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1How can you predict whether a BCL protein is pro-apoptotic?
a.Steady state localization to the mitochondria
b.Presence of an exposed BH3 domain
c.Presence of a BH4 domain
d. Can heterodimerize with other BCL proteins
e Presence of a BH3 domain
2. how does BCL-XL block apoptosis?
a.Binds to the proton transition pore
b Maintains electron transport through oxidative phosphorylation
c. Blocks the release of cytochrome C
d.Binds to BCL-2
e Blocks the loss of membrane potential

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Predict if BCL Protein Triggers Cell Death

  • 1. 1How can you predict whether a BCL protein is pro-apoptotic? a.Steady state localization to the mitochondria b.Presence of an exposed BH3 domain c.Presence of a BH4 domain d. Can heterodimerize with other BCL proteins e Presence of a BH3 domain 2. how does BCL-XL block apoptosis? a.Binds to the proton transition pore b Maintains electron transport through oxidative phosphorylation c. Blocks the release of cytochrome C d.Binds to BCL-2 e Blocks the loss of membrane potential