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Modular-Lab Standard
 Versatile equipment for research purposes




Modular-Lab Standard
Modular-Lab Standard is a fully auto-
mated system for radiochemical synthesis.




 Description                                                       Versatility
 Modular-Lab Standard has been specifically designed to allow      Available modules include a Peltier/Heater reaction system
 versatile radiochemical development and production. The           with solid-state temperature control from -40 °C to +150 °C/
 system enables custom synthesis processes to be assembled         220 °C, a wide variety of valve modules, instruments for tem-
 from a set of unit operation modules. The small, sealed and       perature, pressure and radiation detection, a compact semi-
 stainless steel modules are stacked and connected by process      preparative HPLC module, analytical HPLC, TLC modules, and
 tubing and by a single electrical cable. An intuitive graphical   many others. The intuitive user interface is easy to program
 interface is used to design and control the synthesis process.    by drag and drop of graphical symbols and adheres to today’s
                                                                   regulatory requirements. Parameters such as temperature,
 Advantages                                                        activity, UV detector readings, flow rates, or valve settings can
 Modular-Lab Standard’s unique modular approach combines           be monitored easily in one window. Reports containing all
 the speed and safety of a remote, fully automated system          relevant data and information are created automatically after
 with the flexibility to configure syntheses for novel tracers.    each run.
 Cleaning and sanitation routines can be programmed to take
 place between runs or overnight. With this multifunctionality,    Safety Functions
 Modular-Lab Standard supports research as well as routine         Reliable, automated synthesis, with remote monitoring pro-
 production. Disposable components such as valves, tubing,         vided as necessary through the graphical computer interface,
 cartridges and others are standard, off-the-shelf units and can   eliminates the need for hands-on operation and can signifi-
 be exchanged as needed for different applications. Modular-       cantly reduce radiation exposure to lab personnel.
 Lab Standard can be applied to a wide range of compounds
 and isotopes. The modules can be arranged to fit even very        Application Examples
 small hot cells.                                                  We offer a variety of chemical reactions including customized
                                                                   synthesis processes according to your needs, e.g. [18F]FEC,
                                                                   [18F]FDG, [18F]Fluoroethyltyrosine, [18F]Flumazenil, [18F]MISO,
                                                                   [11C]Choline, [11C]Methyl Iodide, [131I]MIBG, 68Ga-DOTA pep-
                                                                   tides, 64Cu applications, customized syntheses
Modular-Lab Standard
                              Technical Data
                              Main Unit

                              Dimensions of the Peltier Reaction         130 x 201 x 155 mm (W x D x H); Weight: 7.7 kg
                              Module (PRM)

                              Dimensions of the Vial Holder Module       130 x 130 x 76 mm (W x D x H); Weight: 2.0 kg
                              (VHM)

                              Dimensions of the Valve Modules            130 x 130 x 76 mm (W x D x H); Weight: 2.0 kg

                              Power supply                               115 V ~ 60 Hz or 230 V ~ 50 Hz

                              Power consumption                          Standard 480 W, 2 x bus 1,050 W, extension to 2,100 W possible

                              Environment temperature                    +10 °C to +40 °C

                              Environment humidity                       Max. 70 % rel.
                              Module Characteristics

                              Reaction module equipped with              Camera, stirrer, lift, activity detector, pressure detector and temperature sensor Sigradur
                                                                         vial (optional)

                              Reactor volume                             Variable from 1 – 24 ml

                              Cooling/heating                            Peltier elements or heating foil (-40 °C to +150 °C/ 220 °C)

                              Liquid transport                           Vacuum pump and/or pressure
                              Unit Control

                              Software                                   Modular-Lab Software

                              Interfaces                                 Ethernet
                              Please note: Modular-Lab Standard makes use of locally available, off-the-shelf tubing, connectors, vials and valves.




                               Eckert & Ziegler                                Your contact in USA & Canada:
                               Eurotope GmbH                                   Patrick J. Donahue

                                                                               P.O. Box 128
7131-0001 /Rev.10 / 08.2011




                               Robert-Rössle-Strasse 10
                               13125 Berlin                                    Hopkinton, MA 01748
                               Germany                                         USA
                               Phone:     +49 (0) 30 94 10 84-197              Phone:     +1 508 497 0060
                               Fax:       +49 (0) 30 94 10 84-470              Fax:       +1 508 497 0061

                               eurotope@ezag.de                                eurotope@ezag.com
                               www.ezag.com/radiopharma                        www.ezag.com/radiopharma

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7131 0001 fact sheet modular-lab rev.10

  • 1. Modular-Lab Standard Versatile equipment for research purposes Modular-Lab Standard Modular-Lab Standard is a fully auto- mated system for radiochemical synthesis. Description Versatility Modular-Lab Standard has been specifically designed to allow Available modules include a Peltier/Heater reaction system versatile radiochemical development and production. The with solid-state temperature control from -40 °C to +150 °C/ system enables custom synthesis processes to be assembled 220 °C, a wide variety of valve modules, instruments for tem- from a set of unit operation modules. The small, sealed and perature, pressure and radiation detection, a compact semi- stainless steel modules are stacked and connected by process preparative HPLC module, analytical HPLC, TLC modules, and tubing and by a single electrical cable. An intuitive graphical many others. The intuitive user interface is easy to program interface is used to design and control the synthesis process. by drag and drop of graphical symbols and adheres to today’s regulatory requirements. Parameters such as temperature, Advantages activity, UV detector readings, flow rates, or valve settings can Modular-Lab Standard’s unique modular approach combines be monitored easily in one window. Reports containing all the speed and safety of a remote, fully automated system relevant data and information are created automatically after with the flexibility to configure syntheses for novel tracers. each run. Cleaning and sanitation routines can be programmed to take place between runs or overnight. With this multifunctionality, Safety Functions Modular-Lab Standard supports research as well as routine Reliable, automated synthesis, with remote monitoring pro- production. Disposable components such as valves, tubing, vided as necessary through the graphical computer interface, cartridges and others are standard, off-the-shelf units and can eliminates the need for hands-on operation and can signifi- be exchanged as needed for different applications. Modular- cantly reduce radiation exposure to lab personnel. Lab Standard can be applied to a wide range of compounds and isotopes. The modules can be arranged to fit even very Application Examples small hot cells. We offer a variety of chemical reactions including customized synthesis processes according to your needs, e.g. [18F]FEC, [18F]FDG, [18F]Fluoroethyltyrosine, [18F]Flumazenil, [18F]MISO, [11C]Choline, [11C]Methyl Iodide, [131I]MIBG, 68Ga-DOTA pep- tides, 64Cu applications, customized syntheses
  • 2. Modular-Lab Standard Technical Data Main Unit Dimensions of the Peltier Reaction 130 x 201 x 155 mm (W x D x H); Weight: 7.7 kg Module (PRM) Dimensions of the Vial Holder Module 130 x 130 x 76 mm (W x D x H); Weight: 2.0 kg (VHM) Dimensions of the Valve Modules 130 x 130 x 76 mm (W x D x H); Weight: 2.0 kg Power supply 115 V ~ 60 Hz or 230 V ~ 50 Hz Power consumption Standard 480 W, 2 x bus 1,050 W, extension to 2,100 W possible Environment temperature +10 °C to +40 °C Environment humidity Max. 70 % rel. Module Characteristics Reaction module equipped with Camera, stirrer, lift, activity detector, pressure detector and temperature sensor Sigradur vial (optional) Reactor volume Variable from 1 – 24 ml Cooling/heating Peltier elements or heating foil (-40 °C to +150 °C/ 220 °C) Liquid transport Vacuum pump and/or pressure Unit Control Software Modular-Lab Software Interfaces Ethernet Please note: Modular-Lab Standard makes use of locally available, off-the-shelf tubing, connectors, vials and valves. Eckert & Ziegler Your contact in USA & Canada: Eurotope GmbH Patrick J. Donahue P.O. Box 128 7131-0001 /Rev.10 / 08.2011 Robert-Rössle-Strasse 10 13125 Berlin Hopkinton, MA 01748 Germany USA Phone: +49 (0) 30 94 10 84-197 Phone: +1 508 497 0060 Fax: +49 (0) 30 94 10 84-470 Fax: +1 508 497 0061 eurotope@ezag.de eurotope@ezag.com www.ezag.com/radiopharma www.ezag.com/radiopharma