- Adrenal disorders include primary hypoadrenalism (Addison's disease), congenital adrenal hyperplasia, primary hyperaldosteronism, and pheochromocytoma. - Addison's disease is caused by destruction of the adrenal cortex leading to deficiencies in glucocorticoids, mineralocorticoids, and sex steroids. Common causes include autoimmune disease and tuberculosis. - Congenital adrenal hyperplasia is caused by enzyme deficiencies leading to cortisol deficiency and excess androgen production, often causing virilization in females. - Primary hyperaldosteronism is characterized by excessive aldosterone secretion causing hypokalemia and hypertension.