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The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise boosts blood flow, releases endorphins, and promotes changes in the brain which help enhance one's emotional well-being and mental clarity.
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BIOCHEMISTRY ПМГИМУ - 3.3 Regulation of Gene Expression (plus drag and drop)
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
PA/IVS - Dr. Julius King Kwedhi
Pulmonary atresia with intact ventricular septum (PA/IVS) is a rare congenital heart defect where the pulmonary valve is blocked, preventing blood flow to the lungs. It is characterized by an underdeveloped right ventricle and connections between the right ventricle and coronary arteries. Newborns present with cyanosis and rely on a patent ductus arteriosus for pulmonary blood flow. Without intervention, most infants will die within the first few months of life. Treatment involves surgical procedures like the Blalock-Taussig shunt, bidirectional Glenn procedure, and Fontan operation to redirect blood flow to the lungs without using the right ventricle.
Leukemia in Pediatrics - Dr. Julius King Kwedhi
Definition
A group of malignant diseases in which genetic abnormalities in a hematopoietic cell give rise to an unregulated clonal proliferation of cells
The progeny of these cells have a growth advantage over normal cellular elements, with an increased rate of proliferation & a decreased rate of spontaneous apoptosis
Disruption of normal marrow function, leading to marrow failure
Hypertrophic Cardiomyopathy - Dr. Julius King Kwedhi
Case:
Anamnesis:
Patient was diagnosed with pneumonia in 2016
Patient has been examined by infectious diseases specialist
Was diagnosed with sarcoidosis in 2017 after radiologic exam last month
Previous lung auscultation revealed crepitation
He was treated with corticosteroids, which helped eliminate crepitation
He was treated with prednisolon 30-35 mg
Hemolytic Anemia - Dr. Julius King Kwedhi - Pediatrics
Definition:
Premature Destruction of Red Blood Cells, either intramuscularly or extravascularly, leading to a shortened red cell survival time.
Causes:
Premature Destruction of Red Blood Cells, either intramuscularly or extravascularly, leading to a shortened red cell survival time.
Genital Tract Infections - Dr. Julius King Kwedhi
Differential Diagnoses of Acute and Chronic Lower Abdominal Pain
Endometriosis
Ovarian cysts accident (torsion, haemorrhage, rupture)
Appendicitis
Cystitis
Diverticulitis
Ectopic Pregnancy
Tumors
Trapped Ovarian Syndrome
Mittelschmerz
Primary Dysmenorrhea
Pelvic Inflammatory Disease..., etc
Breast diseases - Dr. Julius King Kwedhi
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History: Patient, Family, Current Breast complaint
Physical Examination: Inspection, Palpation, Lymph nodes
Diagnosis & Imaging: US, Mammography, MRI, CT, FNAC, Biopsy
Treatment: Hormonal, Antibiotics, Surgical, Chemotherapy
Ectopic Pregnancy - Dr. Julius King Kwedhi
Introduction
Lead to tubal rupture;
massive intra-abdominal hemorrhage —> death;
Tubal damage —> poor reproductive outcome;
It is the leading pregnancy-related cause of death in the first trimester.
With reliable serum pregnancy tests and vaginal ultrasound, early detection and treatment of an ectopic pregnancy is possible.
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BIOCHEMISTRY ПМГИМУ - 3.3 Regulation of Gene Expression (plus drag and drop)
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
PA/IVS - Dr. Julius King Kwedhi
Pulmonary atresia with intact ventricular septum (PA/IVS) is a rare congenital heart defect where the pulmonary valve is blocked, preventing blood flow to the lungs. It is characterized by an underdeveloped right ventricle and connections between the right ventricle and coronary arteries. Newborns present with cyanosis and rely on a patent ductus arteriosus for pulmonary blood flow. Without intervention, most infants will die within the first few months of life. Treatment involves surgical procedures like the Blalock-Taussig shunt, bidirectional Glenn procedure, and Fontan operation to redirect blood flow to the lungs without using the right ventricle.
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Definition
A group of malignant diseases in which genetic abnormalities in a hematopoietic cell give rise to an unregulated clonal proliferation of cells
The progeny of these cells have a growth advantage over normal cellular elements, with an increased rate of proliferation & a decreased rate of spontaneous apoptosis
Disruption of normal marrow function, leading to marrow failure
Hypertrophic Cardiomyopathy - Dr. Julius King Kwedhi
Case:
Anamnesis:
Patient was diagnosed with pneumonia in 2016
Patient has been examined by infectious diseases specialist
Was diagnosed with sarcoidosis in 2017 after radiologic exam last month
Previous lung auscultation revealed crepitation
He was treated with corticosteroids, which helped eliminate crepitation
He was treated with prednisolon 30-35 mg
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Premature Destruction of Red Blood Cells, either intramuscularly or extravascularly, leading to a shortened red cell survival time.
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Premature Destruction of Red Blood Cells, either intramuscularly or extravascularly, leading to a shortened red cell survival time.
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Endometriosis
Ovarian cysts accident (torsion, haemorrhage, rupture)
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Trapped Ovarian Syndrome
Mittelschmerz
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Introduction
Lead to tubal rupture;
massive intra-abdominal hemorrhage —> death;
Tubal damage —> poor reproductive outcome;
It is the leading pregnancy-related cause of death in the first trimester.
With reliable serum pregnancy tests and vaginal ultrasound, early detection and treatment of an ectopic pregnancy is possible.
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Tuberculous peritonitis
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Acid-fast, rod shaped
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The document discusses the benefits of exercise for both physical and mental health. Regular exercise can improve cardiovascular health, reduce symptoms of depression and anxiety, enhance mood, and boost brain function. Staying physically active helps fight diseases and conditions while improving quality of life.
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The document discusses the benefits of meditation for reducing stress and anxiety. Regular meditation practice can help calm the mind and body by lowering heart rate and blood pressure. Studies have shown that meditating for just 10-20 minutes per day can have significant positive impacts on both mental and physical health over time.
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Notes used to prepare for class discussions as well as for the Colloquium tests following the lessons covered in each of these pdf notes.
These notes are for the First Colloquium.
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1. Nucleic acids are made of nucleotides, which consist of a nucleoside (a nitrogenous base linked to a 5-carbon sugar) and one or more phosphate groups. The bases are either pyrimidines or purines.
2. DNA contains the bases adenine, guanine, cytosine, and thymine, while RNA contains adenine, guanine, cytosine, and uracil instead of thymine.
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Nervus Ophthalmicus - Sensory
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The word "ataxia", comes from the Greek word, "a taxis" meaning "without order or incoordination". The word ataxia means without coordination. (http://www.ataxia.org/learn/ataxia-diagnosis.aspx)
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Modern aspercts of preventiv medicine
The document discusses mortality trends, causes of death, and prevention of non-communicable diseases. It notes that diseases of the circulatory system and cancer are becoming the leading causes of death globally and in Russia. Prevention is highlighted as the most cost-effective approach, with measures to address diseases of the circulatory system and cancer able to increase life expectancy by 10 and 8 years respectively. The document outlines principles of health promotion, types of prevention including primary, secondary and tertiary, and Russia's federal program to promote healthy lifestyles and prevent non-communicable diseases from 2013-2017 with the goal of increasing life expectancy.
Introduction to ph 11.01.2016
Introduction. History of Department for Public
Health and Health Care I. Sechenov`s FMSMU
Part I CONCEPT OF HEALTH.
Determinants of Health. Globalization and Health.
Model of Disease causation theories.
Part II PUBLIC HEALTH. History of public health.
Definition of public health. Major disciplines in
public health.
Part III HEALTH AND DEVELOPMENT
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This document discusses principles of hygiene and health protection for children and adolescents. It outlines several key laws of growth and development, including unevenness of growth, gender differences, environmental and genetic influences, and sensitive periods. Physical development indicators and criteria for evaluating biological age are provided. The document also establishes health groups based on presence of diseases and functional status to determine needed medical supervision.
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Lecture notes created and handed out to her students in Physiology class by Professor E.G. Ionkina, of the Physiology Department, First Moscow State Medical University I.M. Sechenov, Moscow, Russia.
Notes used to prepare for class discussions as well as for the Colloquium tests following the lessons covered in each of these pdf notes.
These notes are for the First Colloquium.
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1. Nucleic acids are made of nucleotides, which consist of a nucleoside (a nitrogenous base linked to a 5-carbon sugar) and one or more phosphate groups. The bases are either pyrimidines or purines.
2. DNA contains the bases adenine, guanine, cytosine, and thymine, while RNA contains adenine, guanine, cytosine, and uracil instead of thymine.
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Gastrointestinal Infections
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These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
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Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
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Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
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