Medication use safety is an important healthcare issue that can impact patient health. Adverse effects from unsafe medication use lead to over 1 million emergency room visits and 350,000 hospitalizations annually in the US. The elderly are particularly at risk. Pharmacists play a key role in medication safety by ensuring appropriate prescribing, dispensing, administration, lab monitoring, and adherence. They educate patients on safe medication use, review dosing and side effects, evaluate appropriateness and safety, and improve adherence.
Pharmaceutical care concepts - clinical pharmacy ShaistaSumayya
The pharmaceutical care is defined as “the direct, responsible provision of medication-related care for the purpose of achieving definite outcomes that improve a patient’s quality of life.”
Pharmaceutical care involves the process through which a pharmacist cooperates with a patient and other professional in designing , implementation, and monitoring a therapeutic plan that will produce specific therapeutic outcomes for the patient
Clinical pharmacy may be defined as the science and practice of rationale use of
medications, where the pharmacists are more oriented towards the patient care
rationalizing medication therapy promoting health , wellness of people.
It is the modern and extended field of pharmacy.
“ The discipline that embodies the application and development (by pharmacist) of
scientific principles of pharmacology, toxicology, therapeutics, and clinical pharmacokinetics, pharmacoeconomics, pharmacogenomics and other allied
sciences for the care of patients”.
Introduction: Medication adherence is defined by the World Health Organisation as “The degree to which the person's behaviour corresponds with the agreed recommendations from a health care provider
Factor Affecting Non-Adherance:Poor adherence or non-adherence to medical treatment severely compromises patient outcomes and increases patient mortality.
Non-adherence is a very common phenomenon in all patients with drug-taking behaviour.
The complexity of adherence is the result of an interplay of a range of factors, including patient views and attributes, illness characteristics, social contexts, access, and service issues.
Non-adherence: Non-adherence is the failure or refusal to comply with advice and can imply disobedience on the part of patient
5 step Factors: Social/economic and Economic Factors
Provider-patient/health care system factors
Condition-related factors
Therapy-related factors
Patient-related factors
Behavioural Factors:
Life style (smoking, alcohol, coffee use) Psychological and personality factors: anxiety, depression, coping style
Biological factors:
Gender, age, and genetic predisposition
Social and cultural factors:
Educational level, living situation, price of medication, policies.
Information Factors:
Have you received enough information? Satisfaction with the last visit?
Awareness factors:
Severity of the complaints (Baseline) quality of life,
Locus of control about patient adherence:
internal and external, stability and control about the cause of the complaints: internal and external, stability and controllability.
Stages to Overcome This Barrier
An Essential Drug List, also known as a core drug list or medication list, is a carefully selected inventory of medications that are deemed essential for addressing the most prevalent health conditions within a specific population or country. It serves as a key component of national drug policies and pharmaceutical programs, ensuring the availability, accessibility, and affordability of essential medicines. The list is typically developed based on rigorous criteria, taking into consideration the medications' safety, efficacy, cost-effectiveness, and suitability for primary healthcare settings.
Rational Drug Therapy refers to the systematic and evidence-based approach to prescribing medications, aiming to maximize therapeutic benefits while minimizing the risk of adverse effects. It involves following established therapeutic guidelines and clinical protocols to ensure that medications are prescribed in a manner that is appropriate for the patient's condition, taking into account factors such as age, weight, co-existing conditions, drug interactions, and individual response. Rational drug therapy promotes the use of medications based on sound scientific evidence, emphasizing the principles of efficacy, safety, and cost-effectiveness to optimize patient outcomes and improve overall healthcare quality.
Pharmaceutical care concepts - clinical pharmacy ShaistaSumayya
The pharmaceutical care is defined as “the direct, responsible provision of medication-related care for the purpose of achieving definite outcomes that improve a patient’s quality of life.”
Pharmaceutical care involves the process through which a pharmacist cooperates with a patient and other professional in designing , implementation, and monitoring a therapeutic plan that will produce specific therapeutic outcomes for the patient
Clinical pharmacy may be defined as the science and practice of rationale use of
medications, where the pharmacists are more oriented towards the patient care
rationalizing medication therapy promoting health , wellness of people.
It is the modern and extended field of pharmacy.
“ The discipline that embodies the application and development (by pharmacist) of
scientific principles of pharmacology, toxicology, therapeutics, and clinical pharmacokinetics, pharmacoeconomics, pharmacogenomics and other allied
sciences for the care of patients”.
Introduction: Medication adherence is defined by the World Health Organisation as “The degree to which the person's behaviour corresponds with the agreed recommendations from a health care provider
Factor Affecting Non-Adherance:Poor adherence or non-adherence to medical treatment severely compromises patient outcomes and increases patient mortality.
Non-adherence is a very common phenomenon in all patients with drug-taking behaviour.
The complexity of adherence is the result of an interplay of a range of factors, including patient views and attributes, illness characteristics, social contexts, access, and service issues.
Non-adherence: Non-adherence is the failure or refusal to comply with advice and can imply disobedience on the part of patient
5 step Factors: Social/economic and Economic Factors
Provider-patient/health care system factors
Condition-related factors
Therapy-related factors
Patient-related factors
Behavioural Factors:
Life style (smoking, alcohol, coffee use) Psychological and personality factors: anxiety, depression, coping style
Biological factors:
Gender, age, and genetic predisposition
Social and cultural factors:
Educational level, living situation, price of medication, policies.
Information Factors:
Have you received enough information? Satisfaction with the last visit?
Awareness factors:
Severity of the complaints (Baseline) quality of life,
Locus of control about patient adherence:
internal and external, stability and control about the cause of the complaints: internal and external, stability and controllability.
Stages to Overcome This Barrier
An Essential Drug List, also known as a core drug list or medication list, is a carefully selected inventory of medications that are deemed essential for addressing the most prevalent health conditions within a specific population or country. It serves as a key component of national drug policies and pharmaceutical programs, ensuring the availability, accessibility, and affordability of essential medicines. The list is typically developed based on rigorous criteria, taking into consideration the medications' safety, efficacy, cost-effectiveness, and suitability for primary healthcare settings.
Rational Drug Therapy refers to the systematic and evidence-based approach to prescribing medications, aiming to maximize therapeutic benefits while minimizing the risk of adverse effects. It involves following established therapeutic guidelines and clinical protocols to ensure that medications are prescribed in a manner that is appropriate for the patient's condition, taking into account factors such as age, weight, co-existing conditions, drug interactions, and individual response. Rational drug therapy promotes the use of medications based on sound scientific evidence, emphasizing the principles of efficacy, safety, and cost-effectiveness to optimize patient outcomes and improve overall healthcare quality.
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2. Medication use safety is an important aspect of the healthcare
delivery system to consider in all patients as it can affect the
patient’s overall health at home and within the healthcare system.
Adverse effects often result from unsafe medication use, leading
to more than one million visits to the emergency room and
350,000 hospitalizations on an annual basis.
1 Billions of dollars are spent addressing ADEs, with the elderly
population particularly at risk.
3. Prescribing
1-Choosing an appropriate medication for a given clinical
situation, taking individual patient factors into account, indictions,
contraindications, allergies, pregnancy, comorbidities
2-Selecting the administration route, dose , time and regiem
3-Communicating details of the plan to the patient or next of kin
4-Documentation:legible,complete,no ambiguity
Right drug, Right dose, Right route, Right time and Right patient
4. Provide the patient with the following information
1-Name, purpose and action of the medication
2-Dose, route and administration schedule
3-Special instructions, directions and precautions
4-Common side effects and interactions
5-How the medication will be monitored
5. Wrong monitoring
1-Lack of monitoring for side effects
2-Drug not ceased if not working , or course completed
3-Drug ceased before course completed
4-Drug levels not measured or not followed up
5-Communication failure
6. Causes of medication errors
1-Inadequate information about the patient
2-Inadequate information about the drug
3-Communication and teamwork failure
4-Unclear, absent or look-alike drug labels and packages and
confusing , look-alike or sound-alike drug names
5-Unsafe drug standardizations, storage and distribution
6-Nonstandard or unsafe medication delivery devices
7-Environmental factors and staffing patterns that does not
support safety
7. 8-Inadequate patient education about medication and medication
errors
9-lack of a supportive culture of safety , failure to learn from
mistakes and absent error-reduction strategies
8. Staff factors in medication error
1-Inexperience
2-Rushing
3-Doing two things at once
4-Interruptions
5-Fatigue, boredom
6-Failure to double-check habit
7-Poor team work and/or communication between colleagues
8-Reluctance to use memory aids
9-Inadequate education, supervision and competency validation
9. Causes of adverse effects
Reasons for this include
1-Physiologic changes
2-Health literacy barriers
3-Health disparities
4-Polypharmacy
5-Nonadherence.
Nonadherence can be intentional or unintentional and affected by
medication efficacy, side effects, perceptions of one’s health or
illness, or cultural beliefs, cost, availability
10. 6-The addition of harmful substances (bacteria-laced water,
paint, floor wax, boric acid, powdered cement, and antifreeze),
7-Incorrect active ingredient in the product
8-Wrong concentration or dose
9-Internet pharmacies: Many companies claim that the
medications are being manufactured in a very well known country
, but this has been proven to be false.
They often provide medications that are not approved by the
ministry of health.
11. physical impairments can also result in medication nonadherence
and ADEs. Impairments can include, but are not limited to,
dexterity, vision, mental status, and hearing.
12. The Medication Appropriateness Index (MAI) is a tool that can be
used to prevent ADEs; this tool consists of 10 questions that a
pharmacist may ask regarding each drug a patient is taking.
The questionnaire assesses a medication’s indication,
effectiveness, dose, directions for use, administration,
interactions, duration of use, and cost.
Based on a score ranging between 0 and 18, the MAI provides a
final rating of appropriateness:
appropriate, marginally appropriate, or inappropriate.
13. The role of pharmacists
Pharmacists are uniquely positioned to
1-Ensure access to medication
a-evaluate ability to pay for medication
b-explore alternative medication
c-explore alternative means of payment
2-Supply medication information
a-educate patient on safe and effective medication use
b-reviewing proper dosing
14. c-Providing information about adverse effects, interactions and
common medication errors
3-Evaluate medication appropriateness: assess medication
appropriateness, effectiveness and safety for each individual
patient.
4-Improve medication adherence: suggesting changes in dosing
or additional therapies that improve patient adherence to the
medication
5-Provide health and wellness services:deliver direct health
services
15. 6-Medication management: review of full medication regiem to
ensure medications work well together and avoid problems like
interactions
7-Assess health status
a-Determine current patient status and medication effectiveness
b-Provide guidance regarding medication therapy
8-Coordinating care transitions: reviewing the list of drugs in use
and discovering any interaction
16. Pharmacists are the key professionals positioned to address
medication safety by ensuring
1-Appropriate prescribing
2-Appropriate dispensing
3-Appropriate administration
4-Lab monitoring, and
5-Adherence