This document provides guidance on developing a strategic framework to achieve success with limited resources. It discusses understanding an organization's core strategies, outcomes, and impact. It also covers clarifying indicators of success and creating an opportunity screen. The strategic framework links strategies, enabling outcomes, and impact, with strategies informing outcomes to achieve the desired impact. Indicators of success should focus on outcomes, not activities, and measure how the organization will know it has created desired outcomes. The opportunity screen helps evaluate new opportunities based on alignment with the organization's mission, outcomes, strategies, strengths, and resource capabilities.