Isabella Meikle was born in 1837 in Scotland and immigrated to Utah in 1856 with her mother and siblings as part of the second handcart company. She married William Blackhurst in 1857 and had four children, but he passed away in 1864. She then married Theodore Curtis in 1868 and had two more daughters, but Isabella herself passed away in 1873 from dropsy at the young age of 35.