This document discusses genetic genealogy and DNA testing. It begins with definitions of genetic genealogy and traditional genealogy research. It then provides details on human genetics such as the number of chromosomes, genes, and single nucleotide polymorphisms (SNPs). The document lists some major DNA testing companies and notes that the consumer genomics market is growing rapidly. It discusses factors to consider when choosing a DNA testing company. The remainder provides information on genetic genealogy projects and the Gene by Gene laboratory.
The document discusses recent findings in ancient DNA research. It summarizes a 2014 Nature article that analyzed ancient human genomes from present-day Europeans and suggested three ancestral populations. It also lists 27 other relevant published ancient DNA studies from the past few years. Key criteria for evaluating the reliability of ancient DNA analyses are discussed, such as the journal and researchers involved, sample handling, contamination controls, and consistency of results.
Open human genome data - presentation at the annual TKT/CLIDP doctoral programme symposium 2016 "Open up! – Open Data and Open Access" of the University of Turku.
Phylogenetic analyses of two gene sequences from Fusarium species support the monophyly of a clade comprising 20 species complexes and 9 monotypic lineages of Fusarium. This clade, termed the terminal Fusarium clade (TFC), is estimated to have originated in the middle Cretaceous period around 91 million years ago. Analysis of secondary metabolite genes in several Fusarium genome sequences showed that many mycotoxins and other compounds originated earlier in the evolution of the TFC. Dating of plant-associated species complexes suggests their evolution may have coincided with angiosperm diversification during the Miocene.
This document discusses a bioinformatic analysis that identified potential dioxin and dibenzofuran degrading bacteria. The analysis gathered nucleotide sequences for genes known to be involved in degradation, like bph, car, cat, and nah genes. It performed BLAST searches to find similar sequences in other organisms and aligned the sequences. Phylogenetic trees were generated to illustrate evolutionary relationships between species and identify previously undocumented genes that may also degrade dioxins and dibenzofurans. Several Pseudomonas, Rhodococcus, Sphingomonas, and other bacterial species were identified as possessing homologs of known degradative genes.
Overview of the approaches I co-developed to reconstruct species trees and gene trees, in the presence of gene duplications, losses and transfers, or incomplete lineage sorting. Includes Phyldog, ALE, MP-EST*, RevBayes.
Phylogenetic and Phylogenomic Approaches to the Study of Microbes and Microbi...Jonathan Eisen
The document discusses Jonathan Eisen's work as a microbiology professor at UC Davis. It provides an overview of his research topics, which include microbial phylogenomics and evolvability, phylogenetic methods and tools, and using phylogenomics to study microbial communities and interactions between microbes and hosts under stress. The document also acknowledges collaborators and funding sources for Eisen's research over the years.
The document discusses recent findings in ancient DNA research. It summarizes a 2014 Nature article that analyzed ancient human genomes from present-day Europeans and suggested three ancestral populations. It also lists 27 other relevant published ancient DNA studies from the past few years. Key criteria for evaluating the reliability of ancient DNA analyses are discussed, such as the journal and researchers involved, sample handling, contamination controls, and consistency of results.
Open human genome data - presentation at the annual TKT/CLIDP doctoral programme symposium 2016 "Open up! – Open Data and Open Access" of the University of Turku.
Phylogenetic analyses of two gene sequences from Fusarium species support the monophyly of a clade comprising 20 species complexes and 9 monotypic lineages of Fusarium. This clade, termed the terminal Fusarium clade (TFC), is estimated to have originated in the middle Cretaceous period around 91 million years ago. Analysis of secondary metabolite genes in several Fusarium genome sequences showed that many mycotoxins and other compounds originated earlier in the evolution of the TFC. Dating of plant-associated species complexes suggests their evolution may have coincided with angiosperm diversification during the Miocene.
This document discusses a bioinformatic analysis that identified potential dioxin and dibenzofuran degrading bacteria. The analysis gathered nucleotide sequences for genes known to be involved in degradation, like bph, car, cat, and nah genes. It performed BLAST searches to find similar sequences in other organisms and aligned the sequences. Phylogenetic trees were generated to illustrate evolutionary relationships between species and identify previously undocumented genes that may also degrade dioxins and dibenzofurans. Several Pseudomonas, Rhodococcus, Sphingomonas, and other bacterial species were identified as possessing homologs of known degradative genes.
Overview of the approaches I co-developed to reconstruct species trees and gene trees, in the presence of gene duplications, losses and transfers, or incomplete lineage sorting. Includes Phyldog, ALE, MP-EST*, RevBayes.
Phylogenetic and Phylogenomic Approaches to the Study of Microbes and Microbi...Jonathan Eisen
The document discusses Jonathan Eisen's work as a microbiology professor at UC Davis. It provides an overview of his research topics, which include microbial phylogenomics and evolvability, phylogenetic methods and tools, and using phylogenomics to study microbial communities and interactions between microbes and hosts under stress. The document also acknowledges collaborators and funding sources for Eisen's research over the years.
This curriculum vitae summarizes the educational and professional experience of Gang Zhang. It outlines his PhD in life sciences from Shandong Normal University in China and postdoctoral research at the University of Toronto. Zhang has over 15 years of experience in areas like genome editing, gene engineering, cellular and developmental biology, and reproduction biology. He has published over 20 papers as first author or co-author on related topics. The CV lists his supervision and research experience, awards, editorial roles, and invited speaking engagements at universities in Canada, US and China.
This document discusses the potential for remote delivery of genetic counseling through telemedicine. It notes that demand for genetic counselors is outpacing supply. The document proposes building a comprehensive platform to enable remote genetic testing, counseling, and follow-up. Key components would include educational tools and counseling sessions delivered virtually. Over time, the goal is to develop more automated solutions using advanced algorithms. This could help address the shortage of genetic counselors and improve access to genetic testing and counseling services.
This document describes the principles, organization, and operation of a DNA bank established by the Department of Veterans Affairs Cooperative Studies Program. The DNA bank was created to facilitate genetic research using DNA samples collected from participants in clinical trials and studies. Key aspects discussed include obtaining informed consent from participants, ensuring privacy and confidentiality, resolving issues around ownership and future use of genetic material, and providing an infrastructure to support linking genetic and clinical data. The DNA bank is intended to be a shared resource that can support future genetic research across multiple clinical studies in different disease areas over time.
To date, the Registry has epidemiology and quality-of-life data from 11,180 self-registered patients with 4,196
well-characterized samples of DNA, lymphoblast lines, and sera for future research studies.
This document provides a summary of Fengkun Du's career and qualifications. It outlines his experience as a microbiologist with over 7 years working in proteomic research and the wastewater industry. It also details his education including a PhD in Applied and Environmental Microbiology from Georgia State University and collaborations with various universities. His skills include protein purification techniques, cell culture, fermentation, microarray data analysis and more.
The Kidney Research Institute held its inaugural Patient Advisory Committee meeting in February 2016. The committee, composed of eight transplant recipients, provided feedback on ongoing research projects and suggested focusing on studies that directly impact patient care. Additionally, Dr. Matthew Rivara was selected for a career development program focused on assessing kidney disease symptoms. Dr. Benjamin Freedman received funding to study stem cells as models for polycystic kidney disease and potential kidney replacements. Researchers are also working on a "kidney-on-a-chip" device to test new drugs in engineered kidney tissue.
This curriculum vitae summarizes the educational and professional experience of Gang Zhang. It outlines his PhD in life sciences from Shandong Normal University in China and postdoctoral research at the University of Toronto. Zhang has over 15 years of experience in areas like genome editing, gene engineering, cellular and developmental biology, and reproduction biology. He has published over 20 papers as first author or co-author on related topics. The CV lists his supervision and research experience, awards, editorial roles, and invited speaking engagements at universities in Canada, US and China.
This document discusses the potential for remote delivery of genetic counseling through telemedicine. It notes that demand for genetic counselors is outpacing supply. The document proposes building a comprehensive platform to enable remote genetic testing, counseling, and follow-up. Key components would include educational tools and counseling sessions delivered virtually. Over time, the goal is to develop more automated solutions using advanced algorithms. This could help address the shortage of genetic counselors and improve access to genetic testing and counseling services.
This document describes the principles, organization, and operation of a DNA bank established by the Department of Veterans Affairs Cooperative Studies Program. The DNA bank was created to facilitate genetic research using DNA samples collected from participants in clinical trials and studies. Key aspects discussed include obtaining informed consent from participants, ensuring privacy and confidentiality, resolving issues around ownership and future use of genetic material, and providing an infrastructure to support linking genetic and clinical data. The DNA bank is intended to be a shared resource that can support future genetic research across multiple clinical studies in different disease areas over time.
To date, the Registry has epidemiology and quality-of-life data from 11,180 self-registered patients with 4,196
well-characterized samples of DNA, lymphoblast lines, and sera for future research studies.
This document provides a summary of Fengkun Du's career and qualifications. It outlines his experience as a microbiologist with over 7 years working in proteomic research and the wastewater industry. It also details his education including a PhD in Applied and Environmental Microbiology from Georgia State University and collaborations with various universities. His skills include protein purification techniques, cell culture, fermentation, microarray data analysis and more.
The Kidney Research Institute held its inaugural Patient Advisory Committee meeting in February 2016. The committee, composed of eight transplant recipients, provided feedback on ongoing research projects and suggested focusing on studies that directly impact patient care. Additionally, Dr. Matthew Rivara was selected for a career development program focused on assessing kidney disease symptoms. Dr. Benjamin Freedman received funding to study stem cells as models for polycystic kidney disease and potential kidney replacements. Researchers are also working on a "kidney-on-a-chip" device to test new drugs in engineered kidney tissue.
Human Genetics and Craniofacial DevelopmentAlwaleed Fahad
This document discusses the evolution of human genetic studies of craniofacial disorders such as orofacial clefts. It describes how studies have progressed from descriptive family studies and Mendelian genetics in the early 20th century to modern genome-wide association studies and genomic sequencing. Key developments include the ability to collect and analyze DNA from families to study linkage, perform candidate gene studies and genome-wide linkage analyses. The advent of widespread genomic sequencing in 2000 enabled unbiased genome-wide association studies to identify risk loci rather than genes. One example described used a GWAS to identify multiple gene loci associated with the age of emergence of primary teeth.
ENC 1101Assignment 2Topic Selection Genetics 1. Use the .docxchristinemaritza
ENC 1101
Assignment: 2
Topic Selection: Genetics
1. Use the two articles provided
a. Is it OK to make babies from 3 parents' DNA?
b. Oxford Professor Says Genetically Altering Unborn Babies Personalities A Moral Obligation
2. Please include two sources from the library or the library databases
Research/Source Evaluation Paper:
A research paper is the culmination and final product of an involved process of research, critical thinking, source evaluation, organization, and composition. Source Evaluation is needed to scrutinize and analyze the given sources on their substance and academic validity.
Assignment:
Students will submit an outline and compose a three-page (research/evaluation) paper.
Instructions:
Make sure that your paper has:
•
A clear, concise, and defined thesis statement that occurs in the first portion of the paper.
•
Clear and logical transitions between the introduction, body, and conclusion.
•
Body paragraphs that include evidential support.
•
Evidential support (whether factual, logical, statistical, or anecdotal).
•
A conclusion that does not simply restate the thesis but readdresses it in light of the evidence provided.
Due Date:
Your three-page paper is due March 15. When typing your paper, please be sure to double-space and to use the standard 12-point font in either Times New Roman or Calibri. Follow MLA research guidelines. Be sure to also include a Works Cited.
Oxford Professor Says Genetically Altering Unborn Babies Personalities A Moral Obligation
By WakingTimes January 22, 2013
Aaron Jackson, Guest Writer
Waking Times
Genetically screening our offspring to make them better people is just “responsible parenting”, claims an eminent Oxford academic, The Telegraph reports.
Professor Julian Savulescu, editor-in-chief of the Journal of Medical Ethics, said that creating so-called designer babies could be considered a “moral obligation” as it makes them grow up into “ethically better children”, this based on a few genetic links to ‘personality disorders’.
He said that we should actively give parents the choice to screen out personality flaws in their children as it meant they were then less likely to “harm themselves and others”.
Studies show that the child’s upbringing, including parenthood and schooling methods are the root causes of many ‘personality flaws’. Other studies give strong evidence that nutrition, meditation and exercise greatly influence behavioural patterns and emotional well-being. This entire theory is also blind to the side effects of many medicines, vaccines, food additives and (some) GMO foods that have been proven to affect psychological behaviour, and this isn’t even touching on the possible beneficial use of marijuana and other substances for those with undesired personality traits.
“Surely trying to ensure that your children have the best, or a good enough, opportunity for a great life is responsible parenting?” wrote Prof Savulescu, the Uehiro Professor in practical ethics.
ENC 1101Assignment 2Topic Selection Genetics 1. Use the .docxgidmanmary
ENC 1101
Assignment: 2
Topic Selection: Genetics
1. Use the two articles provided
a. Is it OK to make babies from 3 parents' DNA?
b. Oxford Professor Says Genetically Altering Unborn Babies Personalities A Moral Obligation
2. Please include two sources from the library or the library databases
Research/Source Evaluation Paper:
A research paper is the culmination and final product of an involved process of research, critical thinking, source evaluation, organization, and composition. Source Evaluation is needed to scrutinize and analyze the given sources on their substance and academic validity.
Assignment:
Students will submit an outline and compose a three-page (research/evaluation) paper.
Instructions:
Make sure that your paper has:
•
A clear, concise, and defined thesis statement that occurs in the first portion of the paper.
•
Clear and logical transitions between the introduction, body, and conclusion.
•
Body paragraphs that include evidential support.
•
Evidential support (whether factual, logical, statistical, or anecdotal).
•
A conclusion that does not simply restate the thesis but readdresses it in light of the evidence provided.
Due Date:
Your three-page paper is due March 15. When typing your paper, please be sure to double-space and to use the standard 12-point font in either Times New Roman or Calibri. Follow MLA research guidelines. Be sure to also include a Works Cited.
Oxford Professor Says Genetically Altering Unborn Babies Personalities A Moral Obligation
By WakingTimes January 22, 2013
Aaron Jackson, Guest Writer
Waking Times
Genetically screening our offspring to make them better people is just “responsible parenting”, claims an eminent Oxford academic, The Telegraph reports.
Professor Julian Savulescu, editor-in-chief of the Journal of Medical Ethics, said that creating so-called designer babies could be considered a “moral obligation” as it makes them grow up into “ethically better children”, this based on a few genetic links to ‘personality disorders’.
He said that we should actively give parents the choice to screen out personality flaws in their children as it meant they were then less likely to “harm themselves and others”.
Studies show that the child’s upbringing, including parenthood and schooling methods are the root causes of many ‘personality flaws’. Other studies give strong evidence that nutrition, meditation and exercise greatly influence behavioural patterns and emotional well-being. This entire theory is also blind to the side effects of many medicines, vaccines, food additives and (some) GMO foods that have been proven to affect psychological behaviour, and this isn’t even touching on the possible beneficial use of marijuana and other substances for those with undesired personality traits.
“Surely trying to ensure that your children have the best, or a good enough, opportunity for a great life is responsible parenting?” wrote Prof Savulescu, the Uehiro Professor in practical ethics ...
The document is a resume for Ari Gilad Mandler that outlines his education, clinical and laboratory experience, honors, and extracurricular activities. It shows that he attends the University of Maryland where he majors in Neurobiology and Physiology with a 3.972 GPA. His clinical experiences include working as a medical scribe at Suburban Hospital and providing Spanish translation at Holy Cross Health Hospital. He has also conducted research investigating cell apoptosis inhibition in tuberculosis at UMD and prion disease propagation at Northwestern.
This document summarizes discussions from the 6th Genomic Medicine Colloquium hosted by the National Human Genome Research Institute. The colloquium brought together 50 international genomic medicine leaders from 25 countries to discuss opportunities for collaboration. Key areas of discussion included establishing standards for genomic data storage, implementing global pharmacogenomic screening programs, developing genomic medicine policy, and creating an international genomic medicine collaborative.
This curriculum vitae summarizes Michelle Renee Tourigny's work experience and education. She has over 20 years of experience in flow cytometry and 14 years working with mouse models. Her positions include graduate research assistant, flow cytometry facility manager, and postdoctoral fellow. She received a Ph.D. in Immunology from Cornell University and has skills in flow cytometry, cell culture, mouse work, and immunological techniques.
Robert Pesich_PAVA_Stanford Resume v. 8_22_16Robert Pesich
Robert Pesich has extensive experience managing laboratory operations and research projects. He has overseen the daily activities of 25 researchers at Stanford University and the Palo Alto VA, including managing budgets, equipment, and regulatory compliance. Pesich has specialized skills in tissue sample processing, gene expression analysis, and bioinformatics. He has authored several publications characterizing gene expression profiles in normal and diseased tissues. Currently, Pesich also serves as President of a poetry non-profit organization.
Advancing Innovation and Convergence in Cancer Research: US Federal Cancer Mo...Jerry Lee
Special Seminar at the 8th Taiwan Biosignatures Workshop to share overall work of NCI's Center for Strategic Scientific Initiatives since 2003 as well as CSSI's influence on select projects initiated by the 2016 WH Cancer Moonshot Task Force that include Applied Proteogenomics Organizational Learning and Outcomes (APOLLO) network, International Cancer Proteogenome Consortium, and the Blood Profiling Atlas in Cancer (BloodPAC) commons.
This document describes OrCanome, a comprehensive database for oral cancer research. OrCanome integrates genomic, transcriptomic, and proteomic data for over 900 genes associated with oral cancer. It provides detailed annotations for genes, transcripts, proteins, pathways, expression data, inhibitors, epitopes, and literature references. OrCanome aims to facilitate the identification of potential biomarkers and therapeutic targets for oral cancer by providing a centralized resource with integrated data from multiple omics studies.
1. Whole genome sequencing is becoming more affordable and widespread, allowing for large datasets and personalized medicine applications.
2. However, genomic data is extremely sensitive and can be used to identify individuals and their relatives, even when anonymized. Once a genome is leaked, it cannot be revoked.
3. Computer scientists are exploring techniques to protect genomic privacy, such as differential privacy and secure computation, but enabling privacy-preserving genomic research remains a challenge.
Lam C. Tsoi is a Research Assistant Professor at the University of Michigan in the Departments of Dermatology and Computational Medicine and Bioinformatics. He received his Ph.D. in Biomedical Science from the Medical University of South Carolina in 2010. His research focuses on using genomics data and computational approaches to provide biological insights into human cutaneous diseases such as psoriasis. He has published over 20 papers on identifying genetic risk loci and biological mechanisms for psoriasis and other autoimmune diseases.
Janae Caviness is seeking a full-time position in a pharmaceutical/biotech company where she can utilize her skills in cell culture, molecular biology techniques, and experience working in a regulated environment. She holds an MS in Molecular and Cellular Neuroscience from Delaware State University and a BS in Animal Science from Virginia State University. Her research experience includes investigating a compound's potential as a Parkinson's disease therapeutic through molecular experiments and behavioral analysis in mice models. Currently she works as a Cell Culture Scientist at Eurofins Lancaster Laboratories, where she performs upstream vaccine processing and development.
Gene testing examines an individual's DNA to detect genetic mutations and abnormalities. It can be performed using molecular genetic testing to detect specific DNA mutations or cytogenetic testing to examine changes in chromosomes. While gene testing provides benefits like helping to diagnose inherited diseases, it also raises issues regarding privacy, discrimination, and selective breeding. Further considerations include the high cost of testing and long wait times for results.
This resume summarizes the qualifications of Jane Yang, a scientist with extensive experience in cancer biology, transcriptional and epigenetic regulation, and cell differentiation. She has over 15 years of research experience, including positions at Genentech and Stanford University where she led projects discovering new mechanisms of action for small molecule inhibitors and identifying protein complexes involved in cell fate decisions. Her publications include high-impact articles in journals such as Cell Death and Differentiation and Genes & Development. She has strong skills in molecular and biochemical techniques and has received competitive NIH funding and honors for her work.
Similar to 2015 05-19 mechelinus-sukukokous_mp_tark (20)
This document summarizes the results of a genetic genealogy study of the Zitting surname. It finds that:
1) The Zitting males in the study belong to the R1a Y-DNA haplogroup, and more specifically the R1a1a1b1a2a subgroup, as predicted by an expert.
2) Americans with the Zitting surname also belong to the R1a haplogroup, with defining SNPs of M198 and M17.
3) The distribution of the rare R1a1a1b1a2a subgroup is examined, finding matches in other populations.
4) Autosomal DNA results for one individual are shown as an
The document discusses direct-to-consumer genetic testing services. It lists over 30 companies that offer such DNA tests covering ancestry, ethnicity, health, and other areas. The four largest companies - Family Tree DNA, 23andMe, Ancestry, and National Geographic - are highlighted. Business models for consumer genetic services are reviewed. Tools for self-analysis of DNA data like Promethease and SNPedia are presented. Research on the ethics of these direct-to-consumer tests is cited, and some ethical questions raised are ownership of genetic data, privacy, and informed consent.
Marja Pirttivaara gave a presentation on bridging social media and DNA at the Family Tree DNA 9th Genetic Genealogy Conference in Houston on November 10, 2013. She discussed how Finns have a strong presence in DNA due to Finland's unique population structure, migration history, and world-class genetic research. She also outlined how Finns actively use social media like Facebook, forums, blogs and Twitter for genetic genealogy networking, and provided tips on privacy, intellectual property and integrating social media platforms.
This presentation by Professor Alex Robson, Deputy Chair of Australia’s Productivity Commission, was made during the discussion “Competition and Regulation in Professions and Occupations” held at the 77th meeting of the OECD Working Party No. 2 on Competition and Regulation on 10 June 2024. More papers and presentations on the topic can be found at oe.cd/crps.
This presentation was uploaded with the author’s consent.
This presentation by Thibault Schrepel, Associate Professor of Law at Vrije Universiteit Amsterdam University, was made during the discussion “Artificial Intelligence, Data and Competition” held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/aicomp.
This presentation was uploaded with the author’s consent.
This presentation by Katharine Kemp, Associate Professor at the Faculty of Law & Justice at UNSW Sydney, was made during the discussion “The Intersection between Competition and Data Privacy” held at the 143rd meeting of the OECD Competition Committee on 13 June 2024. More papers and presentations on the topic can be found at oe.cd/ibcdp.
This presentation was uploaded with the author’s consent.
This presentation by OECD, OECD Secretariat, was made during the discussion “Pro-competitive Industrial Policy” held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/pcip.
This presentation was uploaded with the author’s consent.
This presentation by Nathaniel Lane, Associate Professor in Economics at Oxford University, was made during the discussion “Pro-competitive Industrial Policy” held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/pcip.
This presentation was uploaded with the author’s consent.
This presentation by OECD, OECD Secretariat, was made during the discussion “The Intersection between Competition and Data Privacy” held at the 143rd meeting of the OECD Competition Committee on 13 June 2024. More papers and presentations on the topic can be found at oe.cd/ibcdp.
This presentation was uploaded with the author’s consent.
This presentation by OECD, OECD Secretariat, was made during the discussion “Artificial Intelligence, Data and Competition” held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/aicomp.
This presentation was uploaded with the author’s consent.
This presentation by Professor Giuseppe Colangelo, Jean Monnet Professor of European Innovation Policy, was made during the discussion “The Intersection between Competition and Data Privacy” held at the 143rd meeting of the OECD Competition Committee on 13 June 2024. More papers and presentations on the topic can be found at oe.cd/ibcdp.
This presentation was uploaded with the author’s consent.
Carrer goals.pptx and their importance in real lifeartemacademy2
Career goals serve as a roadmap for individuals, guiding them toward achieving long-term professional aspirations and personal fulfillment. Establishing clear career goals enables professionals to focus their efforts on developing specific skills, gaining relevant experience, and making strategic decisions that align with their desired career trajectory. By setting both short-term and long-term objectives, individuals can systematically track their progress, make necessary adjustments, and stay motivated. Short-term goals often include acquiring new qualifications, mastering particular competencies, or securing a specific role, while long-term goals might encompass reaching executive positions, becoming industry experts, or launching entrepreneurial ventures.
Moreover, having well-defined career goals fosters a sense of purpose and direction, enhancing job satisfaction and overall productivity. It encourages continuous learning and adaptation, as professionals remain attuned to industry trends and evolving job market demands. Career goals also facilitate better time management and resource allocation, as individuals prioritize tasks and opportunities that advance their professional growth. In addition, articulating career goals can aid in networking and mentorship, as it allows individuals to communicate their aspirations clearly to potential mentors, colleagues, and employers, thereby opening doors to valuable guidance and support. Ultimately, career goals are integral to personal and professional development, driving individuals toward sustained success and fulfillment in their chosen fields.
The importance of sustainable and efficient computational practices in artificial intelligence (AI) and deep learning has become increasingly critical. This webinar focuses on the intersection of sustainability and AI, highlighting the significance of energy-efficient deep learning, innovative randomization techniques in neural networks, the potential of reservoir computing, and the cutting-edge realm of neuromorphic computing. This webinar aims to connect theoretical knowledge with practical applications and provide insights into how these innovative approaches can lead to more robust, efficient, and environmentally conscious AI systems.
Webinar Speaker: Prof. Claudio Gallicchio, Assistant Professor, University of Pisa
Claudio Gallicchio is an Assistant Professor at the Department of Computer Science of the University of Pisa, Italy. His research involves merging concepts from Deep Learning, Dynamical Systems, and Randomized Neural Systems, and he has co-authored over 100 scientific publications on the subject. He is the founder of the IEEE CIS Task Force on Reservoir Computing, and the co-founder and chair of the IEEE Task Force on Randomization-based Neural Networks and Learning Systems. He is an associate editor of IEEE Transactions on Neural Networks and Learning Systems (TNNLS).
Suzanne Lagerweij - Influence Without Power - Why Empathy is Your Best Friend...Suzanne Lagerweij
This is a workshop about communication and collaboration. We will experience how we can analyze the reasons for resistance to change (exercise 1) and practice how to improve our conversation style and be more in control and effective in the way we communicate (exercise 2).
This session will use Dave Gray’s Empathy Mapping, Argyris’ Ladder of Inference and The Four Rs from Agile Conversations (Squirrel and Fredrick).
Abstract:
Let’s talk about powerful conversations! We all know how to lead a constructive conversation, right? Then why is it so difficult to have those conversations with people at work, especially those in powerful positions that show resistance to change?
Learning to control and direct conversations takes understanding and practice.
We can combine our innate empathy with our analytical skills to gain a deeper understanding of complex situations at work. Join this session to learn how to prepare for difficult conversations and how to improve our agile conversations in order to be more influential without power. We will use Dave Gray’s Empathy Mapping, Argyris’ Ladder of Inference and The Four Rs from Agile Conversations (Squirrel and Fredrick).
In the session you will experience how preparing and reflecting on your conversation can help you be more influential at work. You will learn how to communicate more effectively with the people needed to achieve positive change. You will leave with a self-revised version of a difficult conversation and a practical model to use when you get back to work.
Come learn more on how to become a real influencer!
XP 2024 presentation: A New Look to Leadershipsamililja
Presentation slides from XP2024 conference, Bolzano IT. The slides describe a new view to leadership and combines it with anthro-complexity (aka cynefin).
This presentation by Tim Capel, Director of the UK Information Commissioner’s Office Legal Service, was made during the discussion “The Intersection between Competition and Data Privacy” held at the 143rd meeting of the OECD Competition Committee on 13 June 2024. More papers and presentations on the topic can be found at oe.cd/ibcdp.
This presentation was uploaded with the author’s consent.
3. Ihmisen perimä
Ihmisellä on
• yksi perimä eli genomi,
• soluja noin 1014 (*),
• 23 kromosomiparia,
• kromosomeissa geenejä noin
23 000,
• perimässä emäspareja noin
kolme miljardia,
• SNPt eli snippi on yhden
emäksen monimuotoisuus.
19.5.2015
• http://www.biomag.hus.fi/braincourse/L2.htm
l
Marja Pirttivaara
4. “Neljä suurta” tarjoavat testejä
• Family Tree DNA (FTDNA) http://www.familytreedna.com
• 23andMe http://www.23andme.com
• Ancestry http://www.ancestry.com
• National Geographic https://genographic.nationalgeographic.com/
• Lisäksi muita pienempiä:
http://www.isogg.org/wiki/List_of_DNA_testing_companies
• Kuluttajagenomiikan markkinoiden uskotaan kasvavan edelleen
nopeasti, vuoden 2015 aikana saavutetaan todennäköisesti kolmen
miljoonan testatun raja. (Spencer Wells, director, National Geographic
Genographic Project).
• Esim. Family Tree DNA perustestit: Y-DNA (isälinja), mtDNA (äitilinja) ja
Family Finder (autosomaali DNA ja X kromosomi, yht. n. 700 000
snippiä; ”etäserkkutesti”)
19.5.2015 Marja Pirttivaara
6. Suomi DNA projekti
19.5.2015 Marja Pirttivaara 6
Lkm
Yht. jäseniä 5186
Y-DNA 12 3504
Y-DNA 67 2563
Y-DNA 111 593
BIG Y 202
Geno 2.0 Tr. 133
mtDNA 2649
mtDNA Full 1610
Family Finder 1935
10. Gene by Gene & MD Anderson Cancer Center 1/2
Lehdistötiedote (4/2013): Gene By Gene Signs Agreement with MD Anderson Cancer Center
Will provide clinical phase instruction, training and supervision for students as part of agreement
HOUSTON — Apr. 23, 2013 – Gene By Gene, Ltd., the Houston-based genomics and genetics testing company, announced that it
has signed an agreement with the University of Texas MD Anderson Cancer Center to become one of its affiliated clinical
laboratories.
Under the agreement, scientists at Gene By Gene’s Genomic Research Center will provide the clinical phase instruction, training
and supervision required for students in the Molecular Genetic Technology Program, one of eight undergraduate programs
offered through MD Anderson’s School of Health Professions.
“We’re delighted to partner with Gene By Gene, with its long and pioneering history in the field of genomics,” said Program
Director, Peter Hu, Ph.D., with the School of Health Professions. “Gene By Gene’s sequencing, next-generation sequencing and
microarray laboratory will provide the top level of experience and training that we want all our molecular students to attain.
”Gene By Gene’s Genomic Research Center is a CLIA registered lab which has processed more than 5 million discrete DNA tests
from more than 700,000 individuals and organizations globally. It is now one of only 36 laboratories in the United States,
including the Yale University School of Medicine and the Baylor College of Medicine, to achieve this prestigious affiliation.
“We’re very proud to be able to share our laboratory and expertise with MD Anderson’s School of Health Professions,” said Gene
By Gene President Bennett Greenspan. “It’s an honor to be among the select few companies and institutions that are invited to
affiliate with this prestigious institution. In addition, this is a wonderful opportunity for Gene By Gene to continue investing in the
next generation of leaders in genomic and genetic science, and we’re thrilled to welcome the first students to our Genomics
Research Center this May.”
http://dna-explained.com/2013/04/23/gene-by-gene-signs-agreement-with-md-anderson-cancer-center/
19.5.2015 Marja Pirttivaara
11. Gene by Genen yhteistyökumpani
MD Anderson Cancer Center
19.5.2015 Marja Pirttivaara
12. Tieteellisiä julkaisuja liittyen FTDNAn testaamiin näytteisiin 1/8
19.5.2015 Marja Pirttivaara
* Arunkumar et al: Population differentiation of southern Indian male lineages correlates with
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13. Tieteellisiä julkaisuja liittyen FTDNAn testaamiin näytteisiin 2/8
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* Birds: Towards Improvements in the Estimation of the Coalescent: Implications for the
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* Boattini et al: Uniparental markers in Italy reveal a sex-biased genetic structure and
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* Brandt et al: Ancient DNA reveals key stages in the formation of central European
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14. Tieteellisiä julkaisuja liittyen FTDNAn analysoimiin näytteisiin 3/8
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* Cai et al: Human migration through bottlenecks from Southeast Asia into East Asia during Last
Glacial Maximum revealed by Y chromosomes. PLoS One. 2011;6(8):e24282. doi:
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* Cariaso & Lennon: SNPedia: a wiki supporting personal genome annotation, interpretation and
analysis Nucleic Acids Res. 2012 January; 40(Database issue): D1308–D1312. Published online 2011
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* Clarke et al: From cheek swabs to consensus sequences: an A to Z protocol for high-throughput
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* Der Sarkissian et al: Mitochondrial genome sequencing in Mesolithic North East Europe Unearths
a new sub-clade within the broadly distributed human haplogroup C1. PLoS One. 2014 Feb
4;9(2):e87612. doi: 10.1371/journal.pone.0087612. eCollection 2014.
* Der Sarkissian et al: Ancient DNA reveals prehistoric gene-flow from Siberia in the complex
human population history of North East Europe. PLoS Genet. 2013;9(2):e1003296. doi:
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* Derenko et al: Complete Mitochondrial DNA Analysis of Eastern Eurasian Haplogroups Rarely
Found in Populations of Northern Asia and Eastern Europe PLoS One. 2012; 7(2): e32179. Published
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* Derenko et al: Origin and Post-Glacial Dispersal of Mitochondrial DNA Haplogroups C and D in
Northern Asia PLoS One. 2010; 5(12): e15214. Published online 2010 December 21.
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15. Tieteellisiä julkaisuja liittyen FTDNAn analysoimiin näytteisiin 4/7
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* Dulik et al: Y-chromosome analysis reveals genetic divergence and new founding native lineages in
Athapaskan- and Eskimoan-speaking populations. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8471-6.
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2009 Aug 16.
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Lebanon. Eur J Hum Genet. 2011 Mar;19(3):334-40. doi: 10.1038/ejhg.2010.177. Epub 2010 Dec 1.
16. Tieteellisiä julkaisuja liittyen FTDNAn analysoimiin näytteisiin 5/7
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* Javed et al: Recombination networks as genetic markers in a human variation study of the Old World.
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* Kang et al: Y-chromosome O3 haplogroup diversity in Sino-Tibetan populationsreveals two migration
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* Martinez-Cruz et al: Y-chromosome analysis in individuals bearing the Basarab name of the first
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23. M269
P311P312
Z195
L21
U152
U1
06
L48
U106
P311 L21
M269 L11
P312 Z195
U152
Post-Neolithic Centers of
Renewed Expansion
SRY
2627
M222
Prof. Michael Hammer, Origins of R-M269 Diversity in Europe, Houston 11.2013
Haploryhmän R-M269 leviäminen Euroopassa
19.5.2015
24. Bourbonin suvun DNA 1/4
Larmuseaus et al: Genetic genealogy reveals true Y haplogroup of House of Bourbon contradicting recent identification
of the presumed remains of two French Kings, Eur J of Human Genetics, s (2014) 22, 681–68
Copyrights for the use in this presentation from RightsLink
Henrik IV:n kuva: Wikipedia
19.5.2015 Marja Pirttivaara
25. Bourbonin suvun DNA 2/4
Larmuseaus et al: Genetic genealogy reveals true Y haplogroup of House of Bourbon contradicting recent
identification of the presumed remains of two French Kings, Eur J of Human Genetics, s (2014) 22, 681–68
Copyrights for the use in this presentation from RightsLink
19.5.2015 Marja Pirttivaara
26. Bourbonin suvun DNA 3/4
Larmuseaus et al: Genetic genealogy reveals true Y haplogroup of House of Bourbon contradicting
recent identification of the presumed remains of two French Kings, Eur J of Human Genetics, s (2014)
22, 681–68. Copyrights for the use in this presentation from RightsLink
19.5.2015 Marja Pirttivaara
27. Bourbonin suvun DNA 4/4
• Ranskalaisen Bourbon-suvun Y-DNA saatiin konstruoitua (tn
R1b1b2a1a1b* R-Z381*).
• Oletetut Henrik IV:n pään ja Ludwig XVI:n verinäytteen Y-DNA eivät
täsmänneet konstruoidun Bourbon-Y-DNAn kanssa.
• Pään mtDNA (U5b*) ei täsmää elävien henkilöiden näytteistä
johdettuun kuninkaan äidin mtDNAhan (H).
• Joko näytteet olivat kontaminoituneet tai henkilöllisyydet eivät
täsmää.
• Osoittaa vertailun tärkeyden. Yksi näyte ei riitä.
19.5.2015 Marja Pirttivaara
Larmuseaus et al: Genetic genealogy reveals true Y haplogroup of House of Bourbon contradicting recent
identification of the presumed remains of two French Kings, Eur J of Human Genetics, s (2014) 22, 681–68
Copyrights for the use in this presentation from RightsLink
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992573/pdf/ejhg2013211a.pdf
Dienekes blog: House of Bourbon belonged to Y-haplogroup R1b1b2a1a1b* (R-Z381*)
http://dienekes.blogspot.fi/2013/10/house-of-bourbon-belonged-to-y.html
28. Etiikka ja yksityisyys
• Suomen Sukututkimusseuran
käytännesäännöt
• Geneettisen sukututkimuksen
kansainväliset standrdit 2015
• Ihmisellä on oikeus tietää ja olla
tietämättä
• DNAn omistusoikeus
Marja Pirttivaara19.5.2015
29. Testien tilaus & lisätietoa
• Family Tree DNA Suomi DNA projekti
– https://www.familytreedna.com/groups/finland/about/background
– https://www.familytreedna.com/group-
join.aspx?&group=Finland&vGroup=Finland
• International Society of Genetic Genealogy ISOGG
http://www.isogg.org
• SNPedia ja Promethease http://www.snpedia.com
• Suomen Sukututkimusseura luentoja, mentorointipalvelu jne
http://www.genealogia.fi
Marja Pirttivaara19.5.2015