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Raphael Center for Integrative Orthodontics Dr. Barry Raphael. Spreecast: Better Faces Less Braces.
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Jennlevydiseaseppt
Osteogenesis imperfecta is a genetic disorder caused by a defect in the collagen gene that results in brittle bones that break easily from minor stress or trauma. There are four main types of OI that vary in severity from very mild to lethal in infancy. While there is no cure for OI, treatments focus on increasing bone strength through bisphosphonates and low-impact exercise, as well as surgery to repair broken bones. People with OI must manage their condition for life through precautions to avoid further fractures.
Spreecast post show
This document provides information about an episode of "The Airway and Facial Development Collaborative" podcast that featured Dr. Keith Thornton discussing severe obstructive sleep apnea and the neuromuscular patient. It also lists upcoming dental courses on restorative dentistry, dental sleep medicine, and airway, breathing and sleep. Contact information is provided for subscribing and providing feedback. The document ends with a quote from Martin Luther King Jr. about continuing to move forward.
Spreecast pre show Turzo
Dr. Tasha Turzo presented on the etiology of facial dysfunction. The episode, produced by Drs. Mark Cruz and Barry Raphael, focused on the origins of facial issues. Dr. Turzo has 18 years experience as an osteopathic physician and classical homeopath specializing in treating facial dysfunctions, TMD, malocclusions, and head injuries. She is a founding faculty member at the ALF Educational Institute and received degrees from the College of Osteopathic Medicine of the Pacific and certifications in homeopathy, osteopathic cranial techniques, and Prolotherapy.
1 rcio spreecast intro
Raphael Center for Integrative Orthodontics Dr. Barry Raphael. Spreecast: Better Faces Less Braces.
Turzo 2 etiology spreecast
The document discusses the philosophy of osteopathy, which is that the body has an inherent ability to heal itself through a self-regulatory mechanism. It then covers various factors that can impact facial development in children, including breathing, swallowing, chewing, brain growth, and vision. Traumas and dysfunctions like birth complications, breathing issues, non-functional orthodontic treatments, and myofunctional disorders are discussed as potential etiologies for mandibular and facial development issues.
AMR case presentation format
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help alleviate symptoms of mental illness and boost overall mental well-being.
3 rcio spreecast malocclusion
Raphael Center for Integrative Orthodontics Dr. Barry Raphael. Spreecast: Better Faces Less Braces.
Airway ortho 1 the three airway problems
A series of lectures by Dr. Barry Raphael on Airway-focused orthodontics from 2013.
Chapter 1: An editorial look at the forces that are changing orthodontics today and how they will influence what orthodontics is to become in the 21st century.
Recommended
Jennlevydiseaseppt
Osteogenesis imperfecta is a genetic disorder caused by a defect in the collagen gene that results in brittle bones that break easily from minor stress or trauma. There are four main types of OI that vary in severity from very mild to lethal in infancy. While there is no cure for OI, treatments focus on increasing bone strength through bisphosphonates and low-impact exercise, as well as surgery to repair broken bones. People with OI must manage their condition for life through precautions to avoid further fractures.
Spreecast post show
This document provides information about an episode of "The Airway and Facial Development Collaborative" podcast that featured Dr. Keith Thornton discussing severe obstructive sleep apnea and the neuromuscular patient. It also lists upcoming dental courses on restorative dentistry, dental sleep medicine, and airway, breathing and sleep. Contact information is provided for subscribing and providing feedback. The document ends with a quote from Martin Luther King Jr. about continuing to move forward.
Spreecast pre show Turzo
Dr. Tasha Turzo presented on the etiology of facial dysfunction. The episode, produced by Drs. Mark Cruz and Barry Raphael, focused on the origins of facial issues. Dr. Turzo has 18 years experience as an osteopathic physician and classical homeopath specializing in treating facial dysfunctions, TMD, malocclusions, and head injuries. She is a founding faculty member at the ALF Educational Institute and received degrees from the College of Osteopathic Medicine of the Pacific and certifications in homeopathy, osteopathic cranial techniques, and Prolotherapy.
1 rcio spreecast intro
Raphael Center for Integrative Orthodontics Dr. Barry Raphael. Spreecast: Better Faces Less Braces.
Turzo 2 etiology spreecast
The document discusses the philosophy of osteopathy, which is that the body has an inherent ability to heal itself through a self-regulatory mechanism. It then covers various factors that can impact facial development in children, including breathing, swallowing, chewing, brain growth, and vision. Traumas and dysfunctions like birth complications, breathing issues, non-functional orthodontic treatments, and myofunctional disorders are discussed as potential etiologies for mandibular and facial development issues.
AMR case presentation format
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help alleviate symptoms of mental illness and boost overall mental well-being.
3 rcio spreecast malocclusion
Raphael Center for Integrative Orthodontics Dr. Barry Raphael. Spreecast: Better Faces Less Braces.
Airway ortho 1 the three airway problems
A series of lectures by Dr. Barry Raphael on Airway-focused orthodontics from 2013.
Chapter 1: An editorial look at the forces that are changing orthodontics today and how they will influence what orthodontics is to become in the 21st century.
genetics proj
Lowe Syndrome is an extremely rare genetic disorder that only affects boys. It causes cataracts, glaucoma, underdeveloped motor and mental skills, rickets, fractures, kidney problems, and reduced life expectancy of 30-40 years. The document profiles three boys with Lowe Syndrome - Adam, who suffered a stroke at age 16 leaving him unable to walk or speak; Leland, whose death at age 22 motivated his mother to start the Lowe Syndrome Association; and Jonathon, a 16 year old in Scotland who requires around-the-clock care for his medical needs and disabilities. Families of those with Lowe Syndrome devote significant resources to medical care, but the boys generally behave like typical boys despite their condition.
Etiology of malocclusion general factors
This document discusses the etiology, or causes, of malocclusion. It begins with an introduction and overview of common systems of classification for etiologic factors. It then discusses several of these classification systems in more detail, including White and Gardiner's, Salzmann's, Moyer's, Graber's, and Proffit's classifications. The document outlines the primary sites where etiologic factors act, including the neuromuscular system, bones of the facial skeleton, teeth, and soft tissues. It then discusses hereditary/genetic factors in detail, including twin and familial studies. Other sections cover congenital malformations, environmental influences, and specific conditions like cleft lip and palate.
Airway ortho 3 darwinian orthodontics
A series of lectures by Dr. Barry Raphael on Airway-focused orthodontics from 2013
Chapter 3: How Evolutionary Medicine and anthropology informs Orthodontic diagnosis and treatment planning.
Disorders of the teeth & bone
This document discusses various disorders of teeth and bone. It describes developmental disorders that can cause variations in tooth number, size, shape, eruption and structure. Tooth structure disorders include enamel hypoplasia, dentinogenesis imperfecta and amelogenesis imperfecta. Bone disorders discussed include cleidocranial dysplasia, fibrous dysplasia, gigantism/acromegaly, hyperparathyroidism, hypoparathyroidism, osteoporosis, rickets and Paget's disease. Causes, clinical features, diagnoses and treatments are provided for each condition.
Everything you Need to Know About Progeria
A power point I made for my Honor's Biology class while learning about genetics.
I hope you find it useful!
6-Birth-Defects.ppt
Birth defects are abnormalities present at birth that can cause disabilities or death. They range from minor to serious and affect about 150,000 babies born in the US each year. Common birth defects include spina bifida, caused by inadequate folic acid during early pregnancy and clubfoot. Spina bifida occurs when the bones of the spinal column do not fully close, leaving an opening. Early prenatal surgery may help repair some birth defects. Fetal alcohol syndrome, caused by drinking during pregnancy, can result in physical deformities and neurological issues. Cerebral palsy is caused by brain injury before or during birth and results in difficulties with movement and posture. Down syndrome, caused by an extra 21st chromosome, leads to intellectual
Skeptic-EvolPerspChronDis(color)
1) Modern chronic diseases like diabetes, heart disease, and Alzheimer's are increasingly prevalent, costly to treat, and largely preventable through lifestyle changes rather than just medical treatment of symptoms.
2) These "diseases of civilization" have emerged with the agricultural and industrial revolutions and are mismatched with our evolutionary biology due to poor diets and lack of physical activity.
3) While medicine has focused on curing infectious diseases, it has been less effective at preventing chronic diseases and their rising rates through the generations by not emphasizing lifestyle and environmental factors.
Heirlooms, Hope Chests and Genes...What did you inherit?
This document discusses how family history can provide insight into health risks and discusses strategies for prevention. It addresses how to gather family history information, common conditions that may run in families like cancer, heart disease, diabetes, and Alzheimer's, and the increased risks associated with having an affected relative. The document emphasizes that knowing family history can help guide screening and encourage lifestyle changes to prevent conditions from repeating in the family history. It provides disease-specific risk statistics and recommendations for different screening and prevention approaches based on one's family history.
Dwarfism
There are over 300 causes of dwarfism, with the most common being a spontaneous mutation of the FGFR3 gene. The two main types of skeletal dysplasia that cause dwarfism are short trunk with average limbs, and average trunk with shorter limbs and larger head. People with dwarfism can lead normal, healthy lives through treatments like surgery, nutrition plans, physical therapy and hormone injections depending on the type of dwarfism. The likelihood of having a child with dwarfism depends on factors like the parents' height and whether one or both parents carry a dwarfism gene.
Osteogenesis imperfecta
Osteogenesis imperfecta (OI) is caused by mutations in genes that produce collagen, the main structural protein in bones and other tissues. There are several types of OI ranging from mild to lethal. Type I is the most common and mildest form. Type II is the most severe and often fatal form. There is no cure for OI but treatments can help manage symptoms and strengthen bones to prevent fractures and deformities. Research is ongoing to develop new treatments but a cure is not expected soon.
Geneticmutations 131005025415-phpapp01
This document discusses various genetic mutations and the diseases they cause. It begins by mentioning animal mutations and disorders like holoprosencephaly. Then it discusses several human genetic diseases including Down syndrome, Edwards syndrome, Patau syndrome, Klinefelter syndrome, and Turner syndrome. It provides brief descriptions and examples of trisomy, monosomy, Kleinfelter's syndrome, Huntington's disease, diabetes, color blindness, albinism, clubfoot, osteogenesis imperfecta, cleft lip and palate, progeria, and an X-linked trait causing hairy ears. References are provided at the end for additional reading.
Swastha - Nutraceuticals.
This document summarizes information about a company called Synix HK Limited that produces herbal supplements under the brand Swastha. It discusses the company's founding and commitment to customer health. The company listens to customers and ensures product safety through rigorous testing of raw materials. The goal is to reduce lifestyle diseases through herbal supplements. The document then provides information on various supplements for wellness, weight loss, and cardiovascular/diabetes issues. It discusses the active ingredients in wheatgrass and their health benefits. Finally, contact information for the company is listed.
Autism enigma
This document provides biographical information about Dr. Cem Kinaci and discusses his background and experience in nuclear medicine. It also lists his professional affiliations with various medical organizations. The bulk of the document then covers topics related to autism spectrum disorder (ASD), including recognized tendencies, possible causes, predisposing factors, and biochemical effects associated with ASD.
Osteoporosis edited-100201092008-phpapp02
This document discusses osteoporosis, including its causes, risk factors, symptoms, diagnosis, and treatment. It describes osteoporosis as a systemic disease characterized by decreased bone strength and increased fracture risk. Key points made include:
- Osteoporosis has no symptoms until a fracture occurs and is known as the "silent epidemic".
- Risk factors include age, gender, family history, smoking, lack of exercise, and low calcium/vitamin D intake.
- Screening is recommended for women over 65 and younger women with risk factors using dual-energy x-ray absorptiometry (DEXA) scans.
- Treatment focuses on lifestyle changes like exercise, fall prevention, and calcium
FIBRO OSSEOUS LESIONS.pptx
1) Fibro-osseous lesions are a group of pathological changes where normal bone is replaced by fibrous tissue with or without calcification. The WHO classifies several types including ossifying fibroma, fibrous dysplasia, and cherubism.
2) Fibrous dysplasia is caused by a mutation in the GNAS1 gene and can be monostotic (one bone) or polyostotic (multiple bones). It is characterized by replacement of bone with fibro-osseous tissue.
3) Radiologically, fibrous dysplasia lesions appear radiolucent, radiopaque, or mixed depending on the site. In the jaws, lesions are often located in
Designer babies
The document discusses various genetic concepts including dominant and recessive alleles, traits being expressed in offspring from the combination of parental alleles, and different types of genetic disorders. It then discusses the concept of designer babies, including how genetic screening can reduce risks of diseases and disabilities in offspring. While designer babies allow for choosing traits, some argue it could lead to eugenics. The document concludes that designer babies may help prevent miscarriages and diseases.
Designer babies
The document discusses various genetic concepts including dominant and recessive alleles, traits being expressed in offspring from the combination of parental alleles, and different types of genetic disorders. It then discusses the concept of designer babies, including how genetic screening can reduce risks of diseases and disabilities in offspring. While designer babies allow for choosing traits, some argue it could lead to eugenics. The document concludes that designer babies may help prevent miscarriages and diseases.
Patterns of Inheritance
This document discusses patterns of inheritance and genetics terminology. It defines key terms like allele, genotype, phenotype, dominant and recessive traits. It explains Mendel's laws of segregation and independent assortment. It provides examples of monohybrid and dihybrid crosses using Punnett squares. It also discusses exceptions to Mendel's laws like incomplete dominance and codominance. Finally, it covers sex-linked inheritance and examples of X-linked disorders.
Saliva
Saliva is produced in the salivary glands and is mostly water. It contains electrolytes, mucus, enzymes and antibacterial compounds. Saliva keeps the mouth moist, aids in chewing, tasting and swallowing, and fights germs to prevent bad breath and protect teeth from decay. The amount of saliva produced varies from 2-4 pints per day depending on factors like how much one chews. Too little or too much saliva can be caused by various diseases, medications, or conditions that impact the salivary glands or nervous system. Saliva testing is also used for early drug detection due to its correlation with impairment.
"The Science of Aging" by Martin Borch Jensen
Slides from the inaugural Impact.tech seminar about the science of aging, healthspan and longevity. The presentation addresses questions such as: What is aging? Is aging treatable? What are the major biological processes that make up aging? What are the major breakthroughs in anti-aging science? How you can get involved in anti-aging as an entrepreneur or investor?
Impact.tech Launch Seminars are meant to give entrepreneurs and investors a launch into a topic where they can apply their skills to make a major positive impact for humanity and the world.
Ep 52 Spreecast pre show
This document provides information about multiple episodes of "The Airway and Facial Development Collaborative", a podcast produced by Drs. Mark A. Cruz and Barry Raphael. It lists the episode numbers, dates, guest speakers, and brief episode titles for over 50 past episodes dating back to January 2014. The episodes discuss various topics related to airway dentistry, sleep, breathing, orthodontics, posture, and interdisciplinary collaboration between dental and medical professionals.
Spreecast 51 amr algo
This document discusses respiratory and breathing physiology. It provides an overview of evaluating upper airway function, including tests like HRPO, pharyngometry, rhinometry, and CBCT. It also discusses treating conditions like UARS, LPR, and OSA with therapies like CPAP, OAT, MMA, and MFT. The document lists potential medical sequelae that can result from untreated airway and breathing issues, such as bruxism, anxiety, depression, fatigue, nocturia, hypertension, cognitive impairment, reflux, cough, asthma, mood swings, infertility, and more.
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Similar to 2 rcio spreecast big picture
genetics proj
Lowe Syndrome is an extremely rare genetic disorder that only affects boys. It causes cataracts, glaucoma, underdeveloped motor and mental skills, rickets, fractures, kidney problems, and reduced life expectancy of 30-40 years. The document profiles three boys with Lowe Syndrome - Adam, who suffered a stroke at age 16 leaving him unable to walk or speak; Leland, whose death at age 22 motivated his mother to start the Lowe Syndrome Association; and Jonathon, a 16 year old in Scotland who requires around-the-clock care for his medical needs and disabilities. Families of those with Lowe Syndrome devote significant resources to medical care, but the boys generally behave like typical boys despite their condition.
Etiology of malocclusion general factors
This document discusses the etiology, or causes, of malocclusion. It begins with an introduction and overview of common systems of classification for etiologic factors. It then discusses several of these classification systems in more detail, including White and Gardiner's, Salzmann's, Moyer's, Graber's, and Proffit's classifications. The document outlines the primary sites where etiologic factors act, including the neuromuscular system, bones of the facial skeleton, teeth, and soft tissues. It then discusses hereditary/genetic factors in detail, including twin and familial studies. Other sections cover congenital malformations, environmental influences, and specific conditions like cleft lip and palate.
Airway ortho 3 darwinian orthodontics
A series of lectures by Dr. Barry Raphael on Airway-focused orthodontics from 2013
Chapter 3: How Evolutionary Medicine and anthropology informs Orthodontic diagnosis and treatment planning.
Disorders of the teeth & bone
This document discusses various disorders of teeth and bone. It describes developmental disorders that can cause variations in tooth number, size, shape, eruption and structure. Tooth structure disorders include enamel hypoplasia, dentinogenesis imperfecta and amelogenesis imperfecta. Bone disorders discussed include cleidocranial dysplasia, fibrous dysplasia, gigantism/acromegaly, hyperparathyroidism, hypoparathyroidism, osteoporosis, rickets and Paget's disease. Causes, clinical features, diagnoses and treatments are provided for each condition.
Everything you Need to Know About Progeria
A power point I made for my Honor's Biology class while learning about genetics.
I hope you find it useful!
6-Birth-Defects.ppt
Birth defects are abnormalities present at birth that can cause disabilities or death. They range from minor to serious and affect about 150,000 babies born in the US each year. Common birth defects include spina bifida, caused by inadequate folic acid during early pregnancy and clubfoot. Spina bifida occurs when the bones of the spinal column do not fully close, leaving an opening. Early prenatal surgery may help repair some birth defects. Fetal alcohol syndrome, caused by drinking during pregnancy, can result in physical deformities and neurological issues. Cerebral palsy is caused by brain injury before or during birth and results in difficulties with movement and posture. Down syndrome, caused by an extra 21st chromosome, leads to intellectual
Skeptic-EvolPerspChronDis(color)
1) Modern chronic diseases like diabetes, heart disease, and Alzheimer's are increasingly prevalent, costly to treat, and largely preventable through lifestyle changes rather than just medical treatment of symptoms.
2) These "diseases of civilization" have emerged with the agricultural and industrial revolutions and are mismatched with our evolutionary biology due to poor diets and lack of physical activity.
3) While medicine has focused on curing infectious diseases, it has been less effective at preventing chronic diseases and their rising rates through the generations by not emphasizing lifestyle and environmental factors.
Heirlooms, Hope Chests and Genes...What did you inherit?
This document discusses how family history can provide insight into health risks and discusses strategies for prevention. It addresses how to gather family history information, common conditions that may run in families like cancer, heart disease, diabetes, and Alzheimer's, and the increased risks associated with having an affected relative. The document emphasizes that knowing family history can help guide screening and encourage lifestyle changes to prevent conditions from repeating in the family history. It provides disease-specific risk statistics and recommendations for different screening and prevention approaches based on one's family history.
Dwarfism
There are over 300 causes of dwarfism, with the most common being a spontaneous mutation of the FGFR3 gene. The two main types of skeletal dysplasia that cause dwarfism are short trunk with average limbs, and average trunk with shorter limbs and larger head. People with dwarfism can lead normal, healthy lives through treatments like surgery, nutrition plans, physical therapy and hormone injections depending on the type of dwarfism. The likelihood of having a child with dwarfism depends on factors like the parents' height and whether one or both parents carry a dwarfism gene.
Osteogenesis imperfecta
Osteogenesis imperfecta (OI) is caused by mutations in genes that produce collagen, the main structural protein in bones and other tissues. There are several types of OI ranging from mild to lethal. Type I is the most common and mildest form. Type II is the most severe and often fatal form. There is no cure for OI but treatments can help manage symptoms and strengthen bones to prevent fractures and deformities. Research is ongoing to develop new treatments but a cure is not expected soon.
Geneticmutations 131005025415-phpapp01
This document discusses various genetic mutations and the diseases they cause. It begins by mentioning animal mutations and disorders like holoprosencephaly. Then it discusses several human genetic diseases including Down syndrome, Edwards syndrome, Patau syndrome, Klinefelter syndrome, and Turner syndrome. It provides brief descriptions and examples of trisomy, monosomy, Kleinfelter's syndrome, Huntington's disease, diabetes, color blindness, albinism, clubfoot, osteogenesis imperfecta, cleft lip and palate, progeria, and an X-linked trait causing hairy ears. References are provided at the end for additional reading.
Swastha - Nutraceuticals.
This document summarizes information about a company called Synix HK Limited that produces herbal supplements under the brand Swastha. It discusses the company's founding and commitment to customer health. The company listens to customers and ensures product safety through rigorous testing of raw materials. The goal is to reduce lifestyle diseases through herbal supplements. The document then provides information on various supplements for wellness, weight loss, and cardiovascular/diabetes issues. It discusses the active ingredients in wheatgrass and their health benefits. Finally, contact information for the company is listed.
Autism enigma
This document provides biographical information about Dr. Cem Kinaci and discusses his background and experience in nuclear medicine. It also lists his professional affiliations with various medical organizations. The bulk of the document then covers topics related to autism spectrum disorder (ASD), including recognized tendencies, possible causes, predisposing factors, and biochemical effects associated with ASD.
Osteoporosis edited-100201092008-phpapp02
This document discusses osteoporosis, including its causes, risk factors, symptoms, diagnosis, and treatment. It describes osteoporosis as a systemic disease characterized by decreased bone strength and increased fracture risk. Key points made include:
- Osteoporosis has no symptoms until a fracture occurs and is known as the "silent epidemic".
- Risk factors include age, gender, family history, smoking, lack of exercise, and low calcium/vitamin D intake.
- Screening is recommended for women over 65 and younger women with risk factors using dual-energy x-ray absorptiometry (DEXA) scans.
- Treatment focuses on lifestyle changes like exercise, fall prevention, and calcium
FIBRO OSSEOUS LESIONS.pptx
1) Fibro-osseous lesions are a group of pathological changes where normal bone is replaced by fibrous tissue with or without calcification. The WHO classifies several types including ossifying fibroma, fibrous dysplasia, and cherubism.
2) Fibrous dysplasia is caused by a mutation in the GNAS1 gene and can be monostotic (one bone) or polyostotic (multiple bones). It is characterized by replacement of bone with fibro-osseous tissue.
3) Radiologically, fibrous dysplasia lesions appear radiolucent, radiopaque, or mixed depending on the site. In the jaws, lesions are often located in
Designer babies
The document discusses various genetic concepts including dominant and recessive alleles, traits being expressed in offspring from the combination of parental alleles, and different types of genetic disorders. It then discusses the concept of designer babies, including how genetic screening can reduce risks of diseases and disabilities in offspring. While designer babies allow for choosing traits, some argue it could lead to eugenics. The document concludes that designer babies may help prevent miscarriages and diseases.
Designer babies
The document discusses various genetic concepts including dominant and recessive alleles, traits being expressed in offspring from the combination of parental alleles, and different types of genetic disorders. It then discusses the concept of designer babies, including how genetic screening can reduce risks of diseases and disabilities in offspring. While designer babies allow for choosing traits, some argue it could lead to eugenics. The document concludes that designer babies may help prevent miscarriages and diseases.
Patterns of Inheritance
This document discusses patterns of inheritance and genetics terminology. It defines key terms like allele, genotype, phenotype, dominant and recessive traits. It explains Mendel's laws of segregation and independent assortment. It provides examples of monohybrid and dihybrid crosses using Punnett squares. It also discusses exceptions to Mendel's laws like incomplete dominance and codominance. Finally, it covers sex-linked inheritance and examples of X-linked disorders.
Saliva
Saliva is produced in the salivary glands and is mostly water. It contains electrolytes, mucus, enzymes and antibacterial compounds. Saliva keeps the mouth moist, aids in chewing, tasting and swallowing, and fights germs to prevent bad breath and protect teeth from decay. The amount of saliva produced varies from 2-4 pints per day depending on factors like how much one chews. Too little or too much saliva can be caused by various diseases, medications, or conditions that impact the salivary glands or nervous system. Saliva testing is also used for early drug detection due to its correlation with impairment.
"The Science of Aging" by Martin Borch Jensen
Slides from the inaugural Impact.tech seminar about the science of aging, healthspan and longevity. The presentation addresses questions such as: What is aging? Is aging treatable? What are the major biological processes that make up aging? What are the major breakthroughs in anti-aging science? How you can get involved in anti-aging as an entrepreneur or investor?
Impact.tech Launch Seminars are meant to give entrepreneurs and investors a launch into a topic where they can apply their skills to make a major positive impact for humanity and the world.
Similar to 2 rcio spreecast big picture (20)
Heirlooms, Hope Chests and Genes...What did you inherit?
Heirlooms, Hope Chests and Genes...What did you inherit?
More from The Raphael Center for Integrative Education
Ep 52 Spreecast pre show
This document provides information about multiple episodes of "The Airway and Facial Development Collaborative", a podcast produced by Drs. Mark A. Cruz and Barry Raphael. It lists the episode numbers, dates, guest speakers, and brief episode titles for over 50 past episodes dating back to January 2014. The episodes discuss various topics related to airway dentistry, sleep, breathing, orthodontics, posture, and interdisciplinary collaboration between dental and medical professionals.
Spreecast 51 amr algo
This document discusses respiratory and breathing physiology. It provides an overview of evaluating upper airway function, including tests like HRPO, pharyngometry, rhinometry, and CBCT. It also discusses treating conditions like UARS, LPR, and OSA with therapies like CPAP, OAT, MMA, and MFT. The document lists potential medical sequelae that can result from untreated airway and breathing issues, such as bruxism, anxiety, depression, fatigue, nocturia, hypertension, cognitive impairment, reflux, cough, asthma, mood swings, infertility, and more.
Spreecast 51 compensation
This document discusses airway and facial development, evolution, and how environmental stressors can lead to unintended physiological consequences and compromises. It explores the difference between competencies developed through genetic evolution and design, and compensations developed through environmental influences and stress, which can result in secondary dysfunctions. Specifically, it examines how competent behaviors and functions in children can be replaced by compensatory parafunctions due to environmental factors like mouth breathing, which can ultimately lead to malocclusions and other structural asymmetries if left unaddressed.
Ep 51 Spreecast pre show
This document announces an upcoming webinar titled "Current Topics in Airway Dentistry" hosted by The Airway and Facial Development Collaborative on June 13, 2016 at 9:30 EST. The webinar will be produced by Dr. Mark A. Cruz and Dr. Barry Raphael and will discuss evolution, Darwinian dentistry, competencies, stressors, physiology, and consequences as they relate to airway dentistry.
Spreecast 51 history
This document provides a brief history of myofunctional orthodontics, listing important contributors from 1850 to present day. It focuses on two pioneers: Wilhelm Roux, a German anatomist in the late 19th century who first conceptualized "Functional Orthopedics"; and Alfred P. Rogers, an orthodontist in the early 20th century who advocated total-child treatment including muscular exercises to improve posture and breathing. The document presents several of Rogers' publications from 1918-1926 where he emphasized the importance of muscle training and exercises alone in orthodontic treatment.
Spreecast 51 white flag
This document discusses bringing together different approaches to orthodontics that consider airway health, including Rogers MewAngleCrozat, myofunctional orthotropics, fixed appliances, and lightwire/cranial techniques. It advocates for interdisciplinary collaboration between orthodontics and other medical fields like pediatrics, musculo-skeletal medicine, and more to implement airway-conscious treatment protocols, improve diagnostics, and raise awareness of airway health issues. The goal is improved patient outcomes through validated multi-system diagnoses and addressing the epidemiology of airway problems.
episode 51 Spreecast post show
The document announces upcoming events on airway orthodontics and a new collaborative medical/dental care model. It provides information on upcoming spreecasts and mini-residency courses on airway assessment, causes of airway dysfunctions, treatment, and practice. It also includes a call for participants in a white flag initiative and invites people to subscribe to updates, provide feedback, and share invitations with others. It closes with a parting quote about evidence-based practice and the need for ongoing curiosity and discourse.
Farrell: Questioning orthodontics
Dr. Chris Farrell quotes some of the leading thinkers in modern orthodontics to question our conventional approach to the "problem" of malocclusion.
Ep 50 spreecast
This document discusses orthodontics and airway issues. It mentions that three orthodontists who attended an AARD meeting were curious about airway problems after one mentioned speakers on health and airway journeys. The friend spent two days promoting airway awareness and ALF programs, hoping other practitioners would understand the problems and solutions. The friend suggests crafting a vision for what they hope to achieve.
The document also lists researchers and outlines a research protocol studying the relationship between malocclusions, orofacial dysfunctions, and space conditions in primary and mixed dentition.
Ep 49 spreecast AFDC
This email from a friend discusses a presentation they saw that focused on mandibular advancement for correcting malocclusions. The friend critiques the presentation for overlooking important factors like tongue position and swallowing pattern. They believe the actual problem in the cases was a low resting tongue level caused by issues like tongue tie or bottle feeding rather than mandibular position. Correcting mandibular position without addressing the underlying tongue issues risks open bite recurrence and TMJ problems later in life. The friend argues the study design did not fully consider all impactful information needed to accurately reflect what was occurring.
Ep 48. Nordstrom pervasive power of 'p'
ALF originator, Dr. Darick Nordstrom, talks about the underpinning of his philosophy toward growth and wellness.
#48 Nordstrom Spreecast pre show
This document summarizes an episode of "The Airway and Facial Development Collaborative" podcast. The episode features Darick Nordstrom discussing the power of proper facial development. Nordstrom is a dentist from a rural practice who studied osteopathy and developed several appliance designs. He focuses on empowering practitioner teams through airway, sleep, and facial development techniques. The podcast is produced by Drs. Mark Cruz and Barry Raphael and covers topics related to the evolution of dentistry and its impact on facial development and physiology.
#48 Spreecast post show
The document announces an upcoming Spreecast event on April 25th featuring Mark Cruz and a guest discussing a new medical/dental care collaborative model. It also advertises upcoming airway mini-residencies on the east and west coast in June 2016 that will cover assessment, causes, treatment, and practice of airway-related dysfunctions. Finally, it provides parting words questioning the concept of evidence-based practice and calls for more curiosity and discourse on what remains unknown.
#47 Spreecast pre show
This document summarizes an upcoming webinar titled "Pat McBride: Reading the PSG and The DDS/MD Collaboration" hosted by The Airway and Facial Development Collaborative on March 28, 2016. The webinar will feature Pat McBride discussing how to read polysomnography reports and the collaboration between dentists and medical doctors. It provides details on McBride's background and experience in dental and sleep medicine. The webinar producers are listed as Dr. Mark A. Cruz and Dr. Barry Raphael.
#47 Pat McBrideSpreecast post show
The document contains announcements for upcoming events including a Spreecast on April 11th with Darick Nordstrom discussing stabilizing orthodontic patients and an event on April 25th with Mark Cruz on multidisciplinary wellness collaboratives. It also lists information on an airway mini-residency in June 2016 and a call for participants in the AAPMD White Flag initiative. Contact information is provided to subscribe, give feedback, and find out more information on the listed events and programs.
#47 Mc Bride spreecast 2016
This document discusses sleep scoring and interpretation. It begins by introducing the speaker and their background and disclosures in the field of sleep medicine. It then covers the basics of how sleep studies are scored, including scoring sleep stages, respiratory events, arousals, and periodic limb movements. It discusses the specifics of what is involved in scoring each of these components and provides examples. The document raises some issues that can arise in testing and reporting, and how failures in the system can negatively impact patients. It advocates for partnership between sleep professionals to better understand sleep disorders.
ep 46 Spreecast pre show
This document provides information about an upcoming episode of "The Airway and Facial Development Collaborative" podcast hosted by Drs. Mark Cruz and Barry Raphael. The episode scheduled for March 14th at 9:30 EST will focus on the legacy of James Garry and his contributions to the fields of dental occlusion and craniomandibular disorders. It will feature guests Clayton Chan and Ron Reeves discussing their history working with and being mentored by James Garry.
Ep 46 Spreecast post show
Clayton and Ron are thanked for something. An announcement is made about an upcoming webinar on March 28th with Pat McBride about working with medical offices. Another webinar is announced for April 11th with Mark Cruz on multidisciplinary wellness collaboratives. Information is provided about an upcoming airway mini-residency in June on both coasts covering assessment, causes, treatment, and practice regarding airway-related dysfunctions. Contact information is given for Darick Nordstrom and the AAPMD website. A call for participants is made for an AAPMD white flag initiative for orthodontists and others. Instructions are given to subscribe and pass invitations to others. Feedback can be provided to
Ep #46 Jim garry, dds v3
James F. Garry was considered the "Einstein of Dentistry" for his pioneering work in upper airway obstruction, upper airway deformities, and craniomandibular disorders. He helped develop technologies like the Nuk pacifier and aspirator. Garry was inspired by Dr. Bernard Jankelson, the father of neuromuscular dentistry, and began incorporating neuromuscular techniques after seeing their success in treating his sister's pain. Garry was a leader in the field who published extensively, lectured worldwide, and held many positions in professional organizations throughout his career.
Ep 45 Spreecast post show
The document announces upcoming events including a Spreecast on Dr. James Garry on March 14th and a talk by Pat McBride on working with medical offices on March 28th. It also advertises East and West Coast airway mini-residencies in June 2016 and the AAPMD White Flag conference in Tucson in September. It provides contact information for the events and asks readers to subscribe, pass on invitations, and provide feedback. It closes with a quote about arguing and listening.
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Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
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Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
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Ketone bodies and metabolism-biochemistry
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2 rcio spreecast big picture
- 1. Better Faces - Less Braces A Spreecast Webinar by Dr. Barry Raphael Of the Raphael Center for Integrative Orthodontics November 13, 2013
- 2. Don’t crooked teeth come from parents?
- 3. There was a time... 5,000 years ago Cavities and crooked teeth were rare!
- 4. Caries and Malocclusion are a product of Modern Life John Mew George Catlin James Sim Wallace Daniel Lieberman Westin Price Robert Corrucinni
- 6. Are we developing the way our genes meant us to be? Are Current Norms based on our developed Genotype? Or on current Phenotype?
- 7. The Results of the Mismatch Between Genes and the Environment Obesity Hypertension Cardiovascular Disease Caries Type 2 Diabetes Malocclusion Fatty Liver Disease Some Cancers Osteoporosis Sleep Apnea Metabolic Syndrome Asthma Autism Asperger’s Alzheimers ADD/ADHD Chronic Back Pain Depression Chronic Non-Communicable Diseases of Civilization Western Lifestyle Diseases
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- 11. The Broken Door
- 12. The Broken Door
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