BBB is one of the fastest-growing Bio-Incubator in Delhi NCR for all young Bio-entrepreneurs. BBB is funded under BioNEST scheme and controlled and operated by (RCB) Regional Centre for Biotechnology. For more information about BBB, please visit at- https://bbb.rcb.res.in/bio-entrepreneurship
Bsc bio nest bio incubator- healthcare, biotech start ups, bio entrepreneurshipGFFPL NewDelhi
Bio-incubation allows harnessing of the entrepreneurial potential of startups by providing access to infrastructure as well as mentoring and networking platforms that the start-ups could use during their fledgling days.
Over the last few years, a significant momentum has been seen in the startup ecosystem of the country especially in the field of Biotechnology. With a vision to foster the biotech innovation in the country. for more info Please visit http://bbb.rcb.res.in
Bsc bio nest bio incubator- healthcare, biotech start ups, bio entrepreneurshipGFFPL NewDelhi
Bio-incubation allows harnessing of the entrepreneurial potential of startups by providing access to infrastructure as well as mentoring and networking platforms that the start-ups could use during their fledgling days.
Over the last few years, a significant momentum has been seen in the startup ecosystem of the country especially in the field of Biotechnology. With a vision to foster the biotech innovation in the country. for more info Please visit http://bbb.rcb.res.in
How does agribusiness incubator help in technology commercialization and support the institute in achieving its mandates? Such a scenario calls for a change of perspective for the way institutes operates. The session will provide the institutes under NARS and others an overview on how business incubators help in not just technology transfer but also in generating revenues, protection of IPR, client interfacing and meeting their requirements and how agriculture can be viewed as a business entity.
In this issue: IQ — What is happening in the Middle East? Lebanon: an overview of Berytech visited within the BICBIC program by Al Urdonia Lil Ebda, Jordan. Palestine: the next year supporting the Palestinian ICT Incubator in Ramallah. QI — First feedback on the 2011 Quality process. QS — EC-BICs Experts on line: soon to come the “Ask the expert of the month” feature. QO — Showcase your BICs and your start-ups in the DIGIBIC Awards.
Navsarjan Turnkey solutions is established as a partnership firm in early phase of 2017 at Ahmedabad(Gujarat,India). We are having a team of experts, which contains homogeneous blend of Qualification & experience in their respective fields. We are having a team of experts, which contains homogeneous blend of Qualification & experience in their respective fields. Our Quality Policy is a distinct feature of our organization, which comprises of: Effective balance between Novelty, Quality & Economy, Commitment within timeline to provide trustworthy support, Systematic approach which extends itself towards client satisfaction, Meeting the quality standards, Navsarjan is accredited with ISO & CE certification.
The session will highlight how business incubators can provide a sustainable and effective lab-to-land platform for agricultural research institutions and aid in the development of agriculture and its allied sectors while generating revenue in the process. Case studies on business incubators under NIABI and other models across the world will also be featured.
The Business Intelligence Competency Center is a shared service offering that your organization can and should be leveraging for your BI needs. This deck, produced when I was running one of the largest consulting practices at Business Objects, dives into the concepts and detail surrounding the planning, development and roll-out of a BICC for a Fortune 2000 organization.
Presentation I put together while at Business Objects where I spearheaded the development of the Business Intelligence Competency Center practice and service offering.
Home to over 50% of the country’s Biotech companies.
Ÿ Bio-Ventures Fund and Bio Innovation Centre being established with state-of the-art laboratory facilities.
Ÿ Bangalore Bio Innovation Centre – 25 fully furnished labs to promote innovation driven R&D startups.
Ÿ 8 Biotech Finishing Schools offering post graduate diploma
Ÿ Karnataka has one of the highest R&D expenditure in India.
Ÿ In FY16, Government of Karnataka planned to raise USD7.34 million funds for research activities in
biotechnology.
Ÿ The state has built up considerable resources and talent pool that are well suited for the needs of the
industry.
We are contributing towards the development of the Indian Startup Ecosystem with a sector agnostic and innovation with a specific focus on supporting entrepreneurs in building software, fintech, agrotech, health tech, and SaaS products.
We Are Providing Technical Support, Business Toll & Funding Assistance For Businesses. Our Industry Experienced Mentor Will Help to grow.
Giving wings and roots to bright Indian startups by facilitating all-around growth, holding their hands through the initial phases of building their product, and providing access to the thriving Indian Startup Ecosystem with our industry contacts.
Visit us at, aic.shikshainfotech.com
How does agribusiness incubator help in technology commercialization and support the institute in achieving its mandates? Such a scenario calls for a change of perspective for the way institutes operates. The session will provide the institutes under NARS and others an overview on how business incubators help in not just technology transfer but also in generating revenues, protection of IPR, client interfacing and meeting their requirements and how agriculture can be viewed as a business entity.
In this issue: IQ — What is happening in the Middle East? Lebanon: an overview of Berytech visited within the BICBIC program by Al Urdonia Lil Ebda, Jordan. Palestine: the next year supporting the Palestinian ICT Incubator in Ramallah. QI — First feedback on the 2011 Quality process. QS — EC-BICs Experts on line: soon to come the “Ask the expert of the month” feature. QO — Showcase your BICs and your start-ups in the DIGIBIC Awards.
Navsarjan Turnkey solutions is established as a partnership firm in early phase of 2017 at Ahmedabad(Gujarat,India). We are having a team of experts, which contains homogeneous blend of Qualification & experience in their respective fields. We are having a team of experts, which contains homogeneous blend of Qualification & experience in their respective fields. Our Quality Policy is a distinct feature of our organization, which comprises of: Effective balance between Novelty, Quality & Economy, Commitment within timeline to provide trustworthy support, Systematic approach which extends itself towards client satisfaction, Meeting the quality standards, Navsarjan is accredited with ISO & CE certification.
The session will highlight how business incubators can provide a sustainable and effective lab-to-land platform for agricultural research institutions and aid in the development of agriculture and its allied sectors while generating revenue in the process. Case studies on business incubators under NIABI and other models across the world will also be featured.
The Business Intelligence Competency Center is a shared service offering that your organization can and should be leveraging for your BI needs. This deck, produced when I was running one of the largest consulting practices at Business Objects, dives into the concepts and detail surrounding the planning, development and roll-out of a BICC for a Fortune 2000 organization.
Presentation I put together while at Business Objects where I spearheaded the development of the Business Intelligence Competency Center practice and service offering.
Home to over 50% of the country’s Biotech companies.
Ÿ Bio-Ventures Fund and Bio Innovation Centre being established with state-of the-art laboratory facilities.
Ÿ Bangalore Bio Innovation Centre – 25 fully furnished labs to promote innovation driven R&D startups.
Ÿ 8 Biotech Finishing Schools offering post graduate diploma
Ÿ Karnataka has one of the highest R&D expenditure in India.
Ÿ In FY16, Government of Karnataka planned to raise USD7.34 million funds for research activities in
biotechnology.
Ÿ The state has built up considerable resources and talent pool that are well suited for the needs of the
industry.
We are contributing towards the development of the Indian Startup Ecosystem with a sector agnostic and innovation with a specific focus on supporting entrepreneurs in building software, fintech, agrotech, health tech, and SaaS products.
We Are Providing Technical Support, Business Toll & Funding Assistance For Businesses. Our Industry Experienced Mentor Will Help to grow.
Giving wings and roots to bright Indian startups by facilitating all-around growth, holding their hands through the initial phases of building their product, and providing access to the thriving Indian Startup Ecosystem with our industry contacts.
Visit us at, aic.shikshainfotech.com
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
2. INTRODUCTION
BBB is a fast growing centre for Bio Incubation located in
NCR Biotech Science Cluster in Faridabad.
Provides excellent incubation facilities & infrastructure area.
It is operated by Regional Centre for Technology which is
established by department of Biotechnology, govt. of India.
BBB is sponsored by BIRAC under the BioNEST
(Bioincubators Nurturing Entrepreneurship for Scaling
Technologies) scheme.
BBB aim is to support the growth & establishment of
biotechnology based startup companies.
3.
4. • BSC BioNEST Bio-Incubators gives young entrepreneurs a
better future opportunity
• BIRAC has supported around 50 bio-incubators with the help of
BioNEST
• It helps to convert innovative ideas into viable commercial
entities
• BBB provides excellent incubation facilities infrastructure,
spread across 35000 sq. ft. area
• Lab Space, Office Space, Professional Business Suites, Culture
Facility and Instrumentation facility are available at very
affordable cost
• Incubator gives globally competitive incubation services to
startups & young innovators related with Biotechnology or life
science domain