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Curcumin-95
   An amazing South
 Indian spice with wide                                                 100 Vegi-Caps
                                                                        Serving Size:              1 Capsule


    reaching health                                                     Turmeric (Curcuma longa Linn.)
                                                                        Extract (95% Curcuminoids) 500 mg
                                                                        Typical Distribution/Distribution type:
                                                                          Curcumin (diferuloylmethane)365 mg


        benefits
                                                                          Demethoxycurcumin              80 mg
                                                                          Bis-Demethoxycurcumin          10 mg
                                                                          Other curcuminoids             20 mg
                                                                        Key Features:           Standardized
• Anti-inflammatory                     • Anti-tumor                    Curcumin extract.
                                                                        Suggested Use:

• Lowers cholesterol                  • Fights bacteria                 Take one to eight capsules per day, or
                                                                        as directed by a qualified health care
                                                                        practitioner.
                                                                        Main Indication:
Antioxidant and cancer protection                                       As reported by literature:
                                                                        • Anti-oxidant.
Curcumin is an extract of the herb turmeric (Curcuma longa Linn)        • Anti-inflammatory.
which has wide-ranging health benefits. It is well known to have        • Gastro-intestinal effects.
antioxidant effects, preventing cellular damage, and it reduces the     • Cardiovascular effects.
                                                                        • Lipid metabolism.
production of inflammatory signals. It is also able to block the        • Anti-bacterial/Anti-fungal.
growth of abnormal cells, stopping cancer before it begins.             • Anti-viral.
                                                                        • Anti-tumor activity
A multi-tasking supplement                                              Cautions:
                                                                        None Known.
Curcumin protects the liver from several toxins and regulates lipid
                                                                        Pregnancy / Nursing
metabolism to decrease cholesterol levels. It protects the gastric      No studies have been conducted. Best
mucosa against irritants. It can fight off many unwanted invaders       to avoid.
such as the bacteria Staphylococcus aureus and various fungal           Source:
infections, and has even been shown to be a useful ally against HIV.    Root.
                                                                        Complementary Products:
Curcumin is able to protect the body from damage in a number of         Lyprinol, Maxi Boz, Opti-Guggul

ways. AOR's formula takes full advantage of this ancient herb with
powerful modern health benefits.



          Advanced
    Orthomolecular Research     www.aor.ca
 To purchase9AOR products online, ,click here to visit T2E 6X8 Canada
        AOR   - 4101 19th Street NE Calgary, Alberta CURESELF.COM
                                                                       Innovative Research
                                                                       & Scientific Integrity
Curcumin-95
Curcuma Longa is a perennial herb that belongs to the ginger family. The rhizome is extensively used for
imparting color and flavor to food including curries. As a powder, called turmeric, it is also used for medicinal
and religious ceremonies.
Chemistry
Curcuma longa rhizomes yield about 8% essential oils and 10% fatty oil. The volatile oils are probably
responsible for curcumin's antispasmodic activity. Borneol is present in the essential oil fraction and is largely
responsible for the digestion-improving properties.
Antioxidant
Numerous studies have shown that the various constituents of curcuma longa possess potent antioxidant
properties, and curcumin has been reported to be an effective agent against lipid peroxidation.
Anti-inflammatory
Curcumin has been found to be effective in several animal models of inflammation, and is considered a
potential non-steroidal anti-inflammatory agent. The mechanism of curcumin's anti-inflammatory action is
not yet known, although several cellular mechanisms have been suggested, including affecting steroid release
from the adrenal cortex, blocking pro-inflammatory enzymes, and inhibiting the production of pro-
inflammatory mediators. The overexpression of pro-inflammatory mediators contributes to diseases such as
Alzheimer's, cerebral ischemia and multiple sclerosis. The ability of curcumin to decrease inflammation
presents an approach to slow the progression of these diseases.
Gastro-intestinal effects
Curcumin increases mucin content, thereby protecting the gastric mucosa against irritants. Curcumin also
possesses anti-spasmodic properties. Curcumin showed liver protective effects against carbon tetrachloride,
D-Galactosamine and peroxide induced cytotoxicity, and increased bile acid production in animals.
Cardiovascular effects
A sharp and transient hypotensive effect of curcumin was reported in dogs. Curcumin also inhibited collagen
and adrenaline-induced aggregation of platelets, thereby helping to prevent clot formation.
Lipid metabolism
Animals fed with curcumin and cholesterol had only half to one-third of the serum and liver cholesterol levels
compared to the controlled groups receiving cholesterol alone.
Anti-bacterial/Anti-fungal
Curcumin has been shown to inhibit the growth of most organisms including Staphylococcus aureus (which
is responsible for a number of diseases including skin infections, pneumonia, and food poisoning),
Streptococci (best known for strep throat and flesh eating disease), corynebacterium (responsible for
diphtheria), and micrococcus pyogenes. The crude ether and chloroform extracts of curcuma longa showed
anti-fungal activity against several parasitic fungi as well as anti-amoebic activity against Entamoeba
histolytica.
Anti-viral
Curcumin has been shown to be an effective ally in the treatment against HIV. Curcumin was effective in
inhibiting the replication of HIV in both acutely infected and chronically infected cells.
Anti-tumor activity
The anti-tumor activity of various extracts of curcuma longa has been remarked by several researchers.
Animal studies have found that curcumin can significantly impede the production of tumours, and inhibits the
progression of colon and skin cancers. Curcumin is able to alter gene regulation, and it blocks the formation
of new blood vessels that feed tumours. In a clinical trial, supplemental curcumin was found to improve the
histology of precancerous lesions in patients with various forms of cancer.

            Advanced
      Orthomolecular Research          www.aor.ca
             To purchase AOR productsNE , Calgary, AlbertatoT2E 6X8 Canada
               AOR 9 - 4101 19th Street online, click here visit CURESELF.COM
                                                                                     Innovative Research
                                                                                     & Scientific Integrity

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A O R Curcumin95

  • 1. Curcumin-95 An amazing South Indian spice with wide 100 Vegi-Caps Serving Size: 1 Capsule reaching health Turmeric (Curcuma longa Linn.) Extract (95% Curcuminoids) 500 mg Typical Distribution/Distribution type: Curcumin (diferuloylmethane)365 mg benefits Demethoxycurcumin 80 mg Bis-Demethoxycurcumin 10 mg Other curcuminoids 20 mg Key Features: Standardized • Anti-inflammatory • Anti-tumor Curcumin extract. Suggested Use: • Lowers cholesterol • Fights bacteria Take one to eight capsules per day, or as directed by a qualified health care practitioner. Main Indication: Antioxidant and cancer protection As reported by literature: • Anti-oxidant. Curcumin is an extract of the herb turmeric (Curcuma longa Linn) • Anti-inflammatory. which has wide-ranging health benefits. It is well known to have • Gastro-intestinal effects. antioxidant effects, preventing cellular damage, and it reduces the • Cardiovascular effects. • Lipid metabolism. production of inflammatory signals. It is also able to block the • Anti-bacterial/Anti-fungal. growth of abnormal cells, stopping cancer before it begins. • Anti-viral. • Anti-tumor activity A multi-tasking supplement Cautions: None Known. Curcumin protects the liver from several toxins and regulates lipid Pregnancy / Nursing metabolism to decrease cholesterol levels. It protects the gastric No studies have been conducted. Best mucosa against irritants. It can fight off many unwanted invaders to avoid. such as the bacteria Staphylococcus aureus and various fungal Source: infections, and has even been shown to be a useful ally against HIV. Root. Complementary Products: Curcumin is able to protect the body from damage in a number of Lyprinol, Maxi Boz, Opti-Guggul ways. AOR's formula takes full advantage of this ancient herb with powerful modern health benefits. Advanced Orthomolecular Research www.aor.ca To purchase9AOR products online, ,click here to visit T2E 6X8 Canada AOR - 4101 19th Street NE Calgary, Alberta CURESELF.COM Innovative Research & Scientific Integrity
  • 2. Curcumin-95 Curcuma Longa is a perennial herb that belongs to the ginger family. The rhizome is extensively used for imparting color and flavor to food including curries. As a powder, called turmeric, it is also used for medicinal and religious ceremonies. Chemistry Curcuma longa rhizomes yield about 8% essential oils and 10% fatty oil. The volatile oils are probably responsible for curcumin's antispasmodic activity. Borneol is present in the essential oil fraction and is largely responsible for the digestion-improving properties. Antioxidant Numerous studies have shown that the various constituents of curcuma longa possess potent antioxidant properties, and curcumin has been reported to be an effective agent against lipid peroxidation. Anti-inflammatory Curcumin has been found to be effective in several animal models of inflammation, and is considered a potential non-steroidal anti-inflammatory agent. The mechanism of curcumin's anti-inflammatory action is not yet known, although several cellular mechanisms have been suggested, including affecting steroid release from the adrenal cortex, blocking pro-inflammatory enzymes, and inhibiting the production of pro- inflammatory mediators. The overexpression of pro-inflammatory mediators contributes to diseases such as Alzheimer's, cerebral ischemia and multiple sclerosis. The ability of curcumin to decrease inflammation presents an approach to slow the progression of these diseases. Gastro-intestinal effects Curcumin increases mucin content, thereby protecting the gastric mucosa against irritants. Curcumin also possesses anti-spasmodic properties. Curcumin showed liver protective effects against carbon tetrachloride, D-Galactosamine and peroxide induced cytotoxicity, and increased bile acid production in animals. Cardiovascular effects A sharp and transient hypotensive effect of curcumin was reported in dogs. Curcumin also inhibited collagen and adrenaline-induced aggregation of platelets, thereby helping to prevent clot formation. Lipid metabolism Animals fed with curcumin and cholesterol had only half to one-third of the serum and liver cholesterol levels compared to the controlled groups receiving cholesterol alone. Anti-bacterial/Anti-fungal Curcumin has been shown to inhibit the growth of most organisms including Staphylococcus aureus (which is responsible for a number of diseases including skin infections, pneumonia, and food poisoning), Streptococci (best known for strep throat and flesh eating disease), corynebacterium (responsible for diphtheria), and micrococcus pyogenes. The crude ether and chloroform extracts of curcuma longa showed anti-fungal activity against several parasitic fungi as well as anti-amoebic activity against Entamoeba histolytica. Anti-viral Curcumin has been shown to be an effective ally in the treatment against HIV. Curcumin was effective in inhibiting the replication of HIV in both acutely infected and chronically infected cells. Anti-tumor activity The anti-tumor activity of various extracts of curcuma longa has been remarked by several researchers. Animal studies have found that curcumin can significantly impede the production of tumours, and inhibits the progression of colon and skin cancers. Curcumin is able to alter gene regulation, and it blocks the formation of new blood vessels that feed tumours. In a clinical trial, supplemental curcumin was found to improve the histology of precancerous lesions in patients with various forms of cancer. Advanced Orthomolecular Research www.aor.ca To purchase AOR productsNE , Calgary, AlbertatoT2E 6X8 Canada AOR 9 - 4101 19th Street online, click here visit CURESELF.COM Innovative Research & Scientific Integrity