & Jones, H.C. (1998) Brain
distribution of melatonin receptors in the H-Tx rat with congenital hydrocephalus. European
Journal of Neuroscience 10 (Suppl. 10), Abstract 017.02, p.31 from the 1st Meeting of the
Federation of European Neuroscience Societies (FENS), Berlin



                                           Page 9 of 12
Aggelopoulos, N.C. & Meissl, H. (1998) Responses of suprachiasmatic neurones to retinal
illumination during photopic and scotopic conditions in the rat. Journal of Physiology 509, 88P

Aggelopoulos, N.C. & Meissl, H (1999) The sensitivity of retinal ganglion cells of the rat to
ultraviolet light. Journal of Physiology 518,106P

Aggelopoulos, N.C. (1999) Melatonin receptors in the brains of two tropical amphibians, Bufo
marinus and Bufo regularis. Abstracts of the EPS 99 Colloquium, European Pineal Society,
Tours.

Aggelopoulos, N.C. & Meissl, H. (1999) Neuronal responses to retinal illumination under
photopic and scotopic conditions in the suprachiasmatic nuclei of the rat. Abstracts of the EPS 99
Colloquium, European Pineal Society, Tours, France.

Aggelopoulos, N.C., Chakrabarty, S. & Edgley, S.A. (1999) Transmission from group II muscle
afferents in the midlumbar spinal segments is not depressed by stimulation of corticospinal fibres.
Journal of Physiology 521, pp.43P

Aggelopoulos, N.C. & Meissl, H (2000) Rod-cone antagonism: a novel type of visual antagonism
in the responses of retinal ganglion cells. Cambridge Meeting of the Physiological Society, 18-20
July 2000.

Aggelopoulos, N.C. & Meissl, H (2000) Extended sensitivity spectra for the retinal
photoreceptors and the capacity for ultraviolet vision. Colour Group Meeting on “Colour Vision:
Basic Studies and Clinical Applications”, City University, London, 6 November 2000

Aggelopoulos, N.C. & Edgley SA. (2000) Short-latency crossed inhibitory reflex pathways from
cutaneous afferents. King’s College Meeting of the Physiological Society, 18-20 December 2000

Rolls, ET, Zheng, F & Aggelopoulos NC (2001) Responses of inferior temporal cortex neurons to
objects in natural scenes. Society for Neuroscience Abstracts 27, 2001

Rolls, ET, Aggelopoulos, NC & Zheng, F (2002) Reduced receptive field size of inferior
temporal cortex neurons and reduced effects of attention when objects are selected in natural
scenes. Vision Sciences Society Meeting, No.275, 5-10 May, Sarasota FL, USA

Aggelopoulos, NC, Rolls, ET & Franco L (2002) Information encoding in the inferior temporal
visual cortex: contributions of the firing rates and the correlations between the firing of neurons.
Vision Sciences Society Meeting, No 425, 5-10 May, Sarasota FL, USA

Franco, L., Rolls, E.T., Aggelopoulos N. & Treves A. (2002) Information encoding in the inferior
temporal cortex: little redundancy or synergy between simultaneously recorded neurons.
Abstracts of the Society for Neuroscience, 32nd Annual Meeting, Orlando, Florida, 160.6.

Aggelopoulos NC, Rolls ET & Franco L (2003) Natural scene perception: some inferior temporal
cortex neurons convey information about the location of stimuli with respect to the fovea. Society
for Neuroscience Abstracts No. 659.1, 8-12 November, New Orleans, USA

Aggelopoulos NC & Rolls ET (2004) Rapid view-invariant learning of novel objects in the
inferior temporal cortex (IT) of macaques. A052.1 4TH forum of European Neuroscience
(FENS), Lisbon 10-14 July 2004

                                           Page 10 of 12
Aggelopoulos NC (2004) The relative position of objects in a natural scene as represented in the
inferior temporal cortex (IT). Gordon Conference on Sensory Coding and the Natural
Environment, Queens College Oxford 5-10 September 2004

Aggelopoulos NC, Franco L, Jerez JM & Rolls ET (2008) The sparseness of stimulus encoding
by single neurons and by populations of neurons in the inferior temporal cortex. Abstracts of the
AREADNE Conference, Santorini, Greece 26-29 June2008

Aggelopoulos NC, Liebe S, Logothetis NK & Rainer G (2009) Dependence of a cognitive task on
acetylcholine. Data Mining in Biomedicine, International Conference on Computational
Neuroscience at the Athens Institute of Technology (ΑΙΤ) in collaboration with the Kokkalis
Foundation, May 7-8, 2009.

Aggelopoulos NC, Liebe S, Logothetis NK & Rainer G (2009) Dependence of a visual
categorisation task on acetylcholine. European Conference on Visual Perception (ECVP)
Regensburg, Germany, 24-28th August 2009

Aggelopoulos NC, Liebe S, Logothetis NK & Rainer G The effects of scopolamine on visual
categorization in macaques (2009) 23rd Hellenic Society for Neuroscience (HSfN) Meeting
jointly with the 41st European Brain and Behaviour Society (EBBS) Meeting in Rodos Palace,
Rhodes, Greece, 13-18 September 2009

Aggelopoulos NC, Melano T, Logothetis NK and Rainer G (2010) Cholinergic dependence of a
cognitive task. Abstracts of the AREADNE Conference, Santorini, Greece 17-20 June2010.


E. Presentations in Seminars and Symposia

Aggelopoulos, N.C. and Edgley, S.A. (1994): Interneurones of the midlumbar segments of the
spinal cord. The 6th Young Physiologists Symposium, University of Bristol, Bristol, UK, 23
May.

Departmental Seminar (Thursday Duets), Department of Anatomy, University of Cambridge,
February 1996. The descending control of crossed group II inhibition in the spinal cord.

Fourth Annual Colloquium of the Deutsche Physiologische Gesellschaft (DPG), Centerprogram
“Functional and adaptive mechanisms of circadian systems“, University of Munich, 22-24 March
1999. Responses of neurons of the hypothalamic suprachiasmatic nuclei to retinal illumination
during photopic and scotopic conditions.

Departmental Seminar (Thursday duets), Department of Anatomy, University of Cambridge,
October 1999. The visual hypothalamus.

Seminar, Department of Biology, University of Patras, Patras, Greece, 31 March 2005: Receptive
fields of visual neurons in the inferior temporal cortex.

Seminar, INCM – CNRS, Marsaille France, 8 November 2005: Receptive fields of visual neurons
in the inferior temporal cortex.

Seminar, Brain and Research Center (CerCo), Toulouse, France, 2 March 2007: The receptive

                                         Page 11 of 12
fields of visual neurons of the Inferior Temporal Cortex

Seminar, Physiology Department, University of Crete, Heraklion, Greece, 5 March 2007: The
information provided by the discharge rate and the correlation of discharges in visual neurons of
the temporal cortex

Seminar, Biology Department, University of Ioannina, Greece, 9 March 2007: Representation of
objects in the brain.

Seminar Department of Psychology, University of Ioannina, Greece, 2 May 2007: The learning
and representation of objects.

Seminar, Department of Neurology, University of Ioannina Medical School, Greece, 3 May 2007:
Spinal sensorimotor reflexes and locomotion.

Seminar, Department of Biology, University of Crete, Greece, 8 May 2007: Circadian rhythms,
seasonal cycles and biological clocks.

Seminar, Department of Physiology, University of Patras, Greece, 16 May 2007: Information
provided by the firing rates and by spike-synchrony in visual neurons of the temporal lobe.

Seminar, Department of Physiology, University of Crete Medical School, Greece, 23 May 2008:
From sensation to perception.

Seminar, Max Planck Institute for Brain Research, Frankfurt, 26 May 2008 : Object perception in
natural scenes: information encoding by simultaneously recorded neurons in the inferior temporal
cortex.

Seminar, Department of Physiology, University of Ioannina, Greece, 14 May 2009: From
sensation to perception.

Workshop: Tetrode recording and spike sorting, Max Planck Institute for Biological Cybernetics,
Tuebingen, Germany, 2 Dec 2010: Commercially available spike sorting software.

Seminar, Max Planck Institute for Brain Research, Frankfurt, 9 December 2010 : The
representation of objects in the inferior temporal cortex of the macaque monkey.

Seminar, University of Bonn Medical Center, Life and Brain Center, 27th June 2011: The
representation of objects in the inferior temporal cortex of the macaque monkey.




                                         Page 12 of 12

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Aggelopoulos cv

  • 1. Nikolaos C. Aggelopoulos BSc, MSc, PhD Spemannstrasse 38 72076 Tübingen Germany Curriculum Vitae Page 1 of 12
  • 2. Curriculum Vitae Name: Nikolaos C. Aggelopoulos I. PERSONAL DATA Date of birth: August 20th, 1962 Nationality: Greek Correspondence: Neurophysiology Department, Max-Planck-Instiut fuer Biologische Kybernetik, Spemannstr. 38, 72076 Tuebingen, Germany. Awards: a) Vasileus Pavlos National Institute Scholarship, Greece, 1980. b) Award of Distinction on conference of BSc. c) Max Planck Institute Fellowship, Germany 1997 Current Position: Postdoctoral Research Associate, supported by the BMBF. Current memberships: a) Physiological Society, UK b) Hellenic Society for Neuroscience (HSN) References: (a) Prof Stephen A. Edgley, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK. Tel: +44 1223 333757 e-mail: sae1000@cus.cam.ac.uk (b) PD Dr Hilmar Meissl, Max Planck Institute for Brain Research, Deutschordenstr. 46, 60528 Frankfurt, Germany. Tel: +49 69 967 69 239 e-mail: meissl@mpih- frankfurt.mpg.de (c) Prof Edmund T Rolls, formerly Department of Experimental Psychology, University of Oxford, now retired. Oxford Centre for Computational Neuroscience, Oxford, UK. e-mail: Edmund.Rolls@oxcns.org (d) Prof Nikos K Logothetis, Max Planck Institute for Biological Cybernetics, Spemannstr. 21, 72076 Tuebingen, Germany, Tel: +49 7071 601651 e-mail: Nikos.Logothetis@tuebingen.mpg.de Page 2 of 12
  • 3. II. ACADEMIC DEGREES Year Degree University Country Subject 1985 BSc McGill University CANADA Biology 1986 MSc University of London UK Neurological Science 1990 PhD University of London UK Physiology III. UNIVERSITY EDUCATION Time Institution Country Subject 1981/82 Lakehead University, Ontario CANADA Biology 1982-85 McGill University, Montreal, CANADA Neurobiology & Quebec Comparative Physiology 1985-1986 University College, UK Neurological Science University of London 1987-1990 King's College, UK Physiology University of London PhD thesis titled: Melatonin receptors target sites in the brain. IV. PROFESSIONAL BACKGROUND Time Position Institution 7/90-7/92 National Service Army (GREECE) 8/92-5/97 Postdoctoral Research Associate Department of Anatomy University of Cambridge, UK 5/97-5/99 Postdoctoral Fellow Max Planck Institute, Bad Nauheim 5/99-11/00 Postdoctoral Research Associate Department of Anatomy, University of Cambridge, UK 11/00-01/06 Postdoctoral Research Associate Department of Experimental Psychology, University of Oxford, UK 02/06-02-/07 Research Scholar Psychology Department, Princeton University, USA 06/07-present Postdoctoral Research Associate Max Planck Institute, Tuebingen Page 3 of 12
  • 4. V. TEACHING Neurophysiology demonstrations (1987-1990) for 1st and 2nd year physiology students at King's College London, Biomedical Sciences Division. Neuroanatomy demonstrations (1995) for 2nd year veterinary students in neuroanatomy. Tutorials for part Ib medical students at the University of Cambridge: (a) Neurobiology Ib, Emmanuel College (1994) - 12 students. (b) Neurobiology Ib, Sidney Sussex College (1995) - 7 students. (c) Neurobiology Ib, St Johns College (1996) - 15 students. Supervision of a medical student on a summer research project funded by a Nuffield Foundation Undergraduate Research Bursary (1994) at the University of Cambridge. Subject: The distribution and density of specific high-affinity melatonin receptors in the brain during development. Supervision of a Masters student’s lab rotation on a BMBF-funded project on Responses of neurons in the nucleus basalis to visual stimuli differing in their familiarity, category and coherence (2011) at the Max Planck Institute for Biological Cybernetics. Co-supervision of undergraduate and graduate students working in the lab at the Universities of Cambridge (1993-1999) and Oxford (2003-2005). Invigilation duties in examinations 1987-2000. VI. FURTHER EDUCATION/ TRAINING Staff development course in Effective Teaching, University of Cambridge, 1993 Workshop in voltage and patch clamp techniques, FENS 2000, Brighton Conference Centre, 24 June 2000. Practical Workshop in temperature control and recording chambers, FENS 2000, Brighton Conference Centre, 24 June 2000. Laboratory Animal Management and Welfare Modules 1-3, University of Oxford Veterinary Services, November 2000 Autumn School of Cognitive Neuroscience, University of Oxford, supported by the MRC Interdisciplinary Research Centre for Cognitive Neuroscience, McDonnell Centre for Cognitive Neuroscience and the Guarantors of Brain, 30 September - 3 October 2002 Autumn School of Cognitive Neuroscience, University of Oxford, supported by the MRC Interdisciplinary Research Centre for Cognitive Neuroscience, McDonnell Centre for Cognitive Neuroscience and the Guarantors of Brain, 29 September-2 October 2003 Page 4 of 12
  • 5. Developments in Neural Probe Technologies and Applications VI: a satellite symposium at the Annual Meeting of the Society for Neuroscience, New Orleans, 7 November 2003 Laboratory Animal Management and Welfare Modules 4, University of Oxford Veterinary Services, September 2004 Autumn School of Cognitive Neuroscience, University of Oxford, supported by the MRC Interdisciplinary Research Centre for Cognitive Neuroscience, McDonnell Centre for Cognitive Neuroscience and the Guarantors of Brain, 28 September-1 October 2004 Laboratory Animal Management and Welfare Modules 5, University of Oxford Veterinary Services, October 2004 Autumn School of Neuroscience, University of Oxford, supported by the MRC Interdisciplinary Research Centre for Cognitive Neuroscience, McDonnell Centre for Cognitive Neuroscience and the Guarantors of Brain, 26-29 September 2005 Programming Level 3: Introduction to C and Further C; Oxford University Computing Services, 20 Oct – 30 Nov 2005 Programming Level 4: Further C; Oxford University Computing Services, 16-30 November 2005 Linux Desktop Level 2; Oxford University Computing Services, 2 – 16 November 2005 MRI certification level 1; Princeton University February-March 2006 AFNI training for fMRI analysis; Princeton University March-April 2006 Basic Matlab; University of Tuebingen October 2008 Page 5 of 12
  • 6. VII. GRANTS a) University of London Central Research Fund (1989): In vitro autoradiography of melatonin receptors. b) Nuffield Foundation Undergraduate Bursary (23/6/94 - 13/8/94): The distribution and density of specific high-affinity melatonin receptors in the brain during development. c) Royal Society Research Grant (7/7/94 - 7/9/95): Melatonin receptors. d) Max Planck Society Fellowship (1/5/97-30/4/99) The visual input to the suprachiasmatic nuclei of the rat. e) National Institutes of Health (2001-2006): £215,255 to Dr D Maxwell & Dr BA Bannatyne (IBLS - Neuroscience & Biomedical Systems), Prof E Jankowska, Dr I Hammar, Dr S Hjorth, Dr H Bengtsson (Goteborg University, Sweden), Dr S Edgley & Dr N Aggelopoulos (Cambridge University): Spinal interneurons: 5HT-NA receptors, actions, circuits. Page 6 of 12
  • 7. VIII. LIST OF PUBLICATIONS A. Full Papers Aggelopoulos N., Parnavelas, J.G. and Edmunds, S. (1989): Synaptogenesis in the dorsal lateral geniculate nucleus of the rat. Anatomy and Embryology 180, 243-257. Aggelopoulos, N.C. and Edgley, S.A. (1995): Segmental localisation of the relays mediating crossed inhibition from group II afferents in the anaesthetized cat spinal cord. Neuroscience Letters 185, 60-64. Aggelopoulos, N.C., Duke, C. and Edgley, S.A. (1995): Non-uniform conduction time in the olivocerebellar pathway in the anaesthetized cat. Journal of Physiology 486(3), 763-768. Aggelopoulos, N.C., Burton, M.J., Clarke, R.W. and Edgley S.A. (1996): Characterization of a descending system which enables crossed group II inhibitory reflex pathways in the cat spinal cord. Journal of Neuroscience 16(2), 723-729. Aggelopoulos, N.C., Bawa, P. and Edgley, S.A. (1996): Activation of midlumbar neurones by afferents from anterior hindlimb muscles in the cat. Journal of Physiology 497(3), 795-802. Aggelopoulos, N.C., Chakrabarty, S. and Edgley, S.A. (1997): Evoked excitability changes at the terminals of midlumbar premotor interneurons in the cat spinal cord. Journal of Neuroscience 17(4), 1512-1518. Aggelopoulos, N.C., Brown, S.J., Demaine C., Harris, N.G. & Jones H.C. (1998) An abnormal distribution of melatonin receptors in the newborn rat with inherited prenatal hydrocephalus. Neuroscience 80(3), 669-673. Aggelopoulos, N.C. & Meissl, H. (2000) Responses of neurones of the rat suprachiasmatic nucleus (SCN) to retinal illumination under photopic and scotopic conditions. Journal of Physiology 523(1), 211-222 Rolls, ET, Aggelopoulos NC & Zheng F. (2002) The receptive fields of inferior temporal cortex neurons in natural scenes. Journal of Neuroscience, 23: 339-348 Rolls, ET, Franco, L, Aggelopoulos, NC, and Reece, S (2003) Application of an information theoretic approach to analysing the contributions of the firing rates and correlations between the firing of neurons. Journal of Neurophysiology 89, 2810-2822. Franco, L, Rolls, ET, Aggelopoulos, NC, Treves, A (2004) The use of decoding to analyze the contribution to the information of the correlations between the firing of simultaneously recorded neurons. Experimental Brain Research, 155, 370-384. Rolls ET, Aggelopoulos NC, Franco L, Treves A (2004) Information encoding in the inferior temporal visual cortex: contributions of the firing rates and the correlations between the firing of neurons. Biological Cybernetics 90, 19-32. Page 7 of 12
  • 8. Aggelopoulos NC, Franco L, Rolls ET (2005) Object perception in natural scenes: encoding by inferior temporal cortex simultaneously recorded neurons. Journal of Neurophysiology 93, 1342- 1357. Aggelopoulos N.C. and Rolls E.T (2005) Scene perception: inferior temporal cortex neurons encode the positions of different objects in the scene. European Journal of Neuroscience 22(11), 2903-16 Edgley SA and Aggelopoulos NC (2005) Short latency crossed inhibitory reflex actions evoked from cutaneous afferents. Experimental Brain Research 171(4), 541-50 Rolls ET, Franco L, Aggelopoulos NC, Jerez JM. (2006) Information in the first spike, the order of spikes, and the number of spikes provided by neurons in the inferior temporal visual cortex. Vision Research 46(25), 4193-205 Franco L , Rolls ET , Aggelopoulos NC and Jerez JM (2007) Neuronal selectivity, population sparseness, and ergodicity in the inferior temporal visual cortex. Biological Cybernetics 96(6), 547. Aggelopoulos NC, Chakrabarty S and Edgley SA (2008) Presynaptic control of transmission through group II muscle afferents in the midlumbar and sacral segments of the spinal cord is independent of corticospinal control. Experimental Brain Research 187(1), 61-70. Aggelopoulos NC, Liebe S, Logothetis NK & Rainer G: (2011) Cholinergic control of visual categorization in macaques. Frontiers in Behavioral Neuroscience 5(73):1-10 B. Book chapters Aggelopoulos, N. and Demaine, C. (1991) The development of regional distribution of melatonin receptors in the brain of the rat studied by quantitative autoradiography. In Advances in Pineal Research, Vol. 5. Vith Colloquium of the European Pineal Study Group, Guildford, England, UK., Sep. 2-7 1990. Ed. ARENDT, J. & PEVET, P., pp.201-204. John Libbey & Co. Ltd, London, England, UK; Montrouge, France. ISBN 0-86196-270-2 Aggelopoulos, N.C., Clarke, R.W. and Edgley S.A. (1995): Descending control of a crossed spinal reflex by serotonin. In Alpha and Gamma Motor Systems, ed. TAYLOR, A., GLADDEN, M.H. & DURBABA, R., pp. 443-447. Plenum, London. C. In preparation Aggelopoulos, N.C., Logothetis N.K. and Rainer G. Responses of neurons in the nucleus basalis to visual stimuli differing in their familiarity, category and coherence. D. Scientific Abstracts from Conference Proceedings Aggelopoulos, N., Bradbury, M.W., Deane, R. and Demaine, C. (1989): Brain uptake of melatonin from the blood in the rat. Abstracts of the Society for Neuroendocrinology, University of Bristol, Bristol, UK. Page 8 of 12
  • 9. Aggelopoulos, N, Bradbury, M.W., Deane, R. and Demaine, C. (1990): The development of regional distribution of melatonin receptors in the brain of the rat studied by quantitative autoradiography. Abstracts of the VI Colloquium of the European Pineal Study Group, University of Surrey, Guildford, UK. Aggelopoulos, N., Jones, H.C. and Demaine C. (1990): Absence of melatonin receptors from the brain of severely hydrocephalic rats revealed by quantitative in vitro autoradiography. Abstracts of the VI Colloquium of the European Pineal Study Group, University of Surrey, Guildford, UK. Aggelopoulos, N. and Demaine, C. (1990): Quantitative receptor autoradiography of melatonin receptors in three non-mammalian vertebrates: The green anole lizard (Anolis carolinensis), the edible frog (Rana esculenta) and the rainbow trout (Salmo gairdneri). Abstracts of the VI Colloquium of the European Pineal Study Group, University of Surrey, Guildford, UK. Aggelopoulos, N. and Demaine, C. (1990): Neurophysiology of melatonin action on the suprachiasmatic nuclei of the brain of the adult rat, in vivo. Abstracts of the VI Colloquium of the European Pineal Study Group, University of Surrey, Guildford, UK. Aggelopoulos, N.C., Bawa, P. and Edgley, S.A. (1993): Interneurones of the midlumbar spinal cord excited by group II input from synergistic hip muscles. Abstracts of the XXXII Congress of the International Union of Physiological Sciences (IUPS), Glasgow, UK, Aug 1-6, 170.6/P. Aggelopoulos, N.C. and Edgley, S.A. (1994): Segmental localization of the relays mediating crossed group II inhibition of hindlimb motoneurones in the spinal cord of the anaesthetized cat. Journal of Physiology (London) 475, 40P. Aggelopoulos, N.C., Duke, C. and Edgley, S.A. (1994): Non-uniform conduction time in the olivocerebellar pathway in the anaesthetized cat. Journal of Physiology (London) 476, 26P. Aggelopoulos, N.C., Clarke, R.W. and Edgley S.A. (1994): Evidence for a descending serotonergic control of crossed group II inhibition in the cat spinal cord. Journal of Physiology (London) 480, 71P. Aggelopoulos, N.C., Clarke, R.W. and Edgley S.A. (1994): Descending serotonergic control of crossed group II inhibition in the spinal cord of the cat. Abstracts of the Society for Neuroscience, 24th Annual Meeting, Miami Beach, Florida, 651.7. Aggelopoulos, N.C., Chakrabarty, S. and Edgley, S.A. (1995): Evoked changes in the excitability of presynaptic terminals of cat midlumbar premotor interneurones. Journal of Physiology 487, 91P. Aggelopoulos, N.C., Baker, M.R., Javid, M. & Edgley, S.A. (1997) Activation of climbing fibre pathways to the rat cerebellar cortex by cerebral corticofugal pathways. Journal of Physiology 504, 113P Aggelopoulos, N.C., Brown, S.J., Demaine, C., Harris, N.G. & Jones, H.C. (1998) Brain distribution of melatonin receptors in the H-Tx rat with congenital hydrocephalus. European Journal of Neuroscience 10 (Suppl. 10), Abstract 017.02, p.31 from the 1st Meeting of the Federation of European Neuroscience Societies (FENS), Berlin Page 9 of 12
  • 10. Aggelopoulos, N.C. & Meissl, H. (1998) Responses of suprachiasmatic neurones to retinal illumination during photopic and scotopic conditions in the rat. Journal of Physiology 509, 88P Aggelopoulos, N.C. & Meissl, H (1999) The sensitivity of retinal ganglion cells of the rat to ultraviolet light. Journal of Physiology 518,106P Aggelopoulos, N.C. (1999) Melatonin receptors in the brains of two tropical amphibians, Bufo marinus and Bufo regularis. Abstracts of the EPS 99 Colloquium, European Pineal Society, Tours. Aggelopoulos, N.C. & Meissl, H. (1999) Neuronal responses to retinal illumination under photopic and scotopic conditions in the suprachiasmatic nuclei of the rat. Abstracts of the EPS 99 Colloquium, European Pineal Society, Tours, France. Aggelopoulos, N.C., Chakrabarty, S. & Edgley, S.A. (1999) Transmission from group II muscle afferents in the midlumbar spinal segments is not depressed by stimulation of corticospinal fibres. Journal of Physiology 521, pp.43P Aggelopoulos, N.C. & Meissl, H (2000) Rod-cone antagonism: a novel type of visual antagonism in the responses of retinal ganglion cells. Cambridge Meeting of the Physiological Society, 18-20 July 2000. Aggelopoulos, N.C. & Meissl, H (2000) Extended sensitivity spectra for the retinal photoreceptors and the capacity for ultraviolet vision. Colour Group Meeting on “Colour Vision: Basic Studies and Clinical Applications”, City University, London, 6 November 2000 Aggelopoulos, N.C. & Edgley SA. (2000) Short-latency crossed inhibitory reflex pathways from cutaneous afferents. King’s College Meeting of the Physiological Society, 18-20 December 2000 Rolls, ET, Zheng, F & Aggelopoulos NC (2001) Responses of inferior temporal cortex neurons to objects in natural scenes. Society for Neuroscience Abstracts 27, 2001 Rolls, ET, Aggelopoulos, NC & Zheng, F (2002) Reduced receptive field size of inferior temporal cortex neurons and reduced effects of attention when objects are selected in natural scenes. Vision Sciences Society Meeting, No.275, 5-10 May, Sarasota FL, USA Aggelopoulos, NC, Rolls, ET & Franco L (2002) Information encoding in the inferior temporal visual cortex: contributions of the firing rates and the correlations between the firing of neurons. Vision Sciences Society Meeting, No 425, 5-10 May, Sarasota FL, USA Franco, L., Rolls, E.T., Aggelopoulos N. & Treves A. (2002) Information encoding in the inferior temporal cortex: little redundancy or synergy between simultaneously recorded neurons. Abstracts of the Society for Neuroscience, 32nd Annual Meeting, Orlando, Florida, 160.6. Aggelopoulos NC, Rolls ET & Franco L (2003) Natural scene perception: some inferior temporal cortex neurons convey information about the location of stimuli with respect to the fovea. Society for Neuroscience Abstracts No. 659.1, 8-12 November, New Orleans, USA Aggelopoulos NC & Rolls ET (2004) Rapid view-invariant learning of novel objects in the inferior temporal cortex (IT) of macaques. A052.1 4TH forum of European Neuroscience (FENS), Lisbon 10-14 July 2004 Page 10 of 12
  • 11. Aggelopoulos NC (2004) The relative position of objects in a natural scene as represented in the inferior temporal cortex (IT). Gordon Conference on Sensory Coding and the Natural Environment, Queens College Oxford 5-10 September 2004 Aggelopoulos NC, Franco L, Jerez JM & Rolls ET (2008) The sparseness of stimulus encoding by single neurons and by populations of neurons in the inferior temporal cortex. Abstracts of the AREADNE Conference, Santorini, Greece 26-29 June2008 Aggelopoulos NC, Liebe S, Logothetis NK & Rainer G (2009) Dependence of a cognitive task on acetylcholine. Data Mining in Biomedicine, International Conference on Computational Neuroscience at the Athens Institute of Technology (ΑΙΤ) in collaboration with the Kokkalis Foundation, May 7-8, 2009. Aggelopoulos NC, Liebe S, Logothetis NK & Rainer G (2009) Dependence of a visual categorisation task on acetylcholine. European Conference on Visual Perception (ECVP) Regensburg, Germany, 24-28th August 2009 Aggelopoulos NC, Liebe S, Logothetis NK & Rainer G The effects of scopolamine on visual categorization in macaques (2009) 23rd Hellenic Society for Neuroscience (HSfN) Meeting jointly with the 41st European Brain and Behaviour Society (EBBS) Meeting in Rodos Palace, Rhodes, Greece, 13-18 September 2009 Aggelopoulos NC, Melano T, Logothetis NK and Rainer G (2010) Cholinergic dependence of a cognitive task. Abstracts of the AREADNE Conference, Santorini, Greece 17-20 June2010. E. Presentations in Seminars and Symposia Aggelopoulos, N.C. and Edgley, S.A. (1994): Interneurones of the midlumbar segments of the spinal cord. The 6th Young Physiologists Symposium, University of Bristol, Bristol, UK, 23 May. Departmental Seminar (Thursday Duets), Department of Anatomy, University of Cambridge, February 1996. The descending control of crossed group II inhibition in the spinal cord. Fourth Annual Colloquium of the Deutsche Physiologische Gesellschaft (DPG), Centerprogram “Functional and adaptive mechanisms of circadian systems“, University of Munich, 22-24 March 1999. Responses of neurons of the hypothalamic suprachiasmatic nuclei to retinal illumination during photopic and scotopic conditions. Departmental Seminar (Thursday duets), Department of Anatomy, University of Cambridge, October 1999. The visual hypothalamus. Seminar, Department of Biology, University of Patras, Patras, Greece, 31 March 2005: Receptive fields of visual neurons in the inferior temporal cortex. Seminar, INCM – CNRS, Marsaille France, 8 November 2005: Receptive fields of visual neurons in the inferior temporal cortex. Seminar, Brain and Research Center (CerCo), Toulouse, France, 2 March 2007: The receptive Page 11 of 12
  • 12. fields of visual neurons of the Inferior Temporal Cortex Seminar, Physiology Department, University of Crete, Heraklion, Greece, 5 March 2007: The information provided by the discharge rate and the correlation of discharges in visual neurons of the temporal cortex Seminar, Biology Department, University of Ioannina, Greece, 9 March 2007: Representation of objects in the brain. Seminar Department of Psychology, University of Ioannina, Greece, 2 May 2007: The learning and representation of objects. Seminar, Department of Neurology, University of Ioannina Medical School, Greece, 3 May 2007: Spinal sensorimotor reflexes and locomotion. Seminar, Department of Biology, University of Crete, Greece, 8 May 2007: Circadian rhythms, seasonal cycles and biological clocks. Seminar, Department of Physiology, University of Patras, Greece, 16 May 2007: Information provided by the firing rates and by spike-synchrony in visual neurons of the temporal lobe. Seminar, Department of Physiology, University of Crete Medical School, Greece, 23 May 2008: From sensation to perception. Seminar, Max Planck Institute for Brain Research, Frankfurt, 26 May 2008 : Object perception in natural scenes: information encoding by simultaneously recorded neurons in the inferior temporal cortex. Seminar, Department of Physiology, University of Ioannina, Greece, 14 May 2009: From sensation to perception. Workshop: Tetrode recording and spike sorting, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 2 Dec 2010: Commercially available spike sorting software. Seminar, Max Planck Institute for Brain Research, Frankfurt, 9 December 2010 : The representation of objects in the inferior temporal cortex of the macaque monkey. Seminar, University of Bonn Medical Center, Life and Brain Center, 27th June 2011: The representation of objects in the inferior temporal cortex of the macaque monkey. Page 12 of 12