Ageing and Physiology, its various theories, Mechanism of ageing, types of aging

1. DR MEGALA
2ND
YEAR MD
DEPARTMENT OF YOGA
AGEING &
PHYSIOLOGY

2. INTRODUCTION
• Starts from the moment we enter
life,natural process & not a disease
• Occurs at different rates
• It is a slow,irreversible,chronic process, the
origins of which are not necessarily well
understood but universally accepted.
• Occur in all of the body's cells, tissues, and
organs, and these changes affect the
functioning of all body systems.
• Involves a decline in biological functions
and is accompanied by psychological,
behavioural, and other changes

32. CARDIOVASCULAR SYSTEM
AGE ASSOCIATED
CHANGES
COMMON CLINICAL
CONSEQUENCES
Valves calcium deposit Cardiac conduction
problem
Pacemaker cell loss(SA
node)
Fibrous tissue/fat deposit
Dysrhythmias
Decreased response to
cardiac glycosides
Decreased heart rate and
increased cardiac
contractility
Arteries thickens/stiffens
Ventricular
cardiomyocytes
hypertrophy
Moderate increase in SBP
Atherosclerotic plaques
or HTN

33. RESPIRATORY SYSTEM
AGE ASSOCIATED CHANGES COMMON CLINICAL
CONSEQUENCES
Vital capacity
FEV
Chest wall compliance
Increased alveolar-arterial
gradient
Reduced alveolar elasticity
and number of functional
alveoli
Decreased surface area for
gaseous exchange
Reduced reserve capacity
Cilia and glandular cell
activity reduced
Lung macrophages-less
effective
Cough- less forcefull
Increased risk of respiratory
infections

41. Reference
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