The document discusses Agenda 21, a comprehensive plan of action adopted in 1992 at the United Nations Conference on Environment and Development in Rio de Janeiro to achieve sustainable development globally and locally. Agenda 21 addressed key issues like poverty reduction, industry and development, management of toxic chemicals, protection of the ozone layer, combating deforestation, conservation of biodiversity, and freshwater management. It called for integrating environmental and developmental policies, strengthening international cooperation, and increasing participation from major groups in implementing sustainable development programs.
Official Outcome Statement of the 2014 Global Landscapes Forum, held at the sidelines of the UNFCCC COP20 in Lima, from 6-7 December.
More than 1,700 world leaders, policy makers, researchers and representatives from civil society, the private sector and media met in Lima to discuss the future of land use sectors in a new climate agreement. Nine key messages form the basis of their recommendations.
Author : Global Landscapes Forum Committee
Language: English
Year: 2014
Official Outcome Statement of the 2014 Global Landscapes Forum, held at the sidelines of the UNFCCC COP20 in Lima, from 6-7 December.
More than 1,700 world leaders, policy makers, researchers and representatives from civil society, the private sector and media met in Lima to discuss the future of land use sectors in a new climate agreement. Nine key messages form the basis of their recommendations.
Author : Global Landscapes Forum Committee
Language: English
Year: 2014
Bioversity International researcher Silvia Wood explains the process of developing the post-2015 Sustainable Development Goals and areas of interest and intervention that the researchers from CGIAR and the Ecosystem Services Partnership could take. Presented at the 7th Annual Ecosystem Services Partnership Conference in Costa Rica, September 8-12, 2014.
Find out more about the Bridging Agriculture and Conservation Initiative: http://www.bioversityinternational.org/about-us/news/bridging-agriculture-conservation/
Society, government and environment chapter 3Nayan Vaghela
Society, government and environment, sustainable development, Bearing capacity of the resources, Migration, environmental ethics, different laws and legislation related to environments,, Air Act, Water Act, Wild life protection Act, illicit cutting of trees, illicit killing of wild animals, green belt, water treatment, industrial waste treatment
Civil Society Organisation’s Contribution in advancing Uganda’s Green Growth ...Dr. Joshua Zake
A presentation made during the 2nd Uganda Water and Environment Week held in Entebbe, Uganda. It highlights the contribution of the Environment and Natural Resources Civil Society Organizations to advance Uganda along the green growth path to development and transformation. Furthermore, the key considerations to address for the civil society in Uganda to effectively deliver on this role at different scales.
Bioversity International researcher Silvia Wood explains the process of developing the post-2015 Sustainable Development Goals and areas of interest and intervention that the researchers from CGIAR and the Ecosystem Services Partnership could take. Presented at the 7th Annual Ecosystem Services Partnership Conference in Costa Rica, September 8-12, 2014.
Find out more about the Bridging Agriculture and Conservation Initiative: http://www.bioversityinternational.org/about-us/news/bridging-agriculture-conservation/
Society, government and environment chapter 3Nayan Vaghela
Society, government and environment, sustainable development, Bearing capacity of the resources, Migration, environmental ethics, different laws and legislation related to environments,, Air Act, Water Act, Wild life protection Act, illicit cutting of trees, illicit killing of wild animals, green belt, water treatment, industrial waste treatment
Civil Society Organisation’s Contribution in advancing Uganda’s Green Growth ...Dr. Joshua Zake
A presentation made during the 2nd Uganda Water and Environment Week held in Entebbe, Uganda. It highlights the contribution of the Environment and Natural Resources Civil Society Organizations to advance Uganda along the green growth path to development and transformation. Furthermore, the key considerations to address for the civil society in Uganda to effectively deliver on this role at different scales.
This pdf is about the Schizophrenia.
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Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
2. 1992 The Rio Earth Summit…
Agenda 21 - Action Plan/ “Blueprint for Sustainable Development”
(40 chapters, 300 pages)
Sustainable Development = Development that meets the needs of
the present without compromising the ability of future generations
to meet their needs.
Background/
History…
1987 The Brundtland Commission…
3. Agenda 21
• Agenda 21 is a comprehensive plan of action to be taken globally,
nationally and locally by organizations of the United Nations
System, Governments, and Major Groups in every area in which
human impacts on the environment.
• Agenda 21, the Rio Declaration on Environment and Development,
and the Statement of principles for the Sustainable Management
of Forests were adopted by more than 178 Governments at the
United Nations Conference on Environment and Development
(UNCED) held in Rio de Janeiro, Brazil, 3 to 14 June 1992.
• The full implementation of Agenda 21, the Programme for Further
Implementation of Agenda 21 and the Commitments to the Rio
principles, were strongly reaffirmed at the World Summit on
Sustainable Development (WSSD) held in Johannesburg, South
Africa from 26 August to 4 September 2002.
4. 2000 UN Millenium Summit
Halve
Extreme Poverty
Universal
Primary
Education
Empowerment of
Women/ gender
equality
Reduce <5
mortality
by 2/3
Reduce maternal
mortality
by 3/4
Reverse spread
of diseases, esp.
HIV/AIDS, Malaria
Ensure
Environmental
Sustainability
Form a
Global Development
Partnership
for aid, trade, debt relief
Millenium
Development
Goals
by 2015
Background/
History cont’d…
5. 2.8 billion living
on < $2/day)
Growing gap
between rich & poor
6 million children
died from hunger
In 10 years
1.1 billion lack
clean water
27% coral reefs
Seriously threatened
(up from 10%)
Background/
History cont’d…
10 years after Rio
Declining indicators
Greenhouse gas
emissions up 9%
Extinctions
on the rise
2002 The World Summit
on Sustainable Development…
8. 1. COMBATING POVERTY
• Poverty is a complex multidimensional problem with origins in both the
national and international domains.
• While managing resources sustainably, an environmental policy that
focuses mainly on the conservation and protection of resources must
take due account of those who depend on the resources for their
livelihoods. Otherwise it could have an adverse impact both on poverty
and on chances for long-term success in resource and environmental
conservation.
• A specific anti-poverty strategy is therefore one of the basic conditions
for ensuring sustainable development. An effective strategy for tackling
the problems of poverty, development and environment simultaneously
should begin by focusing on resources, production and people and
should cover demographic issues, enhanced health care and education,
the rights of women, the role of youth and of indigenous people and
local communities and a democratic participation process in association
with improved governance.
9. 2. Industrial Development
• Industry is essential for the production of goods and
services and is a major source of employment and income,
and industrial development as such is essential for
economic growth.
• At the same time, industry is a major resource and
materials user and consequently industrial activities result
in emissions into the atmosphere and the environment as a
whole.
• Protection of the atmosphere can be enhanced, inter alia,
by increasing resource and materials efficiency in industry,
installing or improving pollution abatement technologies
and replacing chlorofluorocarbons (CFCs) and other ozone-
depleting substances with appropriate substitutes, as well
as by reducing wastes and byproducts.
10. 3. Management of toxic Chemicals
• A substantial use of chemicals is essential to meet the social and economic goals
of the world community and today's best practice demonstrates that they can
be used widely in a cost-effective manner and with a high degree of safety.
• However, a great deal remains to be done to ensure the environmentally sound
management of toxic chemicals, within the principles of sustainable
development and improved quality of life for humankind.
• Two of the major problems, particularly in developing countries, are (a) lack of
sufficient scientific information for the assessment of risks entailed by the use of
a great number of chemicals, and (b) lack of resources for assessment of
chemicals for which data are at hand.
• A considerable number of international bodies are involved in work on chemical
safety. In many countries work programmes for the promotion of chemical
safety are in place. Such work has international implications, as chemical risks
do not respect national boundaries. However, a significant strengthening of both
national and international efforts is needed to achieve an environmentally
sound management of chemicals.
11. 4. Preventing stratospheric ozone
depletion
• Analysis of recent scientific data has confirmed the growing
concern about the continuing depletion of the Earth's
stratospheric ozone layer by reactive chlorine and bromine
from man-made CFCs, halogens and related substances.
• While the 1985 Vienna Convention for the Protection of the
Ozone Layer and the 1987 Montreal Protocol on Substances
that Deplete the Ozone Layer (as amended in London in
1990) were important steps in international action, the
total chlorine loading of the atmosphere of ozone-depleting
substances has continued to rise. This can be changed
through compliance with the control measures identified
within the Protocol.
12. 5. Combating Deforestation
• There are major weaknesses in the policies, methods and mechanisms adopted to
support and develop the multiple ecological, economic, social and cultural roles of
trees, forests and forest lands. Many developed countries are confronted with the
effects of air pollution and fire damage on their forests.
• More effective measures and approaches are often required at the national level to
improve and harmonize policy formulation, planning and programming; legislative
measures and instruments; development patterns; participation of the general
public, especially women and indigenous people; involvement of youth; roles of the
private sector, local organizations, non-governmental organizations and
cooperatives; development of technical and multidisciplinary skills and quality of
human resources; forestry extension and public education; research capability and
support; administrative structures and mechanisms, including intersectoral
coordination, decentralization and responsibility and incentive systems; and
dissemination of information and public relations.
• This is especially important to ensure a rational and holistic approach to the
sustainable and environmentally sound development of forests. The need for
securing the multiple roles of forests and forest lands through adequate and
appropriate institutional strengthening has been repeatedly emphasized in many of
the reports, decisions and recommendations of FAO, ITTO, UNEP, the World Bank,
IUCN and other organizations.
13. 6. Conservation of Biological diversity
• Despite mounting efforts over the past 20 years, the loss of the world's
biological diversity, mainly from habitat destruction, over-harvesting,
pollution and the inappropriate introduction of foreign plants and animals,
has continued.
• Biological resources constitute a capital asset with great potential for
yielding sustainable benefits. Urgent and decisive action is needed to
conserve and maintain genes, species and ecosystems, with a view to the
sustainable management and use of biological resources.
• Effective national action and international cooperation is required for the in
situ protection of ecosystems, for the ex situ conservation of biological and
genetic resources and for the enhancement of ecosystem functions.
• The participation and support of local communities are elements essential
to the success of such an approach. Recent advances in biotechnology have
pointed up the likely potential for agriculture, health and welfare and for
the environmental purposes of the genetic material contained in plants,
animals and micro-organisms.
14. 7. Freshwater management
• The extent to which water resources development contributes to economic
productivity and social well-being is not usually appreciated, although all social and
economic activities rely heavily on the supply and quality of freshwater.
• As populations and economic activities grow, many countries are rapidly reaching
conditions of water scarcity or facing limits to economic development. Water
demands are increasing rapidly, with 70-80 per cent required for irrigation, less
than 20 per cent for industry and a mere 6 per cent for domestic consumption.
• The holistic management of freshwater as a finite and vulnerable resource, and
the integration of sectoral water plans and programmes within the framework of
national economic and social policy, are of paramount importance for action in the
1990s and beyond.
• The fragmentation of responsibilities for water resources development among
sectoral agencies is proving, however, to be an even greater impediment to
promoting integrated water management than had been anticipated. Effective
implementation and coordination mechanisms are required.