This document provides a history of food safety regulation in the United States from the early 20th century to the present. It describes key events that shaped policy, including Upton Sinclair's The Jungle exposing unsanitary conditions in the meat industry, leading to the 1906 Pure Food and Drug Act. Outbreaks of foodborne illness continued to impact policy over the decades. The Food Safety Modernization Act of 2010 was a major milestone, though some argued it did not go far enough and was still facing challenges to full implementation.